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Biological Sciences



Geoff Frampton: Evidence-based health technology and environmental research

Health technology assessment (HTA) research

I have been involved in a wide range of health technology assessment projects, some of which have involved appraising company submissions as part of the NICE Technology Appraisals process and have included economic evaluations to assess cost-effectiveness. For relevant publications and reports please see the left-hand menu. If you would like further information about any of these topics, or if you have an interest in possible collaborative work with SHTAC in any of these topic areas, or in relation to the methods of evidence synthesis, please feel free to contact me.

Complex interventions

  • Educational interventions for preventing catheter-related bloodstream infections in critical care (systematic map + systematic review)
  • Effectiveness of long-term weight management regimes (systematic review)
  • Interventions for encouraging sexual behaviours intended to prevent cervical cancer (Cochrane review)
  • Behavioural interventions for preventing sexually transmitted infections in young people (systematic map + systematic review)
  • Educational interventions for type 2 diabetes (systematic review)
  • Educational interventions to improve quality of life in people with chronic skin conditions (systematic review)


Diagnostic test accuracy assessments

  • Blood tests for diagnosting pre-eclampsia (systematic review and appraisal of company submissions)
  • Fundus autofluorescence imaging for diagnosing retinal conditions (systematic review)


Effectiveness of surgical interventions

  • Surgery for weight loss in adults (Cochrane review)
  • Second-eye cataract surgery (systematic review)


Effectiveness of drugs

  • Drugs for chronic hepatitis B and chronic hepatitis C (systematic reviews and appraisals of company submissions)
  • Drugs for asthma (systematic reviews and appraisals of company submissions)
  • Drugs for chronic myeloid leukaemia (appraisal of company submission)
  • Sotalol for preventing atrial fibrillation after coronary artery bypass graft surgery (appraisal of company submission)
  • Aripiprazole for schizophrenia (appraisal of company submission)
  • Recombinant growth hormone for growth disorders in children (systematic review)


Effectiveness of devices

  • Depth of anaesthesia monitoring during surgery (systematic review)


Health services research

  • Impacts of extended roles of allied health professionals (systematic review)