The University of Southampton
Medicine

Professor Diana Eccles MB ChB, MD, FRCP

Professor of Cancer Genetics, Head of Cancer Sciences Academic Unit

Professor Diana Eccles's photo
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Professor Diana Eccles is Professor of Cancer Genetics within Medicine at the University of Southampton.

Professor Eccles has been Chair of Cancer Genetics since 2004. She graduated from Manchester University on 1983 and has trained in Manchester, Edinburgh and Southampton. After training in general medicine, then specialist training in adult oncology she worked on the molecular genetics of ovarian cancer in the MRC Human Genetics Unit in Edinburgh to gain her MD in 1992. She then moved to Southampton to a research post in Genetic Epidemiology simultaneously training in Clinical Genetics and when appointed to a consultant post in Southampton in 1995 she set up one of the first NHS funded Cancer Genetics Services in the UK within the Wessex Clinical Genetics Service.

Professor Eccles is the Chief Investigator for a large national cohort study (the Prospective study of Outcomes in Sporadic versus Hereditary breast cancer). This study has recruited over 3000 women with breast cancer diagnosed before 41 years of age and provides material for studies investigating the role of inherited genetic mutation in breast cancer risk and prognosis. She is PI for a number of other clinical studies that broadly aim to improve diagnosis or management of genetic predisposition to cancer and incorporates cancer prevention studies.

Professor Eccles is the Head of the Cancer Sciences Academic Unit which incorporates the Southampton Cancer Research UK Centre, the Southampton Clinical Trials Unit and links closely through our clinical academics to Cancer Care at UHS (http://www.southampton.ac.uk/medicine/research/groups/cancer_sciences_research_group.page). She continues to work as an NHS consultant in clinical cancer genetics which encompasses diagnosis and management of many different genetic conditions that predispose to tumour development in families.

Qualifications

MB ChB, Medicine and Surgery, Manchester University (1983)
MRCP, Royal College of Physicians Edinburgh (1986)
MD, Molecular Genetics of Ovarian Cancer, Manchester University (1992)

Appointments held

Lecturer in Medical Oncology 1986-1989

Clinical Research Fellow in MRC Human Genetics Unit Edinburgh 1989-1992

Clinical Research Fellow in Cancer Genetics Epidemiology Research Group and Honorary Senior Registrar in Clinical Genetics, Southampton 1992-1994

Consultant in Clinical Genetics (Cancer specialization) and Honorary Senior Lecturer in Cancer Genetics, Southampton 1995-2004

Professor of Cancer Genetics and Honorary Consultant in Clinical Genetics, Southampton 2004-present

Director of University of Southampton Clinical Trials Unit December 2009-2014

Head of Cancer Sciences Academic Unit 2015-present

Research

Responsibilities

Publications

Teaching

Contact

Research interests

Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (acronym POSH). This National Cancer Research Network Portfolio study has recruited over 3000 women diagnosed with breast cancer at very young ages (before 41 years. Breast cancer diagnosed at these young ages comprises less than 10% of all breast cancers. Young age at diagnosis is associated with a lower chance of survival and this group is also enriched patients who carry genetic factors that predispose to breast cancer. Comprehensive clinical data and DNA samples for most recruits are available. Flagging in the national Medical Research Information Service database means that the patients taking part in the study can be tracked for twenty years following diagnosis. Mean and median follow up of the cohort is approaching 5 years and a variety of early outcome studies are now being completed including

The effect of high risk genes on survival: this project is exploring whether breast cancer caused by the high risk predisposition genes BRCA1 and BRCA2 respond differently to conventional treatments.

The effect of common genetic variants on breast cancer diagnosis and survival is being explored in a series of international collaborative experiments linking in closely with the bioinformatics research group.

Exploring the validity of available prognostic predictors in younger women with breast cancer as a project within the MSc Clinical Trials and Statistics course in Southampton.

In addition, linking in with researchers in qualitative medicine in the Faculty of Health Sciences, a Research for Patient Benefit project (funded by the NIHR) will use the POSH patient cohort and experience of the diagnosis and treatment of breast cancer in this age group to explore and improve approaches to information giving at diagnosis. A Decision Aid aimed specifically at younger women will be developed and piloted in preparation for a future randomised trial of its use.

Tumour tissue is being collected for all the cases and in collaboration with QMUL tissue micro arrays (TMAs) are assembled. Pathology and breast cancer radiological images are captured electronically using software developed in house by the Clinical Research Informatics Research Unit.

One of the most potent cancer predisposition syndromes known is the Li Fraumeni syndrome. This is caused by an inherited mutation in the very important gene TP53. An inherited fault in this gene greatly increases the risk of cancers but particularly early onset breast cancer. A new study (COPE) is aiming to determine the type and timing of the key molecular events in breast cancers arising in patients with a germline TP53 mutation.

Academic unit(s)

Cancer Sciences Academic Unit

Affiliate academic unit(s)

Cancer Sciences Research group

Postgraduate student supervision

Completed

1995-1998 Wendy Sotheran MD
2000-2004 Mohammed Al-Dahmesh PhD
2004-2008 Ellen Copson PhD
2006-2010 Victoria Hammond PhD
2008-2013 Ioannis Politopoulos PhD
2009-2014 Rosie Upstill-Goddard PhD

Current

2012-present Kate Packwood
2015-present Hayley McKenzie

University of Southampton

2015-present     Head of Cancer Sciences Academic Unit
2012-2014         Chair of the Faculty of Medicine Athena Swan Silver Self-Assessment Team

National and International responsibilities

2016-ongoing   Cancer Research UK Clinical Careers Committee
2014-ongoing   UK Genetic Testing Network – Genetic Test Evaluation Working Group
2015-ongoing   Genomics England Hereditary Cancer Genomics Clinical Interpretation Partnership
2015-2016         Research Council of Norway Scientific Advisory Board for Centres of Excellence Awards
2014-ongoing   Member of the Advisory Board Astra Zeneca PARP inhibitor trials
2012-ongoing   Member of the BCC Tissue Bank Tissue Access Committee (TAC)
2014-ongoing   Member of the NCRI Colorectal Clinical Studies Group
2014-ongoing   Member of the UK Cancer Prevention Studies Group
2012-2015         Academic Vice President of the Clinical Genetics Society
2011-2013         National Institute for Clinical Excellence Guideline Development Group responsible for developing the revised Management of Familial Breast Cancer Guideline CG164
2011-2015         MRC Clinical Research Training Fellows Scientific Review Board (Member)
2010-2014         Member of National Cancer Research Institute Breast Cancer Studies Group
2011-2014         Canadian Breast Cancer Foundation Scientific Advisory Board (Member)
2009-2014         Associate Editor of the Journal of Medical Genetics

 

 

 

Article(s)

