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Research project

H2020 RIA IMI2-rapiD and secuRe AI imaging based diaGnosis, stratification, fOllow-up, and preparedness for coronavirus paNdemics.-DRAGON

Staff

Lead researcher

Professor Diana Baralle B.Sc., M.B.B.S, M.D, FRCP

Associate Dean Research

Research interests

  • RNA
  • Splicing

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Other researchers

Professor Ratko Djukanovic

Professor of Medicine

Research interests

  • Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where his focus is on: 1) underlying pathobiological mechanisms of asthma, 2) stratification of asthma into clinical phenotypes and mechanism-based endotypes, 3) unmet needs of severe asthma management. He also has an interest in the mechanisms and treatments of severe viral infections of the lung.
  • Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the pathology of asthma, applying research bronchoscopy  (with endobronchial biopsy and bronchoalveolar lavage) and sputum induction. He led the initial task forces which defined the use of these two techniques, thereby paving the way for standardised research approches that enabled in-depth descriptions of the roles of various inflammatory cells and their mediators. He developed an explant model, consisting of bronchial biopsies placed into tissue culture, that could be stimulated ex vivo with relevant triggers, applying as needed, novel agents not yet approved for in vivo use in humans volunteers. 

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Professor Tom Wilkinson MA, Cantab, MBBS, PhD, FRCP

Associate Dean Enterprise

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Doctor Yihua Wang

Associate Professor

Research interests

  • Cell Signalling in Disease
  • Epithelial-Mesenchymal Crosstalk

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Doctor Eleanor Seaby

Clinical Research Fellow

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Collaborating research institutes, centres and groups

Developmental Biology

The Developmental Biology research group's research spans basic processes in reproduction and early development and their relevance to postnatal diseases from cancer to osteoporosis.

Integrative Molecular Phenotyping Centre

Southampton’s unique in-depth expertise in multi-omic technologies, combined with access to patient cohorts from world-leading collaborative clinical and commercial partners, aims to transform precision medicine across the disease spectrum, from cancer immunology to respiratory conditions.

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