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Professor Nicholas C W Harvey MA, MB, BChir, PhD, FRCP

Professor of Rheumatology and Clinical Epidemiology, Honorary Consultant Rheumatologist

Professor Nicholas C W Harvey's photo
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Professor Nicholas Harvey is Professor of Rheumatology and Clinical Epidemiology within Medicine at the University of Southampton.


1995 - BA (Hons), Physiological Sciences, University of Oxford
1997 - MB BChir, University of Cambridge
2001 - MRCP, Medicine, Royal College of Physicians         
2003 - Physiological Sciences, University of Oxford
2007 - PhD, University of Southampton
2008 - CCT, Rheumatology, PMETB
2015 - FRCP, Medicine, Royal College of Physicians

Appointments held

01/08/15 to present 
Professor of Rheumatology and Clinical Epidemiology & Honorary Consultant Rheumatologist, Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, University Hospital  NHS Trust, Southampton General Hospital, Tremona Road, SOUTHAMPTON SO16 6YD

01/10/2014 - 31/07/2015
Associate Professor in Rheumatology and Clinical Epidemiology, Honorary Consultant Rheumatologist, University Hospital Southampton

01/03/2011 – 30/09/2014
Senior Lecturer, University of Southampton; Honorary Consultant Rheumatologist, University Hospital Southampton

01/08/2008 – 28/02/2011
Senior Clinical Research Fellow, University of Southampton; Honorary Consultant Rheumatologist, University Hospital Southampton

26/02/07 – 01/08/2008
National Institute for Health Research Clinical Lecturer, University of Southampton

10/06 – 10/07 
Specialty Registrar Rheumatology, Christchurch Hospital

10/03 – 10/06
Clinical Research Fellow, MRC ERC/UoS

10/02 – 10/03
Specialty Registrar Rheumatology, Southampton General Hospital

10/01 – 10/02
Specialty Registrar Rheumatology, Salisbury District Hospital


Nicholas Harvey is Professor of Rheumatology and Clinical Epidemiology at the MRC Lifecourse Epidemiology Unit, University of Southampton, having originally trained in medicine at the Universities of Oxford and Cambridge. He is Chair of the International Osteoporosis Foundation Committee of Scientific Advisors, a Clinical Trustee of the UK Royal Osteoporosis Society (ROS) and Vice-Chair of the ROS Osteoporosis and Bone Research Academy. He leads an MRC programme focused on the lifecourse epidemiology of bone and joint disease. His work thus incorporates a lifecourse approach to characterisation of the epidemiology and determinants of osteoporotic fracture from cradle to grave, elucidation of underlying mechanisms, and development of novel interventions. He has won many national/international prizes, such as the National Osteoporosis Society Kohn Award and International Osteoporosis Foundation Medal of Achievement. He is an investigator on >£50m grant funding and has published over 225 peer-reviewed papers. He serves the UK and global field as a member of the American Society for Bone and Mineral Research Professional Practice Committee, the UK National Osteoporosis Guideline Group Advisory Committee, Royal Osteoporosis Society (UK) Scientific Programme Committee, Bone Research Society (UK) Committee (2014-2018), UK Biobank Imaging Working Group (leading the DXA assessment of 100,000 individuals), Versus Arthritis Progress Review Committee and NIHR Research for Patient Benefit Regional Advisory Board (2016-2019). He serves as an associate editor for Archives of Public Health, and on the editorial boards of Bone and Osteoporosis International. He reviews regularly for JBMR, Bone, Osteoporosis International, Lancet, BMJ, NEJM, and for funding bodies such as UK Medical Research Council, BBSRC, EPSRC, Wellcome Trust, NIHR and INSERM.

Research interests

Prof Harvey’s research achievements include:

