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The University of Southampton
Global Network for Anti-Microbial Resistance and Infection Prevention

Awards announced for first NAMRIP Pump Priming Competition

Published: 21 September 2015
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Innovation and Approach - the Network for Antimicrobial Resistance and Infection Prevention

Four projects successfully achieved funding in the first round of the NAMRIP Pump Priming Competition. All 4 projects demonstrated how they will ‘bridge the gap’ between engineering and physical science (EPS) and non-EPS research and bring together new collaborators across the University to tackle the issue of Antimicrobial Resistance.

The 4 projects funded are:-

  1. ‘Prevention of Pneumococcal Biofilm Formation on Tympanostomy Tubes to Combat AMR’. Project team – Dr Raymond N. Allan, Prof Saul N. Faust, Dr Simon Dennington and Prof Paul Stoodley.
    This project involves research into new coatings that can be applied to tubes used in the treatment of ear infections. The aim is to prevent bacteria forming on the tubes, which in turn will reduce infections and the need for antibiotics.

  2.  ‘Evaluation of cross-linked quaternised polyethyleneimine as a potential antimicrobial catheter material.’ Project team - Dr. Simon Dennington, Prof. M Fader, Prof. CW Keevil, Dr SA Wilks and Prof. R. Wood.
    The formation of bacteria on catheters can lead to urinary tract infections and subsequent complications to health. The team will formulate and test new catheter materials. The anti-microbial properties of the new materials will be compared against existing silicone catheters.

  3.  ‘Does fucose inhibit Pseudomonas aeruginosa colonisation of ciliated airway epithelium?’ Project team - Dr Claire Jackson, Dr Peter Lackie, Prof Bruno Linclau, Mr Rob Szpera, Dr Elizabeth Adam, Dr Raymond N. Allan and Dr Robert Howlin. Bringing together Chemists and Biologists, this project will investigate using simple sugars to combat bacterial infection.

  4.  ‘Integrating the 3-dimensional bioelectrospray cell culture model with a microfluidic platform to model real-time physiological changes.’ Project team – Dr Xunli Zhang and Dr Paul Elkington. The project will support the design and construction of a novel microfluidic device. Within the lab, the device will allow antibiotic concentrations, in the treatment of tuberculosis,  to be varied over time to mimic changes that occur in a patient after taking antibiotics.

Notes for editors

NAMRIP is funded by the University of Southampton and benefits hugely from £868,704.00 of funding from EPSRC's Network for Antimicrobial Action 'Bridging the Gap' call (EP/M027260/1).

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