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Professor John Holloway

John Holloway

Professor John Holloway is Professor of Allergy and Respiratory Genetics within Medicine at the University of Southampton.

John Holloway graduated with a B.Sc. in Biochemistry from Otago University, New Zealand in 1992. He undertook research based at both the University of Southampton and the Malaghan Institute (Wellington, New Zealand) into the genetic basis of asthma graduating with a Ph.D. from Otago University in 1997. In 1997 Professor Holloway returned to Southampton and together with Professor Stephen Holgate continued his research into the genetic basis of allergies and asthma. He now heads the Respiratory Genetics Group, based in the Human Development and Health and Clinical and Experimental Sciences Schools. The Respiratory Genetics Group undertakes a number of research projects into the genetic basis of allergy, asthma and other respiratory diseases. Research highlights include the identification of the gene ADAM33 as an asthma susceptibility gene (Nature 2002; 418:426) as a result of a collaborative project with Genome Therapeutics Corporation (Waltham, MA, USA) and Schering-Plough. More recently his work has focused on the genetic and epigenetic basis for the role of early life in determining susceptibility to these conditions.

Professor Holloway was appointed to a personal chair in the Faculty of Medicine in 2011. As well as his on-going research, he contributes to Clinical Pharmacology and Molecular Cell Biology teaching as part of the Bachelor of Medicine program.

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