  • Information requirements of young women with breast cancer treated with mastectomy or breast conserving surgery: a systematic review - Recio-Saucedo, Alejandra, Gerty, Sue, Foster, Claire, Eccles, Diana and Cutress, Ramsey I.
    Published:
    2016
    Publication:
    The Breast
    Volume:
    25
    Page Range:
    1-13
    doi:
    10.1016/j.breast.2015.11.001
    PMID:
    26801410
  • Genetic testing in a cohort of young patients with HER2 amplified breast cancer - Eccles, D.M., Li, N., Handwerker, R., Maishman, T., Copson, E.R., Durcan, L.T., Gerty, S.M., Jones, L., Evans, D.G., Haywood, L. and Campbell, I.
    Published:
    2015
    Publication:
    Annals of Oncology
    Page Range:
    1-20
  • Effect of BRCA mutations on metastatic relapse and cause-specific survival after radical treatment for localised prostate cancer - Castro, Elena, Goh, Chee, Leongamornlert, Daniel, Saunders, Ed, Tymrakiewicz, Malgorzata, Dadaev, Tokhir, Govindasami, Koveela, Guy, Michelle, Ellis, Steve, Frost, Debra, Bancroft, Elizabeth, Cole, Trevor, Tischkowitz, Marc, Kennedy, M. John, Eason, Jacqueline, Brewer, Carole, Evans, D. Gareth, Davidson, Rosemarie, Eccles, Diana, Porteous, Mary E., Douglas, Fiona, Adlard, Julian, Donaldson, Alan, Antoniou, Antonis C., Kote-Jarai, Zsofia, Easton, Douglas F., Olmos, David and Eeles, Rosalind
    Published:
    2015
    Publication:
    European Urology
    Volume:
    68, (2)
    Page Range:
    186-193
    doi:
    10.1016/j.eururo.2014.10.022
    PMID:
    25454609
  • BRCA1 and BRCA2 genetic testing – pitfalls and recommendations for managing variants of uncertain clinical significance - Eccles, D., Mitchell, G., Monteiro, A.N.A., Schmutzler, R., Couch, F.J., Spurdle, A.B. and Gómez-García, E.B.
    Published:
    2015
    Publication:
    Annals of Oncology
    Volume:
    26, (10)
    Page Range:
    2057-2065
    doi:
    10.1093/annonc/mdv278
    PMID:
    26153499
  • Family history and outcome of young patients with breast cancer in the UK (POSH study) - Eccles, B.K., Copson, E.R., Cutress, R., Maishman, T., Altman, D.G., Simmonds, P., Gerty, S., Durcan, L., Stanton, L. and Eccles, D.M.
    Published:
    2015
    Publication:
    British Journal of Surgery
    Volume:
    102, (8)
    Page Range:
    924-935
    doi:
    10.1002/bjs.9816
    PMID:
    25989914
  • Common genetic variation in cellular transport genes and epithelial ovarian cancer (EOC) risk - Agoulnik, Irina U., Chornokur, Ganna, Lin, Hui-Yi, Tyrer, Jonathan P., Lawrenson, Kate, Dennis, Joe, Amankwah, Ernest K., Qu, Xiaotao, Tsai, Ya-Yu, Jim, Heather S.L., Chen, Zhihua, Chen, Ann Y., Permuth-Wey, Jennifer, Aben, Katja K.H., Anton-Culver, Hoda, Antonenkova, Natalia, Bruinsma, Fiona, Bandera, Elisa V., Bean, Yukie T., Beckmann, Matthias W., Bisogna, Maria, Bjorge, Line, Bogdanova, Natalia, Brinton, Louise A., Brooks-Wilson, Angela, Bunker, Clareann H., Butzow, Ralf, Campbell, Ian G., Carty, Karen, Chang-Claude, Jenny, Cook, Linda S., Cramer, Daniel W., Cunningham, Julie M., Cybulski, Cezary, Dansonka-Mieszkowska, Agnieszka, du Bois, Andreas, Despierre, Evelyn, Dicks, Ed, Doherty, Jennifer A., Dörk, Thilo, Dürst, Matthias, Easton, Douglas F., Eccles, Diana M., Edwards, Robert P., Ekici, Arif B., Fasching, Peter A., Fridley, Brooke L., Gao, Yu-Tang, Gentry-Maharaj, Aleksandra, Giles, Graham G., Glasspool, Rosalind, Goodman, Marc T., Gronwald, Jacek, Harrington, Patricia, Harter, Philipp, Hein, Alexander, Heitz, Florian, Hildebrandt, Michelle A. T., Hillemanns, Peter, Hogdall, Claus K., Hogdall, Estrid, Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Ji, Bu-Tian, Karlan, Beth Y., Kelemen, Linda E., Kellar, Mellissa, Kiemeney, Lambertus A., Krakstad, Camilla, Kjaer, Susanne K., Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Le, Nhu D., Lee, Alice W., Lele, Shashi, Leminen, Arto, Lester, Jenny, Levine, Douglas A., Liang, Dong, Lim, Boon Kiong, Lissowska, Jolanta, Lu, Karen, Lubinski, Jan, Lundvall, Lene, Massuger, Leon F. A. G., Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R., McNeish, Iain, Menon, Usha, Milne, Roger L., Modugno, Francesmary, Moysich, Kirsten B., Ness, Roberta B., Nevanlinna, Heli, Eilber, Ursula, Odunsi, Kunle, Olson, Sara H., Orlow, Irene, Orsulic, Sandra, Weber, Rachel Palmieri, Paul, James, Pearce, Celeste L., Pejovic, Tanja, Pelttari, Liisa M., Pike, Malcolm C., Poole, Elizabeth M., Risch, Harvey A., Rosen, Barry, Rossing, Mary Anne, Rothstein, Joseph H., Rudolph, Anja, Runnebaum, Ingo B., Rzepecka, Iwona K., Salvesen, Helga B., Schernhammer, Eva, Schwaab, Ira, Shu, Xiao-Ou, Shvetsov, Yurii B., Siddiqui, Nadeem, Sieh, Weiva, Song, Honglin, Southey, Melissa C., Spiewankiewicz, Beata, Sucheston, Lara, Teo, Soo-Hwang, Terry, Kathryn L., Thompson, Pamela J., Thomsen, Lotte, Tangen, Ingvild L., Tworoger, Shelley S., van Altena, Anne M., Vierkant, Robert A., Vergote, Ignace, Walsh, Christine S., Wang-Gohrke, Shan, Wentzensen, Nicolas, Whittemore, Alice S., Wicklund, Kristine G., Wilkens, Lynne R., Wu, Anna H., Wu, Xifeng, Woo, Yin-Ling, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Hasmad, Hanis N., Berchuck, Andrew, Iversen, Edwin S., Schildkraut, Joellen M., Ramus, Susan J., Goode, Ellen L., Monteiro, Alvaro N. A., Gayther, Simon A., Narod, Steven A., Pharoah, Paul D. P., Sellers, Thomas A. and Phelan, Catherine M.
    Published:
    2015
    Publication:
    PLoS ONE
    Volume:
    10, (6)
    Page Range:
    e0128106-[17pp]
    doi:
    10.1371/journal.pone.0128106
    PMID:
    26091520
  • Polymorphism at 19q13.41 predicts breast cancer survival specifically after endocrine therapy - Khan, S., Fagerholm, R., Rafiq, S., Tapper, W., Aittomaki, K., Liu, J., Blomqvist, C., Eccles, D. and Nevanlinna, H.
    Published:
    2015
    Publication:
    Clinical Cancer Research
    Page Range:
    1-11
    doi:
    10.1158/1078-0432.CCR-15-0296
    PMID:
    25964295
  • Crowdsourcing the general public for large scale molecular pathology studies in cancer - Candido do Reis, Francisco J., Lynn, Stuart, Ali, H. Raza, Eccles, Diana, Hanby, Andrew, Provenzano, Elena, Caldas, Carlos, Howat, William J., McDuffus, Leigh-Anne, Liu, Bin, Daley, Frances, Coulson, Penny, Vyas, Rupesh J., Harris, Leslie M., Owens, Joanna M., Carton, Amy F.M., McQuillan, Janette P., Paterson, Andy M., Hirji, Zohra, Christie, Sarah K., Holmes, Amber R., Schmidt, Marjanka K., Garcia-Closas, Montserrat, Easton, Douglas F., Bolla, Manjeet K., Wang, Qin, Benitez, Javier, Milne, Roger L., Mannermaa, Arto, Couch, Fergus, Devilee, Peter, Tollenaar, Robert A.E.M., Seynaeve, Caroline, Cox, Angela, Cross, Simon S., Blows, Fiona M., Sanders, Joyce, de Groot, Renate, Figueroa, Jonine, Sherman, Mark, Hooning, Maartje, Brenner, Hermann, Holleczek, Bernd, Stegmaier, Christa, Lintott, Chris and Pharoah, Paul D.P.
    Published:
    2015
    Publication:
    EBioMedicine
    Page Range:
    1-22
    doi:
    10.1016/j.ebiom.2015.05.009
  • No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer - Hollestelle, Antoinette, van der Baan, Frederieke H., Berchuck, Andrew, Johnatty, Sharon E., Aben, Katja K., Agnarsson, Bjarni A., Aittomäki, Kristiina, Alducci, Elisa, Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Antoniou, Antonis C., Apicella, Carmel, Arndt, Volker, Arnold, Norbert, Arun, Banu K., Arver, Brita, Ashworth, Alan, Baglietto, Laura, Balleine, Rosemary, Bandera, Elisa V., Barrowdale, Daniel, Bean, Yukie T., Beckmann, Lars, Beckmann, Matthias W., Benitez, Javier, Berger, Andreas, Berger, Raanan, Beuselinck, Benoit, Bisogna, Maria, Bjorge, Line, Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Anders, Bojesen, Stig E., Bolla, Manjeet K., Bonanni, Bernardo, Brand, Judith S., Brauch, Hiltrud, Brenner, Hermann, Brinton, Louise, Brooks-Wilson, Angela, Bruinsma, Fiona, Brunet, Joan, Brüning, Thomas, Budzilowska, Agnieszka, Bunker, Clareann H., Burwinkel, Barbara, Butzow, Ralf, Buys, Saundra S., Caligo, Maria A., Campbell, Ian, Carter, Jonathan, Chang-Claude, Jenny, Chanock, Stephen J., Claes, Kathleen B.M., Collée, J. Margriet, Cook, Linda S., Couch, Fergus J., Cox, Angela, Cramer, Daniel, Cross, Simon S., Cunningham, Julie M., Cybulski, Cezary, Czene, Kamila, Damiola, Francesca, Dansonka-Mieszkowska, Agnieszka, Darabi, Hatef, de la Hoya, Miguel, deFazio, Anna, Dennis, Joseph, Devilee, Peter, Dicks, Ed M., Diez, Orland, Doherty, Jennifer A., Domchek, Susan M., Dorfling, Cecilia M., Dörk, Thilo, Silva, Isabel Dos Santos, du Bois, Andreas, Dumont, Martine, Dunning, Alison M., Duran, Mercedes, Easton, Douglas F., Eccles, Diana, Edwards, Robert P., Ehrencrona, Hans, Ejlertsen, Bent, Ekici, Arif B., Ellis, Steve D., Engel, Christoph, Eriksson, Mikael, Fasching, Peter A., Feliubadalo, Lidia, Figueroa, Jonine, Flesch-Janys, Dieter, Fletcher, Olivia, Fontaine, Annette, Fortuzzi, Stefano, Fostira, Florentia, Fridley, Brooke L., Friebel, Tara, Friedman, Eitan, Friel, Grace, Frost, Debra, Garber, Judy, García-Closas, Montserrat, Gayther, Simon A., Gentry-Maharaj, Aleksandra, Gerdes, Anne-Marie, Giles, Graham G., Glasspool, Rosalind, Glendon, Gord, Godwin, Andrew K., Goodman, Marc T., Gore, Martin, Greene, Mark H., Grip, Mervi, Gronwald, Jacek, Gschwantler Kaulich, Daphne, Guénel, Pascal, Guzman, Starr R., Haeberle, Lothar, Haiman, Christopher A., Hall, Per, Halverson, Sandra L., Hamann, Ute, Hansen, Thomas V.O., Harter, Philipp, Hartikainen, Jaana M., Healey, Sue, Hein, Alexander, Heitz, Florian, Henderson, Brian E., Herzog, Josef, T Hildebrandt, Michelle A., Høgdall, Claus K., Høgdall, Estrid, Hogervorst, Frans B.L., Hopper, John L., Humphreys, Keith, Huzarski, Tomasz, Imyanitov, Evgeny N., Isaacs, Claudine, Jakubowska, Anna, Janavicius, Ramunas, Jaworska, Katarzyna, Jensen, Allan, Jensen, Uffe Birk, Johnson, Nichola, Jukkola-Vuorinen, Arja, Kabisch, Maria, Karlan, Beth Y., Kataja, Vesa, Kauff, Noah, Kelemen, Linda E., Kerin, Michael J., Kiemeney, Lambertus A., Kjaer, Susanne K., Knight, Julia A., Knol-Bout, Jacoba P., Konstantopoulou, Irene, Kosma, Veli-Matti, Krakstad, Camilla, Kristensen, Vessela, Kuchenbaecker, Karoline B., Kupryjanczyk, Jolanta, Laitman, Yael, Lambrechts, Diether, Lambrechts, Sandrina, Larson, Melissa C., Lasa, Adriana, Laurent-Puig, Pierre, Lazaro, Conxi, Le, Nhu D., Le Marchand, Loic, Leminen, Arto, Lester, Jenny, Levine, Douglas A., Li, Jingmei, Liang, Dong, Lindblom, Annika, Lindor, Noralane, Lissowska, Jolanta, Long, Jirong, Lu, Karen H., Lubinski, Jan, Lundvall, Lene, Lurie, Galina, Mai, Phuong L., Mannermaa, Arto, Margolin, Sara, Mariette, Frederique, Marme, Frederik, Martens, John W.M., Massuger, Leon F.A.G., Maugard, Christine, Mazoyer, Sylvie, McGuffog, Lesley, McGuire, Valerie, McLean, Catriona, McNeish, Iain, Meindl, Alfons, Menegaux, Florence, Menéndez, Primitiva, Menkiszak, Janusz, Menon, Usha, Mensenkamp, Arjen R., Miller, Nicola, Milne, Roger L., Modugno, Francesmary, Montagna, Marco, Moysich, Kirsten B., Müller, Heiko, Mulligan, Anna Marie, Muranen, Taru A., Narod, Steven A., Nathanson, Katherine L., Ness, Roberta B., Neuhausen, Susan L., Nevanlinna, Heli, Neven, Patrick, Nielsen, Finn C., Nielsen, Sune F., Nordestgaard, Børge G., Nussbaum, Robert L., Odunsi, Kunle, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I., Olson, Janet E., Olson, Sara H., Oosterwijk, Jan C., Orlow, Irene, Orr, Nick, Orsulic, Sandra, Osorio, Ana, Ottini, Laura, Paul, James, Pearce, Celeste L., Pedersen, Inge Sokilde, Peissel, Bernard, Pejovic, Tanja, Pelttari, Liisa M., Perkins, Jo, Permuth-Wey, Jenny, Peterlongo, Paolo, Peto, Julian, Phelan, Catherine M., Phillips, Kelly-Anne, Piedmonte, Marion, Pike, Malcolm C., Platte, Radka, Plisiecka-Halasa, Joanna, Poole, Elizabeth M., Poppe, Bruce, Pylkäs, Katri, Radice, Paolo, Ramus, Susan J., Rebbeck, Timothy R., Reed, Malcolm W.R., Rennert, Gad, Risch, Harvey A., Robson, Mark, Rodriguez, Gustavo C., Romero, Atocha, Rossing, Mary Anne, Rothstein, Joseph H., Rudolph, Anja, Runnebaum, Ingo, Salani, Ritu, Salvesen, Helga B., Sawyer, Elinor J., Schildkraut, Joellen M., Schmidt, Marjanka K., Schmutzler, Rita K., Schneeweiss, Andreas, Schoemaker, Minouk J., Schrauder, Michael G., Schumacher, Fredrick, Schwaab, Ira, Scuvera, Giulietta, Sellers, Thomas A., Severi, Gianluca, Seynaeve, Caroline M., Shah, Mitul, Shrubsole, Martha, Siddiqui, Nadeem, Sieh, Weiva, Simard, Jacques, Singer, Christian F., Sinilnikova, Olga M., Smeets, Dominiek, Sohn, Christof, Soller, Maria, Song, Honglin, Soucy, Penny, Southey, Melissa C., Stegmaier, Christa, Stoppa-Lyonnet, Dominique, Sucheston, Lara, Swerdlow, Anthony, Tangen, Ingvild L., Tea, Muy-Kheng, Teixeira, Manuel R., Terry, Kathryn L., Terry, Mary Beth, Thomassen, Mads, Thompson, Pamela J., Tihomirova, Laima, Tischkowitz, Marc, Toland, Amanda Ewart, Tollenaar, Rob A.E.M., Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Tsimiklis, Helen, Tung, Nadine, Tworoger, Shelley S., Tyrer, Jonathan P., Vachon, Celine M., Van 't Veer, Laura J., van Altena, Anne M., Van Asperen, C.J., van den Berg, David, van den Ouweland, Ans M.W., van Doorn, Helena C., Van Nieuwenhuysen, Els, van Rensburg, Elizabeth J., Vergote, Ignace, Verhoef, Senno, Vierkant, Robert A., Vijai, Joseph, Vitonis, Allison F., von Wachenfeldt, Anna, Walsh, Christine, Wang, Qin, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Weischer, Maren, Weitzel, Jeffrey N., Weltens, Caroline, Wentzensen, Nicolas, Whittemore, Alice S., Wilkens, Lynne R., Winqvist, Robert, Wu, Anna H., Wu, Xifeng, Yang, Hannah P., Zaffaroni, Daniela, Pilar Zamora, M., Zheng, Wei, Ziogas, Argyrios, Chenevix-Trench, Georgia, Pharoah, Paul D.P., Rookus, Matti A., Hooning, Maartje J. and Goode, Ellen L.
    Published:
    2015
    Publication:
    Gynecologic Oncology
    doi:
    10.1016/j.ygyno.2015.04.034
    PMID:
    25940428
  • Prediction of breast cancer risk based on profiling with common genetic variants - Mavaddat, N., Pharoah, P.D.P., Michailidou, K., Tyrer, J., Brook, M.N., Bolla, M.K., Wang, Q., Dennis, J., Dunning, A.M., Shah, M., Luben, R., Brown, J., Bojesen, S.E., Nordestgaard, B.G., Nielsen, S.F., Flyger, H., Czene, K., Darabi, H., Eriksson, M., Peto, J., dos-Santos-Silva, I., Dudbridge, F., Johnson, N., Schmidt, M. K., Broeks, A., Verhoef, S., Rutgers, E.J., Swerdlow, A., Ashworth, A., Orr, N., Schoemaker, M.J., Figueroa, J., Chanock, S.J., Brinton, L., Lissowska, J., Couch, F.J., Olson, J.E., Vachon, C., Pankratz, V.S., Lambrechts, D., Wildiers, H., Van Ongeval, C., van Limbergen, E., Kristensen, V., Grenaker Alnaes, G., Nord, S., Borresen-Dale, A.-L., Nevanlinna, H., Muranen, T.A., Aittomaki, K., Blomqvist, C., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Fasching, P.A., Haeberle, L., Ekici, A.B., Beckmann, M.W., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Trentham-Dietz, A., Newcomb, P., Titus, L., Egan, K.M., Hunter, D.J., Lindstrom, S., Tamimi, R.M., Kraft, P., Rahman, N., Turnbull, C., Renwick, A., Seal, S., Li, J., Liu, J., Humphreys, K., Benitez, J., Pilar Zamora, M., Arias Perez, J.I., Menendez, P., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Bogdanova, N.V., Antonenkova, N.N., Dork, T., Anton-Culver, H., Neuhausen, S.L., Ziogas, A., Bernstein, L., Devilee, P., Tollenaar, R.A.E.M., Seynaeve, C., van Asperen, C.J., Cox, A., Cross, S.S., Reed, M.W.R., Khusnutdinova, E., Bermisheva, M., Prokofyeva, D., Takhirova, Z., Meindl, A., Schmutzler, R.K., Sutter, C., Yang, R., Schurmann, P., Bremer, M., Christiansen, H., Park-Simon, T.-W., Hillemanns, P., Guenel, P., Truong, T., Menegaux, F., Sanchez, M., Radice, P., Peterlongo, P., Manoukian, S., Pensotti, V., Hopper, J.L., Tsimiklis, H., Apicella, C., Southey, M.C., Brauch, H., Bruning, T., Ko, Y.-D., Sigurdson, A. J., Doody, M. M., Hamann, U., Torres, D., Ulmer, H.-U., Forsti, A., Sawyer, E. J., Tomlinson, I., Kerin, M.J., Miller, N., Andrulis, I.L., Knight, J.A., Glendon, G., Marie Mulligan, A., Chenevix-Trench, G., Balleine, R., Giles, G.G., Milne, R.L., McLean, C., Lindblom, A., Margolin, S., Haiman, C.A., Henderson, B.E., Schumacher, F., Le Marchand, L., Eilber, U., Wang-Gohrke, S., Hooning, M. J., Hollestelle, A., van den Ouweland, A.M.W., Koppert, L.B., Carpenter, J., Clarke, C., Scott, R., Mannermaa, A., Kataja, V., Kosma, V.-M., Hartikainen, J.M., Brenner, H., Arndt, V., Stegmaier, C., Karina Dieffenbach, A., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Offit, K., Vijai, J., Robson, M., Rau-Murthy, R., Dwek, M., Swann, R., Annie Perkins, K., Goldberg, M.S., Labreche, F., Dumont, M., Eccles, D.M., Tapper, W.J., Rafiq, S., John, E. M., Whittemore, A. S., Slager, S., Yannoukakos, D., Toland, A. E., Yao, S., Zheng, W., Halverson, S. L., Gonzalez-Neira, A., Pita, G., Rosario Alonso, M., Alvarez, N., Herrero, D., Tessier, D.C., Vincent, D., Bacot, F., Luccarini, C., Baynes, C., Ahmed, S., Maranian, M., Healey, C.S., Simard, J., Hall, P., Easton, D. F. and Garcia-Closas, M.
    Published:
    2015
    Publication:
    JNCI Journal of the National Cancer Institute
    Volume:
    107, (5)
    Page Range:
    1-15
    doi:
    10.1093/jnci/djv036
    PMID:
    25855707
  • An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers - Blein, Sophie, Bardel, Claire, Danjean, Vincent, McGuffog, Lesley, Healey, Sue, Barrowdale, Daniel, Lee, Andrew, Dennis, Joe, Kuchenbaecker, Karoline B., Soucy, Penny, Terry, Mary Beth, Chung, Wendy K., Goldgar, David E., Buys, Saundra S., Janavicius, Ramunas, Tihomirova, Laima, Tung, Nadine, Dorfling, Cecilia M., van Rensburg, Elizabeth J., Neuhausen, Susan L., Ding, Yuan Chun, Gerdes, Anne-Marie, Ejlertsen, Bent, Nielsen, Finn C, Hansen, Thomas VO, Osorio, Ana, Benitez, Javier, Conejero, Raquel Andrés, Segota, Ena, Weitzel, Jeffrey N, Thelander, Margo, Peterlongo, Paolo, Radice, Paolo, Pensotti, Valeria, Dolcetti, Riccardo, Bonanni, Bernardo, Peissel, Bernard, Zaffaroni, Daniela, Scuvera, Giulietta, Manoukian, Siranoush, Varesco, Liliana, Capone, Gabriele L., Papi, Laura, Ottini, Laura, Yannoukakos, Drakoulis, Konstantopoulou, Irene, Garber, Judy, Hamann, Ute, Donaldson, Alan, Brady, Angela, Brewer, Carole, Foo, Claire, Evans, D. Gareth, Frost, Debra, Eccles, Diana, Douglas, Fiona, Cook, Jackie, Adlard, Julian, Barwell, Julian, Walker, Lisa, Izatt, Louise, Side, Lucy E., Kennedy, M. John, Tischkowitz, Marc, Rogers, Mark T., Porteous, Mary E., Morrison, Patrick J., Platte, Radka, Eeles, Ros, Davidson, Rosemarie, Hodgson, Shirley, Cole, Trevor, Godwin, Andrew K., Isaacs, Claudine, Claes, Kathleen, De Leeneer, Kim, Meindl, Alfons, Gehrig, Andrea, Wappenschmidt, Barbara, Sutter, Christian, Engel, Christoph, Niederacher, Dieter, Steinemann, Doris, Plendl, Hansjoerg, Kast, Karin, Rhiem, Kerstin, Ditsch, Nina, Arnold, Norbert, Varon-Mateeva, Raymonda, Schmutzler, Rita K., Preisler-Adams, Sabine, Markov, Nadja Bogdanova, Wang-Gohrke, Shan, de Pauw, Antoine, Lefol, Cédrick, Lasset, Christine, Leroux, Dominique, Rouleau, Etienne, Damiola, Francesca, Dreyfus, Hélène, Barjhoux, Laure, Golmard, Lisa, Uhrhammer, Nancy, Bonadona, Valérie, Sornin, Valérie, Bignon, Yves-Jean, Carter, Jonathan, Van Le, Linda, Piedmonte, Marion, DiSilvestro, Paul A., de la Hoya, Miguel, Caldes, Trinidad, Nevanlinna, Heli, Aittomäki, Kristiina, Jager, Agnes, van den Ouweland, Ans M.W., Kets, Carolien M., Aalfs, Cora M., van Leeuwen, Flora E., Hogervorst, Frans B.L., Meijers-Heijboer, Hanne E.J., Oosterwijk, Jan C., van Roozendaal, Kees E.P., Rookus, Matti A., Devilee, Peter, van der Luijt, Rob B., Olah, Edith, Diez, Orland, Teulé, Alex, Lazaro, Conxi, Blanco, Ignacio, Del Valle, Jesús, Jakubowska, Anna, Sukiennicki, Grzegorz, Gronwald, Jacek, Lubinski, Jan, Durda, Katarzyna, Jaworska-Bieniek, Katarzyna, Agnarsson, Bjarni A., Maugard, Christine, Amadori, Alberto, Montagna, Marco, Teixeira, Manuel R., Spurdle, Amanda B., Foulkes, William, Olswold, Curtis, Lindor, Noralane M., Pankratz, Vernon S., Szabo, Csilla I, Lincoln, Anne, Jacobs, Lauren, Corines, Marina, Robson, Mark, Vijai, Joseph, Berger, Andreas, Fink-Retter, Anneliese, Singer, Christian F., Rappaport, Christine, Kaulich, Daphne Geschwantler, Pfeiler, Georg, Tea, Muy-Kheng, Greene, Mark H., Mai, Phuong L., Rennert, Gad, Imyanitov, Evgeny N., Mulligan, Anna Marie, Glendon, Gord, Andrulis, Irene L., Tchatchou, Sandrine, Toland, Amanda Ewart, Pedersen, Inge Sokilde, Thomassen, Mads, Kruse, Torben A., Jensen, Uffe Birk, Caligo, Maria A., Friedman, Eitan, Zidan, Jamal, Laitman, Yael, Lindblom, Annika, Melin, Beatrice, Arver, Brita, Loman, Niklas, Rosenquist, Richard, Olopade, Olufunmilayo I., Nussbaum, Robert L., Ramus, Susan J., Nathanson, Katherine L., Domchek, Susan M., Rebbeck, Timothy R., Arun, Banu K., Mitchell, Gillian, Karlan, Beth Y., Lester, Jenny, Orsulic, Sandra, Stoppa-Lyonnet, Dominique, Thomas, Gilles, Simard, Jacques, Couch, Fergus J., Offit, Kenneth, Easton, Douglas F., Chenevix-Trench, Georgia, Antoniou, Antonis C., Mazoyer, Sylvie, Phelan, Catherine M., Sinilnikova, Olga M. and Cox, David G.
    Published:
    2015
    Publication:
    Breast Cancer Research
    Volume:
    17, (1)
    Page Range:
    1-15
    doi:
    10.1186/s13058-015-0567-2
    PMID:
    25925750
  • Common germline polymorphisms associated with breast cancer-specific survival - Pirie, Ailith, Guo, Qi, Kraft, Peter, Canisius, Sander, Eccles, Diana M., Rahman, Nazneen, Nevanlinna, Heli, Chen, Constance, Khan, Sofia, Tyrer, Jonathan, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Michailidou, Kyriaki, Lush, Michael, Dunning, Alison M., Shah, Mitul, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Lambrechts, Dieter, Weltens, Caroline, Leunen, Karin, van Ongeval, Chantal, Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Blomqvist, Carl, Aittomäki, Kristiina, Fagerholm, Rainer, Muranen, Taru A., Olsen, Janet E., Hallberg, Emily, Vachon, Celine, Knight, Julia A., Glendon, Gord, Mulligan, Anna Marie, Broeks, Annegien, Cornelissen, Sten, Haiman, Christopher A., Henderson, Brian E., Schumacher, Frederick, Le Marchand, Loic, Hopper, John L., Tsimiklis, Helen, Apicella, Carmel, Southey, Melissa C., Cross, Simon S., Reed, Malcolm W.R., Giles, Graham G., Milne, Roger L., McLean, Catriona, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Hooning, Maartje J, Hollestelle, Antoinette, Martens, John WM, van den Ouweland, Ans MW, Marme, Federick, Schneeweiss, Andreas, Yang, Rongxi, Burwinkel, Barbara, Figueroa, Jonine, Chanock, Stephen J., Lissowska, Jolanta, Sawyer, Elinor J., Tomlinson, Ian, Kerin, Michael J., Miller, Nicola, Brenner, Hermann, Butterbach, Katja, Holleczek, Bernd, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Li, Jingmei, Brand, Judith S., Humphreys, Keith, Devilee, Peter, Tollenaar, Robert A.E.M., Seynaeve, Caroline, Radice, Paolo, Peterlongo, Paolo, Manoukian, Siranoush, Ficarazzi, Filomena, Beckmann, Matthias W, Hein, Alexander, Ekici, Arif B, Balleine, Rosemary, Phillips, Kelly-Anne, Benitez, Javier, Zamora, M Pilar, Perez, Jose Ignacio Arias, Menéndez, Primitiva, Jakubowska, Anna, Lubinski, Jan, Gronwald, Jacek, Durda, Katarzyna, Hamann, Ute, Kabisch, Maria, Ulmer, Hans Ulrich, Rüdiger, Thomas, Margolin, Sara, Kristensen, Vessela, Nord, Siljie, Evans, D Gareth, Abraham, Jean, Earl, Helena, Poole, Christopher J., Hiller, Louise, Dunn, Janet A., Bowden, Sarah, Yang, Rose, Campa, Daniele, Diver, W. Ryan, Gapstur, Susan M., Gaudet, Mia M, Hankinson, Susan, Hoover, Robert N., Hüsing, Anika, Kaaks, Rudolf, Machiela, Mitchell J., Willett, Walter, Barrdahl, Myrto, Canzian, Federico, Chin, Suet-Feung, Caldas, Carlos, Hunter, David J., Lindstrom, Sara, Garcia-Closas, Montserrat, Couch, Fergus J., Chenevix-Trench, Georgia, Mannermaa, Arto, Andrulis, Irene L., Hall, Per, Chang-Claude, Jenny, Easton, Douglas F., Bojesen, Stig E., Cox, Angela, Fasching, Peter A., Pharoah, Paul D.P. and Schmidt, Marjanka K.
    Published:
    2015
    Publication:
    Breast Cancer Research
    Volume:
    17, (1)
    Page Range:
    1-35
    doi:
    10.1186/s13058-015-0570-7
    PMID:
    25897948
  • Identification of novel genetic markers of breast cancer survival - Guo, Q., Schmidt, M.K., Kraft, P., Canisius, S., Chen, C., Khan, S., Tyrer, J., Bolla, M.K., Wang, Q., Dennis, J., Michailidou, K., Lush, M., Kar, S., Beesley, J., Dunning, A.M., Shah, M., Czene, K., Darabi, H., Eriksson, M., Lambrechts, D., Weltens, C., Leunen, K., Bojesen, S.E., Nordestgaard, B G., Nielsen, S.F., Flyger, H., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Blomqvist, C., Aittomaki, K., Fagerholm, R., Muranen, T.A., Couch, F.J., Olson, J.E., Vachon, C., Andrulis, I.L., Knight, J.A., Glendon, G., Mulligan, A.M., Broeks, A., Hogervorst, F.B., Haiman, C.A., Henderson, B.E., Schumacher, F., Le Marchand, L., Hopper, J.L., Tsimiklis, H., Apicella, C., Southey, M.C., Cox, A., Cross, S.S., Reed, M.W.R., Giles, G.G., Milne, R.L., McLean, C., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Hooning, M.J., Hollestelle, A., Martens, J.W.M., van den Ouweland, A.M.W., Marme, F., Schneeweiss, A., Yang, R., Burwinkel, B., Figueroa, J., Chanock, S.J., Lissowska, J., Sawyer, E.J., Tomlinson, I., Kerin, M.J., Miller, N., Brenner, H., Dieffenbach, A.K., Arndt, V., Holleczek, B., Mannermaa, A., Kataja, V., Kosma, V.-M., Hartikainen, J.M., Li, J., Brand, J.S., Humphreys, K., Devilee, P., Tollenaar, R.A.E.M., Seynaeve, C., Radice, P., Peterlongo, P., Bonanni, B., Mariani, P., Fasching, P. A., Beckmann, M.W., Hein, A., Ekici, A. B., Chenevix-Trench, G., Balleine, R., Phillips, K.-A., Benitez, J., Zamora, M.P., Arias Perez, J.I., Menendez, P., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Hamann, U., Kabisch, M., Ulmer, H. U., Rudiger, T., Margolin, S., Kristensen, V., Nord, S., Evans, D.G., Abraham, J.E., Earl, H.M., Hiller, L., Dunn, J.A., Bowden, S., Berg, C., Campa, D., Diver, W.R., Gapstur, S.M., Gaudet, M.M., Hankinson, S.E., Hoover, R.N., Husing, A., Kaaks, R., Machiela, M.J., Willett, W., Barrdahl, M., Canzian, F., Chin, S.-F., Caldas, C., Hunter, D.J., Lindstrom, S., Garcia-Closas, M., Hall, P., Easton, D.F., Eccles, D.M., Rahman, N., Nevanlinna, H. and Pharoah, P.D.P.
    Published:
    2015
    Publication:
    JNCI Journal of the National Cancer Institute
    Volume:
    107, (5)
    Page Range:
    1-9
    doi:
    10.1093/jnci/djv081
    PMID:
    25890600
  • The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients. - Fagerholm, Rainer, Schmidt, Marjanka K., Khan, Sofia, Rafiq, Sajjad, Tapper, William, Aittomäki, Kristiina, Greco, Dario, Heikkinen, Tuomas, Muranen, Taru A., Fasching, Peter A., Janni, Wolfgang, Weinshilboum, Richard, Loehberg, Christian R., Hopper, John L., Southey, Melissa C., Keeman, Renske, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Chenevix-Trench, Georgia, Lambrechts, Diether, Wildiers, Hans, Chang-Claude, Jenny, Seibold, Petra, Couch, Fergus J., Olson, Janet E., Andrulis, Irene L., Knight, Julia A., García-Closas, Montserrat, Figueroa, Jonine, Hooning, Maartje J., Jager, Agnes, Shah, Mitul, Perkins, Barbara J., Luben, Robert, Hamann, Ute, Kabisch, Maria, Czene, Kamila, Hall, Per, Easton, Douglas F., Pharoah, Paul D.P., Liu, Jianjun, Eccles, Diana, Blomqvist, Carl and Nevanlinna, Heli
    Published:
    2015
    Publication:
    Oncotarget
    Volume:
    6, (10)
    Page Range:
    7390-7407
    PMID:
    22685040
