1H and 13C NMR spectra provide a wealth of structural information that is useful to synthetic chemists. Selection of the appropriate 1D and 2D NMR experiments can enable the connectivity and geometry of the molecule to be assigned.
Example spectra:
1H, 13C, dept135, Jmod (trans-ethylcrotonate)
HH COSY (trans-ethylcrotonate, strychnine, sucrose)
HH TOCSY (sucrose)
HMQC (trans-ethylcrotonate, strychnine, sucrose)
HMBC (trans-ethylcrotonate, strychnine, sucrose)
Technical Information:
Spectra are acquired using a high-resolution liquids dual-head probe (5 mm) that allows direct 1D and 2D 1H NMR, direct observation of 13C NMR with 1H decoupling and inverse 2D experiments such as HMQC and HMBC.
In addition, the probe includes a 2H lock channel and variable temperature capability. Pulsed field gradient coils (PFG) are utilised to suppress artefacts and accelerate acquisition times for the useful multi-dimensional experiments.
Contact us
Email: scas@soton.ac.uk
Tel: +44(0)23 8059 8028
Office hours: Monday - Friday 0900-1700