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The University of Southampton
Observational Study Examining Osteoporosis

OStEO is a study investigating bone fracture and osteoporosis. We are inviting patients who have had a hip fracture and a hip replacement ad University Hospital Southampton to be involved in our study.

Participants are being asked for four main contributions

  1. Firstly, for permission to test the bone removed as part of their hip operation.
  2. To answer questions and for permission to look at their medical notes for information.
  3. For a blood sample to be taken.
  4. If possible, to return to the hospital after 1 month for a bone density scan (a DEXA and pQCT scan)

For more information on what is involved the patient information sheet (given at the hospital and available in the right hand banner). Additionally, the Frequently Asked Questions, FAQ section of this website aims to help answer your queries. If your question still can't be answered, please contact our researchers.

What happens to the donated bone?

The bone tissue that is removed as part of the hip replacement operation is to be tested at the University of Southampton. Testing will involve mechanical testing and imaging of the bone with the aim to discover more about the changes with osteoporosis and how they lead to bone fracture. Specifically a novel 'Reference Point Indentation' device will investigate new techniques for diagnosing osteoporosis.

For more information about the testing methods, please look at our 'What is Involved for the Bone Sample' page or view our results so far.

Participant Involvement

Complete questionaires

Give a blood sample

Assessment session (scans)

Permission to:

Test bone from hip surgery

Access medical records

Contact GP 

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