About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Sponsor: Medical Research Council
Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: EPSRC
Completed projects
Researchers:
Researchers:
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Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: Wessex Medical Research
Publications
61 publications
Page 3 of 7
Despo Polyviou,
Moritz Machelett,
Andrew Hitchcock,
Alison Baylay,
Fraser MacMillan,
C. Mark Moore,
& Ivo Tews
, 2018
, The Journal of Biological Chemistry
, 293 , 18099--18109
Type: article
Emma, Jill Sutton,
Richard Bradshaw,
Christian Orr,
Björn Frendéus,
Gunilla Larsson,
Ingrid Teige,
Ivo Tews,
, 2018
, Biophysical Journal
, 115 (2) , 289--299
Type: article
Xiaojie Yu,
Christian Orr,
Osman Dadas,
Steven Booth,
Lekh Dahal,
Christine Penfold,
Lyn O'Brien,
Christopher Mockridge,
Ruth French,
Leon Douglas,
Arwen R. Pearson,
Ivo Tews,
Martin Glennie,
& Ann L. White
, 2018
, Cancer Cell
, 33 (4) , 664--675
Type: article
Jane Willoughby,
Jordana Griffiths,
, 2017
, Molecular Immunology
, 83 , 13--22
Type: article
Matthew J. Rodrigues,
Volker Windeisen,
Yang Zhang,
Gabriela Guédez,
Stefan Weber,
Marco Strohmeier,
Jeremiah W. Hanes,
Antoine Royant,
Gwyndaf Evans,
Irmgard Sinning,
Steven E. Ealick,
Tadhg P. Begley,
& Ivo Tews
, 2017
, Nature Chemical Biology
, 13 (3) , 290--294
Type: article
Dom Bellini,
Sam Horrell,
Andrew Hutchin,
Curtis W Phippen,
Richard W Strange,
Yuming Cai,
Armin Wagner,
Ivo Tews,
& Martin A Walsh
, 2017
, Scientific Reports
, 7 , 42166
DOI: 10.1038/srep42166
Type: article
Andrew Chancellor,
Anna Tocheva,
Christopher Cave-Ayland,
Andrew White,
Juma'a Al Dulayymi,
John Bridgeman,
Ivo Tews,
Susan Wilson,
Nikolai Lissin,
Marc Tebruegge,
Sally Sharpe,
Timothy Elliott,
Mark Baird,
Stephan D. Gadola,
, 2017
, Proceedings of the National Academy of Sciences
, 114 (51) , E10956--E10964
Type: article
Anna Tocheva,
Chris Cave-Ayland,
Moritz M. Machelett,
Barbara Sander,
Nikolai M. Lissin,
Peter E. Molloy,
Mark S. Baird,
Gunthard Stubs,
Nicolas W.J. Schroder,
Ralf R. Schumann,
Jorg Rademann,
Anthony D. Postle,
Bent K. Jakobsen,
Rajendra Gosain,
Tim Elliott,
Ivo Tews,
& Stephan D. Gadola
, 2016
, Proceedings of the National Academy of Sciences
, 113 (9) , E1266--E1275
Type: article
Andrew James Hutchin,
Dom Bellini,
Sam Horrell,
Curtis Phippen,
Yuming Cai,
Richard W. Strange,
Armin Wagner,
Martin A. Walsh,
& Ivo Tews
, 2016
, Acta Crystallographica Section A: Foundations and Advances
, 72 (Supplement 1) , S39--S40
Type: conference
Ivo Tews,
& Jon Cooper
, 2015
, Acta Crystallographica Section D: Biological Crystallography
, 71 , 1--2
Type: article
Pagination
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)