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Professor Heiner Bucher 

Visiting Professor

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Professor Heiner Bucher is Visiting Professor working in the School of Primary Care, Population Sciences and Medical Education within the Faculty of Medicine at the University of Southampton.

Professor Bucher is a clinical epidemiologist and internist at University of Basel, Switzerland. His research interest is in the implementation of evidence based medicine in clinical care with a particular focus on infectious diseases. He conducts studies in the area of comparative effectiveness research in different fields in medicine. He is known for the development of the first and widely used method for indirect comparison in meta-analysis (Bucher method).

Prof. Heiner C. Bucher is a clinical epidemiologist at the Department of Clinical Research, University of Basel and board certified internist with appointments at the Division of Infectious Diseases and Hospital Hygiene, University Hospital Basel. He received his clinical training at the University Hospital Basel and other clinics in Switzerland and training in epidemiology at the School of Public Health, University of California, Berkeley, USA, and in clinical epidemiology at the Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Canada.

Prof. Bucher has a long standing experience in HIV research where he has conducted numerous studies using large scale observational data and data from the Swiss HIV Cohort Study. In addition he has conducted several trials in primary care with the goal to optimize the use of antibiotics in respiratory tract infections. He has been involved in over 100 meta-analyses using direct and indirect comparisons and individual patient data meta-analyses to investigate the effectiveness of medical interventions in clinical trials. He has been very active in comparative effectiveness research using large scale routinely collected data and by designing innovative interventions in primary care with the use of pragmatic clinical trials.

Prof. Bucher has also been very active in Health Technology Assessments (HTA) in Switzerland and Germany. He has contributed the first and widely used method on indirect comparison (Bucher method) to the field of HTA. He has also been involved in methodological research, examining reasons for discontinuation of clinical trials and more recently in investigating the effectiveness of drugs with accelerated approval or of off-label drug use.

  • MD University of Basel 1983
  • FMH Internal Medicine 1985
  • MPH Epidemiology University of California, Berkeley 1988
  • Assistant professor University of Basel 1998
  • Full professor University of Basel 2003
  • FMH Public Health and Prevention 2014

Professor of Clinical Epidemiology, University of Basel 2001

Senior attending Division of Infectious Diseases & Hospital Hygiene 2001


  • Visiting Scholar Stanford Prevention Research Center, Stanford University, Palo Alto, USA
  • Visiting professor, Clinical Epidemiology MSc Programme Department of Clinical Epidemiology & Biostatistics McMaster University, Hamilton Canada 1994-1996
  • School of Public Health, University of California, Berkeley, USA 1988-1989
  • Internships and Board Certificate Internal Medicine FMH 1984-1988
  • School of Medicine, University of Basel 1975-1983


Research interests

Implementation of evidence-based medicine in clinical care to improve patient relevant outcomes. Applied research in infectious diseases to improve the use of antibiotics in primary care and patient outcome in patients with HIV infection. Comparative effectiveness research with use routinely collected data.

Research group

Primary Care, Population Sciences and Medical Education

Affiliate research group

Professor Heiner Bucher
Basel Institute for Clinical Epidemiology & Biostatistics, University of Basel and University Hospital Basel, Basel, Switzerland
Professor Heiner Bucher's personal home page
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