Drug enhances immune system to kill cancer cells
Scientists in the Faculty of Medicine, including those based in the Centre for Cancer Immunology, have discovered added benefits from using a drug called Selinexor to treat cancer.
Harnessing the power of nature to help improve anti-cancer therapy
Centre researchers have found a way to enhance the natural ability of therapeutic antibodies to attack blood cancer cells using part of the human immune system known as the complement cascade, opening the way for a potential new class of treatments.
Centre scientists discover a fundamental feature of aggressive lymphomas
A study led by a group of cancer experts including researchers from the Centre for Cancer Immunology has revealed a new fundamental feature of aggressive B-cell lymphomas which could open the door to further research into early detection and treatment of the disease.
International project provides definitive data on how key cancer drugs work
Scientists in the Centre for Cancer Immunology and Cancer Sciences at the University of Southampton, have provided new insight into how two important antibody drugs work and why they sometimes fail in some patients.
Bigger may not always be better: density not size governs receptor activation on immune cells
Novel insights into how an important class of immune receptors called tumour necrosis factor receptors (TNFR) are activated.
New trial into COVID-19 vaccine response in lymphoid cancer patients
A scientist based at the Centre for Cancer Immunology is leading a new observational trial, evaluating immune responses in patients with lymphoid cancers to COVID-19 vaccines.
Southampton scientists make breakthrough that could help patients with mesothelioma survive longer
Scientists based at the Centre for Cancer Immunology have made a breakthrough with immunotherapy that could help patients with a hard-to-treat cancer caused by asbestos.
Intensive combination chemotherapy and immunotherapy can improve survival for some patients with rare blood cancer
An international trial, run in the UK by researchers at the CRUK Southampton Clinical Trials Unit (SCTU) at the Centre for Cancer Immunology, has found that an intensive combination of chemotherapy and immunotherapy can dramatically improve survival for some patients with a rare blood cancer that typically have a very poor outlook.
Understanding how to improve antibodies targeting OX40 for the treatment of cancer
Understanding how to improve antibodies targeting OX40 for the treatment of cancer
£10 million research collaboration to detect lung cancer earlier
Professor Peter Johnson of the Centre for Cancer Immunology is to lead a ground-breaking project, which will explore new ways to diagnose lung cancer earlier and save lives.