Research project

R Brown - Factory in Fumehood

Research groups:

Organic Chemistry, Synthesis, Catalysis
Lead researcher:

Professor Richard Brown
Other researchers:

Professor David Harrowven
Research funder:

EPSRC
Status:

Not active

Staff

Lead researcher

Professor Richard Brown

Professor of Organic Chemistry

Connect with Richard

Email: R.C.Brown@soton.ac.uk

Other researchers

Professor David Harrowven

Professor of Chemistry

Connect with David

Email: dch2@soton.ac.uk

Collaborating research institutes, centres and groups

Organic Chemistry, Synthesis, Catalysis

We develop environmentally sustainable approaches to chemical manufacture that minimise chemical waste, improve product velocity and reduce the need to isolate intermediates.

Research outputs

A flow electrochemistry-enabled synthesis of 2-substituted N-(methyl-d)piperidines

Azzam A.M. Hadedi, Stuart Sawyer, Stuart J. Elliott, Robert A Green, Daniel J. O’leary, Richard C.D. Brown & Lynda J. Brown, 2022, Journal of Labelled Compounds and Radiopharmaceuticals, 65(14), 361-368

DOI: 10.1002/jlcr.4006

Type: article

Wavelength dependent photoextrusion and tandem photoextrusion reactions of ninhydrin bis-acetals for the synthesis of 8-ring lactones, benzocyclobutenes and orthoanhydrides

David C. Harrowven, Wei Sun, Surajit Kayal, William Raimbach, Xue-Zhong Sun, Mark Light, Magnus W.D. Hanson-Heine & Michael W George, 2021, ChemComm

DOI: 10.1039/D1CC06800H

Type: article

New Approaches to Ondansetron and Alosetron Inspire a Versatile, Flow Photochemical Method for Indole Synthesis

Wei Sun, William Raimbach, Luke D. Elliott, Kevin I. Booker-Milburn & David C. Harrowven, 2021, ChemComm, 58(3), 383-386

DOI: 10.1039/D1CC05700F

Type: article

A new mode of cyclobutenedione ring opening for the synthesis of 2-oxobut-3-enamides and tetrasubstituted furans

Ryan Bennett, Wei Sun, Dharyl Charles Wilson, Mark Light & David C. Harrowven, 2021, ChemComm, 57(46), 5694-5697

DOI: 10.1039/D1CC02097H

Type: article

A photochemical ring expansion of 6- to 8-membered nitrogen heterocycles by [1,3]-sigmatropic rearrangement

Morgan A. Manning, Wei Sun, Mark Light & David C. Harrowven, 2021, ChemComm, 57(37), 4556-4559

DOI: 10.1039/D1CC00393C

Type: article