  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer - Rebbeck, Timothy R., Mitra, Nandita, Wan, Fei, Sinilnikova, Olga M., Healey, Sue, McGuffog, Lesley, Mazoyer, Sylvie, Chenevix-Trench, Georgia, Easton, Douglas F., Antoniou, Antonis C., Nathanson, Katherine L., Laitman, Yael, Kushnir, Anya, Paluch-Shimon, Shani, Berger, Raanan, Zidan, Jamal, Friedman, Eitan, Ehrencrona, Hans, Stenmark-Askmalm, Marie, Einbeigi, Zakaria, Loman, Niklas, Harbst, Katja, Rantala, Johanna, Melin, Beatrice, Huo, Dezheng, Olopade, Olufunmilayo I., Seldon, Joyce, Ganz, Patricia A., Nussbaum, Robert L., Chan, Salina B., Odunsi, Kunle, Gayther, Simon A., Domchek, Susan M., Arun, Banu K., Lu, Karen H., Mitchell, Gillian, Karlan, Beth Y., Walsh, Christine, Lester, Jenny, Godwin, Andrew K., Pathak, Harsh, Ross, Eric, Daly, Mary B., Whittemore, Alice S., John, Esther M., Miron, Alexander, Terry, Mary Beth, Chung, Wendy K., Goldgar, David E., Buys, Saundra S., Janavicius, Ramunas, Tihomirova, Laima, Tung, Nadine, Dorfling, Cecilia M., van Rensburg, Elizabeth J., Steele, Linda, Neuhausen, Susan L., Ding, Yuan Chun, Ejlertsen, Bent, Gerdes, Anne-Marie, Hansen, Thomas V.O., Ramón y Cajal, Teresa, Osorio, Ana, Benitez, Javier, Godino, Javier, Tejada, Maria-Isabel, Duran, Mercedes, Weitzel, Jeffrey N., Bobolis, Kristie A, Sand, Sharon R., Fontaine, Annette, Savarese, Antonella, Pasini, Barbara, Peissel, Bernard, Bonanni, Bernardo, Zaffaroni, Daniela, Vignolo-Lutati, Francesca, Scuvera, Giulietta, Giannini, Giuseppe, Bernard, Loris, Genuardi, Maurizio, Radice, Paolo, Dolcetti, Riccardo, Manoukian, Siranoush, Pensotti, Valeria, Gismondi, Viviana, Yannoukakos, Drakoulis, Fostira, Florentia, Garber, Judy, Torres, Diana, Rashid, Muhammad Usman, Hamann, Ute, Peock, Susan, Frost, Debra, Platte, Radka, Evans, D. Gareth, Eeles, Rosalind, Davidson, Rosemarie, Eccles, Diana, Cole, Trevor, Cook, Jackie, Brewer, Carole, Hodgson, Shirley, Morrison, Patrick J., Walker, Lisa, Porteous, Mary E., Kennedy, M. John, Izatt, Louise, Adlard, Julian, Donaldson, Alan, Ellis, Steve, Sharma, Priyanka, Schmutzler, Rita Katharina, Wappenschmidt, Barbara, Becker, Alexandra, Rhiem, Kerstin, Hahnen, Eric, Engel, Christoph, Meindl, Alfons, Engert, Stefanie, Ditsch, Nina, Arnold, Norbert, Plendl, Hans Jörg, Mundhenke, Christoph, Niederacher, Dieter, Fleisch, Markus, Sutter, Christian, Bartram, C.R., Dikow, Nicola, Wang-Gohrke, Shan, Gadzicki, Dorothea, Steinemann, Doris, Kast, Karin, Beer, Marit, Varon-Mateeva, Raymonda, Gehrig, Andrea, Weber, Bernhard H., Stoppa-Lyonnet, Dominique, Sinilnikova, Olga M., Mazoyer, Sylvie, Houdayer, Claude, Belotti, Muriel, Gauthier-Villars, Marion, Damiola, Francesca, Boutry-Kryza, Nadia, Lasset, Christine, Sobol, Hagay, Peyrat, Jean-Philippe, Muller, Danièle, Fricker, Jean-Pierre, Collonge-Rame, Marie-Agnès, Mortemousque, Isabelle, Nogues, Catherine, Rouleau, Etienne, Isaacs, Claudine, De Paepe, Anne, Poppe, Bruce, Claes, Kathleen, De Leeneer, Kim, Piedmonte, Marion, Rodriguez, Gustavo, Wakely, Katie, Boggess, John, Blank, Stephanie V., Basil, Jack, Azodi, Masoud, Phillips, Kelly-Anne, Caldes, Trinidad, de la Hoya, Miguel, Romero, Atocha, Nevanlinna, Heli, Aittomäki, Kristiina, van der Hout, Annemarie H., Hogervorst, Frans B. L., Verhoef, Senno, Collée, J. Margriet, Seynaeve, Caroline, Oosterwijk, Jan C., Gille, Johannes J P., Wijnen, Juul T., Garcia, Encarna B. Gómez, Kets, Carolien M., Ausems, Margreet G E.M., Aalfs, Cora M., Devilee, Peter, Mensenkamp, Arjen R., Kwong, Ava, Olah, Edith, Papp, Janos, Diez, Orland, Lazaro, Conxi, Darder, Esther, Blanco, Ignacio, Salinas, Mónica, Jakubowska, Anna, Lubinski, Jan, Gronwald, Jacek, Jaworska-Bieniek, Katarzyna, Durda, Katarzyna, Sukiennicki, Grzegorz, Huzarski, Tomasz, Byrski, Tomasz, Cybulski, Cezary, Toloczko-Grabarek, Aleksandra, Zlowocka-Perlowska, Elzbieta, Menkiszak, Janusz, Arason, Adalgeir, Barkardottir, Rosa B., Simard, Jacques, Laframboise, Rachel, Montagna, Marco, Agata, Simona, Alducci, Elisa, Peixoto, Ana, Teixeira, Manuel R., Spurdle, Amanda B., Lee, Min Hyuk, Park, Sue K., Kim, Sung-Won, Friebel, Tara M., Couch, Fergus J., Lindor, Noralane M., Pankratz, Vernon S., Guidugli, Lucia, Wang, Xianshu, Tischkowitz, Marc, Foretova, Lenka, Vijai, Joseph, Offit, Kenneth, Robson, Mark, Rau-Murthy, Rohini, Kauff, Noah, Fink-Retter, Anneliese, Singer, Christian F., Rappaport, Christine, Gschwantler-Kaulich, Daphne, Pfeiler, Georg, Tea, Muy-Kheng, Berger, Andreas, Greene, Mark H., Mai, Phuong L., Imyanitov, Evgeny N., Toland, Amanda Ewart, Senter, Leigha, Bojesen, Anders, Pedersen, Inge Sokilde, Skytte, Anne-Bine, Sunde, Lone, Thomassen, Mads, Moeller, Sanne Traasdahl, Kruse, Torben A., Jensen, Uffe Birk, Caligo, Maria Adelaide, Aretini, Paolo, Teo, Soo-Hwang, Selkirk, Christina G., Hulick, Peter J. and Andrulis, Irene
    Published:
    2015
    Publication:
    JAMA The Journal of the American Medical Association
    Volume:
    313, (13)
    Page Range:
    1347-1361
    doi:
    10.1001/jama.2014.5985
    PMID:
    25849179
  • An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ?40 years at breast cancer diagnosis - Maishman, T, Copson, Ellen, Stanton, L., Gerty, Sue, Dicks, E., Durcan, Lorraine, Wishart, G.C., Pharoah, P. and Eccles, Diana
    Published:
    2015
    Publication:
    British Journal of Cancer
    Volume:
    112, (6)
    Page Range:
    983-991
    doi:
    10.1038/bjc.2015.57
    PMID:
    11181660
  • Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study - Lee, Alice W., Tyrer, Jonathan P., Doherty, Jennifer A., Stram, Douglas A., Kupryjanczyk, Jolanta, Dansonka-Mieszkowska, Agnieszka, Plisiecka-Halasa, Joanna, Spiewankiewicz, Beata, Myers, Emily J., Chenevix-Trench, Georgia, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander, Vergote, Ignace, Van Nieuwenhuysen, Els, Lambrechts, Diether, Wicklund, Kristine G., Eilber, Ursula, Wang-Gohrke, Shan, Chang-Claude, Jenny, Rudolph, Anja, Sucheston-Campbell, Lara, Odunsi, Kunle, Moysich, Kirsten B., Shvetsov, Yurii B., Thompson, Pamela J., Goodman, Marc T., Wilkens, Lynne R., Dörk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo B., Bogdanova, Natalia, Pelttari, Liisa M., Nevanlinna, Heli, Leminen, Arto, Edwards, Robert P., Kelley, Joseph L., Harter, Philipp, Schwaab, Ira, Heitz, Florian, du Bois, Andreas, Orsulic, Sandra, Lester, Jenny, Walsh, Christine, Karlan, Beth Y., Hogdall, Estrid, Kjaer, Susanne K., Jensen, Allan, Vierkant, Robert A., Cunningham, Julie M., Goode, Ellen L., Fridley, Brooke L., Southey, Melissa C., Giles, Graham G., Bruinsma, Fiona, Wu, Xifeng, Hildebrandt, Michelle A.T., Lu, Karen, Liang, Dong, Bisogna, Maria, Levine, Douglas A., Weber, Rachel Palmieri, Schildkraut, Joellen M., Iversen, Edwin S., Berchuck, Andrew, Terry, Kathryn L., Cramer, Daniel W., Tworoger, Shelley S., Poole, Elizabeth M., Olson, Sara H., Orlow, Irene, Bandera, Elisa V., Bjorge, Line, Tangen, Ingvild L., Salvesen, Helga B., Krakstad, Camilla, Massuger, Leon F.A.G., Kiemeney, Lambertus A., Aben, Katja K.H., van Altena, Anne M., Bean, Yukie, Pejovic, Tanja, Kellar, Melissa, Le, Nhu D., Cook, Linda S., Kelemen, Linda E., Brooks-Wilson, Angela, Lubinski, Jan, Gronwald, Jacek, Cybulski, Cezary, Jakubowska, Anna, Wentzensen, Nicolas, Brinton, Louise A., Lissowska, Jolanta, Yang, Hannah, Nedergaard, Lotte, Lundvall, Lene, Hogdall, Claus, Song, Honglin, Campbell, Ian G., Eccles, Diana, Glasspool, Rosalind, Siddiqui, Nadeem, Carty, Karen, Paul, James, McNeish, Iain A., Sieh, Weiva, McGuire, Valerie, Rothstein, Joseph H., Whittemore, Alice S., McLaughlin, John R., Risch, Harvey A., Phelan, Catherine M., Anton-Culver, Hoda, Ziogas, Argyrios, Menon, Usha, Ramus, Susan J., Gentry-Maharaj, Aleksandra, Harrington, Patricia, Pike, Malcolm C., Modugno, Francesmary, Rossing, Mary Anne, Ness, Roberta B., Pharoah, Paul D.P., Stram, Daniel O., Wu, Anna H. and Pearce, Celeste Leigh
    Published:
    2015
    Publication:
    Gynecologic Oncology
    Volume:
    136, (3)
    Page Range:
    542-548
    doi:
    10.1016/j.ygyno.2014.12.017
  • Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer - Couch, F.J., Hart, S.N., Sharma, P., Toland, A.E., Wang, X., Miron, P., Olson, J.E., Godwin, A.K., Pankratz, V.S., Olswold, C., Slettedahl, S., Hallberg, E., Guidugli, L., Davila, J.I., Beckmann, M.W., Janni, W., Rack, B., Ekici, A.B., Slamon, D.J., Konstantopoulou, I., Fostira, F., Vratimos, A., Fountzilas, G., Pelttari, L.M., Tapper, W.J., Durcan, L., Cross, S.S., Pilarski, R., Shapiro, C. L., Klemp, J., Yao, S., Garber, J., Cox, A., Brauch, H., Ambrosone, C., Nevanlinna, H., Yannoukakos, D., Slager, S.L., Vachon, C.M., Eccles, D.M. and Fasching, P.A.
    Published:
    2015
    Publication:
    Journal of Clinical Oncology
    Volume:
    33, (4)
    Page Range:
    304-311
    doi:
    10.1200/JCO.2014.57.1414
    PMID:
    25452441
  • Identification of six new susceptibility loci for invasive epithelial ovarian cancer - Kuchenbaecker, Karoline B., Ramus, Susan J., Tyrer, Jonathan, Lee, Andrew, Shen, Howard C., Beesley, Jonathan, Lawrenson, Kate, McGuffog, Lesley, Healey, Sue, Lee, Janet M., Spindler, Tassja J., Lin, Yvonne G., Pejovic, Tanja, Bean, Yukie, Li, Qiyuan, Coetzee, Simon, Hazelett, Dennis, Miron, Alexander, Southey, Melissa, Terry, Mary Beth, Goldgar, David E., Buys, Saundra S., Janavicius, Ramunas, Dorfling, Cecilia M., van Rensburg, Elizabeth J., Neuhausen, Susan L., Ding, Yuan Chun, Hansen, Thomas V.O., Jønson, Lars, Gerdes, Anne-Marie, Ejlertsen, Bent, Barrowdale, Daniel, Dennis, Joe, Benitez, Javier, Osorio, Ana, Garcia, Maria Jose, Komenaka, Ian, Weitzel, Jeffrey N., Ganschow, Pamela, Peterlongo, Paolo, Bernard, Loris, Viel, Alessandra, Bonanni, Bernardo, Peissel, Bernard, Manoukian, Siranoush, Radice, Paolo, Papi, Laura, Ottini, Laura, Fostira, Florentia, Konstantopoulou, Irene, Garber, Judy, Frost, Debra, Perkins, Jo, Platte, Radka, Ellis, Steve, , , Godwin, Andrew K, Schmutzler, Rita Katharina, Meindl, Alfons, Engel, Christoph, Sutter, Christian, Sinilnikova, Olga M, Damiola, Francesca, Mazoyer, Sylvie, Stoppa-Lyonnet, Dominique, Claes, Kathleen, De Leeneer, Kim, Kirk, Judy, Rodriguez, Gustavo C., Piedmonte, Marion, O'Malley, David M., de la Hoya, Miguel, Caldes, Trinidad, Aittomäki, Kristiina, Nevanlinna, Heli, Collée, J. Margriet, Rookus, Matti A., Oosterwijk, Jan C., Tihomirova, Laima, Tung, Nadine, Hamann, Ute, Isaccs, Claudine, Tischkowitz, Marc, Imyanitov, Evgeny N., Caligo, Maria A., Campbell, Ian G., Hogervorst, Frans B.L., Olah, Edith, Diez, Orland, Blanco, Ignacio, Brunet, Joan, Lazaro, Conxi, Pujana, Miquel Angel, Jakubowska, Anna, Gronwald, Jacek, Lubinski, Jan, Sukiennicki, Grzegorz, Barkardottir, Rosa B, Plante, Marie, Simard, Jacques, Soucy, Penny, Montagna, Marco, Tognazzo, Silvia, Teixeira, Manuel R., Pankratz, Vernon S., Wang, Xianshu, Lindor, Noralane, Szabo, Csilla I., Kauff, Noah, Vijai, Joseph, Aghajanian, Carol A., Pfeiler, Georg, Berger, Andreas, Singer, Christian F., Tea, Muy-Kheng, Phelan, Catherine M., Greene, Mark H., Mai, Phuong L., Rennert, Gad, Mulligan, Anna Marie, Tchatchou, Sandrine, Andrulis, Irene L., Glendon, Gord, Toland, Amanda Ewart, Jensen, Uffe Birk, Kruse, Torben A., Thomassen, Mads, Bojesen, Anders, Zidan, Jamal, Friedman, Eitan, Laitman, Yael, Soller, Maria, Liljegren, Annelie, Arver, Brita, Einbeigi, Zakaria, Stenmark-Askmalm, Marie, Olopade, Olufunmilayo I., Nussbaum, Robert L., Rebbeck, Timothy R, Nathanson, Katherine L., Domchek, Susan M., Lu, Karen H., Karlan, Beth Y., Walsh, Christine, Lester, Jenny, Hein, Alexander, Ekici, Arif B., Beckmann, Matthias W., Fasching, Peter A., Lambrechts, Diether, Van Nieuwenhuysen, Els, Vergote, Ignace, Lambrechts, Sandrina, Dicks, Ed, Doherty, Jennifer A., Wicklund, Kristine G., Rossing, Mary Anne, Rudolph, Anja, Chang-Claude, Jenny, Wang-Gohrke, Shan, Eilber, Ursula, Moysich, Kirsten B., Odunsi, Kunle, Sucheston, Lara, Lele, Shashi, Wilkens, Lynne R., Goodman, Marc T., Thompson, Pamela J., Shvetsov, Yurii B., Runnebaum, Ingo B., Dürst, Matthias, Hillemanns, Peter, Dörk, Thilo, Antonenkova, Natalia, Bogdanova, Natalia, Leminen, Arto, Pelttari, Liisa M., Butzow, Ralf, Modugno, Francesmary, Kelley, Joseph L., Edwards, Robert P., Ness, Roberta B., du Bois, Andreas, Heitz, Florian, Schwaab, Ira, Harter, Philipp, Matsuo, Keitaro, Hosono, Satoyo, Orsulic, Sandra, Jensen, Allan, Kjaer, Susanne Kruger, Hogdall, Estrid, Hasmad, Hanis Nazihah, Azmi, Mat Adenan Noor, Teo, Soo-Hwang, Woo, Yin-Ling, Fridley, Brooke L., Goode, Ellen L., Cunningham, Julie M., Vierkant, Robert A., Bruinsma, Fiona, Giles, Graham G., Liang, Dong, Hildebrandt, Michelle A.T., Wu, Xifeng, Levine, Douglas A., Bisogna, Maria, Berchuck, Andrew, Iversen, Edwin S., Schildkraut, Joellen M., Concannon, Patrick, Weber, Rachel Palmieri, Cramer, Daniel W., Terry, Kathryn L., Poole, Elizabeth M., Tworoger, Shelley S., Bandera, Elisa V., Orlow, Irene, Olson, Sara H., Krakstad, Camilla, Salvesen, Helga B., Tangen, Ingvild L., Bjorge, Line, van Altena, Anne M., Aben, Katja K.H., Kiemeney, Lambertus A., Massuger, Leon F.A.G., Kellar, Melissa, Brooks-Wilson, Angela, Kelemen, Linda E., Cook, Linda S., Le, Nhu D., Cybulski, Cezary, Yang, Hannah, Lissowska, Jolanta, Brinton, Louise A., Wentzensen, Nicolas, Hogdall, Claus, Lundvall, Lene, Nedergaard, Lotte, Baker, Helen, Song, Honglin, Eccles, Diana, McNeish, Ian, Paul, James, Carty, Karen, Siddiqui, Nadeem, Glasspool, Rosalind, Whittemore, Alice S., Rothstein, Joseph H., McGuire, Valerie, Sieh, Weiva, Ji, Bu-Tian, Zheng, Wei, Shu, Xiao-Ou, Gao, Yu-Tang, Rosen, Barry, Risch, Harvey A., McLaughlin, John R., Narod, Steven A., Monteiro, Alvaro N., Chen, Ann, Lin, Hui-Yi, Permuth-Wey, Jenny, Sellers, Thomas A., Tsai, Ya-Yu, Chen, Zhihua, Ziogas, Argyrios, Anton-Culver, Hoda, Gentry-Maharaj, Aleksandra, Menon, Usha, Harrington, Patricia, Lee, Alice W., Wu, Anna H., Pearce, Celeste L., Coetzee, Gerry, Pike, Malcolm C., Dansonka-Mieszkowska, Agnieszka, Timorek, Agnieszka, Rzepecka, Iwona K., Kupryjanczyk, Jolanta, Freedman, Matt, Noushmehr, Houtan, Easton, Douglas F., Offit, Kenneth, Couch, Fergus J., Gayther, Simon, Pharoah, Paul P., Antoniou, Antonis C. and Chenevix-Trench, Georgia
    Published:
    2015
    Publication:
    Nature Genetics
    Volume:
    47, (2)
    Page Range:
    164-171
    doi:
    10.1038/ng.3185
    PMID:
    25581431
  • Quantifying the cumulative effect of low-penetrance genetic variants on breast cancer risk - Smyth, Conor, Spakulova, Iva, Cotton-Barratt, Owen, Rafiq, Sajjad, Tapper, William, Upstill-Goddard, Rosanna, Hopper, John, Makalic, Enes, Schmidt, Daniel, Kapuscinski, Miroslav, Fliege, Jörg, Collins, Andrew, Brodzki, Jacek, Eccles, Diana and MacArthur, Ben D.
    Published:
    2015
    Publication:
    Molecular Genetics & Genomic Medicine
    Volume:
    3, (3)
    Page Range:
    182-188
    doi:
    10.1002/mgg3.129
  • Obesity and the outcome of young breast cancer patients in the UK: the POSH study - Copson, E.R., Cutress, R.I., Maishman, T., Eccles, B.K., Gerty, S., Stanton, L., Altman, D.G., Durcan, L., Wong, C., Simmonds, P.D., Jones, L. and Eccles, D.M.
    Published:
    2015
    Publication:
    Annals of Oncology
    Volume:
    26, (1)
    Page Range:
    101-112
    doi:
    10.1093/annonc/mdu509
    PMID:
    25361993
  • Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers - Peterlongo, P., Chang-Claude, J., Moysich, K.B., Rudolph, A., Schmutzler, R.K., Simard, J., Soucy, P., Eeles, R.A., Easton, D.F., Hamann, U., Wilkening, S., Chen, B., Rookus, M. A., Schmidt, M.K., van der Baan, F.H., Spurdle, A.B., Walker, L.C., Lose, F., Maia, A.-T., Montagna, M., Matricardi, L., Lubinski, J., Jakubowska, A., Gomez Garcia, E.B., Olopade, O.I., Nussbaum, R.L., Nathanson, K.L., Domchek, S.M., Rebbeck, T.R., Arun, B.K., Karlan, B.Y., Orsulic, S., Lester, J., Chung, W.K., Miron, A., Southey, M.C., Goldgar, D.E., Buys, S.S., Janavicius, R., Dorfling, C.M., van Rensburg, E.J., Ding, Y.C., Neuhausen, S.L., Hansen, T.V.O., Gerdes, A.-M., Ejlertsen, B., Jonson, L., Osorio, A., Martinez-Bouzas, C., Benitez, J., Conway, E. E., Blazer, K.R., Weitzel, J.N., Manoukian, S., Peissel, B., Zaffaroni, D., Scuvera, G., Barile, M., Ficarazzi, F., Mariette, F., Fortuzzi, S., Viel, A., Giannini, G., Papi, L., Martayan, A., Tibiletti, M.G., Radice, P., Vratimos, A., Fostira, F., Garber, J.E., Donaldson, A., Brewer, C., Foo, C., Evans, D.G.R., Frost, D., Eccles, D., Brady, A., Cook, J., Tischkowitz, M., Adlard, J., Barwell, J., Walker, L., Izatt, L., Side, L.E., Kennedy, M.J., Rogers, M.T., Porteous, M.E., Morrison, P.J., Platte, R., Davidson, R., Hodgson, S. V., Ellis, S., Cole, T., Godwin, A. K., Claes, K., Van Maerken, T., Meindl, A., Gehrig, A., Sutter, C., Engel, C., Niederacher, D., Steinemann, D., Plendl, H., Kast, K., Rhiem, K., Ditsch, N., Arnold, N., Varon-Mateeva, R., Wappenschmidt, B., Wang-Gohrke, S., Bressac-de Paillerets, B., Buecher, B., Delnatte, C., Houdayer, C., Stoppa-Lyonnet, D., Damiola, F., Coupier, I., Barjhoux, L., Venat-Bouvet, L., Golmard, L., Boutry-Kryza, N., Sinilnikova, O. M., Caron, O., Pujol, P., Mazoyer, S., Belotti, M., Piedmonte, M., Friedlander, M.L., Rodriguez, G.C., Copeland, L.J., de la Hoya, M., Segura, P. P., Nevanlinna, H., Aittomaki, K., van Os, T. A. M., Meijers-Heijboer, H. E. J., van der Hout, A. H., Vreeswijk, M. P. G., Hoogerbrugge, N., Ausems, M. G. E. M., van Doorn, H. C., Collee, J. M., Olah, E., Diez, O., Blanco, I., Lazaro, C., Brunet, J., Feliubadalo, L., Cybulski, C., Gronwald, J., Durda, K., Jaworska-Bieniek, K., Sukiennicki, G., Arason, A., Chiquette, J., Teixeira, M. R., Olswold, C., Couch, F. J., Lindor, N. M., Wang, X., Szabo, C. I., Offit, K., Corines, M., Jacobs, L., Robson, M. E., Zhang, L., Joseph, V., Berger, A., Singer, C. F., Rappaport, C., Kaulich, D. G., Pfeiler, G., Tea, M.-K. M., Phelan, C. M., Greene, M. H., Mai, P. L., Rennert, G., Mulligan, A. M., Glendon, G., Tchatchou, S., Andrulis, I. L., Toland, A. E., Bojesen, A., Pedersen, I. S., Thomassen, M., Jensen, U. B., Laitman, Y., Rantala, J., von Wachenfeldt, A., Ehrencrona, H., Askmalm, M. S., Borg, A., Kuchenbaecker, K. B., McGuffog, L., Barrowdale, D., Healey, S., Lee, A., Pharoah, P. D. P., Chenevix-Trench, G., Antoniou, A. C. and Friedman, E.
    Published:
    2015
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    24, (1)
    Page Range:
    308-316
    doi:
    10.1158/1055-9965.EPI-14-0532
    PMID:
    25336561
  • Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer - Saladores, P., Mürdter, T., Eccles, Diana, Chowbay, B., Zgheib, N.K., Winter, S., Ganchev, B., Eccles, Bryony, Gerty, Sue, Tfayli, A., Lim, J.S.L., Yap, Y.S., Ng, R.C.H., Wong, N.S., Dent, R., Habbal, M.Z., Schaeffeler, E., Eichelbaum, M., Schroth, W., Schwab, M. and Brauch, H.
    Published:
    2015
    Publication:
    The Pharmacogenomics Journal
    Volume:
    15, (1)
    Page Range:
    84-94
    doi:
    10.1038/tpj.2014.34
    PMID:
    25091503
  • BRCA1 Circos: a visualisation resource for functional analysis of missense variants - Jhuraney, A., Velkova, A., Johnson, R.C., Kessing, B., Carvalho, R.S., Whiley, P., Spurdle, A.B., Vreeswijk, M.P.G., Caputo, S.M., Millot, G.A., Vega, A., Coquelle, N., Galli, A., Eccles, D., Blok, M.J., Pal, T., van der Luijt, R.B., Santamarina Pena, M., Neuhausen, S.L., Donenberg, T., Machackova, E., Thomas, S., Vallee, M., Couch, F.J., Tavtigian, S.V., Glover, J.N.M., Carvalho, M.A., Brody, L.C., Sharan, S.K. and Monteiro, A.N.
    Published:
    2015
    Publication:
    Journal of Medical Genetics
    Volume:
    52, (4)
    Page Range:
    224-230
    doi:
    10.1136/jmedgenet-2014-102766
    PMID:
    25643705
  • Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers - Kuchenbaecker, Karoline B, Neuhausen, Susan L, Robson, Mark, Barrowdale, Daniel, McGuffog, Lesley, Mulligan, Anna Marie, Andrulis, Irene L, Spurdle, Amanda B, Schmidt, Marjanka K, Schmutzler, Rita K, Engel, Christoph, Wappenschmidt, Barbara, Nevanlinna, Heli, Thomassen, Mads, Southey, Melissa, Radice, Paolo, Ramus, Susan J, Domchek, Susan M, Nathanson, Katherine L, Lee, Andrew, Healey, Sue, Nussbaum, Robert L, Rebbeck, Timothy R, Arun, Banu K, James, Paul, Karlan, Beth Y, Lester, Jenny, Cass, Ilana, Terry, Mary Beth, Daly, Mary B, Goldgar, David E, Buys, Saundra S, Janavicius, Ramunas, Tihomirova, Laima, Tung, Nadine, Dorfling, Cecilia M, van Rensburg, Elizabeth J, Steele, Linda, v O Hansen, Thomas, Ejlertsen, Bent, Gerdes, Anne-Marie, Nielsen, Finn C, Dennis, Joe, Cunningham, Julie, Hart, Steven, Slager, Susan, Osorio, Ana, Benitez, Javier, Duran, Mercedes, Weitzel, Jeffrey N, Tafur, Isaac, Hander, Mary, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Roversi, Gaia, Scuvera, Giulietta, Bonanni, Bernardo, Mariani, Paolo, Volorio, Sara, Dolcetti, Riccardo, Varesco, Liliana, Papi, Laura, Tibiletti, Maria Grazia, Giannini, Giuseppe, Fostira, Florentia, Konstantopoulou, Irene, Garber, Judy, Hamann, Ute, Donaldson, Alan, Brewer, Carole, Foo, Claire, Evans, D Gareth, Frost, Debra, Eccles, Diana, Douglas, Fiona, Brady, Angela, Cook, Jackie, Tischkowitz, Marc, Adlard, Julian, Barwell, Julian, Ong, Kai-ren, Walker, Lisa, Izatt, Louise, Side, Lucy E, Kennedy, M John, Rogers, Mark T, Porteous, Mary E, Morrison, Patrick J, Platte, Radka, Eeles, Ros, Davidson, Rosemarie, Hodgson, Shirley, Ellis, Steve, Godwin, Andrew K, Rhiem, Kerstin, Meindl, Alfons, Ditsch, Nina, Arnold, Norbert, Plendl, Hansjoerg, Niederacher, Dieter, Sutter, Christian, Steinemann, Doris, Bogdanova-Markov, Nadja, Kast, Karin, Varon-Mateeva, Raymonda, Wang-Gohrke, Shan, Gehrig, Andrea, Markiefka, Birgid, Buecher, Bruno, Lefol, Cédrick, Stoppa-Lyonnet, Dominique, Rouleau, Etienne, Prieur, Fabienne, Damiola, Francesca, Barjhoux, Laure, Faivre, Laurence, Longy, Michel, Sevenet, Nicolas, Sinilnikova, Olga M, Mazoyer, Sylvie, Bonadona, Valérie, Caux-Moncoutier, Virginie, Isaacs, Claudine, Van Maerken, Tom, Claes, Kathleen, Piedmonte, Marion, Andrews, Lesley, Hays, John, Rodriguez, Gustavo C, Caldes, Trinidad, de la Hoya, Miguel, Khan, Sofia, Hogervorst, Frans B L, Aalfs, Cora M, de Lange, J L, Meijers-Heijboer, Hanne E J, van der Hout, Annemarie H, Wijnen, Juul T, van Roozendaal, K E P, Mensenkamp, Arjen R, van den Ouweland, Ans M W, van Deurzen, Carolien H M, van der Luijt, Rob B, Olah, Edith, Diez, Orland, Lazaro, Conxi, Blanco, Ignacio, Teulé, Alex, Menendez, Mireia, Jakubowska, Anna, Lubinski, Jan, Cybulski, Cezary, Gronwald, Jacek, Jaworska-Bieniek, Katarzyna, Durda, Katarzyna, Arason, Adalgeir, Maugard, Christine, Soucy, Penny, Montagna, Marco, Agata, Simona, Teixeira, Manuel R, Olswold, Curtis, Lindor, Noralane, Pankratz, Vernon S, Hallberg, Emily, Wang, Xianshu, Szabo, Csilla I, Vijai, Joseph, Jacobs, Lauren, Corines, Marina, Lincoln, Anne, Berger, Andreas, Fink-Retter, Anneliese, Singer, Christian F, Rappaport, Christine, Kaulich, Daphne Gschwantler, Pfeiler, Georg, Tea, Muy-Kheng, Phelan, Catherine M, Mai, Phuong L, Greene, Mark H, Rennert, Gad, Imyanitov, Evgeny N, Glendon, Gord, Toland, Amanda Ewart, Bojesen, Anders, Pedersen, Inge Sokilde, Jensen, Uffe Birk, Caligo, Maria A, Friedman, Eitan, Berger, Raanan, Laitman, Yael, Rantala, Johanna, Arver, Brita, Loman, Niklas, Borg, Ake, Ehrencrona, Hans, Olopade, Olufunmilayo I, Simard, Jacques, Easton, Douglas F, Chenevix-Trench, Georgia, Offit, Kenneth, Couch, Fergus J and Antoniou, Antonis C
    Published:
    2014
    Publication:
    Breast Cancer Research
    Volume:
    16, (6)
    Page Range:
    3416
    doi:
    10.1186/s13058-014-0492-9
    PMID:
    25919761
  • A genome wide meta-analysis study for identification of common variation associated with breast cancer prognosis - Miao, Xiaoping, Rafiq, Sajjad, Khan, Sofia, Tapper, William, Collins, Andrew, Upstill-Goddard, Rosanna, Gerty, Susan, Blomqvist, Carl, Aittomäki, Kristiina, Couch, Fergus J., Liu, Jianjun, Nevanlinna, Heli and Eccles, Diana
    Published:
    2014
    Publication:
    PLoS ONE
    Volume:
    9, (12)
    Page Range:
    e101488-[10pp]
    doi:
    10.1371/journal.pone.0101488
    PMID:
    25526632
  • The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services - Evans, D. Gareth R., Barwell, Julian, Eccles, Diana M, Collins, Amanda, Izatt, Louise, Jacobs, Chris, Donaldson, Alan, Brady, Angela F, Cuthbert, Andrew, Harrison, Rachel, Thomas, Sue, Howell, Anthony, Miedzybrodzka, Zosia and Murray, Alex
    Published:
    2014
    Publication:
    Breast Cancer Research
    Volume:
    16, (5)
    Page Range:
    442-[6pp]
    doi:
    10.1186/s13058-014-0442-6
    PMID:
    25510853
  • Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study - Bancroft, Elizabeth K., Page, Elizabeth C., Castro, Elena, Lilja, Hans, Vickers, Andrew, Sjoberg, Daniel, Assel, Melissa, Foster, Christopher S., Mitchell, Gillian, Drew, Kate, Mæhle, Lovise, Axcrona, Karol, Evans, D. Gareth, Bulman, Barbara, Eccles, Diana, McBride, Donna, van Asperen, Christi, Vasen, Hans, Kiemeney, Lambertus A., Ringelberg, Janneke, Cybulski, Cezary, Wokolorczyk, Dominika, Selkirk, Christina, Hulick, Peter J., Bojesen, Anders, Skytte, Anne-Bine, Lam, Jimmy, Taylor, Louise, Oldenburg, Rogier, Cremers, Ruben, Verhaegh, Gerald, van Zelst-Stams, Wendy A., Oosterwijk, Jan C., Blanco, Ignacio, Salinas, Monica, Cook, Jackie, Rosario, Derek J., Buys, Saundra, Conner, Tom, Ausems, Margreet G., Ong, Kai-ren, Hoffman, Jonathan, Domchek, Susan, Powers, Jacquelyn, Teixeira, Manuel R., Maia, Sofia, Foulkes, William D., Taherian, Nassim, Ruijs, Marielle, den Enden, Apollonia T. Helderman-van, Izatt, Louise, Davidson, Rosemarie, Adank, Muriel A., Walker, Lisa, Schmutzler, Rita, Tucker, Kathy, Kirk, Judy, Hodgson, Shirley, Harris, Marion, Douglas, Fiona, Lindeman, Geoffrey J., Zgajnar, Janez, Tischkowitz, Marc, Clowes, Virginia E., Susman, Rachel, Ramón y Cajal, Teresa, Patcher, Nicholas, Gadea, Neus, Spigelman, Allan, van Os, Theo, Liljegren, Annelie, Side, Lucy, Brewer, Carole, Brady, Angela F., Donaldson, Alan, Stefansdottir, Vigdis, Friedman, Eitan, Chen-Shtoyerman, Rakefet, Amor, David J., Copakova, Lucia, Barwell, Julian, Giri, Veda N., Murthy, Vedang, Nicolai, Nicola, Teo, Soo-Hwang, Greenhalgh, Lynn, Strom, Sara, Henderson, Alex, McGrath, John, Gallagher, David, Aaronson, Neil, Ardern-Jones, Audrey, Bangma, Chris, Dearnaley, David, Costello, Philandra, Eyfjord, Jorunn, Rothwell, Jeanette, Falconer, Alison, Gronberg, Henrik, Hamdy, Freddie C., Johannsson, Oskar, Khoo, Vincent, Kote-Jarai, Zsofia, Lubinski, Jan, Axcrona, Ulrika, Melia, Jane, McKinley, Joanne, Mitra, Anita V., Moynihan, Clare, Rennert, Gad, Suri, Mohnish, Wilson, Penny, Killick, Emma, Moss, Sue and Eeles, Rosalind A.
    Published:
    2014
    Publication:
    European Urology
    Volume:
    66, (3)
    Page Range:
    489-499
    doi:
    10.1016/j.eururo.2014.01.003
    PMID:
    24484606
  • Variation in NF- kB signaling pathways and survival in invasive epithelial ovarian cancer - Block, M.S., Charbonneau, B., Vierkant, R., Fogarty, Z., Bamlet, W.R., Pharoah, P.D.P., Rossing, M.A., Cramer, D., Pearce, C.L., Schildkraut, J., Menon, U., Kjaer, S.K., Levine, D.A., Gronwald, J., Culver, H.A., Whittemore, A.S., Karlan, B.Y., Lambrechts, D., Wentzensen, N., Kupryjanczyk, J., Chang-Claude, J., Bandera, E.V., Hogdall, E., Heitz, F., Kaye, S.B., Fasching, P.A., Campbell, I., Goodman, M.T., Pejovic, T., Bean, Y.T., Hays, L.E., Lurie, G., Eccles, D., Hein, A., Beckmann, M.W., Ekici, A.B., Paul, J., Brown, R., Flanagan, J.M., Harter, P., du Bois, A., Schwaab, I., Hogdall, C.K., Lundvall, L., Olson, S.H., Orlow, I., Paddock, L.E., Rudolph, A., Eilber, U., Dansonka-Mieszkowska, A., Rzepecka, I.K., Ziolkowska-Seta, I., Brinton, L.A., Yang, H., Garcia-Closas, M., Despierre, E., Lambrechts, S., Vergote, I., Walsh, C.S., Lester, J., Sieh, W., McGuire, V., Rothstein, J.H., Ziogas, A., Lubi ski, J., Cybulski, C., Menkiszak, J., Jensen, A., Gayther, S.A., Ramus, S.J., Gentry-Maharaj, A., Berchuck, A., Wu, A.H., Pike, M.C., Van Den Berg, D., Terry, K.L., Vitonis, A.F., Ramirez, S.M., Rider, D.N., Knutson, K.L., Sellers, T.A., Phelan, C.M., Doherty, J.A., Johnatty, S.E., deFazio, A., Song, H., Tyrer, J., Kalli, K.R., Fridley, B.L., Cunningham, J.M. and Goode, E.L.
    Published:
    2014
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    23, (7)
    Page Range:
    1421-1427
    doi:
    10.1158/1055-9965.EPI-13-0962
    PMID:
    24740199
  • Therapeutic targeting of Integrin v 6 in breast cancer - Moore, K.M., Thomas, G J., Duffy, S.W., Warwick, J., Gabe, R., Chou, P., Ellis, I.O., Green, A.R., Haider, S., Brouilette, K., Saha, A., Vallath, S., Bowen, R., Chelala, C., Eccles, D., Tapper, W.J., Thompson, A.M., Quinlan, P., Jordan, L., Gillett, C., Brentnall, A., Violette, S., Weinreb, P.H., Kendrew, J., Barry, S.T., Hart, I.R., Jones, J.L. and Marshall, J.F.
    Published:
    2014
    Publication:
    JNCI Journal of the National Cancer Institute
    Volume:
    106, (8)
    Page Range:
    dju169-dju169
    doi:
    10.1093/jnci/dju169
    PMID:
    24974129
  • Lymphocyte telomere length is long in BRCA1 and BRCA2 mutation carriers regardless of cancer-affected status - Pooley, K.A., McGuffog, L., Barrowdale, D., Frost, D., Ellis, S.D., Fineberg, E., Platte, R., Izatt, L., Adlard, J., Bardwell, J., Brewer, C., Cole, T., Cook, J., Davidson, R., Donaldson, A., Dorkins, H., Douglas, F., Eason, J., Houghton, C., Kennedy, M.J., McCann, E., Miedzybrodzka, Z., Murray, A., Porteous, M.E., Rogers, M.T., Side, L.E., Tischkowitz, M., Walker, L., Hodgson, S., Eccles, D.M., Morrison, P. J., Evans, D.G., Eeles, R.A., Antoniou, A.C., Easton, D.F. and Dunning, A.M.
    Published:
    2014
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    23, (6)
    Page Range:
    1018-1024
    doi:
    10.1158/1055-9965.EPI-13-0635-T
    PMID:
    24642354
