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The University of Southampton
Psychology

Research project: Association Between Mental Disorders and Somatic Conditions: an umbrella review

Currently Active: 
Yes

Several studies, and meta-analyses of them, have been conducted on the association between mental and physical conditions. However, a comprehensive umbrella review of current meta-analyse is lacking. This umbrella review aims to pool all the relevant literature on this topic to assess to which extent the association is disorder specific or it is transnosographic.

We will conduct an umbrella review of SRs/MAs to test: 1) the strength of the association between individual mental disorders and individual somatic conditions in children/adolescents and adults; 2) to which extent associations are specific to individual mental and somatic conditions . Methods and analysis We will search a broad set of electronic databases and contact study authors. We will include SRs with MA or SRs reporting the effect size from individual studies on the association between a number of somatic and mental conditions (as per the International Classification of Diseases, 11th Revision).

We will follow an algorithm to select only one SR or MA when more than one are available on the same association. We will rate the quality of included SRs/MAs using the AMSTAR-2 tool. We will assess to which extent mental disorders are selectively associated with specific somatic conditions or if there are transdiagnostic, across-spectra or diagnostic spectrum-specific associations between mental disorders and somatic conditions based on the Transparent, Reporting, Appraising, Numerating, Showing (TRANSD) recommendations.

 

Associated research themes

National Library of Medicine

Related research groups

Centre for Innovation in Mental Health (CiMH)
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