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The University of Southampton
Micro and Nano Therapies

Mr Jonathan  May PhD

Postdoctoral Research Student

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Jon completed his PhD in Organic Chemistry in the lab of Prof Tom Brown at Southampton University, UK. This project investigated oligonucleotide probes for genetic analysis and received a CASE award from the biotech company, Eurogentec, who developed this work into a commercial product (part of their Deep Dark Quencher range).

Jon was then awarded a postdoctoral fellowship from The Royal Society to travel to the west coast of Canada and investigate DNAzymes (enzymes made out of modified DNA) and bicyclic peptide synthesis (the amatoxins and phallotoxins) at the University of British Columbia (Vancouver) in the lab of Prof David Perrin. Following this postdoc, Jon was hired by a translational research company, the Centre for Drug Research and Development (CDRD) also in Vancouver, where he worked in the Medicinal Chemistry and Formulation Development teams on a range of projects of different drug classes. This experience then led to another postdoctoral position studying Nanomedicine at the Ontario Institute for Cancer Research (Toronto, Canada). Here, Jon pursued an interest in stimulated-release formulations for cancer under the supervision of Dr Shyh-Dar Li, where a particular focus was a temperature-sensitive liposome called HaT (Heat activated cytoToxic).

Jon then returned to the UK, where he took a position at the Northern Institute for Cancer Research (NICR), Newcastle, studying peptide-drug conjugates, before taking on his current position at the University of Southampton as part of the EPSRC Bubble For Bone group; a collaboration between the Universities of Oxford and Southampton (current supervisors: Dr Nick Evans, Dr Dario Carugo and Prof Eleanor Stride). Jon is currently studying different ultrasound sensitive formulations and their ability to deliver payload to bone fracture sites in vivo.

Research interests

  • Stimuli-sensitive drug release from drug delivery vehicles
  • Nanomedicine to promote bone healing
  • Microbubbles for oxygen delivery
  • Phase change Nanodroplets for theranostic applications

Research group

Bioengineering Science

Affiliate research groups

Human Development and Health, Micro and Nano Therapies (MiNaTher)

Mr Jonathan May
Human Development and Health Academic Unit
Faculty of Medicine
Institute of Developmental Sciences Building (MP 887)
University of Southampton
Southampton General Hospital
Tremona Road
Southampton
SO16 6YD

Room Number: SGH//MP887


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