  • 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy - Li, Jingmei, Lindström, Linda S., Foo, Jia N., Rafiq, Sajjad, Schmidt, Marjanka K., Pharoah, Paul D. P., Michailidou, Kyriaki, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Van ‘t Veer, Laura J., Cornelissen, Sten, Rutgers, Emiel, Southey, Melissa C., Apicella, Carmel, Dite, Gillian S., Hopper, John L., Fasching, Peter A., Haeberle, Lothar, Ekici, Arif B., Beckmann, Matthias W., Blomqvist, Carl, Muranen, Taru A., Aittomäki, Kristiina, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Hartikainen, Jaana M., Kataja, Vesa, Chenevix-Trench, Georgia, Investigators, kConFab, Phillips, Kelly-Anne, McLachlan, Sue-Anne, Lambrechts, Diether, Thienpont, Bernard, Smeets, Ann, Wildiers, Hans, Chang-Claude, Jenny, Flesch-Janys, Dieter, Seibold, Petra, Rudolph, Anja, Giles, Graham G., Baglietto, Laura, Severi, Gianluca, Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick, Le Marchand, Loic, Kristensen, Vessela, Alnæs, Grethe I. Grenaker, Borresen-Dale, Anne-Lise, Nord, Silje, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Devilee, Peter, Tollenaar, Robert, Seynaeve, Caroline, Hooning, Maartje, Kriege, Mieke, Hollestelle, Antoinette, van den Ouweland, Ans, Li, Yi, Hamann, Ute, Torres, Diana, Ulmer, Hans U., Rüdiger, Thomas, Shen, Chen-Yang, Hsiung, Chia-Ni, Wu, Pei-Ei, Chen, Shou-Tung, Teo, Soo Hwang, Taib, Nur Aishah Mohd, Har Yip, Cheng, Fuang Ho, Gwo, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Tajima, Kazuo, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K., Yoo, Keun-Young, Maishman, Tom, Tapper, William J., Dunning, Alison, Shah, Mitul, Luben, Robert, Brown, Judith, Chuen Khor, Chiea, Eccles, Diana M., Nevanlinna, Heli, Easton, Douglas, Humphreys, Keith, Liu, Jianjun, Hall, Per and Czene, Kamila
    Published:
    2014
    Publication:
    Nature Communications
    Volume:
    5
    Page Range:
    4051-[9pp]
    doi:
    10.1038/ncomms5051
  • DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers - Horwitz, Marshall S., Osorio, Ana, Milne, Roger L., Kuchenbaecker, Karoline, Vaclová, Tereza, Pita, Guillermo, Alonso, Rosario, Peterlongo, Paolo, Blanco, Ignacio, de la Hoya, Miguel, Duran, Mercedes, Díez, Orland, Ramón y Cajal, Teresa, Konstantopoulou, Irene, Martínez-Bouzas, Cristina, Andrés Conejero, Raquel, Soucy, Penny, McGuffog, Lesley, Barrowdale, Daniel, Lee, Andrew, Arver, Brita, Rantala, Johanna, Loman, Niklas, Ehrencrona, Hans, Olopade, Olufunmilayo I., Beattie, Mary S., Domchek, Susan M., Nathanson, Katherine, Rebbeck, Timothy R., Arun, Banu K., Karlan, Beth Y., Walsh, Christine, Lester, Jenny, John, Esther M., Whittemore, Alice S., Daly, Mary B., Southey, Melissa, Hopper, John, Terry, Mary B., Buys, Saundra S., Janavicius, Ramunas, Dorfling, Cecilia M., van Rensburg, Elizabeth J., Steele, Linda, Neuhausen, Susan L., Ding, Yuan Chun, Hansen, Thomas v. O., Jønson, Lars, Ejlertsen, Bent, Gerdes, Anne-Marie, Infante, Mar, Herráez, Belén, Moreno, Leticia Thais, Weitzel, Jeffrey N., Herzog, Josef, Weeman, Kisa, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Scuvera, Giulietta, Bonanni, Bernardo, Mariette, Frederique, Volorio, Sara, Viel, Alessandra, Varesco, Liliana, Papi, Laura, Ottini, Laura, Tibiletti, Maria Grazia, Radice, Paolo, Yannoukakos, Drakoulis, Garber, Judy, Ellis, Steve, Frost, Debra, Platte, Radka, Fineberg, Elena, Evans, Gareth, Lalloo, Fiona, Izatt, Louise, Eeles, Ros, Adlard, Julian, Davidson, Rosemarie, Cole, Trevor, Eccles, Diana, Cook, Jackie, Hodgson, Shirley, Brewer, Carole, Tischkowitz, Marc, Douglas, Fiona, Porteous, Mary, Side, Lucy, Walker, Lisa, Morrison, Patrick, Donaldson, Alan, Kennedy, John, Foo, Claire, Godwin, Andrew K., Schmutzler, Rita Katharina, Wappenschmidt, Barbara, Rhiem, Kerstin, Engel, Christoph, Meindl, Alfons, Ditsch, Nina, Arnold, Norbert, Plendl, Hans Jörg, Niederacher, Dieter, Sutter, Christian, Wang-Gohrke, Shan, Steinemann, Doris, Preisler-Adams, Sabine, Kast, Karin, Varon-Mateeva, Raymonda, Gehrig, Andrea, Stoppa-Lyonnet, Dominique, Sinilnikova, Olga M., Mazoyer, Sylvie, Damiola, Francesca, Poppe, Bruce, Claes, Kathleen, Piedmonte, Marion, Tucker, Kathy, Backes, Floor, Rodríguez, Gustavo, Brewster, Wendy, Wakeley, Katie, Rutherford, Thomas, Caldés, Trinidad, Nevanlinna, Heli, Aittomäki, Kristiina, Rookus, Matti A., van Os, Theo A. M., van der Kolk, Lizet, de Lange, J. L., Meijers-Heijboer, Hanne E. J., van der Hout, A. H., van Asperen, Christi J., Gómez Garcia, Encarna B., Hoogerbrugge, Nicoline, Collée, J. Margriet, van Deurzen, Carolien H. M., van der Luijt, Rob B., Devilee, Peter, HEBON, , Olah, Edith, Lázaro, Conxi, Teulé, Alex, Menéndez, Mireia, Jakubowska, Anna, Cybulski, Cezary, Gronwald, Jacek, Lubinski, Jan, Durda, Katarzyna, Jaworska-Bieniek, Katarzyna, Johannsson, Oskar Th., Maugard, Christine, Montagna, Marco, Tognazzo, Silvia, Teixeira, Manuel R., Healey, Sue, Investigators, kConFab, Olswold, Curtis, Guidugli, Lucia, Lindor, Noralane, Slager, Susan, Szabo, Csilla I., Vijai, Joseph, Robson, Mark, Kauff, Noah, Zhang, Liying, Rau-Murthy, Rohini, Fink-Retter, Anneliese, Singer, Christian F., Rappaport, Christine, Geschwantler Kaulich, Daphne, Pfeiler, Georg, Tea, Muy-Kheng, Berger, Andreas, Phelan, Catherine M., Greene, Mark H., Mai, Phuong L., Lejbkowicz, Flavio, Andrulis, Irene, Mulligan, Anna Marie, Glendon, Gord, Toland, Amanda Ewart, Bojesen, Anders, Pedersen, Inge Sokilde, Sunde, Lone, Thomassen, Mads, Kruse, Torben A., Jensen, Uffe Birk, Friedman, Eitan, Laitman, Yael, Shimon, Shani Paluch, Simard, Jacques, Easton, Douglas F., Offit, Kenneth, Couch, Fergus J., Chenevix-Trench, Georgia, Antoniou, Antonis C. and Benitez, Javier
    Published:
    2014
    Publication:
    PLoS Genetics
    Volume:
    10, (4)
    Page Range:
    e1004256-[12pp]
    doi:
    10.1371/journal.pgen.1004256
    PMID:
    24698998
  • Mammographic surveillance in women aged 35–39 at enhanced familial risk of breast cancer (FH02) - Evans, D.G., Thomas, S., Caunt, J., Roberts, L., Howell, A., Wilson, M., Fox, R., Sibbering, D.M., Moss, S., Wallis, M.G., Eccles, D.M. and Duffy, S.
    Published:
    2014
    Publication:
    Familial Cancer
    Volume:
    13, (1)
    Page Range:
    13-21
    doi:
    10.1007/s10689-013-9661-8
    PMID:
    23733252
  • Risk of ovarian cancer and the NF- B pathway: genetic association with IL1A and TNFSF10 - Charbonneau, B., Block, M.S., Bamlet, W.R., Vierkant, R.A., Kalli, K.R., Fogarty, Z., Rider, D.N., Sellers, T.A., Tworoger, S.S., Poole, E., Risch, H.A., Salvesen, H.B., Kiemeney, L.A., Baglietto, L., Giles, G.G., Severi, G., Trabert, B., Wentzensen, N., Chenevix-Trench, G., Whittemore, A.S., Sieh, W., Chang-Claude, J., Bandera, E.V., Orlow, I., Terry, K., Goodman, M.T., Thompson, P.J., Cook, L.S., Rossing, M.A., Ness, R.B., Narod, S.A., Kupryjanczyk, J., Lu, K., Butzow, R., Dork, T., Pejovic, T., Campbell, I., Le, N.D., Bunker, C.H., Bogdanova, N., Runnebaum, I.B., Eccles, D., Paul, J., Wu, A.H., Gayther, S.A., Hogdall, E., Heitz, F., Kaye, S.B., Karlan, B.Y., Anton-Culver, H., Gronwald, J., Hogdall, C.K., Lambrechts, D., Fasching, P.A., Menon, U., Schildkraut, J., Pearce, C.L., Levine, D.A., Kjaer, S.K., Cramer, D., Flanagan, J.M., Phelan, C.M., Brown, R., Massuger, L.F.A.G., Song, H., Doherty, J.A., Krakstad, C., Liang, D., Odunsi, K., Berchuck, A., Jensen, A., Lubinski, J., Nevanlinna, H., Bean, Y.T., Lurie, G., Ziogas, A., Walsh, C., Despierre, E., Brinton, L., Hein, A., Rudolph, A., Dansonka-Mieszkowska, A., Olson, S.H., Harter, P., Tyrer, J., Vitonis, A.F., Brooks-Wilson, A., Aben, K.K., Pike, M.C., Ramus, S.J., Wik, E., Cybulski, C., Lin, J., Sucheston, L., Edwards, R., McGuire, V., Lester, J., du Bois, A., Lundvall, L., Wang-Gohrke, S., Szafron, L.M., Lambrechts, S., Yang, H., Beckmann, M.W., Pelttari, L.M., Van Altena, A.M., van den Berg, D., Halle, M.K., Gentry-Maharaj, A., Schwaab, I., Chandran, U., Menkiszak, J., Ekici, A.B., Wilkens, L.R., Leminen, A., Modugno, F., Friel, G., Rothstein, J.H., Vergote, I., Garcia-Closas, M., Hildebrandt, M.A.T., Sobiczewski, P., Kelemen, L.E., Pharoah, P.D.P., Moysich, K., Knutson, K.L., Cunningham, J.M., Fridley, B.L. and Goode, E.L.
    Published:
    2014
    Publication:
    Cancer Research
    Volume:
    74, (3)
    Page Range:
    852-861
    doi:
    10.1158/0008-5472.CAN-13-1051
    PMID:
    24272484
  • Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome - Charbonneau, B., Moysich, K.B., Kalli, K.R., Oberg, A.L., Vierkant, R.A., Fogarty, Z.C., Block, M.S., Maurer, M.J., Goergen, K.M., Fridley, B.L., Cunningham, J.M., Rider, D.N., Preston, C., Hartmann, L.C., Lawrenson, K., Wang, C., Tyrer, J., Song, H., deFazio, A., Johnatty, S.E., Doherty, J.A., Phelan, C.M., Sellers, T.A., Ramirez, S.M., Vitonis, A.F., Terry, K.L., Van Den Berg, D., Pike, M.C., Wu, A.H., Berchuck, A., Gentry-Maharaj, A., Ramus, S.J., Diergaarde, B., Shen, H., Jensen, A., Menkiszak, J., Cybulski, C., Lubi ski, J., Ziogas, A., Rothstein, J.H., McGuire, V., Sieh, W., Lester, J., Walsh, C., Vergote, I., Lambrechts, S., Despierre, E., Garcia-Closas, M., Yang, H., Brinton, L.A., Spiewankiewicz, B., Rzepecka, I.K., Dansonka-Mieszkowska, A., Seibold, P., Rudolph, A., Paddock, L.E., Orlow, I., Lundvall, L., Olson, S.H., Hogdall, C.K., Schwaab, I., du Bois, A., Harter, P., Flanagan, J.M., Brown, R., Paul, J., Ekici, A.B., Beckmann, M.W., Hein, A., Eccles, D., Lurie, G., Hays, L.E., Bean, Y.T., Pejovic, T., Goodman, M.T., Campbell, I., Fasching, P.A., Konecny, G., Kaye, S.B., Heitz, F., Hogdall, E., Bandera, E.V., Chang-Claude, J., Kupryjanczyk, J., Wentzensen, N., Lambrechts, D., Karlan, B.Y., Whittemore, A.S., Culver, H.A., Gronwald, J., Levine, D.A., Kjaer, S.K., Menon, U., Schildkraut, J.M., Pearce, C.L., Cramer, D.W., Rossing, M.A., Chenevix-Trench, G., Pharoah, P.D.P., Gayther, S.A., Ness, R.B., Odunsi, K., Sucheston, L.E., Knutson, K.L. and Goode, E.L.
    Published:
    2014
    Publication:
    Cancer Immunology Research
    Volume:
    2, (4)
    Page Range:
    332-340
    doi:
    10.1158/2326-6066.CIR-13-0136
    PMID:
    24764580
  • Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA - Earp, Madalene A., Kelemen, Linda E., Magliocco, Anthony M., Swenerton, Kenneth D., Chenevix-Trench, Georgia, Lu, Yi, Hein, Alexander, Ekici, Arif B., Beckmann, Matthias W., Fasching, Peter A., Lambrechts, Diether, Despierre, Evelyn, Vergote, Ignace, Lambrechts, Sandrina, Doherty, Jennifer A., Rossing, Mary Anne, Chang-Claude, Jenny, Rudolph, Anja, Friel, Grace, Moysich, Kirsten B., Odunsi, Kunle, Sucheston-Campbell, Lara, Lurie, Galina, Goodman, Marc T., Carney, Michael E., Thompson, Pamela J., Runnebaum, Ingo B., Dürst, Matthias, Hillemanns, Peter, Dörk, Thilo, Antonenkova, Natalia, Bogdanova, Natalia, Leminen, Arto, Nevanlinna, Heli, Pelttari, Liisa M., Butzow, Ralf, Bunker, Clareann H., Modugno, Francesmary, Edwards, Robert P., Ness, Roberta B., du Bois, Andreas, Heitz, Florian, Schwaab, Ira, Harter, Philipp, Karlan, Beth Y., Walsh, Christine, Lester, Jenny, Jensen, Allan, Kjær, Susanne K., Høgdall, Claus K., Høgdall, Estrid, Lundvall, Lene, Sellers, Thomas A., Fridley, Brooke L., Goode, Ellen L., Cunningham, Julie M., Vierkant, Robert A., Giles, Graham G., Baglietto, Laura, Severi, Gianluca, Southey, Melissa C., Liang, Dong, Wu, Xifeng, Lu, Karen, Hildebrandt, Michelle A.T., Levine, Douglas A., Bisogna, Maria, Schildkraut, Joellen M., Iversen, Edwin S., Weber, Rachel Palmieri, Berchuck, Andrew, Cramer, Daniel W., Terry, Kathryn L., Poole, Elizabeth M., Tworoger, Shelley S., Bandera, Elisa V., Chandran, Urmila, Orlow, Irene, Olson, Sara H., Wik, Elisabeth, Salvesen, Helga B., Bjorge, Line, Halle, Mari K., van Altena, Anne M., Aben, Katja K. H., Kiemeney, Lambertus A., Massuger, Leon F.A.G., Pejovic, Tanja, Bean, Yukie T., Cybulski, Cezary, Gronwald, Jacek, Lubinski, Jan, Wentzensen, Nicolas, Brinton, Louise A., Lissowska, Jolanta, Garcia-Closas, Montserrat, Dicks, Ed, Dennis, Joe, Easton, Douglas F., Song, Honglin, Tyrer, Jonathan P., Pharoah, Paul D. P., Eccles, Diana, Campbell, Ian G., Whittemore, Alice S., McGuire, Valerie, Sieh, Weiva, Rothstein, Joseph H., Flanagan, James M., Paul, James, Brown, Robert, Phelan, Catherine M., Risch, Harvey A., McLaughlin, John R., Narod, Steven A., Ziogas, Argyrios, Anton-Culver, Hoda, Gentry-Maharaj, Aleksandra, Menon, Usha, Gayther, Simon A., Ramus, Susan J., Wu, Anna H., Pearce, Celeste L., Pike, Malcolm C., Dansonka-Mieszkowska, Agnieszka, Rzepecka, Iwona K., Szafron, Lukasz M., Kupryjanczyk, Jolanta, Cook, Linda S., Le, Nhu D. and Brooks-Wilson, Angela
    Published:
    2014
    Publication:
    Human Genetics
    Volume:
    133, (5)
    Page Range:
    481-497
    doi:
    10.1007/s00439-013-1383-3
    PMID:
    24190013
  • Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer - Purrington, K.S., Slager, S., Eccles, D., Yannoukakos, D., Fasching, P.A., Miron, P., Carpenter, J., Chang-Claude, J., Martin, N.G., Montgomery, G.W., Kristensen, V., Anton-Culver, H., Goodfellow, P., Tapper, W.J., Rafiq, S., Gerty, S.M., Durcan, L., Konstantopoulou, I., Fostira, F., Vratimos, A., Apostolou, P., Konstanta, I., Kotoula, V., Lakis, S., Dimopoulos, M.A., Skarlos, D., Pectasides, D., Fountzilas, G., Beckmann, M.W., Hein, A., Ruebner, M., Ekici, A.B., Hartmann, A., Schulz-Wendtland, R., Renner, S.P., Janni, W., Rack, B., Scholz, C., Neugebauer, J., Andergassen, U., Lux, M.P., Haeberle, L., Clarke, C., Pathmanathan, N., Rudolph, A., Flesch-Janys, D., Nickels, S., Olson, J.E., Ingle, J.N., Olswold, C., Slettedahl, S., Eckel-Passow, J.E., Anderson, S.K., Visscher, D.W., Cafourek, V.L., Sicotte, H., Prodduturi, N., Weiderpass, E., Bernstein, L., Ziogas, A., Ivanovich, J., Giles, G.G., Baglietto, L., Southey, M., Kosma, V.-M., Fischer, H.-P., Reed, M.W.R., Cross, S.S., Deming-Halverson, S., Shrubsole, M., Cai, Q., Shu, X.-O., Daly, M., Weaver, J., Ross, E., Klemp, J., Sharma, P., Torres, D., Rudiger, T., Wolfing, H., Ulmer, H.-U., Forsti, A., Khoury, T., Kumar, S., Pilarski, R., Shapiro, C.L., Greco, D., Heikkila, P., Aittomaki, K., Blomqvist, C., Irwanto, A., Liu, J., Pankratz, V.S., Wang, X., Severi, G., Mannermaa, A., Easton, D., Hall, P., Brauch, H., Cox, A., Zheng, W., Godwin, A.K., Hamann, U., Ambrosone, C., Toland, A.E., Nevanlinna, H., Vachon, C.M. and Couch, F.J.
    Published:
    2014
    Publication:
    Carcinogenesis
    Volume:
    35, (5)
    Page Range:
    1012-1019
    doi:
    10.1093/carcin/bgt404
    PMID:
    24325915
  • Comment on : Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer - Taneja, S.S., Castro, E., Goh, C., Olmos, D., Saunders, E., Leongamornlert, D., Tymrakiewicz, M., Mahmud, N., Dadaev, T., Govindasami, K., Guy, M., Sawyer, E., Wilkinson, R., Ardern-Jones, A., Ellis, S., Frost, D., Peock, S., Evans, D.G., Tischkowitz, M., Cole, T., Davidson, R., Eccles, D., Brewer, C., Douglas, F., Porteous, M.E., Donaldson, A., Dorkins, H., Izatt, L., Hodgson, S., Cook, J., Kennedy, M.J., Murray, A., Side, L.E., Eason, J., Antoniou, A.C., Easton, D.F., Kote-Jarai, Z. and Eeles, R.
    Published:
    2013
    Publication:
    The Journal of Urology
    Volume:
    190, (6)
    Page Range:
    2093-2094
    doi:
    10.1016/j.juro.2013.08.101
    PMID:
    24209519
  • Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study - Copson, E., Maishman, T., Gerty, S., Eccles, B., Stanton, L., Cutress, R .I., Altman, D.G., Durcan, L., Simmonds, P., Jones, L., Tapper, W. and Eccles, Diana
    Published:
    2013
    Publication:
    British Journal of Cancer
    Page Range:
    1-12
    doi:
    10.1038/bjc.2013.650
  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer - Eccles, Suzanne A., Aboagye, Eric O., Ali, Simak, Anderson, Annie S., Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P., Brennan, Keith, Brown, Nicola J., Bryant, Helen E., Bundred, Nigel J., Burchell, Joy M., Campbell, Anna M., Carroll, Jason S., Clarke, Robert B., Coles, Charlotte E., Cook, Gary J.R., Cox, Angela, Curtin, Nicola J., Dekker, Lodewijk V., dos Santos Silva, Isabel, Duffy, Stephen W., Easton, Douglas F., Eccles, Diana M., Edwards, Dylan R., Edwards, Joanne, Evans, D. Gareth, Fenlon, Deborah F., Flanagan, James M., Foster, Claire, Gallagher, William M., Garcia-Closas, Montserrat, Gee, Julia M.W., Gescher, Andy J., Goh, Vicky, Groves, Ashley M., Harvey, Amanda J., Harvie, Michelle, Hennessy, Bryan T., Hiscox, Stephen, Holen, Ingunn, Howell, Sacha J., Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S., Jasani, Bharat, Jones, Louise J., Key, Timothy J., Kirwan, Cliona C., Kong, Anthony, Kunkler, Ian H., Langdon, Simon P., Leach, Martin O., Mann, David J., Marshall, John F., Martin, Lesley Ann, Martin, Stewart G., Macdougall, Jennifer E., Miles, David W., Miller, William R., Morris, Joanna R., Moss, Sue M., Mullan, Paul, Natrajan, Rachel, O’Connor, James P.B., O’Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D.P., Rakha, Emad A., Reed, Elizabeth, Robinson, Simon P., Sahai, Erik, Saxton, John M., Schmid, Peter, Smalley, Matthew J., Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H., Tutt, Andrew N. J., Velikova, Galina, Walker, Rosemary A., Watson, Christine J., Williams, Kaye J., Young, Leonie S. and Thompson, Alastair M.
    Published:
    2013
    Publication:
    Breast Cancer Research
    Volume:
    15, (5)
    Page Range:
    1-37
    doi:
    10.1186/bcr3493
    PMID:
    24286369
  • Support vector machine classifier for estrogen receptor positive and negative early-onset breast cancer - Upstill-Goddard, R., Eccles, Diana, Ennis, Sarah, Rafiq, Sajjad, Tapper, William, Fliege, Jörg and Collins, Andrew
    Published:
    2013
    Publication:
    PLoS ONE
    Volume:
    8, (7)
    Page Range:
    e68606
    doi:
    10.1371/journal.pone.0068606
  • Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men - Killick, Emma, Morgan, Richard, Launchbury, Francesca, Bancroft, Elizabeth, Page, Elizabeth, Castro, Elena, Kote-Jarai, Zsofia, Aprikian, Armen, Blanco, Ignacio, Clowes, Virginia, Domchek, Susan, Douglas, Fiona, Eccles, Diana, Evans, D. Gareth, Harris, Marion, Kirk, Judy, Lam, Jimmy, Lindeman, Geoffrey, Mitchell, Gillian, Pachter, Nicholas, Selkirk, Christina, Tucker, Kathy, Zgajnar, Janaz, Eeles, Rosalind and Pandha, Hardev
    Published:
    2013
    Publication:
    Scientific Reports
    Volume:
    3
    Page Range:
    2059-[5pp]
    doi:
    10.1038/srep02059
    PMID:
    23792811
  • Prospective Observational Study of Breast Cancer Treatment Outcomes for UK Women Aged 18–40 Years at Diagnosis: The POSH Study - Copson, Ellen, Eccles, Bryony, Maishman, Tom, Gerty, Sue, Stanton, L., Cutress, Ramsey I., Altman, Douglas G., Durcan, Lorraine, Simmonds, Peter, Lawrence, Gill, Jones, Louise, Bliss, Judith and Eccles, Diana
    Published:
    2013
    Publication:
    JNCI Journal of the National Cancer Institute
    Volume:
    105, (13)
    Page Range:
    978-988
    doi:
    10.1093/jnci/djt134
    PMID:
    23723422
  • Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer - Castro, E., Goh, C., Olmos, D., Saunders, E., Leongamornlert, D., Tymrakiewicz, M., Mahmud, N., Dadaev, T., Govindasami, K., Guy, M., Sawyer, E., Wilkinson, R., Ardern-Jones, A., Ellis, S., Frost, D., Peock, S., Evans, D.G., Tischkowitz, M., Cole, T., Davidson, R., Eccles, D., Brewer, C., Douglas, F., Porteous, M.E., Donaldson, A., Dorkins, H., Izatt, L., Cook, J., Hodgson, S., Kennedy, M.J., Side, L.E., Eason, J., Murray, A., Antoniou, A.C., Easton, D.F., Kote-Jarai, Z. and Eeles, R.
    Published:
    2013
    Publication:
    Journal of Clinical Oncology
    Volume:
    31, (14)
    Page Range:
    1748-1757
    doi:
    10.1200/JCO.2012.43.1882
    PMID:
    23569316
  • Analysis of over 10,000 cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome - White, K.L., Vierkant, R.A., Fogarty, Z.C., Charbonneau, B., Block, M.S., Pharoah, P.D.P., Chenevix-Trench, G., Rossing, M.A., Cramer, D.W., Pearce, C.L., Schildkraut, J.M., Menon, U., Kjaer, S.K., Levine, D.A., Gronwald, J., Culver, H.A., Whittemore, A.S., Karlan, B.Y., Lambrechts, D., Wentzensen, N., Kupryjanczyk, J., Chang-Claude, J., Bandera, E.V., Hogdall, E., Heitz, F., Kaye, S.B., Fasching, P.A., Campbell, I., Goodman, M.T., Pejovic, T., Bean, Y., Lurie, G., Eccles, D., Hein, A., Beckmann, M.W., Ekici, A.B., Paul, J., Brown, R., Flanagan, J.M., Harter, P., du Bois, A., Schwaab, I., Hogdall, C.K., Lundvall, L., Olson, S.H., Orlow, I., Paddock, L.E., Rudolph, A., Eilber, U., Dansonka-Mieszkowska, A., Rzepecka, I.K., Ziolkowska-Seta, I., Brinton, L., Yang, H., Garcia-Closas, M., Despierre, E., Lambrechts, S., Vergote, I., Walsh, C., Lester, J., Sieh, W., McGuire, V., Rothstein, J.H., Ziogas, A., Lubinski, J., Cybulski, C., Menkiszak, J., Jensen, A., Gayther, S.A., Ramus, S.J., Gentry-Maharaj, A., Berchuck, A., Wu, A.H., Pike, M.C., Van DenBerg, D., Terry, K.L., Vitonis, A.F., Doherty, J.A., Johnatty, S.E., deFazio, A., Song, H., Tyrer, J., Sellers, T.A., Phelan, C.M., Kalli, K.R., Cunningham, J.M., Fridley, B.L. and Goode, E.L.
    Published:
    2013
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    22, (5)
    Page Range:
    987-992
    doi:
    10.1158/1055-9965.EPI-13-0028
    PMID:
    23513043
  • Information required for surgical decision making in young women with breast cancer - Recio, Alejandra, Gerty, Sue, Foster, Claire, Cutress, R.I. and Eccles, Diana
    Published:
    2013
    Publication:
    European Journal of Surgical Oncology (EJSO)
    Volume:
    39, (5)
    Page Range:
    498
    doi:
    10.1016/j.ejso.2013.01.168
  • Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE - Mavaddat, N., Peock, S., Frost, D., Ellis, S., Platte, R., Fineberg, E., Evans, D.G., Izatt, L., Eeles, R.A., Adlard, J., Davidson, R., Eccles, D., Cole, T., Cook, J., Brewer, C., Tischkowitz, M., Douglas, F., Hodgson, S., Walker, L., Porteous, M.E., Morrison, P.J., Side, L.E., Kennedy, M.J., Houghton, C., Donaldson, A., Rogers, M.T., Dorkins, H., Miedzybrodzka, Z., Gregory, H., Eason, J., Barwell, J., McCann, E., Murray, A., Antoniou, A.C. and Easton, D.F.
    Published:
    2013
    Publication:
    JNCI Journal of the National Cancer Institute
    doi:
    10.1093/jnci/djt095
  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer - Pharoah, Paul D.P., Tsai, Ya-Yu, Ramus, Susan J., Phelan, Catherine M., Goode, Ellen L., Lawrenson, Kate, Buckley, Melissa, Fridley, Brooke L., Tyrer, Jonathan P., Shen, Howard, Weber, Rachel, Karevan, Rod, Larson, Melissa C., Song, Honglin, Tessier, Daniel C., Bacot, François, Vincent, Daniel, Cunningham, Julie M., Dennis, Joe, Dicks, Ed, Aben, Katja K, Anton-Culver, Hoda, Antonenkova, Natalia, Armasu, Sebastian M., Baglietto, Laura, Bandera, Elisa V., Beckmann, Matthias W., Birrer, Michael J., Bloom, Greg, Bogdanova, Natalia, Brenton, James D., Brinton, Louise A., Brooks-Wilson, Angela, Brown, Robert, Butzow, Ralf, Campbell, Ian, Carney, Michael E., Carvalho, Renato S., Chang-Claude, Jenny, Chen, Y. Anne, Chen, Zhihua, Chow, Wong-Ho, Cicek, Mine S., Coetzee, Gerhard, Cook, Linda S., Cramer, Daniel W., Cybulski, Cezary, Dansonka-Mieszkowska, Agnieszka, Despierre, Evelyn, Doherty, Jennifer A., Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Eccles, Diana, Edwards, Robert, Ekici, Arif B., Fasching, Peter A., Fenstermacher, David, Flanagan, James, Gao, Yu-Tang, Garcia-Closas, Montserrat, Gentry-Maharaj, Aleksandra, Giles, Graham, Gjyshi, Anxhela, Gore, Martin, Gronwald, Jacek, Guo, Qi, Halle, Mari K., Harter, Philipp, Hein, Alexander, Heitz, Florian, Hillemanns, Peter, Hoatlin, Maureen, Høgdall, Estrid, Høgdall, Claus K., Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Kalli, Kimberly R., Karlan, Beth Y., Kelemen, Linda E., Kiemeney, Lambertus A., Kjaer, Susanne Krüger, Konecny, Gottfried E., Krakstad, Camilla, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Le, Nhu D., Lee, Nathan, Lee, Janet, Leminen, Arto, Lim, Boon Kiong, Lissowska, Jolanta, Lubiński, Jan, Lundvall, Lene, Lurie, Galina, Massuger, Leon F.A G., Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R., Menon, Usha, Modugno, Francesmary, Moysich, Kirsten B., Nakanishi, Toru, Narod, Steven A., Ness, Roberta B., Nevanlinna, Heli, Nickels, Stefan, Noushmehr, Houtan, Odunsi, Kunle, Olson, Sara, Orlow, Irene, Paul, James, Pejovic, Tanja, Pelttari, Liisa M., Permuth-Wey, Jenny, Pike, Malcolm C., Poole, Elizabeth M., Qu, Xiaotao, Risch, Harvey A., Rodriguez-Rodriguez, Lorna, Rossing, Mary Anne, Rudolph, Anja, Runnebaum, Ingo, Rzepecka, Iwona K., Salvesen, Helga B., Schwaab, Ira, Severi, Gianluca, Shen, Hui, Shridhar, Vijayalakshmi, Shu, Xiao-Ou, Sieh, Weiva, Southey, Melissa C., Spellman, Paul, Tajima, Kazuo, Teo, Soo-Hwang, Terry, Kathryn L., Thompson, Pamela J., Timorek, Agnieszka, Tworoger, Shelley S., van Altena, Anne M., van den Berg, David, Vergote, Ignace, Vierkant, Robert A., Vitonis, Allison F, Wang-Gohrke, Shan, Wentzensen, Nicolas, Whittemore, Alice S., Wik, Elisabeth, Winterhoff, Boris, Woo, Yin Ling, Wu, Anna H., Yang, Hannah P., Zheng, Wei, Ziogas, Argyrios, Zulkifli, Famida, Goodman, Marc T., Hall, Per, Easton, Douglas F., Pearce, Celeste L., Berchuck, Andrew, Chenevix-Trench, Georgia, Iversen, Edwin, Monteiro, Alvaro N.A., Gayther, Simon A., Schildkraut, Joellen M. and Sellers, Thomas A.
    Published:
    2013
    Publication:
    Nature Genetics
    Volume:
    45, (4)
    Page Range:
    362-370
    doi:
    10.1038/ng.2564
    PMID:
    23535730
  • Genome-wide association studies identify four ER negative–specific breast cancer risk loci - Garcia-Closas, Montserrat, Couch, Fergus J., Lindstrom, Sara, Michailidou, Kyriaki, Schmidt, Marjanka K., Brook, Mark N., Orr, Nick, Rhie, Suhn Kyong, Riboli, Elio, Feigelson, Heather S., Le Marchand, Loic, Buring, Julie E., Eccles, Diana, Miron, Penelope, Fasching, Peter A., Brauch, Hiltrud, Chang-Claude, Jenny, Carpenter, Jane, Godwin, Andrew K., Nevanlinna, Heli, Giles, Graham G., Cox, Angela, Hopper, John L., Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Dicks, Ed, Howat, Will J., Schoof, Nils, Bojesen, Stig E., Lambrechts, Diether, Broeks, Annegien, Andrulis, Irene L., Guénel, Pascal, Burwinkel, Barbara, Sawyer, Elinor J., Hollestelle, Antoinette, Fletcher, Olivia, Winqvist, Robert, Brenner, Hermann, Mannermaa, Arto, Hamann, Ute, Meindl, Alfons, Lindblom, Annika, Zheng, Wei, Devillee, Peter, Goldberg, Mark S., Lubinski, Jan, Kristensen, Vessela, Swerdlow, Anthony, Anton-Culver, Hoda, Dörk, Thilo, Muir, Kenneth, Matsuo, Keitaro, Wu, Anna H., Radice, Paolo, Teo, Soo Hwang, Shu, Xiao-Ou, Blot, William, Kang, Daehee, Hartman, Mikael, Sangrajrang, Suleeporn, Shen, Chen-Yang, Southey, Melissa C., Park, Daniel J., Hammet, Fleur, Stone, Jennifer, Veer, Laura J. Van't, Rutgers, Emiel J., Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Peto, Julian, Schrauder, Michael G., Ekici, Arif B., Beckmann, Matthias W., dos Santos Silva, Isabel, Johnson, Nichola, Warren, Helen, Tomlinson, Ian, Kerin, Michael J, Miller, Nicola, Marme, Federick, Schneeweiss, Andreas, Sohn, Christof, Truong, Therese, Laurent-Puig, Pierre, Kerbrat, Pierre, Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Milne, Roger L., Perez, Jose Ignacio Arias, Menéndez, Primitiva, Müller, Heiko, Arndt, Volker, Stegmaier, Christa, Lichtner, Peter, Lochmann, Magdalena, Justenhoven, Christina, Ko, Yon-Dschun, Muranen, Taru A., Aittomäki, Kristiina, Blomqvist, Carl, Greco, Dario, Heikkinen, Tuomas, Ito, Hidemi, Iwata, Hiroji, Yatabe, Yasushi, Antonenkova, Natalia N., Margolin, Sara, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Balleine, Rosemary, Tseng, Chiu-Chen, Berg, David Van Den, Stram, Daniel O., Neven, Patrick, Dieudonné, Anne-Sophie, Leunen, Karin, Rudolph, Anja, Nickels, Stefan, Flesch-Janys, Dieter, Peterlongo, Paolo, Peissel, Bernard, Bernard, Loris, Olson, Janet E., Wang, Xianshu, Stevens, Kristen, Severi, Gianluca, Baglietto, Laura, McLean, Catriona, Coetzee, Gerhard A., Feng, Ye, Henderson, Brian E., Schumacher, Fredrick, Bogdanova, Natalia V., Labrèche, France, Dumont, Martine, Yip, Cheng Har, Taib, Nur Aishah Mohd, Cheng, Ching-Yu, Shrubsole, Martha, Long, Jirong, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Kauppila, Saila, Knight, Julia A., Glendon, Gord, Mulligan, Anna Marie, Tollenaar, Robertus A. E. M., Seynaeve, Caroline M., Kriege, Mieke, Hooning, Maartje J., van den Ouweland, Ans M. W., van Deurzen, Carolien H. M., Lu, Wei, Gao, Yu-Tang, Cai, Hui, Balasubramanian, Sabapathy P., Cross, Simon S., Reed, Malcolm W. R., Signorello, Lisa, Cai, Qiuyin, Shah, Mitul, Miao, Hui, Chan, Ching Wan, Chia, Kee Seng, Jakubowska, Anna, Jaworska, Katarzyna, Durda, Katarzyna, Hsiung, Chia-Ni, Wu, Pei-Ei, Yu, Jyh-Cherng, Ashworth, Alan, Jones, Michael, Tessier, Daniel C., González-Neira, Anna, Pita, Guillermo, Alonso, M. Rosario, Vincent, Daniel, Bacot, Francois, Ambrosone, Christine B., Bandera, Elisa V., John, Esther M., Chen, Gary K., Hu, Jennifer J., Rodriguez-Gil, Jorge L., Bernstein, Leslie, Press, Michael F., Ziegler, Regina G., Millikan, Robert M., Deming-Halverson, Sandra L., Nyante, Sarah, Ingles, Sue A., Waisfisz, Quinten, Tsimiklis, Helen, Makalic, Enes, Schmidt, Daniel, Bui, Minh, Gibson, Lorna, Müller-Myhsok, Bertram, Schmutzler, Rita K., Hein, Rebecca, Dahmen, Norbert, Beckmann, Lars, Aaltonen, Kirsimari, Czene, Kamila, Irwanto, Astrid, Liu, Jianjun, Turnbull, Clare, Rahman, Nazneen, Meijers-Heijboer, Hanne, Uitterlinden, Andre G., Rivadeneira, Fernando, Olswold, Curtis, Slager, Susan, Pilarski, Robert, Ademuyiwa, Foluso, Konstantopoulou, Irene, Martin, Nicholas G., Montgomery, Grant W., Slamon, Dennis J., Rauh, Claudia, Lux, Michael P., Jud, Sebastian M., Bruning, Thomas, Weaver, JoEllen, Sharma, Priyanka, Pathak, Harsh, Tapper, Will, Gerty, Sue, Durcan, Lorraine, Trichopoulos, Dimitrios, Tumino, Rosario, Peeters, Petra H., Kaaks, Rudolf, Campa, Daniele, Canzian, Federico, Weiderpass, Elisabete, Johansson, Mattias, Khaw, Kay-Tee, Travis, Ruth, Clavel-Chapelon, Françoise, Kolonel, Laurence N., Chen, Constance, Beck, Andy, Hankinson, Susan E., Berg, Christine D., Hoover, Robert N., Lissowska, Jolanta, Figueroa, Jonine D., Chasman, Daniel I., Gaudet, Mia M., Diver, W. Ryan, Willett, Walter C., Hunter, David J., Simard, Jacques, Benitez, Javier, Dunning, Alison M., Sherman, Mark E., Chenevix-Trench, Georgia, Chanock, Stephen J., Hall, Per, Pharoah, Paul D. P., Vachon, Celine, Easton, Douglas F., Haiman, Christopher A. and Kraft, Peter
