Spontaneous low frequency resting state EEG and ADHD Seminar

This network has been termed a ‘default mode’ (DM) of brain activity and is characterised by spontaneous, low frequency activity (<0.1 Hz) in the precuneus/posterior cingulate cortex, the medial prefrontal cortex and the medial, lateral and inferior parietal cortex (Sonuga-Barke and Castellanos, 2007). The default-mode interference hypothesis (Sonuga-Barke and Castellanos, 2007) postulates that intrusions from spontaneous very low frequency brain activity, characteristic of the resting brain, may be responsible for lapses in attention and more specifically the increased performance variability commonly observed in ADHD. Although there is mounting fMRI evidence of resting state disconnectivity within DM regions in ADHD patients, a more direct and temporally informative measure of neuronal activity, DC EEG, can also be used to investigate very low frequency (VLF) oscillatory activity in the brain. Here we report findings from three independent datasets, showing attenuated power in VLF oscillations in participants with high non-clinical symptoms of ADHD as well as an adolescent sample with a clinical diagnosis.

Tea will be served beforehand at 15:45 in room 3096 (iZone room).