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The University of Southampton
Medicine

Dr Mildred A Iro MBBS, MRCPCH, PgDip, DPhil

NIHR Academic Clinical Lecturer in Child Health and Genomics, Specialty Registrar in Paediatric immunology and infectious diseases

Dr Mildred A Iro's photo

Dr Mildred Iro, a National Institute for Health Research Clinical Lecturer in Genomic Medicine. She is also undertaking clinical training in paediatric immunology and infectious diseases.

She obtained a DPhil degree from the University of Oxford, UK in 2018. Mildred’s research during her DPhil was on childhood encephalitis. Working as a lead research fellow, Mildred co-ordinated the initiation and delivery of a large NIHR funded Phase 3 multi-centre randomised controlled efficacy trial of intravenous immunoglobulin in childhood encephalitis (IgNiTE). She also conducted encephalitis based epidemiological studies, and a Cochrane systematic review on encephalitis.

Prior to her DPhil programme, Dr Iro worked as a clinical research fellow with the Oxford Vaccine Group, UK and during this time was the lead clinical research fellow for various investigator led and commercial paediatric vaccine trials.

Following completion of her DPhil programme, Mildred was appointed as a NIHR Academic Clinical Lecturer at the University of Southampton, United Kingdom.

Dr Iro is currently undertaking research training in genomic medicine as part of her clinical lectureship. Her interest is in using genomics and transcriptomics to improve clinical phenotyping for a precision medicine approach for patients with severe infections and immunodeficiency.

She has published several articles and presented at numerous international and national level meetings. She is the recipient of the Lorber prize for the best paediatric publication for her work on childhood encephalitis admissions, published in The Lancet Infectious Diseases Journal in April 2017.

Qualifications

June 2018: DPhil in Paediatrics, St Cross College, University of Oxford, UK
Oct 2014: Postgraduate Diploma in Paediatric Infectious Diseases, University of Oxford, UK
Oct 2010: MRCPCH (UK)
Oct 2003: MB.BS University of Port Harcourt, Nigeria (Second class upper division)

Appointments held

Specialty trainee in Paediatrics, Wessex deanery (2007 -)
Clinical Research Fellow, Oxford Vaccine Group, Department of Paediatrics, University of Oxford (2012 – 2018)
DPhil candidate, Department of Paediatrics, University of Oxford (2013 – 2018)
Specialty (GRID) trainee in Paediatric immunology and infectious diseases  (2018 - )
NIHR Academic Clinical Lecturer in Genomics and Child Health (2018 -)

 

Research interests

Infectious diseases, immunology, genomics, transcriptomics, clinical trials, epidemiology

PhD title: Childhood encephalitis in the United Kingdom – epidemiology, trends in hospital admissions and the role of intravenous immunoglobulin

Research Projects

1.      Jan 2020 to date: Application of transcriptomic approaches in common variable immunodeficiency.  Principal Investigator, University of Southampton, UK

2.      Jan 2019 to date: Deep immuno-phenotyping to identify precision medicine targets in adult and paediatric patients with Primary immunodeficiency, Principal investigator, University of Southampton, UK

3.      2013 - Mar 2018: A phase III multi-centre randomised, double blind, placebo-controlled trial to assess the role of intravenous immunoglobulin in the management of children with encephalitis (The IgNiTE study) - Lead Clinical Research Fellow, University of Oxford, UK

2015 - 2017: Investigating the effect of Intravenous immunoglobulin (IVIG) treatment on the immunological and inflammatory response in encephalitis – Principal Investigator, Oxford Vaccine Group, University of Oxford, UK

Research group

Clinical and Experimental Sciences

• Member General Paediatrics Clinical Studies Group (2017- )
• Trainee representative: Academic Paediatrics Association of Great Britain and Ireland (2018 - )
• Member NIHR Reviewer development scheme (2018 -)
• Trainee representative: Child Health Research Trainee Group, University Hospital Southampton NHS Trust (2019 - )
• Trainee member - NIHR Efficacy and Mechanism Evaluation Programme Funding Committee (2020 - )
• Trainee representative elect: British Paediatric Allergy, Immunity, and Infection Group (January 2021 - )
• Peer reviewer for several journals

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Articles

Review

  • Regular lectures to undergraduate and postgraduate students
  • Personal Academic Tutor (2019 - )
  • Tutor – Medicine in Practice 2 (2018-19 academic year)
  • Assessor - Transfer viva  for PhD and MD students (2019, 2020)
  • Third year medical student project supervisor (2021-)
  • Assessment Marker – MSc Allergy Foundations (2020)
Dr Mildred A Iro
Faculty of Medicine, Room AB215, Mailpoint 801, South Academic Block, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD
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