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Dr Mark Lown BEng, PhD, MBBS, MRCGP

Clinical Lecturer

Dr Mark Lown's photo

Dr Mark Lown is a Clinical Lecturer within Medicine at the University of Southampton and a GP at Highfield Health in Southampton.

Dr Lown, recently held an NIHR in-practice fellowship at Southampton and has current interests in nutrition and cardiovascular medicine research in primary care. Being dual qualified as both an Engineer and GP, he also has a special interest in medical technology.

Dr Lown recently completed a positive trial investigating the effects of a plant extract (Mulberry) to reduce glucose and insulin rises following ingestion of carbohydrate. Current trials include a large multi-centre trial investigating probiotics to reduce infection rates and antibiotic resistance in care home residents (PRINCESS), a trial investigating blood pressure medication reduction in the elderly (OPTIMISE), an AF screening trial using consumer devices (SAFETY) and a retrospective cohort study evaluating the long-term effects of lengthy antibiotics.

Research interests

Please visit the Primary Care website

Additional research projects

Attack trial - local clinical lead for the ATTACK trial investigating aspirin for primary prevention of CVD in CKD patients 

SAFER - screening for Atrial Fibrillation with ECG to reduce stroke

Research group

Primary Care, Population Sciences and Medical Education

Affiliate research group

Research project(s)

4S Sore Throat Study (Scores and Swabs to Self-assess Sore Throats)

ATTACK: Aspirin to target arterial events in Chronic Kidney Disease

OPTIMISE - OPtimising Treatment for MIld Systolic hypertension in the Elderly

The population is getting older (over 3 million people [5%] in the UK are >80 years) and the number of people living with multiple long-term conditions taking multiple drugs is increasing. High blood pressure is one of the most common conditions in older patients and up to half of this population receive two or more drugs to treat it. However, recent evidence suggests that large reductions in blood pressure, and too many drug prescriptions may be associated with an increase in serious falls and death in the elderly.  

PRINCESS - Probiotics to reduce infections in care home residents, the PRINCESS trial

PROBITY - Prolonged Antibiotic Use, Inflammation and Obesity - a retrospective cohort study

This is a retrospective cohort study to investigate the long-term effects of prolonged antibiotic consumption on health.

Retrospective Survey of Prevention, Treatment, Occurrence and Outcomes of Covid-19 in the community (RTO-Covid-19)

This is a survey about what people have done to try and prevent and treat Covid-19 since the start of the pandemic.

SAFETY - Screening for Atrial Fibrillation using Economical and accurate TechnologY - a pilot study

This is a case-control study to investigate the accuracy of inexpensive commercial heart-rate/rhythm monitoring devices to detect Atrial Fibrillation (AF) in conjunction with a novel algorithm based on digital entropy.

Supporting Targeting Of antibiotics in Primary care to combat AMR using decision aids (STOP AMR – decision aids)

VENUS Study – Developing a new approach to managing care home residents with possible urinary tract infection 

PANORAMIC - Platform Adaptive trial of NOvel antivRals for eArly treatMent of COVID-19 In the Community

GP at Highfield Health, Southampton

PhD supervisor

Supervisor of medical BMedSci students

Faculty of Medicine Graduate School Committee member

RCGP Scientific Foundation Board member

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  • 4th year medical student projects
  • BM5 critical appraisal teaching
  • BM4 PBL facilitator
Dr Mark Lown
Primary Care and Population Sciences
Faculty of Medicine
University of Southampton
Aldermoor Health Centre
Aldermoor Close
SO16 5ST


Room Number : 9590 AHC/115/S2

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