Research project

Mechanisms of long-range retrograde signal propogation - Deinhardt - BBSRC

Research groups:

Neuroscience
Lead researcher:

Professor Katrin Deinhardt
Research funder:

Biotechnology & Biological Sciences Research Council
Status:

Not active

Staff

Lead researcher

Professor Katrin Deinhardt

Professor

Research interests

Short- and long-range neurotrophin signalling and its role in morphological plasticity
Early neuronal dysfunction in disturbed proteostasis
Cellular mechanisms that underlie tau propagation across neurons

Connect with Katrin

Email: K.Deinhardt@soton.ac.uk

Collaborating research institutes, centres and groups

Neuroscience

We work on national and global priorities of health and well-being, underpinning research in neuroscience, and age-related neurodegenerative diseases, including Alzheimer’s.

Research outputs

A 5′ UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation

Connor Maltby, James Schofield, Steven Houghton, Ita O'Kelly, Mariana Vargas-Caballero, Katrin Deinhardt & Mark Coldwell, 2020, Nucleic Acids Research, 48(17), 9822-9839

DOI: 10.1093/nar/gkaa699

Type: article

Co-culture of murine neurons using a microfluidic device for the study of Tau misfolding propagation

Grace Hallinan, Dianne Lopez, Mariana Vargas-caballero, Jonathan West & Katrin Deinhardt, 2020, Bio-protocol, 10(16)

DOI: 10.21769/BioProtoc.3718

Type: article

Quantitative and correlative extreme ultraviolet coherent imaging of mouse hippocampal neurons at high resolution

Peter Baksh, Michal Odstrčil, Magdalena Miszczak, Charles Pooley, Richard Chapman, Adam Wyatt, Emma Springate, John Chad, Katrin Deinhardt, Jeremy G. Frey & William Brocklesby, 2020, Science Advances, 6(18)

DOI: 10.1126/sciadv.aaz3025

Type: article

Tau misfolding efficiently propagates between individual intact hippocampal neurons

Grace Hallinan, Mariana Vargas-Caballero, Jonathan West & Katrin Deinhardt, 2019, The Journal of Neuroscience, 39(48), 9623-9632

DOI: 10.1523/JNEUROSCI.1590-19.2019

Type: article

Proteomic approaches to dissect neuronal signalling pathways

Heather Bowling, Shruti Nayak & Katrin Deinhardt, 2019

DOI: 10.1007/978-3-030-15950-4_27

Type: bookChapter