    Published:
    2013
    Publication:
    Nature Genetics
    Volume:
    45, (4)
    Page Range:
    392-398
    doi:
    10.1038/ng.2561
    PMID:
    23535733
  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer - Bojesen, Stig E., Pooley, Karen A., Johnatty, Sharon E., Beesley, Jonathan, Michailidou, Kyriaki, Tyrer, Jonathan P., Edwards, Stacey L., Pickett, Hilda A., Shen, Howard C., Smart, Chanel E., Hillman, Kristine M., Mai, Phuong L., Lawrenson, Kate, Stutz, Michael D., Lu, Yi, Karevan, Rod, Woods, Nicholas, Johnston, Rebecca L., French, Juliet D., Chen, Xiaoqing, Weischer, Maren, Nielsen, Sune F., Maranian, Melanie J., Ghoussaini, Maya, Ahmed, Shahana, Baynes, Caroline, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, McGuffog, Lesley, Barrowdale, Daniel, Lee, Andrew, Healey, Sue, Lush, Michael, Tessier, Daniel C., Vincent, Daniel, Bacot, Françis, Vergote, Ignace, Lambrechts, Sandrina, Despierre, Evelyn, Risch, Harvey A., González-Neira, Anna, Rossing, Mary Anne, Pita, Guillermo, Doherty, Jennifer A., Álvarez, Nuria, Larson, Melissa C., Fridley, Brooke L., Schoof, Nils, Chang-Claude, Jenny, Cicek, Mine S., Peto, Julian, Kalli, Kimberly R., Broeks, Annegien, Armasu, Sebastian M., Schmidt, Marjanka K., Braaf, Linde M., Winterhoff, Boris, Nevanlinna, Heli, Konecny, Gottfried E., Lambrechts, Diether, Rogmann, Lisa, Guénel, Pascal, Teoman, Attila, Milne, Roger L., Garcia, Joaquin J., Cox, Angela, Shridhar, Vijayalakshmi, Burwinkel, Barbara, Marme, Frederik, Hein, Rebecca, Sawyer, Elinor J., Haiman, Christopher A., Wang-Gohrke, Shan, Andrulis, Irene L., Moysich, Kirsten B., Hopper, John L., Odunsi, Kunle, Lindblom, Annika, Giles, Graham G., Brenner, Hermann, Simard, Jacques, Lurie, Galina, Fasching, Peter A., Carney, Michael E., Radice, Paolo, Wilkens, Lynne R., Swerdlow, Anthony, Goodman, Marc T., Brauch, Hiltrud, Garcia-Closas, Montserrat, Hillemanns, Peter, Winqvist, Robert, Dürst, Matthias, Devilee, Peter, Runnebaum, Ingo, Jakubowska, Anna, Lubinski, Jan, Mannermaa, Arto, Butzow, Ralf, Bogdanova, Natalia V, Dörk, Thilo, Pelttari, Liisa M., Zheng, Wei, Leminen, Arto, Anton-Culver, Hoda, Bunker, Clareann H., Kristensen, Vessela, Ness, Roberta B, Muir, Kenneth, Edwards, Robert, Meindl, Alfons, Heitz, Florian, Matsuo, Keitaro, du Bois, Andreas, Wu, Anna H, Harter, Philipp, Teo, Soo-Hwang, Schwaab, Ira, Shu, Xiao-Ou, Blot, William, Hosono, Satoyo, Kang, Daehee, Nakanishi, Toru, Hartman, Mikael, Yatabe, Yasushi, Hamann, Ute, Karlan, Beth Y, Sangrajrang, Suleeporn, Kjaer, Susanne Krüger, Gaborieau, Valerie, Jensen, Allan, Eccles, Diana, Høgdall, Estrid, Shen, Chen-Yang, Brown, Judith, Woo, Yin Ling, Shah, Mitul, Azmi, Mat Adenan Noor, Luben, Robert, Omar, Siti Zawiah, Czene, Kamila, Vierkant, Robert A, Nordestgaard, Børge G, Flyger, Henrik, Vachon, Celine, Olson, Janet E, Wang, Xianshu, Levine, Douglas A, Rudolph, Anja, Weber, Rachel Palmieri, Flesch-Janys, Dieter, Iversen, Edwin, Nickels, Stefan, Schildkraut, Joellen M, Silva, Isabel Dos Santos, Cramer, Daniel W, Gibson, Lorna, Terry, Kathryn L, Fletcher, Olivia, Vitonis, Allison F, van der Schoot, C Ellen, Poole, Elizabeth M, Hogervorst, Frans B L, Tworoger, Shelley S, Liu, Jianjun, Bandera, Elisa V, Li, Jingmei, Olson, Sara H, Humphreys, Keith, Orlow, Irene, Blomqvist, Carl, Rodriguez-Rodriguez, Lorna, Aittomäki, Kristiina, Salvesen, Helga B, Muranen, Taru A, Wik, Elisabeth, Brouwers, Barbara, Krakstad, Camilla, Wauters, Els, Halle, Mari K, Wildiers, Hans, Kiemeney, Lambertus A, Mulot, Claire, Aben, Katja K, Laurent-Puig, Pierre, Altena, Anne Mvan, Truong, Thérèse, Massuger, Leon F A G, Benitez, Javier, Pejovic, Tanja, Perez, Jose Ignacio Arias, Hoatlin, Maureen, Zamora, M Pilar, Cook, Linda S, Balasubramanian, Sabapathy P, Kelemen, Linda E, Schneeweiss, Andreas, Le, Nhu D, Sohn, Christof, Brooks-Wilson, Angela, Tomlinson, Ian, Kerin, Michael J, Miller, Nicola, Cybulski, Cezary, Henderson, Brian E, Menkiszak, Janusz, Schumacher, Fredrick, Wentzensen, Nicolas, Le Marchand, Loic, Yang, Hannah P, Mulligan, Anna Marie, Glendon, Gord, Engelholm, Svend Aage, Knight, Julia A, Høgdall, Claus K, Apicella, Carmel, Gore, Martin, Tsimiklis, Helen, Song, Honglin, Southey, Melissa C, Jager, Agnes, den Ouweland, Ans M Wvan, Brown, Robert, Martens, John W M, Flanagan, James M, Kriege, Mieke, Paul, James, Margolin, Sara, Siddiqui, Nadeem, Severi, Gianluca, Whittemore, Alice S, Baglietto, Laura, McGuire, Valerie, Stegmaier, Christa, Sieh, Weiva, Müller, Heiko, Arndt, Volker, Labrèche, France, Gao, Yu-Tang, Goldberg, Mark S, Yang, Gong, Dumont, Martine, McLaughlin, John R, Hartmann, Arndt, Ekici, Arif B, Beckmann, Matthias W, Phelan, Catherine M, Lux, Michael P, Permuth-Wey, Jenny, Peissel, Bernard, Sellers, Thomas A, Ficarazzi, Filomena, Barile, Monica, Ziogas, Argyrios, Ashworth, Alan, Gentry-Maharaj, Aleksandra, Jones, Michael, Ramus, Susan J, Orr, Nick, Menon, Usha, Pearce, Celeste L, Brüning, Thomas, Pike, Malcolm C, Ko, Yon-Dschun, Lissowska, Jolanta, Figueroa, Jonine, Kupryjanczyk, Jolanta, Chanock, Stephen J, Dansonka-Mieszkowska, Agnieszka, Jukkola-Vuorinen, Arja, Rzepecka, Iwona K, Pylkäs, Katri, Bidzinski, Mariusz, Kauppila, Saila, Hollestelle, Antoinette, Seynaeve, Caroline, Tollenaar, Rob A E M, Durda, Katarzyna, Jaworska, Katarzyna, Hartikainen, Jaana M, Kosma, Veli-Matti, Kataja, Vesa, Antonenkova, Natalia N, Long, Jirong, Shrubsole, Martha, Deming-Halverson, Sandra, Lophatananon, Artitaya, Siriwanarangsan, Pornthep, Stewart-Brown, Sarah, Ditsch, Nina, Lichtner, Peter, Schmutzler, Rita K, Ito, Hidemi, Iwata, Hiroji, Tajima, Kazuo, Tseng, Chiu-Chen, Stram, Daniel O, van den Berg, David, Yip, Cheng Har, Ikram, M Kamran, Teh, Yew-Ching, Cai, Hui, Lu, Wei, Signorello, Lisa B, Cai, Qiuyin, Noh, Dong-Young, Yoo, Keun-Young, Miao, Hui, Iau, Philip Tsau-Choong, Teo, Yik Ying, McKay, James, Shapiro, Charles, Ademuyiwa, Foluso, Fountzilas, George, Hsiung, Chia-Ni, Yu, Jyh-Cherng, Hou, Ming-Feng, Healey, Catherine S, Luccarini, Craig, Peock, Susan, Stoppa-Lyonnet, Dominique, Peterlongo, Paolo, Rebbeck, Timothy R, Piedmonte, Marion, Singer, Christian F, Friedman, Eitan, Thomassen, Mads, Offit, Kenneth, Hansen, Thomas V O, Neuhausen, Susan L, Szabo, Csilla I, Blanco, Ignacio, Garber, Judy, Narod, Steven A, Weitzel, Jeffrey N, Montagna, Marco, Olah, Edith, Godwin, Andrew K, Yannoukakos, Drakoulis, Goldgar, David E, Caldes, Trinidad, Imyanitov, Evgeny N, Tihomirova, Laima, Arun, Banu K, Campbell, Ian, Mensenkamp, Arjen R, van Asperen, Christi J, van Roozendaal, Kees E P, Meijers-Heijboer, Hanne, Collée, J Margriet, Oosterwijk, Jan C, Hooning, Maartje J, Rookus, Matti A, van der Luijt, Rob B, Os, Theo A Mvan, Evans, D Gareth, Frost, Debra, Fineberg, Elena, Barwell, Julian, Walker, Lisa, Kennedy, M John, Platte, Radka, Davidson, Rosemarie, Ellis, Steve D, Cole, Trevor, Bressac-de Paillerets, Brigitte, Buecher, Bruno, Damiola, Francesca, Faivre, Laurence, Frenay, Marc, Sinilnikova, Olga M, Caron, Olivier, Giraud, Sophie, Mazoyer, Sylvie, Bonadona, Valérie, Caux-Moncoutier, Virginie, Toloczko-Grabarek, Aleksandra, Gronwald, Jacek, Byrski, Tomasz, Spurdle, Amanda B, Bonanni, Bernardo, Zaffaroni, Daniela, Giannini, Giuseppe, Bernard, Loris, Dolcetti, Riccardo, Manoukian, Siranoush, Arnold, Norbert, Engel, Christoph, Deissler, Helmut, Rhiem, Kerstin, Niederacher, Dieter, Plendl, Hansjoerg, Sutter, Christian, Wappenschmidt, Barbara, Borg, Åke, Melin, Beatrice, Rantala, Johanna, Soller, Maria, Nathanson, Katherine L., Domchek, Susan M., Rodriguez, Gustavo C., Salani, Ritu, Kaulich, Daphne Gschwantler, Tea, Muy-Kheng, Paluch, Shani Shimon, Laitman, Yael, Skytte, Anne-Bine, Kruse, Torben A, Jensen, Uffe Birk, Robson, Mark, Gerdes, Anne-Marie, Ejlertsen, Bent, Foretova, Lenka, Savage, Sharon A., Lester, Jenny, Soucy, Penny, Kuchenbaecker, Karoline B., Olswold, Curtis, Cunningham, Julie M., Slager, Susan, Pankratz, Vernon S., Dicks, Ed, Lakhani, Sunil R., Couch, Fergus J., Hall, Per, Monteiro, Alvaro N.A., Gayther, Simon A., Pharoah, Paul D.P., Reddel, Roger R., Goode, Ellen L., Greene, Mark H., Easton, Douglas F., Berchuck, Andrew, Antoniou, Antonis C., Chenevix-Trench, Georgia and Dunning, Alison M.
    Published:
    2013
    Publication:
    Nature Genetics
    Volume:
    45, (4)
    Page Range:
    371-384
    doi:
    10.1038/ng.2566
    PMID:
    23535731
  • Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk - Hunter, Kent W., Gaudet, Mia M., Kuchenbaecker, Karoline B., Vijai, Joseph, Klein, Robert J., Kirchhoff, Tomas, McGuffog, Lesley, Barrowdale, Daniel, Dunning, Alison M., Lee, Andrew, Dennis, Joe, Healey, Sue, Dicks, Ed, Soucy, Penny, Sinilnikova, Olga M., Pankratz, Vernon S., Wang, Xianshu, Eldridge, Ronald C., Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Hogervorst, Frans B.L., Peock, Susan, Stoppa-Lyonnet, Dominique, Peterlongo, Paolo, Schmutzler, Rita K., Nathanson, Katherine L., Piedmonte, Marion, Singer, Christian F., Thomassen, Mads, Hansen, Thomas v. O., Neuhausen, Susan L., Blanco, Ignacio, Greene, Mark H., Garber, Judith, Weitzel, Jeffrey N., Andrulis, Irene L., Goldgar, David E., D'Andrea, Emma, Caldes, Trinidad, Nevanlinna, Heli, Osorio, Ana, van Rensburg, Elizabeth J., Arason, Adalgeir, Rennert, Gad, van den Ouweland, Ans M.W., van der Hout, Annemarie H., Kets, Carolien M., Aalfs, Cora M., Wijnen, Juul T., Ausems, Margreet G.E.M., Frost, Debra, Ellis, Steve, Fineberg, Elena, Platte, Radka, Evans, D. Gareth, Jacobs, Chris, Adlard, Julian, Tischkowitz, Marc, Porteous, Mary E., Damiola, Francesca, Golmard, Lisa, Barjhoux, Laure, Longy, Michel, Belotti, Muriel, Ferrer, Sandra Fert, Mazoyer, Sylvie, Spurdle, Amanda B., Manoukian, Siranoush, Barile, Monica, Genuardi, Maurizio, Arnold, Norbert, Meindl, Alfons, Sutter, Christian, Wappenschmidt, Barbara, Domchek, Susan M., Pfeiler, Georg, Friedman, Eitan, Jensen, Uffe Birk, Robson, Mark, Shah, Sohela, Lazaro, Conxi, Mai, Phuong L., Benitez, Javier, Southey, Melissa C., Schmidt, Marjanka K., Fasching, Peter A., Peto, Julian, Humphreys, Manjeet K., Wang, Qin, Michailidou, Kyriaki, Sawyer, Elinor J., Burwinkel, Barbara, Guénel, Pascal, Bojesen, Stig E., Milne, Roger L., Brenner, Hermann, Lochmann, Magdalena, Aittomäki, Kristiina, Dörk, Thilo, Margolin, Sara, Mannermaa, Arto, Lambrechts, Diether, Chang-Claude, Jenny, Radice, Paolo, Giles, Graham G., Haiman, Christopher A., Winqvist, Robert, Devillee, Peter, García-Closas, Montserrat, Schoof, Nils, Hooning, Maartje J., Cox, Angela, Pharoah, Paul D.P., Jakubowska, Anna, Orr, Nick, González-Neira, Anna, Pita, Guillermo, Alonso, M. Rosario, Hall, Per, Couch, Fergus J., Simard, Jacques, Altshuler, David, Easton, Douglas F., Chenevix-Trench, Georgia, Antoniou, Antonis C., Offit, Kenneth and Eccles, D.
    Published:
    2013
    Publication:
    PLoS Genetics
    Volume:
    9, (3)
    Page Range:
    e1003173-[15pp]
    doi:
    10.1371/journal.pgen.1003173
    PMID:
    23544012
  • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 - Permuth-Wey, Jennifer, Lawrenson, Kate, Shen, Howard C., Velkova, Aneliya, Tyrer, Jonathan P., Chen, Zhihua, Lin, Hui-Yi, Ann Chen, Y., Tsai, Ya-Yu, Qu, Xiaotao, Ramus, Susan J., Karevan, Rod, Lee, Janet, Lee, Nathan, Larson, Melissa C., Aben, Katja K., Anton-Culver, Hoda, Antonenkova, Natalia, Antoniou, Antonis C., Armasu, Sebastian M., Bacot, François, Baglietto, Laura, Bandera, Elisa V., Barnholtz-Sloan, Jill, Beckmann, Matthias W., Birrer, Michael J., Bloom, Greg, Bogdanova, Natalia, Brinton, Louise A., Brooks-Wilson, Angela, Brown, Robert, Butzow, Ralf, Cai, Qiuyin, Campbell, Ian, Chang-Claude, Jenny, Chanock, Stephen, Chenevix-Trench, Georgia, Cheng, Jin Q., Cicek, Mine S., Coetzee, Gerhard A., Cook, Linda S., Couch, Fergus J., Cramer, Daniel W., Cunningham, Julie M., Dansonka-Mieszkowska, Agnieszka, Despierre, Evelyn, Doherty, Jennifer A., Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Easton, Douglas F., Eccles, Diana, Edwards, Robert, Ekici, Arif B., Fasching, Peter A., Fenstermacher, David A., Flanagan, James M., Garcia-Closas, Montserrat, Gentry-Maharaj, Aleksandra, Giles, Graham G., Glasspool, Rosalind M., Gonzalez-Bosquet, Jesus, Goodman, Marc T., Gore, Martin, Górski, Bohdan, Gronwald, Jacek, Hall, Per, Halle, Mari K., Harter, Philipp, Heitz, Florian, Hillemanns, Peter, Hoatlin, Maureen, Høgdall, Claus K., Høgdall, Estrid, Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Jim, Heather, Kalli, Kimberly R., Karlan, Beth Y., Kaye, Stanley B., Kelemen, Linda E., Kiemeney, Lambertus A., Kikkawa, Fumitaka, Konecny, Gottfried E., Krakstad, Camilla, Krüger Kjaer, Susanne, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Lancaster, Johnathan M., Le, Nhu D., Leminen, Arto, Levine, Douglas A., Liang, Dong, Kiong Lim, Boon, Lin, Jie, Lissowska, Jolanta, Lu, Karen H., Lubiński, Jan, Lurie, Galina, Massuger, Leon F.A.G, Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R., Menon, Usha, Modugno, Francesmary, Moysich, Kirsten B., Nakanishi, Toru, Narod, Steven A., Nedergaard, Lotte, Ness, Roberta B., Nevanlinna, Heli, Nickels, Stefan, Noushmehr, Houtan, Odunsi, Kunle, Olson, Sara H., Orlow, Irene, Paul, James, Pearce, Celeste L., Pejovic, Tanja, Pelttari, Liisa M., Pike, Malcolm C., Poole, Elizabeth M., Raska, Paola, Renner, Stefan P., Risch, Harvey A., Rodriguez-Rodriguez, Lorna, Anne Rossing, Mary, Rudolph, Anja, Runnebaum, Ingo B., Rzepecka, Iwona K., Salvesen, Helga B., Schwaab, Ira, Severi, Gianluca, Shridhar, Viji, Shu, Xiao-Ou, Shvetsov, Yurii B., Sieh, Weiva, Song, Honglin, Southey, Melissa C., Spiewankiewicz, Beata, Stram, Daniel, Sutphen, Rebecca, Teo, Soo-Hwang, Terry, Kathryn L., Tessier, Daniel C., Thompson, Pamela J., Tworoger, Shelley S., van Altena, Anne M., Vergote, Ignace, Vierkant, Robert A., Vincent, Daniel, Vitonis, Allison F., Wang-Gohrke, Shan, Palmieri Weber, Rachel, Wentzensen, Nicolas, Whittemore, Alice S., Wik, Elisabeth, Wilkens, Lynne R., Winterhoff, Boris, Ling Woo, Yin, Wu, Anna H., Xiang, Yong-Bing, Yang, Hannah P., Zheng, Wei, Ziogas, Argyrios, Zulkifli, Famida, Phelan, Catherine M., Iversen, Edwin, Schildkraut, Joellen M., Berchuck, Andrew, Fridley, Brooke L., Goode, Ellen L., Pharoah, Paul D.P., Monteiro, Alvaro N.A., Sellers, Thomas A. and Gayther, Simon A.
    Published:
    2013
    Publication:
    Nature Communications
    Volume:
    4
    Page Range:
    1627
    doi:
    10.1038/ncomms2613
  • Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer - Shen, Hui, Fridley, Brooke L., Song, Honglin, Lawrenson, Kate, Cunningham, Julie M., Ramus, Susan J., Cicek, Mine S., Tyrer, Jonathan, Stram, Douglas, Larson, Melissa C., Köbel, Martin, Ziogas, Argyrios, Zheng, Wei, Yang, Hannah P., Wu, Anna H., Wozniak, Eva L., Ling Woo, Yin, Winterhoff, Boris, Wik, Elisabeth, Whittemore, Alice S., Wentzensen, Nicolas, Palmieri Weber, Rachel, Vitonis, Allison F., Vincent, Daniel, Vierkant, Robert A., Vergote, Ignace, Van Den Berg, David, Van Altena, Anne M., Tworoger, Shelley S., Thompson, Pamela J., Tessier, Daniel C., Terry, Kathryn L., Teo, Soo-Hwang, Templeman, Claire, Stram, Daniel O., Southey, Melissa C., Sieh, Weiva, Siddiqui, Nadeem, Shvetsov, Yurii B., Shu, Xiao-Ou, Shridhar, Viji, Wang-Gohrke, Shan, Severi, Gianluca, Schwaab, Ira, Salvesen, Helga B., Rzepecka, Iwona K., Runnebaum, Ingo B., Anne Rossing, Mary, Rodriguez-Rodriguez, Lorna, Risch, Harvey A., Renner, Stefan P., Poole, Elizabeth M., Pike, Malcolm C., Phelan, Catherine M., Pelttari, Liisa M., Pejovic, Tanja, Paul, James, Orlow, Irene, Zawiah Omar, Siti, Olson, Sara H., Odunsi, Kunle, Nickels, Stefan, Nevanlinna, Heli, Ness, Roberta B., Narod, Steven A., Nakanishi, Toru, Moysich, Kirsten B., Monteiro, Alvaro N.A., Moes-Sosnowska, Joanna, Modugno, Francesmary, Menon, Usha, McLaughlin, John R., McGuire, Valerie, Matsuo, Keitaro, Mat Adenan, Noor Azmi, Massuger, Leon F.A.G, Lurie, Galina, Lundvall, Lene, Lubiński, Jan, Lissowska, Jolanta, Levine, Douglas A., Leminen, Arto, Lee, Alice W., Le, Nhu D., Lambrechts, Sandrina, Lambrechts, Diether, Kupryjanczyk, Jolanta, Krakstad, Camilla, Konecny, Gottfried E., Krüger Kjaer, Susanne, Kiemeney, Lambertus A., Kelemen, Linda E., Keeney, Gary L., Karlan, Beth Y., Karevan, Rod, Kalli, Kimberly R., Kajiyama, Hiroaki, Ji, Bu-Tian, Jensen, Allan, Jakubowska, Anna, Iversen, Edwin, Hosono, Satoyo, Høgdall, Claus K., Høgdall, Estrid, Hoatlin, Maureen, Hillemanns, Peter, Heitz, Florian, Hein, Rebecca, Harter, Philipp, Halle, Mari K., Hall, Per, Gronwald, Jacek, Gore, Martin, Goodman, Marc T., Giles, Graham G., Gentry-Maharaj, Aleksandra, Garcia-Closas, Montserrat, Flanagan, James M., Fasching, Peter A., Ekici, Arif B., Edwards, Robert, Eccles, Diana, Easton, Douglas F., Dürst, Matthias, du Bois, Andreas, Dörk, Thilo, Doherty, Jennifer A., Despierre, Evelyn, Dansonka-Mieszkowska, Agnieszka, Cybulski, Cezary, Cramer, Daniel W., Cook, Linda S., Chen, Xiaoqing, Charbonneau, Bridget, Chang-Claude, Jenny, Campbell, Ian, Butzow, Ralf, Bunker, Clareann H., Brueggmann, Doerthe, Brown, Robert, Brooks-Wilson, Angela, Brinton, Louise A., Bogdanova, Natalia, Block, Matthew S., Benjamin, Elizabeth, Beesley, Jonathan, Beckmann, Matthias W., Bandera, Elisa V., Baglietto, Laura, Bacot, François, Armasu, Sebastian M., Antonenkova, Natalia, Anton-Culver, Hoda, Aben, Katja K., Liang, Dong, Wu, Xifeng, Lu, Karen, Hildebrandt, Michelle A.T., Schildkraut, Joellen M., Sellers, Thomas A., Huntsman, David, Berchuck, Andrew, Chenevix-Trench, Georgia, Gayther, Simon A., Pharoah, Paul D.P., Laird, Peter W., Goode, Ellen L. and Leigh Pearce, Celeste
    Published:
    2013
    Publication:
    Nature Communications
    Volume:
    4
    Page Range:
    1628-[10pp]
    doi:
    10.1038/ncomms2629
    PMID:
    23535649
  • Identification of inherited genetic variations influencing prognosis in early-onset breast cancer - Rafiq, Sajjad, Tapper, William, Collins, Andrew, Khan, Sofia, Politopoulos, Ionnis, Gerty, Sue, Blomqvist, Carl, Couch, Fergus J., Nevanlinna, Heli, Liu, Jianjun and Eccles, Diana
    Published:
    2013
    Publication:
    Cancer Research
    Volume:
    73, (6)
    Page Range:
    1883-1891
    doi:
    10.1158/0008-5472.CAN-12-3377
    PMID:
    23319801
  • Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas - Smith, Miriam J., O'Sullivan, James, Bhaskar, Sanjeev S., Hadfield, Kristen D., Poke, Gemma, Caird, John, Sharif, Saba, Eccles, Diana, Fitzpatrick, David, Rawluk, Daniel, du Plessis, Daniel, Newman, William G. and Evans, D. Gareth
    Published:
    2013
    Publication:
    Nature Genetics
    Volume:
    45, (3)
    Page Range:
    295-298
    doi:
    10.1038/ng.2552
    PMID:
    23377182
  • Stratified cancer screening: the practicalities of implementation - Dent, T., Jbilou, J., Rafi, I., Segnan, N., Törnberg, S., Chowdhury, S., Hall, A., Lyratzopoulos, G., Eeles, R., Eccles, D., Hallowell, N., Pashayan, N., Pharoah, P. and Burton, H.
    Published:
    2013
    Publication:
    Public Health Genomics
    doi:
    10.1159/000345941
    PMID:
    23363703
  • Analysis of RAD51D in ovarian cancer patients and families with a history of ovarian or breast cancer - Ellis, Nathan A., Thompson, Ella R., Rowley, Simone M., Sawyer, Sarah, kConFab, , Eccles, Diana M., Trainer, Alison H., Mitchell, Gillian, James, Paul A. and Campbell, Ian G.
    Published:
    2013
    Publication:
    PLoS ONE
    Volume:
    8, (1)
    Page Range:
    e54772
    doi:
    10.1371/journal.pone.0054772
  • Letter. Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer - Ruark, Elise, Snape, Katie, Humburg, Peter, Loveday, Chey, Bajrami, Ilirjana, Brough, Rachel, Rodrigues, Daniel Nava, Renwick, Anthony, Seal, Sheila, Ramsay, Emma, Duarte, Silvana Del Vecchio, Rivas, Manuel A., Warren-Perry, Margaret, Zachariou, Anna, Campion-Flora, Adriana, Hanks, Sandra, Murray, Anne, Pour, Naser Ansari, Douglas, Jenny, Gregory, Lorna, Rimmer, Andrew, Walker, Neil M., Yang, Tsun-Po, Adlard, Julian W., Barwell, Julian, Berg, Jonathan, Brady, Angela F., Brewer, Carole, Brice, Glen, Chapman, Cyril, Cook, Jackie, Davidson, Rosemarie, Donaldson, Alan, Douglas, Fiona, Eccles, Diana, Evans, D. Gareth, Greenhalgh, Lynn, Henderson, Alex, Izatt, Louise, Kumar, Ajith, Lalloo, Fiona, Miedzybrodzka, Zosia, Morrison, Patrick J., Paterson, Joan, Porteous, Mary, Rogers, Mark T., Shanley, Susan, Walker, Lisa, Gore, Martin, Houlston, Richard, Brown, Matthew A., Caufield, Mark J., Deloukas, Panagiotis, McCarthy, Mark I., Todd, John A., Turnbull, Clare, Reis-Filho, Jorge S., Ashworth, Alan, Antoniou, Antonis C., Lord, Christopher J., Donnelly, Peter and Rahman, Nazneen
    Published:
    2013
    Publication:
    Nature
    Volume:
    493, (7432)
    Page Range:
    406-410
    doi:
    10.1038/nature11725
    PMID:
    23242139
  • Results of annual screening in phase I of the United Kingdom familial ovarian cancer screening study highlight the need for strict adherence to screening schedule - Rosenthal, Adam N., Fraser, Lindsay, Manchanda, Ranjit, Badman, Philip, Philpott, Susan, Mozersky, Jessica, Hadwin, Richard, Cafferty, Fay H., Benjamin, Elizabeth, Singh, Naveena, Evans, D. Gareth, Eccles, Diana M., Skates, Steven J., Mackay, James, Menon, Usha and Jacobs, Ian J.
    Published:
    2013
    Publication:
    Journal of Clinical Oncology
    Volume:
    31, (1)
    Page Range:
    49-57
    doi:
    10.1200/JCO.2011.39.7638
    PMID:
    23213100
  • Therapeutic targeting of integrin ?v?6 in breast cancer. - Moore, K., Thomas, G., Duffy, S., Warwick, J., Gabe, R., Chou, P., Ellis, I., Green, A., Haider, S., Brouilette, K., Saha, A., Vallath, S., Bowen, R., Chelala, C., Eccles, D., Tapper, W., Thompson, A., Quinlan, P., Jordan, L., Gillett, C., Brentall, A., Violette, S., Weinreb, P., Kendrew, J., Barry , S., Hart, I., Jones, L. and Marshall, J.
    Published:
    2013
    Publication:
    Journal of the National Cancer Institute
  • A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11 - Siddiq, A., Couch, F.J., Chen, G.K., Lindstrom, S., Eccles, D., Millikan, R.C., Michailidou, K., Stram, D.O., Beckmann, L., Rhie, S.K., Ambrosone, C.B., Aittomaki, K., Amiano, P., Apicella, C., Baglietto, L., Bandera, E.V., Beckmann, M.W., Berg, C.D., Bernstein, L., Blomqvist, C., Brauch, H., Brinton, L., Bui, Q.M., Buring, J.E., Buys, S.S., Campa, D., Carpenter, J.E., Chasman, D.I., Chang-Claude, J., Chen, C., Clavel-Chapelon, F., Cox, A., Cross, S.S., Czene, K., Deming, S.L., Diasio, R.B., Diver, W.R., Dunning, A.M., Durcan, L., Ekici, A.B., Fasching, P.A., Feigelson, H.S., Fejerman, L., Figueroa, J.D., Fletcher, O., Flesch-Janys, D., Gaudet, M.M., Gerty, S.M., Rodriguez-Gil, J.L., Giles, G.G., van Gils, C.H., Godwin, A.K., Graham, N., Greco, D., Hall, P., Hankinson, S.E., Hartmann, A., Hein, R., Heinz, J., Hoover, R.N., Hopper, J.L., Hu, J.J., Huntsman, S., Ingles, S.A., Irwanto, A., Isaacs, C., Jacobs, K.B., John, E.M., Justenhoven, C., Kaaks, R., Kolonel, L.N., Coetzee, G.A., Lathrop, M., Le Marchand, L., Lee, A.M., Lee, I.-M., Lesnick, T., Lichtner, P., Liu, J., Lund, E., Makalic, E., Martin, N.G., McLean, C.A., Meijers-Heijboer, H., Meindl, A., Miron, P., Monroe, K.R., Montgomery, G.W., Muller-Myhsok, B., Nickels, S., Nyante, S.J., Olswold, C., Overvad, K., Palli, D., Park, D.J., Palmer, J.R., Pathak, H., Peto, J., Pharoah, P., Rahman, N., Rivadeneira, F., Schmidt, D.F., Schmutzler, R.K., Slager, S., Southey, M.C., Stevens, K.N., Sinn, H.-P., Press, M.F., Ross, E., Riboli, E., Ridker, P.M., Schumacher, F.R., Severi, G., dos Santos Silva, I., Stone, J., Sund, M., Tapper, W.J., Thun, M.J., Travis, R.C., Turnbull, C., Uitterlinden, A.G., Waisfisz, Q., Wang, X., Wang, Z., Weaver, J., Schulz-Wendtland, R., Wilkens, L.R., Van Den Berg, D., Zheng, W., Ziegler, R.G., Ziv, E., Nevanlinna, H., Easton, D.F., Hunter, D.J., Henderson, B.E., Chanock, S.J., Garcia-Closas, M., Kraft, P., Haiman, C.A. and Vachon, C.M.
    Published:
    2012
    Publication:
    Human Molecular Genetics
    Volume:
    21, (24)
    Page Range:
    5373-5384
    doi:
    10.1093/hmg/dds381
    PMID:
    22976474
  • Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial - Mathers, John C., Movahedi, Mohammad, Macrae, Finlay, Mecklin, Jukka-Pekka, Moeslein, Gabriela, Olschwang, Sylviane, Eccles, Diana, Evans, Gareth, Maher, Eamonn R, Bertario, Lucio, Bisgaard, Marie-Luise, Dunlop, Malcolm, Ho, Judy W.C., Hodgson, Shirley, Lindblom, Annika, Lubinski, Jan, Morrison, Patrick J., Murday, Victoria, Ramesar, Raj, Side, Lucy, Scott, Rodney J., Thomas, Huw J.W., Vasen, Hans, Gerdes, Anne-Marie, Barker, Gail, Crawford, Gillian, Elliott, Faye, Pylvanainen, Kirsi, Wijnen, Juul, Fodde, Riccardo, Lynch, Henry, Bishop, D. Timothy and Burn, John
    Published:
    2012
    Publication:
    The Lancet Oncology
    Volume:
    13, (12)
    Page Range:
    1242-1249
    doi:
    10.1016/S1470-2045(12)70475-8
    PMID:
    23140761
  • A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers - Ding, Yuan C., McGuffog, Lesley, Healey, Sue, Friedman, Eitan, Laitman, Yael, Paluch-Shimon, Shani, Kaufman, Bella, Liljegren, Annelie, Lindblom, Annika, Olsson, Håkan, Kristoffersson, Ulf, Stenmark-Askmalm, Marie, Melin, Beatrice, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Jakubowska, Anna, Lubinski, Jan, Jaworska, Katarzyna, Durda, Katarzyna, Gronwald, Jacek, Huzarski, Tomasz, Cybulski, Cezary, Byrski, Tomasz, Osorio, Ana, Cajal, Teresa Ramóny, Stavropoulou, Alexandra V., Benitez, Javier, Hamann, Ute, Rookus, Matti, Aalfs, Cora M., de Lange, Judith L., Meijers-Heijboer, Hanne E.J., Oosterwijk, Jan C., van Asperen, Christi J., Gomez Garcia, Encarna B., Hoogerbrugge, Nicoline, Jager, Agnes, van der Luijt, Rob B., Easton, Douglas F., Peock, Susan, Frost, Debra, Ellis, Steve D., Platte, Radka, Fineberg, Elena, Evans, D. Gareth, Lalloo, Fiona, Izatt, Louise, Eeles, Ros, Adlard, Julian, Davidson, Rosemarie, Eccles, Diana, Cole, Trevor, Cook, Jackie, Brewer, Carole, Tischkowitz, Marc, Godwin, Andrew K., Pathak, Harsh, Stoppa-Lyonnet, Dominique, Sinilnikova, Olga M., Mazoyer, Sylvie, Barjhoux, Laure, Léoné, Mélanie, Gauthier-Villars, Marion, Caux-Moncoutier, Virginie, de Pauw, Antoine, Hardouin, Agnès, Berthet, Pascaline, Dreyfus, Hélène, Ferrer, Sandra Fert, Collonge-Rame, Marie-Agnès, Sokolowska, Johanna, Buys, Sandra, Daly, Mary, Miron, Alex, Terry, M.B., Chung, W., John, E.M., Southey, M., Goldgar, D., Singer, C.F., Tea, M.-K.M., Gschwantler-Kaulich, D., Fink-Retter, A., Hansen, T.V.O., Ejlertsen, B., Johannsson, O.T., Offit, K., Sarrel, K., Gaudet, M.M., Vijai, J., Robson, M., Piedmonte, M.R., Andrews, L., Cohn, D., DeMars, L.R., DiSilvestro, P., Rodriguez, G., Toland, A.E., Montagna, M., Agata, S., Imyanitov, E., Isaacs, C., Janavicius, R., Lazaro, C., Blanco, I., Ramus, S.J., Sucheston, L., Karlan, B.Y., Gross, J., Ganz, P.A., Beattie, M.S., Schmutzler, R.K., Wappenschmidt, B., Meindl, A., Arnold, N., Niederacher, D., Preisler-Adams, S., Gadzicki, D., Varon-Mateeva, R., Deissler, H., Gehrig, A., Sutter, C., Kast, K., Nevanlinna, H., Aittomaki, K., Simard, J., Spurdle, A.B., Beesley, J., Chen, X., Tomlinson, G.E., Weitzel, J., Garber, J.E., Olopade, O.I., Rubinstein, W.S., Tung, N., Blum, J.L., Narod, S.A., Brummel, S., Gillen, D.L., Lindor, N., Fredericksen, Z., Pankratz, V.S., Couch, F.J., Radice, P., Peterlongo, P., Greene, M.H., Loud, J.T., Mai, P.L., Andrulis, I.L., Glendon, G., Ozcelik, H., Gerdes, A.-M., Thomassen, M., Jensen, U.B., Skytte, A.-B., Caligo, M.A., Lee, A., Chenevix-Trench, G., Antoniou, A.C. and Neuhausen, S.L.
    Published:
    2012
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    21, (8)
    Page Range:
    1362-1370
    doi:
    10.1158/1055-9965.EPI-12-0229
    PMID:
    22729394
