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The University of Southampton

New testing device can detect COVID-19 in 15 minutes

Published: 10 September 2020
Diagnostic Strip
A testing strip works in a similar way to a pregnancy test

A new diagnostic test, developed at the University of Southampton, could provide rapid, inexpensive testing of COVID-19 recent trials have shown.

Current testing using the standard PCR test requires samples to be sent to a laboratory which means results are not available until one or two days later.

The new test, developed by the University’s Zepler Institute for Photonics and Nanoelectronics (ZIPN), can detect the presence of the SARS-CoV-2 virus which causes COVID-19 in 10 – 15 minutes.

The test involves taking a patient’s nasal swab and mixing it with a solution in a tube. Working in a similar way to the commonly available pregnancy test, a paper strip containing a capture antibody is then dipped into the tube to absorb the solution. As the liquid moves up the strip, a red line will appear if the virus is present in the sample.

The University's Faculty of Medicine have carried out trials using 150 patient swabs, 125 of which had tested positive with a PCR test and 25 that had tested negative. The results showed the new product can reliably detect COVID-19 in individuals with moderate to high viral levels, the most infectious patients.

The team are now in discussions with manufacturers who would be able to produce the test at scale and begin the process for obtaining the necessary regulatory approvals.

If the product is widely produced it could be rapidly deployed to clinics and GP surgeries as a point-of-care test which would relieve the high demand currently being experienced by PCR testing centres. The low cost of the product could also pave the way for large-scale testing of individuals in schools, airports or businesses.

Dr Collin Sones, the ZIPN lead said: “A cheap rapid test such as ours could complement existing tests being used to control the spread of virus. Its key strength is that it can be used at home by anyone, making daily testing of the population an achievable reality. The individuals whose samples were identified as positive by our test would be the ones more likely to spread the disease because of their high viral loads.”

The team received funding from the EPSRC's Impact Acceleration Account and the ZIPN Stimulus Fund to progress their work to test and develop the product.

Diagnostic Test2
A red line indicates a positive test
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