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The University of Southampton
Global Network for Anti-Microbial Resistance and Infection Prevention

BRC and Global-NAMRIP allocate £100K to five new projects tackling AMR

Published: 6 January 2020
Southamptons Clinical Research

Following an open competition, the NIHR Southampton Biomedical Research Centre (BRC) in collaboration with Global-NAMRIP are delighted to announce that five new projects have successfully secured funding. Projects will commence in January 2020 and are due to complete by June 2021 at the latest.

All the submitted projects were judged against a pre-set list of criteria which included linking engineering and physical sciences with Antimicrobial Resistance and the research having a patient focus with direct translational projects being favoured. The judging panel was chaired by Professor Rob Read, Director of the NIHR Southampton BRC.


The five projects allocated funding are:

  • ‘Integrating novel lateral flow technology with emerging biomarkers to combat antimicrobioal resistance in tuberculosis’. Project Team - Dr Colin Sones (PI), Prof Paul Elkington and Prof Robert Eason. This project brings together a novel laser pattering technology developed within the Optoelectonics Research Centre led by Dr Sones and Prof Eason with Prof Elkington’s research identifying novel biomarkers of TB to produce a prototype device for population screening of TB.
  • 'Rapid antimicrobial susceptibility testing of urinary tract infections’. Project Team - Prof Hywel Morgan (PI), Dr Nitin Mahobia, Dr Mark Sutton and Dr Daniel Spencer. The team will evaluate their existing rapid antimicrobial susceptibility test (AST) in informing the selection and use of antibiotics for treating patients with urinary tract infections in a hospital setting (including Intensive Care Units and high dependency wards).
  • 'Does irrigating chronic wounds with a liquid acoustic stream (LAS) improve healing?’. Project Team - Dr Callum Highmore & Prof Tim Leighton (Joint PI’s), Dr Kit Harling and Dr Tom Secker.  This multidisciplinary collaboration will take LAS from the laboratory to the bedside by using LAS on patients with chronic wounds, with the results informing a clinical trial.
  • 'Novel Raman Spectroscopic Analysis for In Situ Detection of AMR in Cystic Fibrosis’.  Project Team - Dr Callum Highmore (PI), Prof Sumeet Mahajan, Prof Saul Faust and Prof Jeremy Webb. The team will develop a Raman signature ‘library’ to enable AMR identification in patients with Cystic Fibrosis.
  • 'Developing a portable sensor device for continuous monitoring of antimicrobials in body fluids’. Project Team - Dr Xize Niu (PI) and Prof Mike Grocott. Building on existing wearable/portable microfluidic sensor technology, this project will develop a handheld device for monitoring antimicrobials in patients.

An update on each project will be available on our research pages in the Spring.

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