Professor Diana Eccles MB ChB, MD, FRCP
Professor of Cancer Genetics, Director of the University of Southampton Clinical Trials Unit
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Professor Diana Eccles is Professor of Cancer Genetics within Medicine at the University of Southampton.
Professor Eccles has been Chair of Cancer Genetics since 2004. She graduated from Manchester University on 1983 and has trained in Manchester, Edinburgh and Southampton. After training in general medicine, then specialist training in adult oncology she worked on the molecular genetics of ovarian cancer in the MRC Human Genetics Unit in Edinburgh to gain her MD in 1992. She then moved to Southampton to a research post in Genetic Epidemiology simultaneously training in Clinical Genetics and when appointed to a consultant post in Southampton in 1995 she set up one of the first NHS funded Cancer Genetics Services in the UK within the Wessex Clinical Genetics Service.
Professor Eccles is the Chief Investigator for a large national cohort study (the Prospective study of Outcomes in Sporadic versus Hereditary breast cancer. This study has recruited over 3000 women with breast cancer diagnosed before 41 years of age and provides material for studies investigating the role of inherited genetic mutation in breast cancer risk and prognosis. She is PI for a number of other clinical studies that broadly aim to improve diagnosis or management of genetic predisposition to cancer and incorporates cancer prevention studies.
In addition to research and teaching, Professor Eccles is the Director of the University of Southampton Clinical Trials Unit which is supported by Cancer Research UK and NIHR core grants to design and run large multicenter practice changing clinical trials, particularly studies to improve drug treatments. She continues to work as an NHS consultant in clinical cancer genetics which encompasses diagnosis and management of many different genetic conditions that predispose to tumour development in families.
MB ChB, Medicine and Surgery, Manchester University (1983)
MRCP, Royal College of Physicians Edinburgh (1986)
MD, Molecular Genetics of Ovarian Cancer, Manchester University (1992)
Lecturer in Medical Oncology 1986-1989
Clinical Research Fellow in MRC Human Genetics Unit Edinburgh 1989-1992
Clinical Research Fellow in Cancer Genetics Epidemiology Research Group and Honorary Senior Registrar in Clinical Genetics, Southampton 1992-1994
Consultant in Clinical Genetics (Cancer specialization) and Honorary Senior Lecturer in Cancer Genetics, Southampton 1995-2004
Professor of Cancer Genetics and Honorary Consultant in Clinical Genetics, Southampton 2004-present
Director of University of Southampton Clinical Trials Unit December 2009-present