Research project

Graham Burdge: BBSRC: How does polyunsaturated fatty acid biosynthesis regulate T lymphocyte function?

Research groups:

Plants and Food Security
Other researchers:

Professor Philip Calder,

Professor Karen Lillycrop
Research funder:

Biotechnology & Biological Sciences Research Council
Status:

Not active

Staff

Other researchers

Professor Philip Calder

Head of School

Connect with Philip

Email: P.C.Calder@soton.ac.uk

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

Epigenetics
Human Disease

Connect with Karen

Email: K.A.Lillycrop@soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Exogenous tetracosahexaenoic acid modifies the fatty acid composition of human primary T lymphocytes and Jurkat T cell leukemia cells contingent on cell type

Nicola A. Irvine, Annette L. West, Johanna Von Gerichten, Elizabeth A. Miles, Karen A. Lillycrop, Philip C. Calder, Barbara A. Fielding & Graham Burdge, 2023, Lipids, 58(4), 185-196

DOI: 10.1002/lipd.12372

Type: article

Fatty acid composition and metabolic partitioning of α-linolenic acid are contingent on life stage in human CD3+ T lymphocytes

Annette Lucy West, Johanna von Gerichten, Nicola Alice Irvine, Elizabeth Miles, Karen Lillycrop, Philip Calder, Barbara Fielding & Graham Burdge, 2022, Frontiers in Immunology, 1-13

DOI: 10.3389/fimmu.2022.1079642

Type: article

The partitioning of newly assimilated linoleic and α‐linolenic acids between synthesis of longer-chain polyunsaturated fatty acids and hydroxyoctadecaenoic acids is a putative branch point in T cell essential fatty acid metabolism

Johanna Von Gerichten, Annette West, Nicola Irvine, Elizabeth Miles, Philip Calder, Karen Lillycrop, Barbara Fielding & Graham Burdge, 2021, Frontiers in Immunology, 12

DOI: 10.3389/fimmu.2021.740749

Type: article

How does polyunsaturated fatty acid biosynthesis regulate T lymphocyte function?

Barbara Fielding, Philip Calder, Nicola Irvine, Elizabeth Miles, Karen Lillycrop, Johanna von Gerichten & Graham Burdge, 2019, Nutrition Bulletin, 44(4), 350-355

DOI: 10.1111/nbu.12404

Type: article