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Doctor Adnan Khan

 BSc, MB BS, PhD, FRCOphth
NIHR Clinical Lecturer in Ophthalmology

Research interests

  • Age-Related Macular Degeneration
  • Ocular Immunology
  • Immunosenescence

More research

Connect with Adnan

Email: a.h.khan@soton.ac.uk

Address: Southampton General Hospital, Tremona Road Shirley, SO16 6YD (View in Google Maps)

ORCID
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Profile photo
Upload your profile photo in Subscribe (opens in a new tab). Your profile photo in Pure is not linked to your public staff profile. Choose a clear, recent headshot where you are easily recognisable. Your image should be at least 340 by 395 pixels. 

Name
To change your name or prefix title contact Ask HR (opens in new tab)  If you want to update an academic title you'll need to provide evidence e.g. a PhD certificate. The way your name is displayed is automatic and cannot be changed. You can also update your post-nominal letters in Subscribe (opens in a new tab).

Job title
Raise a request through ServiceNow (opens in a new tab) to change your job title (40 characters maximum) unless you're on the ERE career pathway. If you're on the ERE path you can not change your main job title, but you can request other minor updates through Ask HR (opens in new tab). If you have more than one post only your main job title will display here, but you can add further posts or roles in other sections of your profile.

Research interests (for researchers only)
Add up to 5 research interests. The first 3 will appear in your staff profile next to your name. The full list will appear on your research page. Keep these brief and focus on the keywords people may use when searching for your work. Use a different line for each one.

In Pure (opens in a new tab), select ‘Edit profile’. Under the heading 'Curriculum and research description', select 'Add profile information'. In the dropdown menu, select 'Research interests: use separate lines'.

Contact details
Add or update your email address, telephone number and postal address in Subscribe (opens in a new tab). Use your University email address for your primary email. 

You can link to your Google Scholar, LinkedIn and Twitter accounts through Pure (opens in a new tab). Select ‘Edit profile’.  In the 'Links' section, use the 'Add link' button. 

ORCID ID
Create or connect your ORCID ID in Pure (opens in a new tab). Select ‘Edit profile’ and then 'Create or Connect your ORCID ID'.

Accepting PhD applicants (for researchers only)
Choose to show whether you’re currently accepting PhD applicants or not in Pure (opens in a new tab). Select ‘Edit profile’. In the 'Portal details' section, select 'Yes' or 'No' to indicate your choice. 

About Research Publications Supervision Teaching External roles and responsibilities Biography
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About

Dr Adnan Khan is the NIHR Clinical Lecturer in Ophthalmology at the University of Southampton. He is undertaking ‘bench-to-bedside’ research into the immunological basis of sight-threatening eye diseases, including Age-Related Macular Degeneration (AMD). He is a clinician-scientist in training, combining research with higher specialty training in ophthalmology.

 

Adnan joined the University of Southampton in 2019. His passion for medical research developed at University College London (UCL) Medical School, where he interrupted his medical studies to undertake an intercalated PhD in transplantation immunology with Professors Andrew George MBE and Giovanna Lombardi at Imperial College London. He investigated the use of dendritic cell immunotherapy to induce donor-specific transplantation tolerance. Adnan demonstrated that dendritic cells (the body’s ‘professional’ antigen-presenting cells), modified using lentiviral vectors to inhibit co-stimulation to alloreactive T cells, can prevent corneal graft rejection. This was mediated by the generation of antigen-specific regulatory T cells (Tregs). The research was funded by the Roche Organ Transplantation Research Foundation (ROTRF), a registered medical research charity based in Switzerland. Adnan was awarded The Transplantation Society (TTS) International Young Investigator Award in 2008 for this work.

 

Adnan undertook further research in transplantation immunology as an Academic Foundation Doctor in Professor Kathryn Wood’s Transplantation Research Immunology Group (TRIG) at the University of Oxford before entering Ophthalmology training in Scotland. At Aberdeen Royal Infirmary, he became a co-investigator of clinical trials in uveitis, working together with a team of clinician-scientists in the department of ophthalmology.

 

He is currently working with Professor Andrew Lotery at the University of Southampton to elucidate the inflammatory mechanisms underlying the development of Age-Related Macular Degeneration (AMD). AMD is predicted to affect 288 million people worldwide by 2040, with no curative treatments currently available for this progressive disease that results in loss of central vision.

How to update your 'about' section

You can update this in Pure (opens in a new tab). Select ‘Edit profile’. Under the heading and then ‘Curriculum and research description’, select ‘Add profile information’. In the dropdown menu, select - ‘About’.

Write about yourself in the third person. Aim for 100 to 150 words covering the main points about who you are and what you currently do. Clear, simple language is best. You can include specialist or technical terms.

You’ll be able to add details about your research, publications, career and academic history to other sections of your staff profile.

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