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The University of Southampton
(023) 8120 5167

Mr Rahul Bhome BSc, MBBS, PhD, MRCS, MAcadMEd

NIHR Clinical Lecturer in Surgery

Mr Rahul Bhome's photo

Tumour-host interaction in colorectal cancer

Mr Bhome qualified in Medicine from UCL Medical School with distinction, having received a first class intercalated BSc in pharmacology. His undergraduate research investigated inflammatory signalling in adipose tissue. Based on this early academic experience, he was appointed to an Academic Foundation post at Imperial College in 2010, followed by an NIHR Academic Clinical Fellowship in General Surgery at the University of Southampton in 2012. Subsequently, in 2015, he obtained CRUK Clinical Research Fellowship to complete a PhD under the supervision of Professor Alex Mirnezami at the Southampton CRUK Centre. This was supplemented by award of an MRC Clinical Research Training Fellowship in 2017. Upon completion of his PhD, Mr Bhome was appointed to an NIHR Clinical Lecturer post (2019), the first part of which he spent as a Crick CRUK Clinical Postdoctoral Fellow in Erik Sahai's lab at The Francis Crick Institute.

Mr Bhome's research interests are in the field of tumour microenvironment, specifically the crosstalk between colorectal cancer cells and the stroma. He has published several articles and book chapters on cancer-associated fibroblasts, exosomes and microRNAs and has presented at numerous international meetings. His work has received additional grant funding from the British Council (Nanoscience Fellowship) and the European Union (COST Fellowship), which has allowed him to collaborate with researchers at Tel Aviv and Ghent universities.


BSc (First Class Honours), Medical Sciences with Pharmacology, UCL, 2007
MB BS (Distinction), UCL Medical School, 2010
MRCS, Royal College of Surgeons (England), 2012
PhD, Cancer Sciences, University of Southampton, 2019

Appointments held

ACF in General Surgery (2012-2015)
CRUK Clinical Research Fellow (2015-2017)
MRC Clinical Research Training Fellow (2017-2019)
Crick CRUK Clinical Postdoctoral Fellow (2019)
NIHR Clinical Lecturer in Surgery (2019-)
Honorary Specialty Registrar in General Surgery (2015-)

Research interests

Colorectal cancer; Tumour microenvironment; Cancer stroma; Cell-cell communication

PhD Project (2015-2018): The role of exosomes in tumour-stroma interaction in colorectal cancer.

Postdoctoral project (2019-): Investigating micrometastatic colorectal cancer in the liver using a mass cytometry approach

Research group

Cancer Sciences

Affiliate research groups

Sahai Lab, The Francis Crick Institute, DeWever Lab, Cancer Research Institute Ghent, Ghent University, Shomron Lab, Sackler Faculty of Medicine, Tel Aviv University

Examiner – Final BMBS OSCE, University of Southampton (2014 - )
Final BMBS examination standard setting committee, University of Southampton (2017 - )
Supervisor - MMedSci students, University of Southampton (2014-2015, 2016-2017)

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Book Chapters


Medicine in Practice Facilitator, University of Southampton Medical School (2016-2017)
Year 3 BM Surgical Tutor, University of Southampton Medical School (2013-2014)

Mr Rahul Bhome
Faculty of Medicine, Room AB215, Mailpoint 801, South Academic Block, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD

Room Number : SGH/CSB/MP824

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