  • BRCA1 R1699Q variant displaying ambiguous functional abrogation confers intermediate breast and ovarian cancer risk - Spurdle, A.B., Whiley, P.J., Thompson, B., Feng, B., Healey, S., Brown, M.A., Pettigrew, C., Van Asperen, C.J., Ausems, M.G.E.M., Kattentidt-Mouravieva, A.A., van den Ouweland, A.M.W., Belgium UV Consortium, D., Lindblom, A., Pigg, M.H., Schmutzler, R.K., Engel, C., Meindl, A., Caputo, S., Sinilnikova, O.M., Lidereau, R., Couch, F.J., Guidugli, L., Hansen, T.v.O., Thomassen, M., Eccles, D.M., Tucker, K., Benitez, J., Domchek, S.M., Toland, A.E., Van Rensburg, E.J., Wappenschmidt, B., Borg, A., Vreeswijk, M.P.G. and Goldgar, D.E.
    Published:
    2012
    Publication:
    Journal of Medical Genetics
    Volume:
    49, (8)
    Page Range:
    525-532
    doi:
    10.1136/jmedgenet-2012-101037
    PMID:
    22889855
  • Analysis of KLLN as a high-penetrance breast cancer predisposition gene - Thompson, Ella R., Gorringe, Kylie L., Choong, David Y.H., Eccles, Diana M., Mitchell, Gillian and Campbell, Ian G.
    Published:
    2012
    Publication:
    Breast Cancer Research and Treatment
    Volume:
    134, (2)
    Page Range:
    543-547
    doi:
    10.1007/s10549-012-2088-3
  • Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study - Jakubowska, A., Rozkrut, D., Antoniou, A., Hamann, U., Scott, R.J., McGuffog, L., Healy, S., Sinilnikova, O.M., Rennert, G., Lejbkowicz, F., Flugelman, A., Andrulis, I.L., Glendon, G., Ozcelik, H., Thomassen, M., Paligo, M., Aretini, P., Kantala, J., Aroer, B., von Wachenfeldt, A., Liljegren, A., Loman, N., Herbst, K., Kristoffersson, U., Rosenquist, R., Karlsson, P., Stenmark-Askmalm, M., Melin, B., Nathanson, K.L., Domchek, S.M., Byrski, T., Huzarski, T., Gronwald, J., Menkiszak, J., Cybulski, C., Serrano, P., Osorio, A., Cajal, T.R., Tsitlaidou, M., Benítez, J., Gilbert, M., Rookus, M., Aalfs, C.M., Kluijt, I., Boessenkool-Pape, J.L., Meijers-Heijboer, H.E.J., Oosterwijk, J.C., van Asperen, C.J., Blok, M.J., Nelen, M.R., van den Ouweland, A.M.W., Seynaeve, C., van der Luijt, R.B., Devilee, P., Easton, D.F., Peock, S., Frost, D., Platte, R., Ellis, S.D., Fineberg, E., Evans, D.G., Lalloo, F., Eeles, R., Jacobs, C., Adlard, J., Davidson, R., Eccles, D., Cole, T., Cook, J., Godwin, A., Bove, B., Stoppa-Lyonnet, D., Caux-Moncoutier, V., Belotti, M., Tirapo, C., Mazoyer, S., Barjhoux, L., Boutry-Kryza, N., Pujol, P., Coupier, I., Peyrat, J.-P., Vennin, P., Muller, D., Fricker, J.-P., Venat-Bouvet, L., Johannsson, O.Th., Isaacs, C., Schmutzler, R., Wappenschmidt, B., Meindl, A., Arnold, N., Varon-Mateeva, R., Niederacher, D., Sutter, C., Deissler, H., Preisler-Adams, S., Simard, J., Soucy, P., Durocher, F., Chenevix-Trench, G., Beesley, J., Chen, X., Rebbeck, T., Couch, F., Wang, X., Lindor, N., Fredericksen, Z., Pankratz, V.S., Peterlongo, P., Bonanni, B., Fortuzzi, S., Peissel, B., Szabo, C., Mai, P.L., Loud, J.T. and Lubinski, J.
    Published:
    2012
    Publication:
    British Journal of Cancer
    Volume:
    106, (12)
    Page Range:
    2016-2024
    doi:
    10.1038/bjc.2012.160
    PMID:
    22669161
  • Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study - Shaw, Emily C., Hanby, Andrew M., Wheeler, Kevin, Shaaban, Abeer M., Poller, David, Barton, Sheila, Treanor, Darren, Fulford, Laura, Walker, Rosemary A., Ryan, Deirdre, Lakhani, Sunil R., Wells, Clive A., Roche, Heather, Theaker, Jeffrey M., Ellis, Ian O., Jones, J. Louise and Eccles, D. M.
    Published:
    2012
    Publication:
    Journal of Clinical Pathology
    Volume:
    65, (5)
    Page Range:
    403-408
    doi:
    10.1136/jclinpath-2011-200369
    PMID:
    22447915
  • Germline RAD51C mutations confer susceptibility to ovarian cancer - Loveday, Chey, Turnbull, Clare, Ruark, Elise, Xicola, Rosa Maria Munoz, Ramsay, Emma, Hughes, Deborah, Warren-Perry, Margaret, Snape, Katie, Eccles, Diana, Evans, D Gareth, Gore, Martin, Renwick, Anthony, Seal, Sheila, Antoniou, Antonis C. and Rahman, Nazneen
    Published:
    2012
    Publication:
    Nature Genetics
    Volume:
    44, (5)
    Page Range:
    475-476
    doi:
    10.1038/ng.2224
    PMID:
    22538716
  • Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers - Maia, Ana-Teresa, Antoniou, Antonis C, O'Reilly, Martin, Samarajiwa, Shamith, Dunning, Mark, Kartsonaki, Christiana, Chin, Suet-Feung, Curtis, Christina N., McGuffog, Lesley, Domchek, Susan M., Easton, Douglas F., Peock, Susan, Frost, Debra, Evans, D.G., Eeles, Ros, Izatt, Louise, Adlard, Julian, Eccles, Diana, Sinilnikova, Olga M., Mazoyer, Sylvie, Stoppa-Lyonnet, Dominique, Gauthier-Villars, Marion, Faivre, Laurence, Venat-Bouvet, Laurence, Delnatte, Capucine, Nevanlinna, Heli, Couch, Fergus J., Godwin, Andrew K., Caligo, Maria A., Barkardottir, Rosa B., Chen, Xiaoqing, Beesley, Jonathan, Healey, Sue, Caldas, Carlos, Chenevix-Trench, Georgia and Ponder, Bruce A.J.
    Published:
    2012
    Publication:
    Breast Cancer Research
    Volume:
    14, (2)
    Page Range:
    R63
    doi:
    10.1186/bcr3169
    PMID:
    22513257
  • 19p13.1 is a triple-negative-specific breast cancer susceptibility locus - Stevens, K.N., Fredericksen, Z., Vachon, C.M., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomaki, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H.-P., Wang-Gohrke, S., Nickels, S., Brauch, H., Ko, Y.-D., Fischer, H.-P., Schmutzler, R.K., Meindl, A., Bartram, C.R., Schott, S., Engel, C., Godwin, A.K., Weaver, J., Pathak, H.B., Sharma, P., Brenner, H., Muller, H., Arndt, V., Stegmaier, C., Miron, P., Yannoukakos, D., Stavropoulou, A., Fountzilas, G., Gogas, H. J., Swann, R., Dwek, M., Perkins, A., Milne, R. L., Benitez, J., Zamora, M. P., Perez, J. I. A., Bojesen, S. E., Nielsen, S. F., Nordestgaard, B. G., Flyger, H., Guenel, P., Truong, T., Menegaux, F., Cordina-Duverger, E., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Sawyer, E., Tomlinson, I., Kerin, M. J., Peto, J., Johnson, N., Fletcher, O., dos Santos Silva, I., Fasching, P. A., Beckmann, M. W., Hartmann, A., Ekici, A. B., Lophatananon, A., Muir, K., Puttawibul, P., Wiangnon, S., Schmidt, M. K., Broeks, A., Braaf, L. M., Rosenberg, E. H., Hopper, J. L., Apicella, C., Park, D. J., Southey, M. C., Swerdlow, A. J., Ashworth, A., Orr, N., Schoemaker, M. J., Anton-Culver, H., Ziogas, A., Bernstein, L., Dur, C. C., Shen, C.-Y., Yu, J.-C., Hsu, H.-M., Hsiung, C.-N., Hamann, U., Dunnebier, T., Rudiger, T., Ulmer, H. U., Pharoah, P. P., Dunning, A. M., Humphreys, M. K., Wang, Q., Cox, A., Cross, S. S., Reed, M. W., Hall, P., Czene, K., Ambrosone, C. B., Ademuyiwa, F., Hwang, H., Eccles, D. M., Garcia-Closas, M., Figueroa, J. D., Sherman, M. E., Lissowska, J., Devilee, P., Seynaeve, C., Tollenaar, R. A. E. M., Hooning, M. J., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., John, E. M., Miron, A., Alnaes, G. G., Kristensen, V., Borresen-Dale, A.-L., Giles, G. G., Baglietto, L., McLean, C. A., Severi, G., Kosel, M. L., Pankratz, V. S., Slager, S., Olson, J. E., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Lambrechts, D., Hatse, S., Dieudonne, A.-S., Christiaens, M.-R., Chenevix-Trench, G., Beesley, J., Chen, X., Mannermaa, A., Kosma, V.-M., Hartikainen, J. M., Soini, Y., Easton, D. F. and Couch, F. J.
    Published:
    2012
    Publication:
    Cancer Research
    Volume:
    72, (7)
    Page Range:
    1795-1803
    doi:
    10.1158/0008-5472.CAN-11-3364
    PMID:
    22331459
  • Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers - Ramus, Susan J., Antoniou, Antonis C., Kuchenbaecker, Karoline B., Soucy, Penny, Beesley, Jonathan, Chen, Xiaoqing, McGuffog, Lesley, Sinilnikova, Olga M., Healey, Sue, Barrowdale, Daniel, Lee, Andrew, Thomassen, Mads, Gerdes, Anne-Marie, Kruse, Torben A., Jensen, Uffe Birk, Skytte, Anne-Bine, Caligo, Maria A., Liljegren, Annelie, Lindblom, Annika, Olsson, Håkan, Kristoffersson, Ulf, Stenmark-Askmalm, Marie, Melin, Beatrice, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Jakubowska, Anna, Lubinski, Jan, Jaworska, Katarzyna, Durda, Katarzyna, Złowocka, Elżbieta, Gronwald, Jacek, Huzarski, Tomasz, Byrski, Tomasz, Cybulski, Cezary, Toloczko-Grabarek, Aleksandra, Osorio, Ana, Benitez, Javier, Duran, Mercedes, Tejada, Maria-Isabel, Hamann, Ute, Rookus, Matti, van Leeuwen, Flora E., Aalfs, Cora M., Meijers-Heijboer, Hanne E.J., van Asperen, Christi J., van Roozendaal, K.E.P., Hoogerbrugge, Nicoline, Collée, J. Margriet, Kriege, Mieke, van der Luijt, Rob B., Peock, Susan, Frost, Debra, Ellis, Steve D., Platte, Radka, Fineberg, Elena, Evans, D. Gareth, Lalloo, Fiona, Jacobs, Chris, Eeles, Ros, Adlard, Julian, Davidson, Rosemarie, Eccles, Diana, Cole, Trevor, Cook, Jackie, Paterson, Joan, Douglas, Fiona, Brewer, Carole, Hodgson, Shirley, Morrison, Patrick J., Walker, Lisa, Porteous, Mary E., Kennedy, M. John, Pathak, Harsh, Godwin, Andrew K., Stoppa-Lyonnet, Dominique, Caux-Moncoutier, Virginie, de Pauw, Antoine, Gauthier-Villars, Marion, Mazoyer, Sylvie, Léoné, Mélanie, Calender, Alain, Lasset, Christine, Bonadona, Valérie, Hardouin, Agnès, Berthet, Pascaline, Bignon, Yves-Jean, Uhrhammer, Nancy, Faivre, Laurence, Loustalot, Catherine, Buys, Saundra, Daly, Mary, Miron, Alex, Beth Terry, Mary, Chung, Wendy K., John, Esther M, Southey, Melissa, Goldgar, David, Singer, Christian F., Tea, Muy-Kheng, Pfeiler, Georg, Fink-Retter, Anneliese, Hansen, Thomas v. O., Ejlertsen, Bent, Johannsson, Oskar Th., Offit, Kenneth, Kirchhoff, Tomas, Gaudet, Mia M., Vijai, Joseph, Robson, Mark, Piedmonte, Marion, Phillips, Kelly-Anne, Van Le, Linda, Hoffman, James S, Toland, Amanda Ewart, Montagna, Marco, Tognazzo, Silvia, Imyanitov, Evgeny, Isaacs, Claudine, Janavicius, Ramunas, Lazaro, Conxi, Blanco, Ignacio, Tornero, Eva, Navarro, Matilde, Moysich, Kirsten B., Karlan, Beth Y., Gross, Jenny, Olah, Edith, Vaszko, Tibor, Teo, Soo-Hwang, Ganz, Patricia A., Beattie, Mary S., Dorfling, Cecelia M, van Rensburg, Elizabeth J., Diez, Orland, Kwong, Ava, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph, Meindl, Alfons, Ditsch, Nina, Arnold, Norbert, Heidemann, Simone, Niederacher, Dieter, Preisler-Adams, Sabine, Gadzicki, Dorotehea, Varon-Mateeva, Raymonda, Deissler, Helmut, Gehrig, Andrea, Sutter, Christian, Kast, Karin, Fiebig, Britta, Schäfer, Dieter, Caldes, Trinidad, de la Hoya, Miguel, Nevanlinna, Heli, Aittomäki, Kristiina, Plante, Marie, Spurdle, Amanda B., Neuhausen, Susan L., Ding, Yuan Chun, Wang, Xianshu, Lindor, Noralane, Fredericksen, Zachary, Pankratz, V. Shane, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Bonanni, Bernardo, Bernard, Loris, Dolcetti, Riccardo, Papi, Laura, Ottini, Laura, Radice, Paolo, Greene, Mark H., Mai, Phuong L., Andrulis, Irene L., Glendon, Gord, Ozcelik, Hilmi, Pharoah, Paul D.P., Gayther, Simon A., Simard, Jacques, Easton, Douglas F., Couch, Fergus J. and Chenevix-Trench, Georgia
    Published:
    2012
    Publication:
    Human Mutation
    Volume:
    33, (4)
    Page Range:
    690-702
    doi:
    10.1002/humu.22025
    PMID:
    22253144
  • Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers - Couch, Fergus J., Gaudet, Mia M., Antoniou, Antonis C., Ramus, Susan J., Kuchenbaecker, Karoline B., Soucy, Penny, Beesley, Jonathan, Chen, Xiaoqing, Wang, Xianshu, Kirchhoff, Tomas, McGuffog, Lesley, Barrowdale, Daniel, Lee, Andrew, Healey, Sue, Sinilnikova, Olga M., Andrulis, Irene L., Ozcelik, Hilmi, Mulligan, Anna Marie, Thomassen, Mads, Gerdes, Anne-Marie, Jensen, Uffe Birk, Skytte, Anne-Bine, Kruse, Torben A., Caligo, Maria A., von Wachenfeldt, Anna, Barbany-Bustinza, Gisela, Loman, Niklas, Soller, Maria, Ehrencrona, Hans, Karlsson, Per, Nathanson, Katherine L., Rebbeck, Timothy R., Domchek, Susan M., Jakubowska, Ania, Lubinski, Jan, Jaworska, Katarzyna, Durda, Katarzyna, Zlowocka, Elżbieta, Huzarski, Tomasz, Byrski, Tomasz, Gronwald, Jacek, Cybulski, Cezary, Gorski, Bohdan, Osorio, Ana, Duran, Mercedes, Tejada, María Isabel, Benitez, Javier, Hamann, Ute, Hogervorst, Frans B.L., van Os, Theo A., van Leeuwen, Flora E., Meijers-Heijboer, Hanne E.J., Wijnen, Juul, Blok, Marinus J., Kets, Marleen, Hooning, Maartje J., Oldenburg, Rogier A., Ausems, Margreet G.E.M., Peock, Susan, Frost, Debra, Ellis, Steve D., Platte, Radka, Fineberg, Elena, Evans, D. Gareth, Jacobs, Chris, Eeles, Rosalind A., Adlard, Julian, Davidson, Rosemarie, Eccles, Diana M., Cole, Trevor, Cook, Jackie, Paterson, Joan, Brewer, Carole, Douglas, Fiona, Hodgson, Shirley V., Morrison, Patrick J., Walker, Lisa, Porteous, Mary E., Kennedy, M. John, Side, Lucy E., Bove, Betsy, Godwin, Andrew K., Stoppa-Lyonnet, Dominique, Fassy-Colcombet, Marion, Castera, Laurent, Cornelis, François, Mazoyer, Sylvie, Leone, Mélanie, Boutry-Kryza, Nadia, Bressac-de Paillerets, Brigitte, Caron, Olivier, Pujol, Pascal, Coupier, Isabelle, Delnatte, Capuchine, Akloul, Linda, Lynch, Henry T., Snyder, Carrie L., Buys, Saundra S., Daly, Mary B., Terry, MaryBeth, Chung, Wendy K., John, Esther M., Miron, Alexander, Southey, Melissa C., Hopper, John L., Goldgar, David E., Singer, Christian F., Rappaport, Christine, Tea, Muy-Kheng M., Fink-Retter, Anneliese, Hansen, Thomas V.O., Nielsen, Finn C., Arason, Aðalgeir, Vijai, Joseph, Shah, Sohela, Sarrel, Kara, Robson, Mark E., Piedmonte, Marion, Phillips, Kelly, Basil, Jack, Rubinstein, Wendy S., Boggess, John, Wakeley, Katie, Ewart-Toland, Amanda, Montagna, Marco, Agata, Simona, Imyanitov, Evgeny N., Isaacs, Claudine, Janavicius, Ramunas, Lazaro, Conxi, Blanco, Ignacio, Feliubadalo, Lidia, Brunet, Joan, Gayther, Simon A., Pharoah, Paul P.D., Odunsi, Kunle O., Karlan, Beth Y., Walsh, Christine S., Olah, Edith, Teo, Soo Hwang, Ganz, Patricia A., Beattie, Mary S., van Rensburg, Elizabeth J., Dorfling, Cecelia M., Diez, Orland, Kwong, Ava, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph, Meindl, Alfons, Ditsch, Nina, Arnold, Norbert, Heidemann, Simone, Niederacher, Dieter, Preisler-Adams, Sabine, Gadzicki, Dorothea, Varon-Mateeva, Raymonda, Deissler, Helmut, Gehrig, Andrea, Sutter, Christian, Kast, Karin, Fiebig, Britta, Heinritz, Wolfram, Caldes, Trinidad, de la Hoya, Miguel, Muranen, Tara A., Nevanlinna, Heli, Tischkowitz, Marc D., Spurdle, Amanda B., Neuhausen, Susan L., Ding, Yuan Chun, Lindor, Noralane M., Fredericksen, Zachary, Pankratz, V. Shane, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Barile, Monica, Bernard, Loris, Viel, Alessandra, Giannini, Giuseppe, Varesco, Liliana, Radice, Paolo, Greene, Mark H., Mai, Phuong L., Easton, Douglas F., Chenevix-Trench, Georgia, Offit, Kenneth and Simard, Jacques
    Published:
    2012
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    21, (4)
    Page Range:
    645-657
    doi:
    10.1158/1055-9965.EPI-11-0888
    PMID:
    22351618
  • BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years - Robertson, L., Hanson, H., Seal, S., Warren-Perry, M., Hughes, D., Howell, I., Turnbull, C., Houlston, R., Shanley, S., Butler, S., Evans, D.G., Ross, G., Eccles, D., Tutt, A. and Rahman, N.
    Published:
    2012
    Publication:
    British Journal of Cancer
    Volume:
    106, (6)
    Page Range:
    1234-1238
    doi:
    10.1038/bjc.2012.31
    PMID:
    22333603
  • Gene-gene interactions in breast cancer susceptibility - Turnbull, C., Seal, S., Renwick, A., Warren-Perry, M., Hughes, D., Elliott, A., Pernet, D., Peock, S., Adlard, J.W., Barwell, J., Berg, J., Brady, A.F., Brewer, C., Brice, G., Chapman, C., Cook, J., Davidson, R., Donaldson, A., Douglas, F., Greenhalgh, L., Henderson, A., Izatt, L., Kumar, A., Lalloo, F., Miedzybrodzka, Z., Morrison, P.J., Paterson, J., Porteous, M., Rogers, M.T., Shanley, S., Walker, L., Ahmed, M., Eccles, D., Evans, D.G., Donnelly, P., Easton, D.F., Stratton, M.R. and Rahman, N.
    Published:
    2012
    Publication:
    Human Molecular Genetics
    Volume:
    21, (4)
    Page Range:
    958-962
    doi:
    10.1093/hmg/ddr525
    PMID:
    22072393
  • Genome-wide association analysis identifies three new breast cancer susceptibility loci - Ghoussaini, Maya, Fletcher, Olivia, Michailidou, Kyriaki, Turnbull, Clare, Schmidt, Marjanka K., Dicks, Ed, Dennis, Joe, Wang, Qin, Humphreys, Manjeet K., Luccarini, Craig, Baynes, Caroline, Conroy, Don, Maranian, Melanie, Ahmed, Shahana, Driver, Kristy, Johnson, Nichola, Orr, Nicholas, dos Santos Silva, Isabel, Waisfisz, Quinten, Meijers-Heijboer, Hanne, Uitterlinden, Andre G., Rivadeneira, Fernando, Hall, Per, Czene, Kamila, Irwanto, Astrid, Liu, Jianjun, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Meindl, Alfons, Schmutzler, Rita K., Müller-Myhsok, Bertram, Lichtner, Peter, Chang-Claude, Jenny, Hein, Rebecca, Nickels, Stefan, Flesch-Janys, Dieter, Tsimiklis, Helen, Makalic, Enes, Schmidt, Daniel, Bui, Minh, Hopper, John L., Apicella, Carmel, Park, Daniel J., Southey, Melissa, Hunter, David J., Chanock, Stephen J., Broeks, Annegien, Verhoef, Senno, Hogervorst, Frans B.L., Fasching, Peter A., Lux, Michael P., Beckmann, Matthias W., Ekici, Arif B., Sawyer, Elinor, Tomlinson, Ian, Kerin, Michael, Marme, Frederik, Schneeweiss, Andreas, Sohn, Christof, Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Cordina-Duverger, Emilie, Menegaux, Florence, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Milne, Roger L., Alonso, M. Rosario, González-Neira, Anna, Benítez, Javier, Anton-Culver, Hoda, Ziogas, Argyrios, Bernstein, Leslie, Dur, Christina Clarke, Brenner, Hermann, Müller, Heiko, Arndt, Volker, Stegmaier, Christa, Justenhoven, Christina, Brauch, Hiltrud, Brüning, Thomas, Wang-Gohrke, Shan, Eilber, Ursula, Dörk, Thilo, Schürmann, Peter, Bremer, Michael, Hillemanns, Peter, Bogdanova, Natalia V., Antonenkova, Natalia N., Rogov, Yuri I., Karstens, Johann H., Bermisheva, Marina, Prokofieva, Darya, Khusnutdinova, Elza, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Lambrechts, Diether, Yesilyurt, Betul T., Floris, Giuseppe, Leunen, Karin, Manoukian, Siranoush, Bonanni, Bernardo, Fortuzzi, Stefano, Peterlongo, Paolo, Couch, Fergus J., Wang, Xianshu, Stevens, Kristen, Lee, Adam, Giles, Graham G., Baglietto, Laura, Severi, Gianluca, McLean, Catriona, Alnæs, Grethe Grenaker, Kristensen, Vessela, Børrensen-Dale, Anne-Lise, John, Esther M., Miron, Alexander, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Kauppila, Saila, Andrulis, Irene L., Glendon, Gord, Mulligan, Anna Marie, Devilee, Peter, van Asperen, Christie J., Tollenaar, Rob A.E.M., Seynaeve, Caroline, Figueroa, Jonine D., Garcia-Closas, Montserrat, Brinton, Louise, Lissowska, Jolanta, Hooning, Maartje J., Hollestelle, Antoinette, Oldenburg, Rogier A., van den Ouweland, Ans M.W., Cox, Angela, Reed, Malcolm W.R., Shah, Mitul, Jakubowska, Ania, Lubinski, Jan, Jaworska, Katarzyna, Durda, Katarzyna, Jones, Michael, Schoemaker, Minouk, Ashworth, Alan, Swerdlow, Anthony, Beesley, Jonathan, Chen, Xiaoqing, Muir, Kenneth R., Lophatananon, Artitaya, Rattanamongkongul, Suthee, Chaiwerawattana, Arkom, Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Shen, Chen-Yang, Yu, Jyh-Cherng, Wu, Pei-Ei, Hsiung, Chia-Ni, Perkins, Annie, Swann, Ruth, Velentzis, Louiza, Eccles, Diana M., Tapper, Will J., Gerty, Susan M., Graham, Nikki J., Ponder, Bruce A.J., Chenevix-Trench, Georgia, Pharoah, Paul D.P., Lathrop, Mark, Dunning, Alison M., Rahman, Nazneen, Peto, Julian and Easton, Douglas F.
    Published:
    2012
    Publication:
    Nature Genetics
    Volume:
    44, (3)
    Page Range:
    312-318
    doi:
    10.1038/ng.1049
    PMID:
    22267197
  • Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the consortium of investigators of modifiers of BRCA1/2 (CIMBA) - Mavaddat, N., Barrowdale, D., Andrulis, I.L., Domchek, S.M., Eccles, D., Nevanlinna, H., Ramus, S.J., Spurdle, A., Robson, M., Sherman, M., Mulligan, A.M., Couch, F.J., Engel, C., McGuffog, L., Healey, S., Sinilnikova, O.M., Southey, M.C., Terry, M.B., Goldgar, D., O'Malley, F., John, E. M., Janavicius, R., Tihomirova, L., Hansen, T.V.O., Nielsen, F.C., Osorio, A., Stavropoulou, A., Benitez, J., Manoukian, S., Peissel, B., Barile, M., Volorio, S., Pasini, B., Dolcetti, R., Putignano, A.L., Ottini, L., Radice, P., Hamann, U., Rashid, M.U., Hogervorst, F.B., Kriege, M., van der Luijt, R.B., Peock, S., Frost, D., Evans, D.G., Brewer, C., Walker, L., Rogers, M.T., Side, L.E., Houghton, C., Weaver, J., Godwin, A.K., Schmutzler, R.K., Wappenschmidt, B., Meindl, A., Kast, K., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Preisler-Adams, S., Varon-Mateeva, R., Schonbuchner, I., Gevensleben, H., Stoppa-Lyonnet, D., Belotti, M., Barjhoux, L., Isaacs, C., Peshkin, B.N., Caldes, T., de la Hoya, M., Canadas, C., Heikkinen, T., Heikkila, P., Aittomaki, K., Blanco, I., Lazaro, C., Brunet, J., Agnarsson, B.A., Arason, A., Barkardottir, R.B., Dumont, M., Simard, J., Montagna, M., Agata, S., D'Andrea, E., Yan, M., Fox, S., Rebbeck, T.R., Rubinstein, W., Tung, N., Garber, J.E., Wang, X., Fredericksen, Z., Pankratz, V.S., Lindor, N.M., Szabo, C., Offit, K., Sakr, R., Gaudet, M.M., Singer, C.F., Tea, M.-K., Rappaport, C., Mai, P. L., Greene, M.H., Sokolenko, A., Imyanitov, E., Toland, A.E., Senter, L., Sweet, K., Thomassen, M., Gerdes, A.-M., Kruse, T., Caligo, M., Aretini, P., Rantala, J., von Wachenfeld, A., Henriksson, K., Steele, L., Neuhausen, S.L., Nussbaum, R., Beattie, M., Odunsi, K., Sucheston, L., Gayther, S.A., Nathanson, K., Gross, J., Walsh, C., Karlan, B., Chenevix-Trench, G., Easton, D.F. and Antoniou, A.C.
    Published:
    2012
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    21, (1)
    Page Range:
    134-147
    doi:
    10.1158/1055-9965.EPI-11-0775
  • Machine learning approaches for the discovery of gene-gene interactions in disease data - Upstill-Goddard, Rosanna, Eccles, Diana, Fliege, Jörg and Collins, Andrew
    Published:
    2012
    Publication:
    Briefings in Bioinformatics
  • Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 - Prokunina-Olsson, Ludmila, Kirchhoff, Tomas, Gaudet, Mia M., Antoniou, Antonis C., McGuffog, Lesley, Humphreys, Manjeet K., Dunning, Alison M., Bojesen, Stig E., Nordestgaard, Børge G., Flyger, Henrik, Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Ahn, Sei-Hyun, Dork, Thilo, Schürmann, Peter, Karstens, Johann H., Hillemanns, Peter, Couch, Fergus J., Olson, Janet, Vachon, Celine, Wang, Xianshu, Cox, Angela, Brock, Ian, Elliott, Graeme, Reed, Malcolm W.R., Burwinkel, Barbara, Meindl, Alfons, Brauch, Hiltrud, Hamann, Ute, Ko, Yon-Dschun, Broeks, Annegien, Schmidt, Marjanka K., Van ‘t Veer, Laura J., Braaf, Linde M., Johnson, Nichola, Fletcher, Olivia, Gibson, Lorna, Peto, Julian, Turnbull, Clare, Seal, Sheila, Renwick, Anthony, Rahman, Nazneen, Wu, Pei-Ei, Yu, Jyh-Cherng, Hsiung, Chia-Ni, Shen, Chen-Yang, Southey, Melissa C., Hopper, John L., Hammet, Fleur, Van Dorpe, Thijs, Dieudonne, Anne-Sophie, Hatse, Sigrid, Lambrechts, Diether, Andrulis, Irene L., Bogdanova, Natalia, Antonenkova, Natalia, Rogov, Juri I., Prokofieva, Daria, Bermisheva, Marina, Khusnutdinova, Elza, van Asperen, Christi J., Tollenaar, Robert A.E.M., Hooning, Maartje J., Devilee, Peter, Margolin, Sara, Lindblom, Annika, Milne, Roger L., Arias, José Ignacio, Zamora, M. Pilar, Benítez, Javier, Severi, Gianluca, Baglietto, Laura, Giles, Graham G., Group, AOCS Study, Spurdle, Amanda B., Beesley, Jonathan, Chen, Xiaoqing, Holland, Helene, Healey, Sue, Wang-Gohrke, Shan, Chang-Claude, Jenny, Mannermaa, Arto, Kosma, Veli-Matti, Kauppinen, Jaana, Kataja, Vesa, Agnarsson, Bjarni A., Caligo, Maria A., Godwin, Andrew K., Nevanlinna, Heli, Heikkinen, Tuomas, Fredericksen, Zachary, Lindor, Noralane, Nathanson, Katherine L., Domchek, Susan M., Loman, Niklas, Karlsson, Per, Askmalm, Marie Stenmark, Melin, Beatrice, von Wachenfeldt, Anna, Hogervorst, Frans B. L., Verheus, Martijn, Rookus, Matti A., Seynaeve, Caroline, Oldenburg, Rogier A., Ligtenberg, Marjolijn J., Ausems, Margreet G.E.M., Aalfs, Cora M., Gille, Hans J.P., Wijnen, Juul T., Gómez García, Encarna B., Peock, Susan, Cook, Margaret, Oliver, Clare T., Frost, Debra, Luccarini, Craig, Pichert, Gabriella, Davidson, Rosemarie, Chu, Carol, Eccles, Diana, Ong, Kai-Ren, Cook, Jackie, Douglas, Fiona, Hodgson, Shirley, Evans, D. Gareth, Eeles, Rosalind, Gold, Bert, Pharoah, Paul D.P., Offit, Kenneth, Chenevix-Trench, Georgia and Easton, Douglas F.
    Published:
    2012
    Publication:
    PLoS ONE
    Volume:
    7, (6)
    Page Range:
    e35706-[10pp]
    doi:
    10.1371/journal.pone.0035706
    PMID:
    22768030
  • Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. - Burn, John, Gerdes, Anne-Marie, Macrae, Finlay, Mecklin, Jukka-Pekka, Moeslein, Gabriela, Olschwang, Sylviane, Eccles, Diane, Evans, D Gareth, Maher, Eamonn R., Bertario, Lucio, Bisgaard, Marie-Luise, Dunlop, Malcolm G., Ho, Judy W. C., Hodgson, Shirley V., Lindblom, Annika, Lubinski, Jan, Morrison, Patrick J., Murday, Victoria, Ramesar, Raj, Side, Lucy, Scott, Rodney J., Thomas, Huw J. W., Vasen, Hans F., Barker, Gail, Crawford, Gillian, Elliott, Faye, Movahedi, Mohammad, Pylvanainen, Kirsi, Wijnen, Juul T., Fodde, Riccardo, Lynch, Henry T., Mathers, John C. and Bishop, D. Timothy
    Published:
    2011
    Publication:
    The Lancet
    Volume:
    378, (9809)
    Page Range:
    2081-2087
    doi:
    10.1016/S0140-6736(11)61049-0
    PMID:
    22541575
  • Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers - Cox, D.G., Simard, J., Sinnett, D., Hamdi, Y., Soucy, P., Ouimet, M., Barjhoux, L., Verny-Pierre, C., McGuffog, L., Healey, S., Szabo, C., Greene, M. H., Mai, P. L., Andrulis, I. L., Thomassen, M., Gerdes, A.-M., Caligo, M. A., Friedman, E., Laitman, Y., Kaufman, B., Paluch, S. S., Borg, A., Karlsson, P., Stenmark Askmalm, M., Barbany Bustinza, G., Nathanson, K. L., Domchek, S. M., Rebbeck, T. R., Benitez, J., Hamann, U., Rookus, M. A., van den Ouweland, A. M. W., Ausems, M. G. E. M., Aalfs, C. M., van Asperen, C. J., Devilee, P., Gille, H. J. J. P., Peock, S., Frost, D., Evans, D. G., Eeles, R., Izatt, L., Adlard, J., Paterson, J., Eason, J., Godwin, A. K., Remon, M.-A., Moncoutier, V., Gauthier-Villars, M., Lasset, C., Giraud, S., Hardouin, A., Berthet, P., Sobol, H., Eisinger, F., Bressac de Paillerets, B., Caron, O., Delnatte, C., Goldgar, D., Miron, A., Ozcelik, H., Buys, S., Southey, M. C., Terry, M. B., Singer, C. F., Dressler, A.-C., Tea, M.-K., Hansen, T. V. O., Johannsson, O., Piedmonte, M., Rodriguez, G. C., Basil, J. B., Blank, S., Toland, A. E., Montagna, M., Isaacs, C., Blanco, I., Gayther, S. A., Moysich, K. B., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Niederacher, D., Sutter, C., Gadzicki, D., Fiebig, B., Caldes, T., Laframboise, R., Nevanlinna, H., Chen, X., Beesley, J., Spurdle, A. B., Neuhausen, S. L., Ding, Y. C., Couch, F. J., Wang, X., Peterlongo, P., Manoukian, S., Bernard, L., Radice, P., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C., Stoppa-Lyonnet, D., Mazoyer, S., Sinilnikova, O. M., Dumont, M., Mai, P. L., Greene, M., Glendon, G., Selander, T., Weerasooriya, N., Karlsson, P., Nordling, M., Bergman, A., Einbeigi, Z., Stenmark-Askmalm, M., Liedgren, S., Borg, A., Loman, N., Olsson, H., Kristoffersson, U., Soller, M., Jernstrom, H., Harbst, K., Henriksson, K., Lindblom, A., Arver, B., von Wachenfeldt, A., Liljegren, A., Barbany-Bustinza, G., Rantala, J., Melin, B., Gronberg, H., Stattin, E.-L., Emanuelsson, M., Ehrencrona, H., Torres, D., Rashid, M. U., Seidel-Renkert, A., Hogervorst, F. B. L., Verhoef, S., Verheus, M., van't Veer, L. J., van Leeuwen, F. E., Rookus, M. A., Collee, M., van den Ouweland, A. M. W., Jager, A., Hooning, M. J., Tilanus-Linthorst, M. M. A., Seynaeve, C., van Asperen, C. J., Wijnen, J. T., Vreeswijk, M. P., Tollenaar, R. A., Devilee, P., Ligtenberg, M. J., Hoogerbrugge, N., Ausems, M. G., van der Luijt, R. B., Aalfs, C. M., van Os, T. A., Gille, J. J. P., Waisfisz, Q., Meijers-Heijboer, H. E. J., Gomez-Garcia, E. B., van Roozendaal, C. E., Blok, M. J., Caanen, B., Oosterwijk, J. C., van der Hout, A. H., Mourits, M. J., Vasen, H. F., Easton, D. F., Peock, S., Cook, M., Frost, D., Platte, R., Miedzybrodzka, Z., Gregory, H., Morrison, P., Jeffers, L., Cole, T., Ong, K.-r., Hoffman, J., Donaldson, A., James, M., Paterson, J., Downing, S., Taylor, A., Murray, A., Rogers, M. T., McCann, E., Kennedy, M. J., Barton, D., Porteous, M., Drummond, S., Brewer, C., Kivuva, E., Searle, A., Goodman, S., Hill, K., Davidson, R., Murday, V., Bradshaw, N., Snadden, L., Longmuir, M., Watt, C., Gibson, S., Haque, E., Tobias, E., Duncan, A., Izatt, L., Jacobs, C., Langman, C., Whaite, A., Dorkins, H., Barwell, J., Adlard, J., Chu, C., Miller, J., Ellis, I., Houghton, C., Evans, D. G., Lalloo, F., Taylor, J., Side, L., Male, A., Berlin, C., Eason, J., Collier, R., Douglas, F., Claber, O., Jobson, I., Walker, L., McLeod, D., Halliday, D., Durell, S., Stayner, B., Eeles, R., Shanley, S., Rahman, N., Houlston, R., Bancroft, E., D'Mello, L., Page, E., Ardern-Jones, A., Kohut, K., Wiggins, J., Castro, E., Mitra, A., Robertson, L., Cook, J., Quarrell, O., Bardsley, C., Hodgson, S., Goff, S., Brice, G., Winchester, L., Eddy, C., Tripathi, V., Attard, V., Eccles, D., Lucassen, A., Crawford, G., McBride, D., Smalley, S., Evans, D. G., Lalloo, F., Eeles, R., Bancroft, E., D'Mello, L., Sinilnikova, O., Barjhoux, L., Verny-Pierre, C., Giraud, S., Leone, M., Mazoyer, S., Stoppa-Lyonnet, D., Gauthier-Villars, M., Buecher, B., Houdayer, C., Moncoutier, V., Belotti, M., Tirapo, C., de Pauw, A., Bressac-de-Paillerets, B., Remenieras, A., Byrde, V., Caron, O., Lenoir, G., Bignon, Y.-J., Uhrhammer, N., Lasset, C., Bonadona, V., Hardouin, A., Berthet, P., Sobol, H., Bourdon, V., Noguchi, T., Eisinger, F., Coulet, F., Colas, C., Soubrier, F., Coupier, I., Pujol, P., Peyrat, J.-P., Fournier, J., Revillion, F., Vennin, P., Adenis, C., Rouleau, E., Lidereau, R., Demange, L., Nogues, C., Muller, D., Fricker, J.-P., Longy, M., Sevenet, N., Toulas, C., Guimbaud, R., Gladieff, L., Feillel, V., Leroux, D., Dreyfus, H., Rebischung, C., Coron, F., Faivre, L., Prieur, F., Lebrun, M., Ferrer, S. F., Frenay, M., Venat-Bouvet, L., Delnatte, C., Mortemousque, I., Lynch, H. T., Snyder, C. L., Ejlertsen, B., Andersen, M. K., Kjaergaard, S., Senter, L., Sweet, K., O'Connor, M., Craven, C., Pharoah, P., Ramus, S., Pye, C., Harrington, P., Wozniak, E., Varon-Mateeva, R., Kast, K., Preisler-Adams, S., Deissler, H., Schonbuchner, I., Heinritz, W., Schafer, D., Aittomaki, K., Blomqvist, C., Heikkinen, T., Erkkila, R. N. I., Thorne, H., Niedermayr, E., de la Hoya, M. and Perez-Segura, P.