  1. Comprehensive characterisation of the UK descriptive epidemiology of fractures, and related mortality and medication use (Curtis et al., Bone 2016; Moon et al., Bone 2016; van der Velde et al., Osteoporos Int 2016; Klop et al., Bone 2014; van der Velde et al., Bone 2017; Klop et al. Osteoporos Int 2017);
  2. Confirmation that low maternal 25(OH)-vitamin D concentration during pregnancy is associated with reduced bone mass in the offspring (Harvey et al., JCEM 2008; Javaid et al., Lancet 2006; Mahon et al., JBMR 2010);
  3. Demonstration that maternal vitamin D supplementation during pregnancy improves offspring bone mass amongst winter births (Cooper, Harvey et al., Lancet DE 2016);
  4. Characterisation of 25(OH)D across pregnancy and determinants of response to treatment (Moon et al., AJCN 2016; Moon et al., JCEM 2017);
  5. Description of relationships between growth in utero, measured using gestational ultrasound scanning, and skeletal development in childhood (Harvey et al., JBMR 2010, Harvey et al., PPE 2012; Harvey et al., Ped Res 2013);
  6. Elucidation of aetiological factors underlying these epidemiological observations, such as the relationship between placental calcium transporters and offspring bone mass (Martin et al., Bone 2007), and epigenetic regulation of genes in umbilical cord (Harvey et al., CTI 2012; Harvey et al., JBMR 2014; Curtis et al., JBMR 2017; Curtis et al., JBMR 2018);
  7. Demonstration that bariatric surgery does not appear to increase fracture risk, at least up to 5 years post-surgery (Lalmohamed et al., BMJ 2012).
  8. Demonstration of efficacy of teriparatide across baseline fracture risk distribution (Harvey et al., Osteoporos Int 2015a and b)
  9. Characterisation of falls, physical performance and muscle related measures as risk factor sfor future falls and fractures (Harvey et al., Osteoporos Int 2015; Harvey et al., JBMR 2018a; Harvey et al., JBMR 2018b; Harvey et al., Osteoporos Int. 2019)

  10.  Elucidation of reassuring lack of association between calcium supplementation and cardiovascular events in the UK Biobank (Harvey et al., JBMR 018) and elucidation of bone-cardivascular relationships (Harvey et al., Osteoporos Int. 2018)

  11. Demonstration that systematic screening for osteoporosis in primary care increases uptake of, and adherence to, antiosteoporosis medications (Parsons, Harvey et al., Osteoporos Int. 2020)

For further information regarding the MRC Lifecourse Epidemiology Unit (Director, Professor Cyrus Cooper), please go to:


Human Development and Health

Affiliate Department(s)

Human Development and Physiology

Research project(s)

Epigenetic mechanisms in metabolic bone disease: from pathology to biomarker

Identification of perinatal epigenetic markers of later phenotype

2006-current Grant reviewer for MRC, Arthritis Research UK, NOS, INSERM

2006-current Reviewer for Osteoporosis International, Bone, JBMR, JCEM, BMJ, Lancet, NEJM   

2006-2008  External lecturer, Guys and St Thomas Hospital

2006-2010  Bone Research Society Committee

2008-2013  British Nutrition Foundation Task Force

2008-current  UK Biobank Imaging Working Group (DXA Lead)

2008-current  National Osteoporosis Society Scientific Programme Committee

2011-current  IOF Committee of Scientific Advisors

2012-current  Editorial board member: Bone

2013-current  Editorial board member: Osteoporosis International

2011-current  Editorial board member: Archives of Public Health

2010-current  Academic Editor: Frontiers in Bone Endocrinology

2011-2018     Academic Editor: PLOSone

2010-2014     NIHR HTA Faculty

2014-2018     Bone Research Society Committee

2015-current  Arthritis Research UK Progress Review Committee

2016-2019     NIHR RfPB Regional Advisory Panel

2018-current  American Society for Bone and Mineral Research Professional Practice Committee                                                                       

2017-2019     Vice-chair, IOF Committee of Scientific Advisors

2019-current  Vice-chair, Osteoporosis and Bone Research Academy, Royal Osteoporosis Society                                                                          

2019-current  Clinical Trustee, Royal Osteoporosis Society

2019-current  Chair, IOF Committee of Scientific Advisors

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Book Chapters



Oversees / provides 4th and 5th year rheumatology teaching

Contributes to Academic F2 teaching programme

Lecture BM4 Course, MMedsci Course

Professor Nicholas C W Harvey
MRC Lifecourse Epidemiology Unit (University of Southampton) Southampton General Hospital Southampton SO16 6YD Email: Tel: +44 (0) 23 8077 7624 Tel: +44 (0) 23 8070 4021 PA: Mrs Ruth Fifield Email: Tel: +44 (0) 23 8076 4027 Fax: +44 (0) 23 8070 4021

Room Number: SGH/MRC/MP95

Telephone:(023) 8077 7624
Facsimile:(023) 8070 4021

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