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The University of Southampton
Global Network for Anti-Microbial Resistance and Infection Prevention

Understanding the mechanism and activity of a novel biocide product

Daniel Noel, a postgraduate research student in the Faculty of Environmental and Life Sciences, presented this research at the Global-NAMRIP Festival of Early Career Research on 25 June 2019. The poster can be downloaded via the 'Useful Downloads' link below.

Dan Noel Poster

Healthcare associated infections account for hundreds of millions of infections worldwide every year. Biocides are widely used as an infection control measure, however their effectiveness is being limited by the increasing prevalence of antimicrobial resistance.

It has been proposed that complex multi-component biocides could be used that act via multiple mechanisms of action. Bacteria would therefore need to develop resistance to multiple mechanisms simultaneously; potentially mitigating and slowing down the rate of resistance development.

“SQ53” is a multi-component formulation made up from commercially-available biocides. The formulation demonstrates a very high level of activity, indicating a potential synergistic mechanism. 

The aim of this project is to investigate various biocide mixtures for potential synergism, aiming to optimise the biocides that are currently used and widely available.

The authors of this research are Daniel Noel and Charles Keevil from Biological Sciences and Sandra Wilks from Health Sciences.

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