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The University of Southampton
Medicine
Email:
jay.amin@soton.ac.uk

Dr Jay Amin BM, MRCPsych, PhD

Associate Professor in Psychiatry of Older Age

Dr Jay Amin's photo

Dr Amin is an Associate Professor in Psychiatry of Older Age within Medicine at the University of Southampton. His research focus is on the role of inflammation in Dementia with Lewy bodies, Alzheimer’s disease and other neurodegenerative conditions. He is principal investigator for several commercial and non-commercial clinical trials in dementia and mild cognitive impairment at the Memory Assessment and Research Centre in Southampton.

Dr Amin graduated from medical school at Southampton in 2007 and completed his foundation programme training within Wessex. He undertook an NIHR Academic Clinical Fellowship between 2009-2012, following which he was awarded an Alzheimer’s Research UK Clinical Research Fellowship. His PhD project explored the role of inflammation in Dementia with Lewy bodies and Alzheimer’s disease, using both patient cohorts and post-mortem human brain tissue. Dr Amin joined the specialist medical register for Old Age Psychiatry after completing his higher clinical training in 2018.

In 2019 Dr Amin was appointed to his current role as Associate Professor in Psychiatry of Older Age for the University of Southampton. He is also an honorary consultant in Old Age Psychiatry at Southern Health NHS Foundation Trust, where he conducts memory clinics including providing a tertiary service for people with Dementia with Lewy bodies or Parkinson’s disease dementia.

Qualifications

BM, Medicine, University of Southampton, UK (2007)

MRCPsych, Royal College of Psychiatrists, UK (2012)

CCT in Old Age Psychiatry, Royal College of Psychiatrists, UK (2018)

PhD in Clinical Neurosciences, University of Southampton, UK (2019)

Appointments held

Associate Professor in Psychiatry of Older Age, University of Southampton (2019 onwards)

Honorary Consultant in Old Age Psychiatry, Southern Health NHS Foundation Trust (2019 onwards)

Alzheimer’s Research UK Clinical Research Fellow (2014-2017)

Principal Investigator at Memory Assessment and Research Centre, Southampton (2013 onwards)

Specialist registrar in Old Age Psychiatry, Health Education Wessex (2012-2018)

NIHR Academic Clinical Fellow in Old Age Psychiatry (2009-2012)

Core Psychiatry trainee, Wessex Deanery (2009-2012)

Foundation Programme trainee, Wessex Deanery (2007-2009)

 

Research interests

Dr Amin’s research interests focus on the role of inflammation in Dementia with Lewy bodies, Alzheimer’s disease and other neurodegenerative conditions. This includes exploration of the role of cerebral inflammatory markers in post-mortem brain tissue, and peripheral inflammatory markers using techniques such as multiplex immunoassay and flow cytometry. Other areas of interest include the role of the blood-brain barrier in mediating communication between peripheral and cerebral inflammation in dementia, and the role of the microbiome in the aetiology and progression of dementia.

Clinically, Dr Amin’s interests are in improving quality of life and outcomes in people living with dementia, and their carers. This includes using quality improvement methodology to drive forward service changes for the benefit of patients and carers.

Dr Amin is principal and sub-investigator for several commercial and non-commercial clinical trials at the Memory Assessment and Research Centre in Southampton. These include drug trials testing novel agents in Alzheimer’s disease (AD), Dementia with Lewy bodies (DLB) and Mild Cognitive Impairment (MCI).

Research group

Clinical and Experimental Sciences

Affiliate research groups

Clinical Neuroscience Research group, Memory Assessment and Research Centre

Postgraduate student supervision – current

  • Claire Gee 2021 – current

Southern Health NHS Foundation Trust

  • Academic lead for dementia research at the Memory Assessment and Research Centre

Royal College of Psychiatrists

  • Speciality representative (Old Age Psychiatry) for the South East Division
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Articles

Conferences

  • BMedSc and MMedSc project supervisor. Offer 1-2 clinical projects per year in dementia.
  • BM5 Year 2 teaching co-ordinator. Lead for Psychiatry teaching weeks in BM5 Year 2.
  • Personal academic tutor. Years 0-5.
  • University of Southampton. Examining (OSCE; ACC), interviewing (student selection, AFP/ACF), question setting, marking, lecturing.
  • Health Education Wessex/Southern Health NHS Foundation Trust. Clinical and educational supervisor for junior doctors. Co-lead of the Wessex OPMH academic meeting. Facilitator for postgraduate MRCPsych teaching on Dementia and Critical appraisal/statistics.
Dr Jay Amin
Memory Assessment and Research Centre, Tom Rudd Unit, Moorgreen Hospital, Botley Road, Southampton, SO30 3JB

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