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The University of Southampton
Micro and Nano Therapies

Interventional Medicine

When assessing the efficacy of new drugs and medical devices, it is essential that real-life conditions are replicated accurately before in vivo testing. Whilst it is essential to understand the biological effects of therapeutic compounds or devices under normal physiological conditions, it is equally as important to evaluate how these may be altered in disease states. One of our branches of interventional medicine develops physiological and pathological models of the human vasculature, which facilitates research to evaluate the efficacy and pharmacokinetics of therapeutic agents. The second branch uses computational and experimental models, to investigate the role of flow dynamics on the formation of encrustation and biofilms in endourological devices.

Urological Devices

Urological Devices

There are several clinical complications associated with the deployment of endourological devices (e.g. ureteric stents), particularly caused by encrustation and bacterial biofilm formation...

Vascular Therapies

Vascular Therapies

Sclerosants administered intravenously as micro-foams, are an established therapy for varicose veins...

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