    Published:
    2011
    Publication:
    Human Molecular Genetics
    Volume:
    20, (23)
    Page Range:
    4732-4747
    doi:
    10.1093/hmg/ddr388
    PMID:
    21890493
  • Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer - Ashworth, Alan, Maxwell, Christopher A., Benítez, Javier, Gómez-Baldó, Laia, Osorio, Ana, Bonifaci, Núria, Fernández-Ramires, Ricardo, Costes, Sylvain V., Guinó, Elisabet, Chen, Helen, Evans, Gareth J. R., Mohan, Pooja, Català, Isabel, Petit, Anna, Aguilar, Helena, Villanueva, Alberto, Aytes, Alvaro, Serra-Musach, Jordi, Rennert, Gad, Lejbkowicz, Flavio, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Ripamonti, Carla B., Bonanni, Bernardo, Viel, Alessandra, Allavena, Anna, Bernard, Loris, Radice, Paolo, Friedman, Eitan, Kaufman, Bella, Laitman, Yael, Dubrovsky, Maya, Milgrom, Roni, Jakubowska, Anna, Cybulski, Cezary, Gorski, Bohdan, Jaworska, Katarzyna, Durda, Katarzyna, Sukiennicki, Grzegorz, Lubiński, Jan, Shugart, Yin Yao, Domchek, Susan M., Letrero, Richard, Weber, Barbara L., Hogervorst, Frans B. L., Rookus, Matti A., Collee, J. Margriet, Devilee, Peter, Ligtenberg, Marjolijn J., van der Luijt, Rob B., Aalfs, Cora M., Waisfisz, Quinten, Wijnen, Juul, van Roozendaal, Cornelis E. P., Easton, Douglas F., Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Harrington, Patricia, Evans, D. Gareth, Lalloo, Fiona, Eeles, Rosalind, Izatt, Louise, Chu, Carol, Eccles, Diana, Douglas, Fiona, Brewer, Carole, Nevanlinna, Heli, Heikkinen, Tuomas, Couch, Fergus J., Lindor, Noralane M., Wang, Xianshu, Godwin, Andrew K., Caligo, Maria A., Lombardi, Grazia, Loman, Niklas, Karlsson, Per, Ehrencrona, Hans, von Wachenfeldt, Anna, Bjork Barkardottir, Rosa, Hamann, Ute, Rashid, Muhammad U., Lasa, Adriana, Caldés, Trinidad, Andrés, Raquel, Schmitt, Michael, Assmann, Volker, Stevens, Kristen, Offit, Kenneth, Curado, João, Tilgner, Hagen, Guigó, Roderic, Aiza, Gemma, Brunet, Joan, Castellsagué, Joan, Martrat, Griselda, Urruticoechea, Ander, Blanco, Ignacio, Tihomirova, Laima, Goldgar, David E., Buys, Saundra, John, Esther M., Miron, Alexander, Southey, Melissa, Daly, Mary B., Schmutzler, Rita K., Wappenschmidt, Barbara, Meindl, Alfons, Arnold, Norbert, Deissler, Helmut, Varon-Mateeva, Raymonda, Sutter, Christian, Niederacher, Dieter, Imyamitov, Evgeny, Sinilnikova, Olga M., Stoppa-Lyonne, Dominique, Mazoyer, Sylvie, Verny-Pierre, Carole, Castera, Laurent, de Pauw, Antoine, Bignon, Yves-Jean, Uhrhammer, Nancy, Peyrat, Jean-Philippe, Vennin, Philippe, Fert Ferrer, Sandra, Collonge-Rame, Marie-Agnès, Mortemousque, Isabelle, Spurdle, Amanda B., Beesley, Jonathan, Chen, Xiaoqing, Healey, Sue, Barcellos-Hoff, Mary Helen, Vidal, Marc, Gruber, Stephen B., Lázaro, Conxi, Capellá, Gabriel, McGuffog, Lesley, Nathanson, Katherine L., Antoniou, Antonis C., Chenevix-Trench, Georgia, Fleisch, Markus C., Moreno, Víctor and Pujana, Miguel Angel
    Published:
    2011
    Publication:
    PLoS Biology
    Volume:
    9, (11)
    Page Range:
    e1001199-[18pp]
    doi:
    10.1371/journal.pbio.1001199
    PMID:
    22110403
  • Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 - Mulligan, Anna Marie, Couch, Fergus J., Barrowdale, Daniel, Domchek, Susan M., Eccles, Diana, Nevanlinna, Heli, Ramus, Susan J., Robson, Mark, Sherman, Mark, Spurdle, Amanda B., Wappenschmidt, Barbara, Lee, Andrew, McGuffog, Lesley, Healey, Sue, Sinilnikova, Olga M., Janavicius, Ramunas, Hansen, Thomas vO., Nielsen, Finn C., Ejlertsen, Bent, Osorio, Ana, Muñoz-Repeto, Iván, Durán, Mercedes, Godino, Javier, Pertesi, Maroulio, Benítez, Javier, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Cattaneo, Elisa, Bonanni, Bernardo, Viel, Alessandra, Pasini, Barbara, Papi, Laura, Ottini, Laura, Savarese, Antonella, Bernard, Loris, Radice, Paolo, Hamann, Ute, Verheus, Martijn, Meijers-Heijboer, Hanne E.J., Wijnen, Juul, Gómez García, Encarna B., Nelen, Marcel R., Kets, C. Marleen, Seynaeve, Caroline, Tilanus-Linthorst, Madeleine M.A., van der Luijt, Rob B., Os, Theo, Rookus, Matti, Frost, Debra, Jones, J. Louise, Evans, D. Gareth, Lalloo, Fiona, Eeles, Ros, Izatt, Louise, Adlard, Julian, Davidson, Rosemarie, Cook, Jackie, Donaldson, Alan, Dorkins, Huw, Gregory, Helen, Eason, Jacqueline, Houghton, Catherine, Barwell, Julian, Side, Lucy E., McCann, Emma, Murray, Alex, Peock, Susan, Godwin, Andrew K., Schmutzler, Rita K., Rhiem, Kerstin, Engel, Christoph, Meindl, Alfons, Ruehl, Ina, Arnold, Norbert, Niederacher, Dieter, Sutter, Christian, Deissler, Helmut, Gadzicki, Dorothea, Kast, Karin, Preisler-Adams, Sabine, Varon-Mateeva, Raymonda, Schoenbuchner, Ines, Fiebig, Britta, Heinritz, Wolfram, Schäfer, Dieter, Gevensleben, Heidrun, Caux-Moncoutier, Virginie, Fassy-Colcombet, Marion, Cornelis, François, Mazoyer, Sylvie, Léoné, Mélanie, Boutry-Kryza, Nadia, Hardouin, Agnès, Berthet, Pascaline, Muller, Danièle, Fricker, Jean-Pierre, Mortemousque, Isabelle, Pujol, Pascal, Coupier, Isabelle, Lebrun, Marine, Kientz, Caroline, Longy, Michel, Sevenet, Nicolas, Stoppa-Lyonnet, Dominique, Isaacs, Claudine, Caldes, Trinidad, de la Hoya, Miguel, Heikkinen, Tuomas, Aittomäki, Kristiina, Blanco, Ignacio, Lazaro, Conxi, Barkardottir, Rosa B., Soucy, Penny, Dumont, Martine, Simard, Jacques, Montagna, Marco, Tognazzo, Silvia, D'Andrea, Emma, Fox, Stephen, Yan, Max, Rebbeck, Tim, Olopade, Olufunmilayo I., Weitzel, Jeffrey N., Lynch, Henry T., Ganz, Patricia A., Tomlinson, Gail E., Wang, Xianshu, Fredericksen, Zachary, Pankratz, Vernon S., Lindor, Noralane M., Szabo, Csilla, Offit, Kenneth, Sakr, Rita, Gaudet, Mia, Bhatia, Jasmine, Kauff, Noah, Singer, Christian F., Tea, Muy-Kheng, Gschwantler-Kaulich, Daphne, Fink-Retter, Anneliese, Mai, Phuong L., Greene, Mark H., Imyanitov, Evgeny, O'Malley, Frances P., Ozcelik, Hilmi, Glendon, Gordon, Toland, Amanda E., Gerdes, Anne-Marie, Thomassen, Mads, Kruse, Torben A., Jensen, Uffe, Skytte, Anne-Bine, Caligo, Maria A., Soller, Maria, Henriksson, Karin, Wachenfeldt, von Anna, Arver, Brita, Stenmark-Askmalm, Marie, Karlsson, Per, Ding, Yuan, Neuhausen, Susan L., Beattie, Mary, Pharoah, Paul D.P., Moysich, Kirsten B., Nathanson, Katherine L., Karlan, Beth Y., Gross, Jenny, John, Esther M., Daly, Mary B., Buys, Saundra M., Southey, Melissa C., Hopper, John L., Terry, Mary, Chung, Wendy, Miron, Alexander F., Goldgar, David, Chenevix-Trench, Georgia, Easton, Douglas F., Andrulis, Irene L. and Antoniou, Antonis C.
    Published:
    2011
    Publication:
    Breast Cancer Research
    Volume:
    13, (6)
    Page Range:
    R110
    doi:
    10.1186/bcr3052
    PMID:
    22053997
  • A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer - Haiman, Christopher A., Chen, Gary K., Vachon, Celine M., Canzian, Federico, Dunning, Alison, Millikan, Robert C., Wang, Xianshu, Ademuyiwa, Foluso, Ahmed, Shahana, Ambrosone, Christine B., Baglietto, Laura, Balleine, Rosemary, Bandera, Elisa V., Beckmann, Matthias W., Berg, Christine D., Bernstein, Leslie, Blomqvist, Carl, Blot, William J., Brauch, Hiltrud, Buring, Julie E., Carey, Lisa A., Carpenter, Jane E., Chang-Claude, Jenny, Chanock, Stephen J., Chasman, Daniel I., Clarke, Christine L., Cox, Angela, Cross, Simon S., Deming, Sandra L., Diasio, Robert B., Dimopoulos, Athanasios M., Driver, W. Ryan, Dünnebier, Thomas, Durcan, Lorraine, Eccles, Diana, Edlund, Christopher K., Ekici, Arif B., Fasching, Peter A., Feigelson, Heather S., Flesch-Janys, Dieter, Fostira, Florentia, Försti, Asta, Fountzilas, George, Gerty, Susan M., Giles, Graham G., Godwin, Andrew K., Goodfellow, Paul, Graham, Nikki, Greco, Dario, Hamann, Ute, Hankinson, Susan E., Hartmann, Arndt, Hein, Rebecca, Heinz, Judith, Holbrook, Andrea, Hoover, Robert N., Hu, Jennifer J., Hunter, David J., Ingles, Sue A., Irwanto, Astrid, Ivanovich, Jennifer, John, Esther M., Johnson, Nicola, Jukkola-Vuorinen, Arja, Kaaks, Rudolf, Ko, Yon-Dschun, Kolonel, Laurence N., Konstantopoulou, Irene, Kosma, Veli-Matti, Kulkarni, Swati, Lambrechts, Diether, Lee, Adam M., Marchand, Loïc Le, Lesnick, Timothy, Liu, Jianjun, Lindstrom, Sara, Mannermaa, Arto, Margolin, Sara, Martin, Nicholas G., Miron, Penelope, Montgomery, Grant W., Nevanlinna, Heli, Nickels, Stephan, Nyante, Sarah, Olswold, Curtis, Palmer, Julie, Pathak, Harsh, Pectasides, Dimitrios, Perou, Charles M., Peto, Julian, Pharoah, Paul D.P., Pooler, Loreall C., Press, Michael F., Pylkäs, Katri, Rebbeck, Timothy R., Rodriguez-Gil, Jorge L., Rosenberg, Lynn, Ross, Eric, Rüdiger, Thomas, Silva, Isabel dos Santos, Sawyer, Elinor, Schmidt, Marjanka K., Schulz-Wendtland, Rüdiger, Schumacher, Fredrick, Severi, Gianluca, Sheng, Xin, Signorello, Lisa B., Sinn, Hans-Peter, Stevens, Kristen N., Southey, Melissa C., Tapper, William J., Tomlinson, Ian, Hogervorst, Frans B.L., Wauters, Els, Weaver, JoEllen, Wildiers, Hans, Winqvist, Robert, Berg, David Van Den, Wan, Peggy, Xia, Lucy Y., Yannoukakos, Drakoulis, Zheng, Wei, Ziegler, Regina G., Siddiq, Afshan, Slager, Susan L., Stram, Daniel O., Easton, Douglas, Kraft, Peter, Henderson, Brian E. and Couch, Fergus J.
    Published:
    2011
    Publication:
    Nature Genetics
    Volume:
    43, (12)
    Page Range:
    1210-1214
    doi:
    10.1038/ng.985
  • Common breast cancer susceptibility loci are associated with triple-negative breast cancer - Stevens, Kristen N., Vachon, Celine M., Lee, Adam M., Slager, Susan, Lesnick, Timothy, Olswold, Curtis, Fasching, Peter A., Miron, Penelope, Eccles, Diana, Carpenter, Jane E., Godwin, Andrew K., Ambrosone, Christine, Winqvist, Robert, Brauch, Hiltrud, Schmidt, Marjanka K., Cox, Angela, Cross, Simon S., Sawyer, Elinor, Hartmann, Arndt, Beckmann, Matthias W., Schulz-Wendtland, Rüdiger, Ekici, Arif B., Tapper, William J., Gerty, Susan M., Durcan, Lorraine, Graham, Nikki J., Hein, Rebecca, Nickels, Stephan, Flesch-Janys, Dieter, Heinz, Judith, Sinn, Hans-Peter, Konstantopoulou, Irene, Fostira, Florentia, Pectasides, Dimitrios, Dimopoulos, Athanasios M., Fountzilas, George, Clarke, Christine L., Balleine, Rosemary, Olson, Janet E., Fredericksen, Zachary, Diasio, Robert B., Pathak, Harsh, Ross, Eric, Weaver, JoEllen, Rüdiger, Thomas, Forsti, Asta, Dünnebier, Thomas, Ademuyiwa, Foluso, Kulkarni, Swati, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Ko, Yon-Dschun, Van Limbergen, Erik , Janssen, Hilde, Peto, Julian, Fletcher, Olivia, Giles, Graham G., Baglietto, Laura, Verhoef, Senno, Tomlinson, Ian, Kosma, Veli-Matti, Beesley, Jonathan, Greco, Dario, Blomqvist, Carl, Irwanto, Astrid, Liu, Jianjun, Blows, Fiona M., Dawson, Sarah-Jane, Margolin, Sara, Mannermaa, Arto, Martin, Nicholas G., Montgomery, Grant W., Lambrechts, Diether, dos Santos Silva, Isabel , Severi, Gianluca, Hamann, Ute, Pharoah, Paul, Easton, Douglas F., Chang-Claude, Jenny, Yannoukakos, Drakoulis, Nevanlinna, Heli, Wang, Xianshu and Couch, Fergus J.
    Published:
    2011
    Publication:
    Cancer Research
    Volume:
    71, (19)
    Page Range:
    6240-6249
    doi:
    10.1158/0008-5472.CAN-11-1266
    PMID:
    21844186
  • Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids - Robanus-Maandag, Els, Bosch, Cathy, Amini-Nik, Saeid, Knijnenburg, Jeroen, Szuhai, Karoly, Cervera, Pascale, Poon, Raymond, Eccles, Diana, Radice, Paolo, Giovannini, Marco, Alman, Benjamin, Tejpar, Sabine, Devilee, Peter and Fodde, Riccardo
    Published:
    2011
    Publication:
    PLoS ONE
    Volume:
    6, (9)
    Page Range:
    e24354
    doi:
    10.1371/journal.pone.0024354
    PMID:
    21931686
  • Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers - Antoniou, A.C., Kartsonaki, C., Sinilnikova, O.M., Soucy, P., McGuffog, L., Healey, S., Lee, A., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Barile, M., Pensotti, V., Pasini, B., Dolcetti, R., Giannini, G., Laura Putignano, A., Varesco, L., Radice, P., Mai, P.L., Greene, M.H., Andrulis, I.L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A.-M., Kruse, T.A., Birk Jensen, U., Cruger, D.G., Caligo, M.A., Laitman, Y., Milgrom, R., Kaufman, B., Paluch-Shimon, S., Friedman, E., Loman, N., Harbst, K., Lindblom, A., Arver, B., Ehrencrona, H., Melin, B., Nathanson, K.L., Domchek, S.M., Rebbeck, T., Jakubowska, A., Lubinski, J., Gronwald, J., Huzarski, T., Byrski, T., Cybulski, C., Gorski, B., Osorio, A., Ramon y Cajal, T., Fostira, F., Andres, R., Benitez, J., Hamann, U., Hogervorst, F.B., Rookus, M.A., Hooning, M.J., Nelen, M.R., van der Luijt, R.B., van Os, T.A.M., van Asperen, C.J., Devilee, P., Meijers-Heijboer, H.E.J., Gomez Garcia, E.B., Peock, S., Cook, M., Frost, D., Platte, R., Leyland, J., Gareth Evans, D., Lalloo, F., Eeles, R., Izatt, L., Adlard, J., Davidson, R., Eccles, D., Ong, K.-r., Cook, J., Douglas, F., Paterson, J., John Kennedy, M., Miedzybrodzka, Z., Godwin, A., Stoppa-Lyonnet, D., Buecher, B., Belotti, M., Tirapo, C., Mazoyer, S., Barjhoux, L., Lasset, C., Leroux, D., Faivre, L., Bronner, M., Prieur, F., Nogues, C., Rouleau, E., Pujol, P., Coupier, I., Frenay, M., Hopper, J.L., Daly, M.B., Terry, M.B., John, E.M., Buys, S.S., Yassin, Y., Miron, A., Goldgar, D., Singer, C.F., Tea, M.-K., Pfeiler, G., Catharina Dressler, A., Hansen, T.v.O., Jonson, L., Ejlertsen, B., Bjork Barkardottir, R., Kirchhoff, T., Offit, K., Piedmonte, M., Rodriguez, G., Small, L., Boggess, J., Blank, S., Basil, J., Azodi, M., Ewart Toland, A., Montagna, M., Tognazzo, S., Agata, S., Imyanitov, E., Janavicius, R., Lazaro, C., Blanco, I., Pharoah, P.D.P., Sucheston, L., Karlan, B.Y., Walsh, C.S., Olah, E., Bozsik, A., Teo, S.-H., Seldon, J.L., Beattie, M.S., van Rensburg, E.J., Sluiter, M.D., Diez, O., Schmutzler, R.K., Wappenschmidt, B., Engel, C., Meindl, A., Ruehl, I., Varon-Mateeva, R., Kast, K., Deissler, H., Niederacher, D., Arnold, N., Gadzicki, D., Schonbuchner, I., Caldes, T., de la Hoya, M., Nevanlinna, H., Aittomaki, K., Dumont, M., Chiquette, J., Tischkowitz, M., Chen, X., Beesley, J., Spurdle, A.B., Neuhausen, S.L., Chun Ding, Y., Fredericksen, Z., Wang, X., Pankratz, V.S., Couch, F., Simard, J., Easton, D.F. and Chenevix-Trench, G.
    Published:
    2011
    Publication:
    Human Molecular Genetics
    Volume:
    20, (16)
    Page Range:
    3304-3321
    doi:
    10.1093/hmg/ddr226
  • Germline mutations in RAD51D confer susceptibility to ovarian cancer - Loveday, Chey, Turnbull, Clare, Ramsay, Emma, Hughes, Deborah, Ruark, Elise, Frankum, Jessica R., Bowden, Georgina, Kalmyrzaev, Bolot, Warren-Perry, Margaret, Snape, Katie, Adlard, Julian W., Barwell, Julian, Berg, Jonathan, Brady, Angela F., Brewer, Carole, Brice, Glen, Chapman, Cyril, Cook, Jackie, Davidson, Rosemarie, Donaldson, Alan, Douglas, Fiona, Greenhalgh, Lynn, Henderson, Alex, Izatt, Louise, Kumar, Ajith, Lalloo, Fiona, Miedzybrodzka, Zosia, Morrison, Patrick J., Paterson, Joan, Porteous, Mary, Rogers, Mark T, Shanley, Susan, Walker, Lisa, Eccles, Diana, Evans, D. Gareth, Renwick, Anthony, Seal, Sheila, Lord, Christopher J., Ashworth, Alan, Reis-Filho, Jorge S., Antoniou, Antonis C. and Rahman, Nazneen
    Published:
    2011
    Publication:
    Nature Genetics
    Volume:
    43, (9)
    Page Range:
    879-882
    doi:
    10.1038/ng.893
  • Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancer - Evans, D.G., Howell, A., Ward, D., Lalloo, F., Jones, J.L. and Eccles, Diana
    Published:
    2011
    Publication:
    Journal of Medical Genetics
    Volume:
    48, (8)
    Page Range:
    520-522
    doi:
    10.1136/jmedgenet-2011-100006
    PMID:
    21653198
  • Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the ovarian cancer association consortium - Minna, John D., Amankwah, Ernest K., Wang, Qinggang, Schildkraut, Joellen M., Tsai, Ya-Yu, Ramus, Susan J., Fridley, Brooke L., Beesley, Jonathan, Johnatty, Sharon E., Webb, Penelope M., Chenevix-Trench, Georgia, Dale, Laura C., Lambrechts, Diether, Amant, Frederic, Despierre, Evelyn, Vergote, Ignace, Gayther, Simon A., Gentry-Maharaj, Aleksandra, Menon, Usha, Chang-Claude, Jenny, Wang-Gohrke, Shan, Anton-Culver, Hoda, Ziogas, Argyrios, Dörk, Thilo, Dürst, Matthias, Antonenkova, Natalia, Bogdanova, Natalia, Brown, Robert, Flanagan, James M., Kaye, Stanley B., Paul, James, Bützow, Ralf, Nevanlinna, Heli, Campbell, Ian, Eccles, Diana M., Karlan, Beth Y., Gross, Jenny, Walsh, Christine, Pharoah, Paul D. P., Song, Honglin, Krüger Kjær, Susanne, Høgdall, Estrid, Høgdall, Claus, Lundvall, Lene, Nedergaard, Lotte, Kiemeney, Lambertus A. L. M., Massuger, Leon F. A. G., van Altena, Anne M., Vermeulen, Sita H. H. M., Le, Nhu D., Brooks-Wilson, Angela, Cook, Linda S., Phelan, Catherine M., Cunningham, Julie M., Vachon, Celine M., Vierkant, Robert A., Iversen, Edwin S., Berchuck, Andrew, Goode, Ellen L., Sellers, Thomas A. and Kelemen, Linda E.
    Published:
    2011
    Publication:
    PLoS ONE
    Volume:
    6, (5)
    Page Range:
    e19642-[10pp]
    doi:
    10.1371/journal.pone.0019642
    PMID:
    21637745
  • A randomized placebo-controlled prevention trial of aspirin and/or resistant starch in young people with familial adenomatous polyposis - Burn, J., Bishop, D.T., Chapman, P.D., Elliott, F., Bertario, L., Dunlop, M.G., Eccles, D., Ellis, A., Evans, D.G., Fodde, R., Maher, E.R., Moslein, G., Vasen, H.F.A., Coaker, J., Phillips, R.K.S., Bulow, S. and Mathers, J. C.
    Published:
    2011
    Publication:
    Cancer Prevention Research
    Volume:
    4, (5)
    Page Range:
    655
    doi:
    10.1158/1940-6207.CAPR-11-0106
  • Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers - Spurdle, Amanda B., Marquart, Louise, McGuffog, Lesley, Healey, Sue, Sinilnikova, Olga, Wan, Fei, Chen, Xiaoqing, Beesley, Jonathan, Singer, Christian F., Dressler, Anne-Catharine, Gschwantler-Kaulich, Daphne, Blum, Joanne L., Tung, Nadine, Weitzel, Jeff, Lynch, Henry, Garber, Judy, Easton, Douglas F., Peock, Susan, Cook, Margaret, Oliver, Clare T., Frost, Debra, Conroy, Don, Evans, D. Gareth, Lalloo, Fiona, Eeles, Ros, Izatt, Louise, Davidson, Rosemarie, Chu, Carol, Eccles, Diana, Selkirk, Christina G., Daly, Mary, Isaacs, Claudine, Stoppa-Lyonnet, Dominique, Sinilnikova, Olga M., Buecher, Bruno, Belotti, Muriel, Mazoyer, Sylvie, Barjhoux, Laure, Verny-Pierre, Carole, Lasset, Christine, Dreyfus, Hélène, Pujol, Pascal, Collonge-Rame, Marie-Agnès, Rookus, Matti A., Verhoef, Senno, Kriege, Mieke, Hoogerbrugge, Nicoline, Ausems, Margaret G. E. M., van Os, Theo A., Wijnen, Juul, Devilee, Peter, Meijers-Heijboer, Hanne E. J., Blok, Marinus J., Heikkinen, Tuomas, Nevanlinna, Heli, Jakubowska, Anna, Lubinski, Jan, Huzarski, Tomasz, Byrski, Tomasz, Durocher, Francine, Couch, Fergus J., Lindor, Noralene M., Wang, Xianshu, Thomassen, Mads, Domchek, Susan, Nathanson, Kate, Caligo, M. A., Jernstrom, Helena, Liljegren, Annelie, Ehrencrona, Hans, Karlsson, Per, Ganz, Patricia A., Olopade, Olufunmilayo I., Tomlinson, Gail, Neuhausen, Susan, Antoniou, Antonis C., Chenevix-Trench, Georgia and Rebbeck, Timothy R.
    Published:
    2011
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    20, (5)
    Page Range:
    1032-1038
    doi:
    10.1158/1055-9965.EPI-10-0909
    PMID:
    21393566
  • Composite likelihood-based meta-analysis of breast cancer association studies - Politopoulos, Ioannis, Gibson, Jane, Tapper, William, Ennis, Sarah, Eccles, Diana and Collins, Andrew
    Published:
    2011
    Publication:
    Journal of Human Genetics
    Volume:
    56, (5)
    Page Range:
    377-382
    doi:
    10.1038/jhg.2011.23
    PMID:
    21390041
  • Prediction of single-nucleotide substitutions that result in exon skipping: identification of a splicing silencer in BRCA1 exon 6 - Raponi, Michela, Kralovicova, Jana, Copson, Ellen, Divina, Petr, Eccles, Diana, Johnson, Peter, Baralle, Diana and Vorechovsky, Igor
    Published:
    2011
    Publication:
    Human Mutation
    Volume:
    32, (4)
    Page Range:
    436-444
    doi:
    10.1002/humu.21458
    PMID:
    21309043
  • Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers: results from the consortium of investigators of modifiers of BRCA1/BRCA2 - Osorio, A., Milne, R.L., Alonso, R., Pita, G., Peterlongo, P., Teulé, A., Nathanson, K.L., Domchek, S.M., Rebbeck, T., Lasa, A., Konstantopoulou, I., Hogervorst, F.B., Verhoef, S., van Dooren, M.F., Jager, A., Ausems, M.G.E.M., Aalfs, C.M., van Asperen, C.J., Vreeswijk, M., Waisfisz, Q., Van Roozendaal, C.E., Ligtenberg, M.J., Easton, D.F., Peock, S., Cook, M., Oliver, C.T., Frost, D., Curzon, B., Evans, D.G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Adlard, J., Eccles, D., Ong, K.-r., Douglas, F., Downing, S., Brewer, C., Walker, L., Nevanlinna, H., Aittomäki, K., Couch, F.J., Fredericksen, Z., Lindor, N.M., Godwin, A., Isaacs, C., Caligo, M.A., Loman, N., Jernström, H., Barbany-Bustinza, G., Liljegren, A., Ehrencrona, H., Stenmark-Askmalm, M., Feliubadaló, L., Manoukian, S., Peissel, B., Zaffaroni, D., Bonanni, B., Fortuzzi, S., Johannsson, O.T., Chenevix-Trench, G., Chen, X.-C., Beesley, J., Spurdle, A.B., Sinilnikova, O.M., Healey, S., McGuffog, L., Antoniou, A.C., Brunet, J., Radice, P. and Benítez, J.
    Published:
    2011
    Publication:
    British Journal of Cancer
    Volume:
    104, (8)
    Page Range:
    1356-1361
    doi:
    10.1038/bjc.2011.91
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing - Pharoah, P.D.P., Palmieri, R.T., Ramus, S.J., Gayther, S.A., Andrulis, I.L., Anton-Culver, H.A., Antonenkova, N., Antoniou, A.C., Beattie, M.S., Beckmann, M., Birrer, M.J., Bogdanova, N., Bolton, K.L., Brewster, W., Brooks-Wilson, A., Brown, R., Butzow, R., Caldes, T., Caligo, M.A., Campbell, I.G., Chang-Claude, J., Chen, A., Chenevix-Trench, G., Cook, L.S., Couch, F.J., Cramer, D.W., Cunningham, J.M., Despierre, E., Doherty, J.A., Dork, T., Durst, M., Eccles, Diana, Ekici, A.B., Fasching, P.A., de Fazio, A., Fenstermacher, D.A., Flanagan, J.M., Fridley, B.L., Friedman, E., Gao, B., Gentry-Maharaj, A., Godwin, A.K., Goode, E., Goodman, M.T., Gross, J., Hansen, T.V.O., Harnett, P.R., Heikkinen, T., Hein, R., Hogdall, C K., Hogdall, E.V., Iversen, E., Jakubowska, A., Johnatty, S.E., Karlan, B.Y., Kauff, N.D., Kaye, S.B., Kelemen, L.E., Kiemeney, L.A., Kjaer, S.K., Lambrechts, D., LaPolla, J.P., Lazaro, C., Le, N.D., Leminen, A., Leunen, K., Levine, D.A., Lu, Y., Lundvall, L., Macgregor, S., Marees, T., Massuger, L., McLaughlin, J.R., Menon, U., Montagna, M., Moysich, K.B., Narod, S., Nathanson, K.L., Nedergaard, L., Ness, R.B., Nevanlinna, H.A., Nickels, S., Osorio, A., Paul, J., Pearce, C.L., Phelan, C.M., Pike, M.C., Radice, P., Rossing, M.A., Schildkraut, J., Sellers, T.A., Singer, C.F., Song, H., Stram, D.O., Sutphen, R., Terry, K.L., Tsai, Y-Y., van Altena, A.M., Vergote, I., Vierkant, R.A., Vitonis, A.F., Walsh, C., Wang-Gohrke, S., Wappenschmidt, B., Wu, A.H., Ziogas, A., Berchuck, A. and Risch, H.A.
    Published:
    2011
    Publication:
    Clinical Cancer Research
    doi:
    10.1158/1078-0432.CCR-10-3405
    PMID:
    21385923
  • Genome-wide association of breast cancer: composite likelihood with imputed genotypes - Politopoulos, Ioannis, Gibson, Jane, Tapper, William, Ennis, Sarah, Eccles, Diana and Collins, Andrew
    Published:
    2011
    Publication:
    European Journal of Human Genetics
    Volume:
    19, (2)
    Page Range:
    194-199
    doi:
    10.1038/ejhg.2010.157
    PMID:
    20959865
  • Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study - Kempers, Marlies JE, Kuiper, Roland P, Ockeloen, Charlotte W, Chappuis, Pierre O, Hutter, Pierre, Rahner, Nils, Schackert, Hans K, Steinke, Verena, Holinski-Feder, Elke, Morak, Monika, Eccles, Diana M. and Other authors, 31
    Published:
    2011
    Publication:
    The Lancet Oncology
    Volume:
    12, (1)
    Page Range:
    49-55
    doi:
    10.1016/S1470-2045(10)70265-5
    PMID:
    21145788
  • Validating “Image box”-a new approach to multicentre radiology reviews using a web-based image review system: study protocol - Moyle, Penelope Laura, Katako, Masako, Wheeler, Kevin, Gerty, Susan, Morrish, Oliver, Wallis, Matthew G., Eccles, Diana M. and Warren, Ruth
    Published:
    2011
    Publication:
    Journal of Biomedical Graphics and Computing
    Volume:
    1, (1)
    Page Range:
    24-32
    doi:
    10.5430/jbgc.v1n1p24
  • Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium Studies - Yang, X.R., Chang-Claude, J., Goode, E.L., Couch, F.J., Nevanlinna, H., Milne, R. L., Gaudet, M., Schmidt, M. K., Broeks, A., Cox, A., Fasching, P. A., Hein, R., Spurdle, A. B., Blows, F., Driver, K., Flesch-Janys, D., Heinz, J., Sinn, P., Vrieling, A., Heikkinen, T., Aittomaki, K., Heikkila, P., Blomqvist, C., Lissowska, J., Peplonska, B., Chanock, S., Figueroa, J., Brinton, L., Hall, P., Czene, K., Humphreys, K., Darabi, H., Liu, J., Van 't Veer, L. J., van Leeuwen, F. E., Andrulis, I. L., Glendon, G., Knight, J. A., Mulligan, A. M., O'Malley, F. P., Weerasooriya, N., John, E. M., Beckmann, M. W., Hartmann, A., Weihbrecht, S. B., Wachter, D. L., Jud, S. M., Loehberg, C. R., Baglietto, L., English, D. R., Giles, G. G., McLean, C. A., Severi, G., Lambrechts, D., Vandorpe, T., Weltens, C., Paridaens, R., Smeets, A., Neven, P., Wildiers, H., Wang, X., Olson, J. E., Cafourek, V., Fredericksen, Z., Kosel, M., Vachon, C., Cramp, H. E., Connley, D., Cross, S. S., Balasubramanian, S. P., Reed, M. W. R., Dork, T., Bremer, M., Meyer, A., Karstens, J. H., Ay, A., Park-Simon, T.-W., Hillemanns, P., Arias Perez, J. I., Rodriguez, P. M., Zamora, P., Benitez, J., Ko, Y.-D., Fischer, H.-P., Hamann, U., Pesch, B., Bruning, T., Justenhoven, C., Brauch, H., Eccles, D. M., Tapper, W.J., Gerty, S.M., Sawyer, E. J., Tomlinson, I. P., Jones, A., Kerin, M., Miller, N., McInerney, N., Anton-Culver, H., Ziogas, A., Shen, C.-Y., Hsiung, C.-N., Wu, P.-E., Yang, S.-L., Yu, J.-C., Chen, S.-T., Hsu, G.-C., Haiman, C. A., Henderson, B. E., Le Marchand, L., Kolonel, L. N., Lindblom, A., Margolin, S., Jakubowska, A., Lubinski, J., Huzarski, T., Byrski, T., Gorski, B., Gronwald, J., Hooning, M. J., Hollestelle, A., van den Ouweland, A. M. W., Jager, A., Kriege, M., Tilanus-Linthorst, M. M. A., Collee, M., Wang-Gohrke, S., Pylkas, K., Jukkola-Vuorinen, A., Mononen, K., Grip, M., Hirvikoski, P., Winqvist, R., Mannermaa, A., Kosma, V.-M., Kauppinen, J., Kataja, V., Auvinen, P., Soini, Y., Sironen, R., Bojesen, S. E., Dynnes Orsted, D., Kaur-Knudsen, D., Flyger, H., Nordestgaard, B. G., Holland, H., Chenevix-Trench, G., Manoukian, S., Barile, M., Radice, P., Hankinson, S. E., Hunter, D. J., Tamimi, R., Sangrajrang, S., Brennan, P., McKay, J., Odefrey, F., Gaborieau, V., Devilee, P., Huijts, P. E. A., Tollenaar, R., Seynaeve, C., Dite, G. S., Apicella, C., Hopper, J. L., Hammet, F., Tsimiklis, H., Smith, L. D., Southey, M. C., Humphreys, M. K., Easton, D., Pharoah, P., Sherman, M. E. and Garcia-Closas, M.
    Published:
    2011
    Publication:
    JNCI Journal of the National Cancer Institute
    Volume:
    103, (3)
    Page Range:
    250-263
    doi:
    10.1093/jnci/djq526
    PMID:
    21191117
  • Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers - Walker, Logan C., Fredericksen, Zachary S., Wang, Xianshu, Tarrell, Robert, Pankratz, Vernon S., Lindor, Noralane M., Beesley, Jonathan, Healey, Sue, Chen, Xiaoqing, Stoppa-Lyonnet, Dominique, Tirapo, Carole, Giraud, Sophie, Mazoyer, Sylvie, Muller, Daniele, Fricker, Jean-Pierre, Delnatte, Capucine, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph, Schonbuchner, Ines, Deissler, Helmut, Meindl, Alfons, Hogervorst, Frans B., Verheus, Martijn, Hooning, Maartje J., van den Ouweland, Ans M.W., Nelen, Marcel R., Ausems, Margreet G.E.M., Aalfs, Cora M., van Asperen, Christi J., Devilee, Peter, Gerrits, Monique M., Waisfisz, Quinten, Szabo, Csilla I., Easton, Douglas F., Peock, Susan, Cook, Margaret, Oliver, Clare T., Frost, Debra, Harrington, Patricia, Evans, D. Gareth, Lalloo, Fiona, Eeles, Ros, Izatt, Louise, Chu, Carol, Davidson, Rosemarie, Eccles, Diana, Ong, Kai-Ren, Cook, Jackie, Rebbeck, Tim, Nathanson, Katherine L., Domchek, Susan M., Singer, Christian F, Gschwantler-Kaulich, Daphne, Dressler, Anne-Catharina, Pfeiler, Georg, Godwin, Andrew K., Heikkinen, Tuomas, Nevanlinna, Heli, Agnarsson, Bjarni A., Caligo, Maria Adelaide, Olsson, Hakan, Kristoffersson, Ulf, Liljegren, Annelie, Arver, Brita, Karlsson, Per, Melin, Beatrice, Sinilnikova, Olga M., McGuffog, Lesley, Antoniou, Antonis C., Chenevix-Trench, Georgia, Spurdle, Amanda B. and Couch, Fergus J.
    Published:
    2010
    Publication:
    Breast Cancer Research
    Volume:
    12, (6)
    Page Range:
    R102
    doi:
    10.1186/bcr2785
    PMID:
    21114847
  • Mutation and association analysis of GEN1 in breast cancer susceptibility - Turnbull, Clare, Hines, Sarah, Renwick, Anthony, Hughes, Deborah, Pernet, David, Elliott, Anna, Seal, Sheila, Warren-Perry, Margaret, Gareth Evans, D., Eccles, Diana, Stratton, Michael R. and Rahman, Nazneen
    Published:
    2010
    Publication:
    Breast Cancer Research and Treatment
    Volume:
    124, (1)
    Page Range:
    283-288
    doi:
    10.1007/s10549-010-0949-1
    PMID:
    20512659
  • A novel HER2-positive breast cancer phenotype arising from germline TP53 mutations - Wilson, J.R.F., Bateman, A.C. , Hanson, H., An, Q., Evans , G., Rahman, N., Jones, L.J. and Eccles, D.M.
    Published:
    2010
    Publication:
    Journal of Medical Genetics
    Volume:
    47, (11)
    Page Range:
    771-774
    doi:
    10.1136/jmg.2010.078113
  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population - Antoniou, Antonis C., Wang, Xianshu, Fredericksen, Zachary S., McGuffog, Lesley, Tarrell, Robert, Sinilnikova, Olga M., Healey, Sue, Morrison, Jonathan, Kartsonaki, Christiana, Lesnick, Timothy, Ghoussaini, Maya, Barrowdale, Daniel, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Eccles, Diana, Evans, D. Gareth, Eeles, Ros, Izatt, Louise, Chu, Carol, Douglas, Fiona, Paterson, Joan, Stoppa-Lyonnet, Dominique, Houdayer, Claude, Mazoyer, Sylvie, Giraud, Sophie, Lasset, Christine, Remenieras, Audrey, Caron, Olivier, Hardouin, Agnès, Berthet, Pascaline, Hogervorst, Frans B. L., Rookus, Matti A., Jager, Agnes, van den Ouweland, Ans, Hoogerbrugge, Nicoline, van der Luijt, Rob B., Meijers-Heijboer, Hanne, Gómez García, Encarna B., Devilee, Peter, Vreeswijk, Maaike P. G., Lubinski, Jan, Jakubowska, Anna, Gronwald, Jacek, Huzarski, Tomasz, Byrski, Tomasz, Górski, Bohdan, Cybulski, Cezary, Spurdle, Amanda B., Holland, Helene, Goldgar, David E., John, Esther M., Hopper, John L., Southey, Melissa, Buys, Saundra S., Daly, Mary B., Terry, Mary-Beth, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph, Meindl, Alfons, Preisler-Adams, Sabine, Arnold, Norbert, Niederacher, Dieter, Sutter, Christian, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy, Blum, Joanne L., Piedmonte, Marion, Rodriguez, Gustavo C., Wakeley, Katie, Boggess, John F., Basil, Jack, Blank, Stephanie V., Friedman, Eitan, Kaufman, Bella, Laitman, Yael, Milgrom, Roni, Andrulis, Irene L., Glendon, Gord, Ozcelik, Hilmi, Kirchhoff, Tomas, Vijai, Joseph, Gaudet, Mia M., Altshuler, David, Guiducci, Candace, Loman, Niklas, Harbst, Katja, Rantala, Johanna, Ehrencrona, Hans, Gerdes, Anne-Marie, Thomassen, Mads, Sunde, Lone, Peterlongo, Paolo, Manoukian, Siranoush, Bonanni, Bernardo, Viel, Alessandra, Radice, Paolo, Caldes, Trinidad, de la Hoya, Miguel, Singer, Christian F, Fink-Retter, Anneliese, Greene, Mark H., Mai, Phuong L., Loud, Jennifer T., Guidugli, Lucia, Lindor, Noralane M., Hansen, Thomas V. O., Nielsen, Finn C., Blanco, Ignacio, Lazaro, Conxi, Garber, Judy, Ramus, Susan J., Gayther, Simon A., Phelan, Catherine, Narod, Stephen, Szabo, Csilla I., Benitez, Javier, Osorio, Ana, Nevanlinna, Heli, Heikkinen, Tuomas, Caligo, Maria A., Beattie, Mary S., Hamann, Ute, Godwin, Andrew K., Montagna, Marco, Casella, Cinzia, Neuhausen, Susan L., Karlan, Beth Y., Tung, Nadine, Toland, Amanda E., Weitzel, Jeffrey, Olopade, Olofunmilayo, Simard, Jacques, Soucy, Penny, Rubinstein, Wendy S., Arason, Adalgeir, Rennert, Gad, Martin, Nicholas G., Montgomery, Grant W., Chang-Claude, Jenny, Flesch-Janys, Dieter, Brauch, Hiltrud, Severi, Gianluca, Baglietto, Laura, Cox, Angela, Cross, Simon S, Miron, Penelope, Gerty, Sue M., Tapper, William, Yannoukakos, Drakoulis, Fountzilas, George, Fasching, Peter A., Beckmann, Matthias W., dos Santos Silva, Isabel, Peto, Julian, Lambrechts, Diether, Paridaens, Robert, Rüdiger, Thomas, Försti, Asta, Winqvist, Robert, Pylkäs, Katri, Diasio, Robert B., Lee, Adam M., Eckel-Passow, Jeanette, Vachon, Celine, Blows, Fiona, Driver, Kristy, Dunning, Alison, Pharoah, Paul P. D., Offit, Kenneth, Pankratz, V Shane, Hakonarson, Hakon, Chenevix-Trench, Georgia, Easton, Douglas F. and Couch, Fergus J.
    Published:
    2010
    Publication:
    Nature Genetics
    Volume:
    42, (10)
    Page Range:
    885-892
    doi:
    10.1038/ng.669
  • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 - Goode, Ellen L, Chenevix-Trench, Georgia, Song, Honglin, Ramus, Susan J, Notaridou, Maria, Lawrenson, Kate, Widschwendter, Martin, Vierkant, Robert A, Larson, Melissa C, Kjaer, Susanne K, Birrer, Michael J, Berchuck, Andrew, Schildkraut, Joellen, Tomlinson, Ian, Kiemeney, Lambertus A, Cook, Linda S, Gronwald, Jacek, Garcia-Closas, Montserrat, Gore, Martin E, Campbell, Ian, Whittemore, Alice S, Sutphen, Rebecca, Phelan, Catherine, Anton-Culver, Hoda, Pearce, Celeste Leigh, Lambrechts, Diether, Rossing, Mary Anne, Chang-Claude, Jenny, Moysich, Kirsten B, Goodman, Marc T, Dörk, Thilo, Nevanlinna, Heli, Ness, Roberta B, Rafnar, Thorunn, Hogdall, Claus, Hogdall, Estrid, Fridley, Brooke L, Cunningham, Julie M, Sieh, Weiva, McGuire, Valerie, Godwin, Andrew K, Cramer, Daniel W, Hernandez, Dena, Levine, Douglas, Lu, Karen, Iversen, Edwin S, Palmieri, Rachel T, Houlston, Richard, van Altena, Anne M, Aben, Katja K H, Massuger, Leon F A G, Brooks-Wilson, Angela, Kelemen, Linda E, Le, Nhu D, Jakubowska, Anna, Lubinski, Jan, Medrek, Krzysztof, Stafford, Anne, Easton, Douglas F, Tyrer, Jonathan, Bolton, Kelly L, Harrington, Patricia, Eccles, Diana, Chen, Ann, Molina, Ashley N, Davila, Barbara N, Arango, Hector, Tsai, Ya-Yu, Chen, Zhihua, Risch, Harvey A, McLaughlin, John, Narod, Steven A, Ziogas, Argyrios, Brewster, Wendy, Gentry-Maharaj, Aleksandra, Menon, Usha, Wu, Anna H, Stram, Daniel O, Pike, Malcolm C, Beesley, Jonathan, Webb, Penelope M, Chen, Xiaoqing, Ekici, Arif B, Thiel, Falk C, Beckmann, Matthias W, Yang, Hannah, Wentzensen, Nicolas, Lissowska, Jolanta, Fasching, Peter A, Despierre, Evelyn, Amant, Frederic, Vergote, Ignace, Doherty, Jennifer, Hein, Rebecca, Wang-Gohrke, Shan, Lurie, Galina, Carney, Michael E, Thompson, Pamela J, Runnebaum, Ingo, Hillemanns, Peter, Dürst, Matthias, Antonenkova, Natalia, Bogdanova, Natalia, Leminen, Arto, Butzow, Ralf, Heikkinen, Tuomas, Stefansson, Kari, Sulem, Patrick, Besenbacher, Sören, Sellers, Thomas A, Gayther, Simon A and Pharoah, Paul D P
    Published:
    2010
    Publication:
    Nature Genetics
    Volume:
    42, (10)
    Page Range:
    874-879
    doi:
    10.1038/ng.668
    PMID:
    20852632
  • Survival in women with MMR mutations and ovarian cancer: a multicentre study in Lynch syndrome kindreds - Grindedal, Eli M., Renkonen-Sinisalo, Laura, Vasen, Hans, Evans, Gareth, Sala, Paola, Blanco, Ignacio, Gronwald, Jacek, Apold, Jaran, Eccles, Diana, Sanchez, Ángel Alonso, Sampson, Julian, Jarvinen, Heikki J., Bertario, Lucio, Crawford, Gillan C., Stormorken, Astrid T., Maehle, Lovise and Moller, Pal
    Published:
    2010
    Publication:
    Journal of Medical Genetics
    Volume:
    47, (2)
    Page Range:
    99-102
    doi:
    10.1136/jmg.2009.068130
    PMID:
    19635727
  • Genome-wide association study identifies five new breast cancer susceptibility loci - Turnbull, Clare, Ahmed, Shahana, Morrison, Jonathan, Pernet, David, Renwick, Anthony, Maranian, Mel, Seal, Sheila, Ghoussaini, Maya, Hines, Sarah, Healey, Catherine S, Hughes, Deborah, Warren-Perry, Margaret, Tapper, William, Eccles, Diana, Evans, D Gareth, Hooning, Maartje, Schutte, Mieke, van den Ouweland, Ans, Houlston, Richard, Ross, Gillian, Langford, Cordelia, Pharoah, Paul D P, Stratton, Michael R, Dunning, Alison M, Rahman, Nazneen and Easton, Douglas F
    Published:
    2010
    Publication:
    Nature Genetics
    Volume:
    42, (6)
    Page Range:
    504-507
    doi:
    10.1038/ng.586
    PMID:
    20453838
  • Detection of splicing aberrations caused by BRCA1 and BRCA2 sequence variants encoding missense substitutions: implications for prediction of pathogenicity - Walker, Logan C., Whiley, Phillip J., Couch, Fergus J., Farrugia, Daniel J., Healey, Sue, Eccles, Diana, Lin, Feng, Butler, Samantha A., Goff, Sheila A., Thompson, Bryony A., Lakhani, Sunil R., Da Silva, Leonard M., Tavtigian, Sean V., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B.
    Published:
    2010
    Publication:
    Human Mutation
    Volume:
    31, (6)
    Page Range:
    E1484-E1505
    doi:
    10.1002/humu.21267
  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls - Craddock, Nick, Hurles, Matthew E., Cardin, Niall, Pearson, Richard D., Plagnol, Vincent, Robson, Samuel, Vukcevic, Damjan, Barnes, Chris, Conrad, Donald F., Giannoulatou, Eleni, Holmes, Chris, Marchini, Jonathan L., Stirrups, Kathy, Tobin, Martin D., Wain, Louise V., Yau, Chris, Aerts, Jan, Ahmad, Tariq, Daniel Andrews, T., Arbury, Hazel, Attwood, Anthony, Auton, Adam, Ball, Stephen G., Balmforth, Anthony J., Barrett, Jeffrey C., Barroso, Inês, Barton, Anne, Bennett, Amanda J., Bhaskar, Sanjeev, Blaszczyk, Katarzyna, Bowes, John, Brand, Oliver J., Braund, Peter S., Bredin, Francesca, Breen, Gerome, Brown, Morris J., Bruce, Ian N., Bull, Jaswinder, Burren, Oliver S., Burton, John, Byrnes, Jake, Caesar, Sian, Clee, Chris M., Coffey, Alison J., Connell, John M.C., Cooper, Jason D., Dominiczak, Anna F., Downes, Kate, Drummond, Hazel E., Dudakia, Darshna, Dunham, Andrew, Ebbs, Bernadette, Eccles, Diana, Edkins, Sarah, Edwards, Cathryn, Elliot, Anna, Emery, Paul, Evans, David M., Evans, Gareth, Eyre, Steve, Farmer, Anne, Nicol Ferrier, I., Feuk, Lars, Fitzgerald, Tomas, Flynn, Edward, Forbes, Alistair, Forty, Liz, Franklyn, Jayne A., Freathy, Rachel M., Gibbs, Polly, Gilbert, Paul, Gokumen, Omer, Gordon-Smith, Katherine, Gray, Emma, Green, Elaine, Groves, Chris J., Grozeva, Detelina, Gwilliam, Rhian, Hall, Anita, Hammond, Naomi, Hardy, Matt, Harrison, Pile, Hassanali, Neelam, Hebaishi, Husam, Hines, Sarah, Hinks, Anne, Hitman, Graham A., Hocking, Lynne, Howard, Eleanor, Howard, Philip, Howson, Joanna M.M., Hughes, Debbie, Hunt, Sarah, Isaacs, John D., Jain, Mahim, Jewell, Derek P., Johnson, Toby, Jolley, Jennifer D., Jones, Ian R., Jones, Lisa A., Kirov, George, Langford, Cordelia F., Lango-Allen, Hana, Mark Lathrop, G., Lee, James, Lee, Kate L., Lees, Charlie, Lewis, Kevin, Lindgren, Cecilia M., Maisuria-Armer, Meeta, Maller, Julian, Mansfield, John, Martin, Paul, Massey, Dunecan C.O., McArdle, Wendy L., McGuffin, Peter, McLay, Kirsten E., Mentzer, Alex, Mimmack, Michael L., Morgan, Ann E., Morris, Andrew P., Mowat, Craig, Myers, Simon, Newman, William, Nimmo, Elaine R., O’Donovan, Michael C., Onipinla, Abiodun, Onyiah, Ifejinelo, Ovington, Nigel R., Owen, Michael J., Palin, Kimmo, Parnell, Kirstie, Pernet, David, Perry, John R. B., Phillips, Anne, Pinto, Dalila, Prescott, Natalie J., Prokopenko, Inga, Quail, Michael A., Rafelt, Suzanne, Rayner, Nigel W., Redon, Richard, Reid, David M., Renwick, Anthony, Ring, Susan M., Robertson, Neil, Russell, Ellie, St Clair, David, Sambrook, Jennifer G., Sanderson, Jeremy D., Schuilenburg, Helen, Scott, Carol E., Scott, Richard, Seal, Sheila, Shaw-Hawkins, Sue, Shields, Beverley M., Simmonds, Matthew J., Smyth, Debbie J., Somaskantharajah, Elilan, Spanova, Katarina, Steer, Sophia, Stephens, Jonathan, Stevens, Helen E., Stone, Millicent A., Su, Zhan, Symmons, Deborah P.M., Thompson, John R., Thomson, Wendy, Travers, Mary E., Turnbull, Clare, Valsesia, Armand, Walker, Mark, Walker, Neil M., Wallace, Chris, Warren-Perry, Margaret, Watkins, Nicholas A., Webster, John, Weedon, Michael N., Wilson, Anthony G., Woodburn, Matthew, Wordsworth, B. Paul, Young, Allan H., Zeggini, Eleftheria, Carter, Nigel P., Frayling, Timothy M., Lee, Charles, McVean, Gil, Munroe, Patricia B., Palotie, Aarno, Sawcer, Stephen J., Scherer, Stephen W., Strachan, David P., Tyler-Smith, Chris, Brown, Matthew A., Burton, Paul R., Caulfield, Mark J., Compston, Alastair, Farrall, Martin, Gough, Stephen C.L., Hall, Alistair S., Hattersley, Andrew T., Hill, Adrian V.S., Mathew, Christopher G., Pembrey, Marcus, Satsangi, Jack, Stratton, Michael R., Worthington, Jane, Deloukas, Panos, Duncanson, Audrey, Kwiatkowski, Dominic P., McCarthy, Mark I., Ouwehand, Willem H., Parkes, Miles, Rahman, Nazneen, Todd, John A., Samani, Nilesh J. and Donnelly, Peter
    Published:
    2010
    Publication:
    Nature
    Volume:
    464, (7289)
    Page Range:
    713-720
    doi:
    10.1038/nature08979
  • Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study - Mitra, Anita V., Bancroft, Elizabeth K., Barbachano, Yolanda, Page, Elizabeth C., Foster, C.S., Jameson, C., Mitchell, G., Lindeman, G.J., Stapleton, A., Suthers, G., Evans, D.G., Cruger, D., Blanco, I., Mercer, C., Kirk, J., Maehle, L., Hodgson, S., Walker, L., Izatt, L., Douglas, F., Tucker, K., Dorkins, H., Clowes, V., Male, A., Donaldson, A., Brewer, C., Doherty, R., Bulman, B., Osther, P.J., Salinas, M., Eccles, D., Axcrona, K., Jobson, I., Newcombe, B., Cybulski, C., Rubinstein, W.S., Buys, S., Townshend, S., Friedman, E., Domchek, S., Ramon y Cajal, T., Spigelman, A., Teo, S.H., Nicolai, N., Aaronson, N., Ardern-Jones, A., Bangma, C., Dearnaley, D., Eyfjord, J., Falconer, A., Grönberg, H., Hamdy, F., Johannsson, O., Khoo, V., Kote-Jarai, Z., Lilja, H., Lubinski, J., Melia, J., Moynihan, C., Peock, S., Rennert, G., Schröder, F., Sibley, P., Suri, M., Wilson, P., Bignon, Y.J., Strom, S., Tischkowitz, M., Liljegren, A., Ilencikova, D., Abele, A., Kyriacou, K., van Asperen, C., Kiemeney, L., Easton, D.F. and Eeles, Rosalind A.
    Published:
    2010
    Publication:
    BJU International
    Volume:
    107, (1)
    Page Range:
    28-39
    doi:
    10.1111/j.1464-410X.2010.09648.x
    PMID:
    20840664
  • The influence of common polymorphisms on breast cancer - Eccles, Diana and Tapper, William
    Published:
    2010
    Publication:
    Cancer Treatment and Research
    Volume:
    155
    Page Range:
    15-32
    doi:
    10.1007/978-1-4419-6033-7_2
    PMID:
    20517686
  • Development of genetic testing for breast, ovarian and colorectal cancer predisposition: a step closer to targeted cancer prevention - Eccles, Diana
    Published:
    2010
    Publication:
    Current Drug Targets
    Volume:
    12, (13)
    Page Range:
    1974-1982
    doi:
    10.2174/138945011798184209
    PMID:
    21158705
  • Identification of a de novo BRCA1 mutation in a woman with early onset bilateral breast cancer. - Edwards, Emma, Yearwood, Catharina, Sillibourne, Julie, Baralle, Diana and Eccles, Diana
    Published:
    2009
    Publication:
    Familial Cancer
    Volume:
    8, (4)
    Page Range:
    479-482
    doi:
    10.1007/s10689-009-9270-8
  • Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers - Antoniou, A.C., Sinilnikova, O.M., McGuffog, L., Healey, S., Nevanlinna, H., Heikkinen, T., Simard, J., Spurdle, A.B., Beesley, J., Chen, X., Neuhausen, S.L., Ding, Y.C., Couch, F.J., Wang, X., Fredericksen, Z., Peterlongo, P., Peissel, B., Bonanni, B., Viel, A., Bernard, L., Radice, P., Szabo, C.I., Foretova, L., Zikan, M., Claes, K., Greene, M.H., Mai, P.L., Rennert, G., Lejbkowicz, F., Andrulis, I.L., Ozcelik, H., Glendon, G., Gerdes, A.M., Thomassen, M., Sunde, L., Caligo, M.A., Laitman, Y., Kontorovich, T., Cohen, S., Kaufman, B., Dagan, E., Baruch, R.G., Friedman, E., Harbst, K., Barbany-Bustinza, G., Rantala, J., Ehrencrona, H., Karlsson, P., Domchek, S.M., Nathanson, K.L., Osorio, A., Blanco, I., Lasa, A., Benitez, J., Hammann, U., Hogervorst, F.B., Rookus, M.A., Collee, J.M., Devilee, P., Ligtenberg, M.J., van der Luijt, R.B., Aalfs, C.M., Waisfisz, Q., Wijnen, J., van Roozendaal, C.E., Peock, S., Cook, M., Frost, D., Oliver, C., Platte, R., Evans, D.G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Chu, C., Eccles, D., Cole, T., Hodgson, S., Godwin, A.K., Stoppa-Lyonnet, D., Buecher, B., Leone, M., Bressac-de Paillerets, B., Remenieras, A., Caron, O., Lenoir, G.M., Sevenet, N., Longy, M., Ferrer, S.F., Prieur, F., Goldgar, D., Miron, A., John, E.M., Buys, S.S., Daly, M.B., Hopper, J.L., Terry, M.B., Yassin, Y., Singer, C., Gschwantler-Kaulich, D., Staudigl, C., Hansen, T.O., Barkardottir, R.B., Kirchhoff, T., Pal, P., Kosarin, K., Offit, K., Piedmonte, M., Rodriguez, G.C., Wakeley, K., Boggess, J.F., Basil, J., Schwartz, P.E., Blank, S.V., Toland, A.E., Montagna, M., Casella, C., Imyanitov, E.N., Allavena, A., Schmutzler, R.K., Versmold, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Niederacher, D., Deissler, H., Fiebig, B., Suttner, C., Schonbuchner, I., Gadzicki, D., Caldes, T., de la Hoya, M., Pooley, J.A., Easton, D.F. and Chenevix-Trench, G.
    Published:
    2009
    Publication:
    Human Molecular Genetics
    Volume:
    18, (22)
    Page Range:
    4442-4456
    doi:
    10.1093/hmg/ddp372
  • No evidence that GATA3 rs570613 SNP modifies breast cancer risk - Johnatty, Sharon E., Couch, Fergus J., Fredericksen, Zachary, Tarrell, Robert, Spurdle, Amanda B., Beesley, Jonathan, Chen, Xiaoqing, Gschwantler-Kaulich, Daphne, Singer, Christian F., Fuerhauser, Christine, Fink-Retter, Anneliese, Domchek, Susan M., Nathanson, Katherine L., Pankratz, Vernon S., Lindor, Noralane M., Godwin, Andrew K., Caligo, Maria A., Hopper, John, Southey, Melissa C., Giles, Graham G., Justenhoven, Christina, Brauch, Hiltrud, Hamann, Ute, Ko, Yon-Dschun, Heikkinen, Tuomas, Aaltonen, Kirsimari, Aittomaki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli, Hall, Per, Czene, Kamila, Liu, Jianjun, Peock, Susan, Cook, Margaret, Platte, Radka, Evans, D. Gareth, Lalloo, Fiona, Eeles, Rosalind, Pichert, Gabriella, Eccles, Diana, Davidson, Rosemarie, Cole, Trevor, Cook, Jackie, Douglas, Fiona, Chu, Carol, Hodgson, Shirley, Paterson, Joan, Hogervorst, Frans B. L, Rookus, Matti A., Seynaeve, Caroline, Wijnen, Juul, Vreeswijk, Maaike, Ligtenberg, Marjolijn, van der Luijt, Rob B., van Os, Theo A. M, Gille, Hans J. P, Blok, Marinus J., Issacs, Claudine, Humphreys, Manjeet K., McGuffog, Lesley, Healey, Sue, Sinilnikova, Olga, Antoniou, Antonis C., Easton, Douglas F. and Chenevix-Trench, Georgia
    Published:
    2009
    Publication:
    Breast Cancer Research and Treatment
    Volume:
    117, (2)
    Page Range:
    371-379
    doi:
    10.1007/s10549-008-0257-1
  • Newly discovered breast cancer susceptibility loci in 3p24 and 17q23.2 - Ahmed, S., Ghoussaini, M., Healey, C.S., Humphreys, M.K., Platte, R., Morrison, J., Maranian, M., Pooley, K.A., Luben, R., Eccles, D., Evans, D.G., Fletcher, O., Johnson, N., dos Santos Silva, I., Peto, J., Stratton, M.R., Rahman, N., Jacobs, K., Prentice, R., Anderson, G.L., Rajkovic, A., Curb, J.D., Ziegler, R.G., Berg, C.D., Buys, S.S., McCarthy, C.A., Feigelson, H.S., Calle, E.E., Thun, M.J., Diver, W.R., Bojesen, S., Nordestgaard, B.G., Flyger, H., Dork, T., Schurmann, P., Hillemanns, P., Karstens, J.H., Bogdanova, N.V., Antonenkova, N.N., Zalutsky, I.V., Bermisheva, M., Fedorova, S., Khusnutdinova, E., Kang, D., Yoo, K.Y., Noh, D.Y., Ahn, S.H., Devilee, P., van Asperen, C.J., Tollenaar, R.S., Seynaeve, C., Garcia-Closas, M., Lissowska, J., Brinton, L., Peplonska, B., Nevanlinna, H., Heikkinen, T., Aittomaki, K., Blomqvist, C., Hopper, J.L., Southey, M.C., Smith, L., Spurdle, A.B., Schmidt, M.K., Broeks, A., van Hien, R.R., Cornelissen, S., Milne, R.L., Ribas, G., Gonzalez-Neira, A., Benitez, J., Schmutzler, R.K., Burwinkel, B., Bartram, C.R., Meindl, A., Brauch, H., Justenhoven, C., Hammann, U., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V.M., Kataja, V., Olson, J.E., Wang, X., Fredericksen, Z., Giles, G.G., Severi, G., Baglietto, L., English, D.R., Hankinson, S.E., Cox, D.G., Kraft, P., Vatten, L.J., Hveem, K., Kumle, M., Sigurdson, A., Doody, M., Bhatti, P., Alexander, B.H., Hooning, N.J., van den Ouweland, A.M., Oldenburg, R.A., Schutte, M., Hall, P., Czene, K., Liu, J., Li, Y., Cox, A., Elliott, G., Brock, I., Reed, M.W., Shen, C.Y., Yu, J.C., Hsu, G.C., Chen, S.T., Anton-Culver, H., Ziogas, A., Andrulis, I.L., Knight, J.A., Beesley, J., Goode, E.L., Couch, F., Chenevix-Trench, G., Hoover, R.N., Ponder, B.A., Hunter, D.J., Pharaoah, P.D., Dunning, A.M., Chanock, S.J. and Easton, D.F.
    Published:
    2009
    Publication:
    Nature Genetics
    Volume:
    41, (5)
    Page Range:
    585-590
    doi:
    10.1038/ng.354
    PMID:
    19330027
  • Risk reducing mastectomy: outcomes in 10 European centres - Evans, D.G.R., Baildam, A.D., Anderson, E., Brain, A., Shenton, A., Vasen, H.F.A., Eccles, D., Lucassen, A., Pichert, G., Hamed, H., Moller, P., Maehle, L., Morrison, P.J., Stoppart-Lyonnet, D., Gregory, H., Smyth, E., Niederacher, D., Nestle-Krämling, C., Campbell, J., Hopwood, P., Lalloo, F. and Howell, A.
    Published:
    2009
    Publication:
    Journal of Medical Genetics
    Volume:
    46, (4)
    Page Range:
    254-258
    doi:
    10.1136/jmg.2008.062232
  • The influence of genetic variation in thirty selected genes on the clinical characteristics of early onset breast cancer - Tapper, William, Hammond, Victoria, Gerty, Sue, Ennis, Sarah, Simmonds, Peter, Collins, Andrew and Eccles, Diana
    Published:
    2008
    Publication:
    Breast Cancer Research
    Volume:
    10, (6)
    Page Range:
    R108
    doi:
    10.1186/bcr2213
    PMID:
    19094228
  • Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch Syndrome - Burn, John, Bishop, D.Timothy, Mecklin, Jukka-Pekka, Macrae, Finlay, Möslein, Gabriela, Olschwang, Sylviane, Bisgaard, Marie-Luise, Ramesar, Raj, Eccles, Diana, Maher, Eamonn, Bertario, Lucio, Jarvinen, Heikki J., Lindblom, Annika, Evans, D.Gareth, Lubinski, Jan, Morrison, Patrick J., Ho, Judy W.C., Vasen, Hans F.A., Side, Lucy, Thomas, Huw J.W., Scott, Rodney J., Dunlop, Malcolm, Barker, Gail, Elliott, Faye, Jass, Jeremy R., Fodde, Ricardo, Lynch, Henry T. and Mathers, John C.
    Published:
    2008
    Publication:
    New England Journal of Medicine
    Volume:
    359, (24)
    Page Range:
    2567-2578
    doi:
    10.1056/NEJMoa0801297
    PMID:
    19073976
  • Breast cancer: genetics - Eccles, D.
    Published:
    2008
    Publication:
    Menopause International
    Volume:
    14, (4)
    Page Range:
    183-183
    doi:
    10.1258/mi.2008.008037
  • Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance - Hofstra, Robert M.W., Spurdle, Amanda B., Eccles, Diana M., Foulkes, William D., de Wind, Niels, Hoogerbrugge, Nicoline and Hogervorst, Frans B.L.
    Published:
    2008
    Publication:
    Human Mutation
    Volume:
    29, (11)
    Page Range:
    1292-1303
    doi:
    10.1002/humu.20894
    PMID:
    1895144
  • Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results - Plon, S.E., Eccles, D.M., Easton, D., Foulkes, W.D., Genuardi, M., Greenblatt, M.S., Hogervorst, F.B., Hoogerbrugge, N., Spurdle, A.B. and Tavtigian, S.V.
    Published:
    2008
    Publication:
    Human Mutation
    Volume:
    29, (11)
    Page Range:
    1282-1291
    doi:
    10.1002/humu.20880
  • Prevalence of adenomas and hyperplastic polyps in mismatch repair mutation carriers among CAPP2 participants: report by the colorectal adenoma/carcinoma prevention programme 2 - Liljegren, A., Barker, G., Elliott, F., Bertario, L., Bisgaard, M.L., Eccles, D., Evans, G., Macrae, F., Maher, E., Lindblom, A., Rotstein, S., Nilsson, B., Mecklin, J.P., Moslein, G., Jass, J., Fodde, R., Mathers, J., Burn, J. and Bishop, D.T.
    Published:
    2008
    Publication:
    Journal of Clinical Oncology
    Volume:
    26, (20)
    Page Range:
    3434-3439
    doi:
    10.1200/JCO.2007.13.2795
  • Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics - Antoniou, A.C., Hardy, R., Walker, L., Evans, D.G., Shenton, A., Eeles, R., Shanley, S., Pichert, G., Izatt, L., Rose, S., Douglas, F., Eccles, D., Morrison, P.J., Scott, J., Zimmern, R.L., Easton, D.F. and Pharoah, P.D.P.
    Published:
    2008
    Publication:
    Journal of Medical Genetics
    Volume:
    45, (7)
    Page Range:
    425-431
    doi:
    10.1136/jmg.2007.056556
  • Prospective study of outcome in sporadic versus hereditary breast cancer: pros and cons of running a cohort study - Gerty, S.M., Simmonds, P.D., Durcan, L. and Eccles, D.M.
    Published:
    2008
    Publication:
    Breast Cancer Research
    Volume:
    10, (Suppl 2)
    Page Range:
    S36-S37
    doi:
    10.1186/bcr1955
  • Identification of personal risk of breast cancer: genetics - Eccles, Diana M.
    Published:
    2008
    Publication:
    Breast Cancer Research
    Volume:
    10, (Suppl 4)
    Page Range:
    p.S12
    doi:
    10.1186/bcr2172
  • Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers - Antoniou, A.C., Spurdle, A.B., Sinilnikova, O.M., Healey, S., Pooley, K.A., Schmutzler, R.K., Versmold, B., Engel, C., Meindl, A., Arnold, N., Hofmann, W., Sutter, C., Niederacher, D., Deissler, H., Caldes, T., Kampjarvi, K., Nevanlinna, H., Simard, J., Beesley, J., Chen, X.Q., Neuhausen, S.L., Rebbeck, T.R., Wagner, T., Lynch, H.T., Isaacs, C., Weitzel, J., Ganz, P.A., Daly, M.B., Tomlinson, G., Olopade, O.I., Bium, J.L., Couch, F. J., Peterlongo, P., Manoukian, S., Barile, M., Radice, P., Szabo, C.I., Pereira, L.H.M., Greene, M.H., Rennert, G., Leibkowicz, F., Barnett-Griness, O., Andrulis, I.L., Ozcelik, H., Gerdes, A.M., Caligo, M.A., Laitman, Y., Kaufman, B., Milgrom, R., Friedman, E., Domchek, S.M., Nathanson, K.L., Osorio, A., Llort, G., Milne, R.L., Benitez, J., Hamann, U., Hogervorst, F.B.L., Manders, P., Ligtenberg, M.J.L., Van den, A.M.W., Peock, S., Cook, M., Platte, R., Evans, D.G., Eeles, R., Pichert, G., Chu, C., Eccles, D., Davidson, R., Douglas, F., Godwin, A.K., Barjhoux, L., Mazoyer, S., Sobol, H., Bourdon, V., Eisinger, F., Chompret, A., Capoulade, C., Paillerets, B.B.D., Lenoir, G.M., Gauthier-Villars, M., Houdayer, C., Stoppa-Lyonnet, D. and Easton, D.F.
    Published:
    2008
    Publication:
    American Journal of Human Genetics
    Volume:
    82, (4)
    Page Range:
    937-948
    doi:
    10.1016/j.ajhg.2008.02.008
  • Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3 - Dallosso, A.R., Dolwani, S., Jones, N., Jones, S., Colley, J., Maynard, J., Idziaszczyk, S., Humphreys, V., Arnold, J., Donaldson, A., Eccles, D., Ellis, A., Evans, D.G., Frayling, I.M., Hes, F.J., Houlston, R.S., Meyer, E.R., Nielsen, M., Parry, S., Tyler, E., Moskvina, V., Cheadle, J.P. and Sampson, J.R.
    Published:
    2008
    Publication:
    Gut: an International Journal of Gastroenterology and Hepatology
    Volume:
    57, (9)
    Page Range:
    1252-1255
    doi:
    10.1136/gut.2007.145748
  • The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions - Antoniou, A.C., Cunningham, A.P., Peto, J., Evans, D.G., Lalloo, F., Narod, S.A., Risch, H.A., Eyfjord, J.E., Hopper, J.L., Southey, M.C., Olsson, H., Johannsson, O., Borg, A., Pasini, B., Radice, P., Manoukian, S., Eccles, D.M., Tang, N., Olah, E., Anton-Culver, H., Warner, E., Lubinski, J., Gronwald, J., Gorski, B., Tryggvadottir, L., Syrjakoski, K., Kallioniemi, O.P., Eerola, H., Nevanlinna, H., Pharoah, P.D. and Easton, D.F.
    Published:
    2008
    Publication:
    British Journal of Cancer
    Volume:
    98, (8)
    Page Range:
    1457-1466
    doi:
    10.1038/sj.bjc.6604305
  • Predictive genetic testing for BRCA1/2 in a UK clinical cohort: three year follow up - Foster, C., Watson, M., Eeles, R., Eccles, D., Ashley, S., Davidson, R., Mackay, J., Morrison, P.J., Hopwood, P. and Evans, D.G.R.
    Published:
    2007
    Publication:
    Psycho-Oncology
    Volume:
    16, (S2)
    Page Range:
    S20-S20
    doi:
    10.1002/pon.1266
  • Prospective study of outcomes in Sporadic versus hereditary breast cancer (POSH): study protocol - Eccles, Diana, Gerty, Sue, Simmonds, Peter, Hammond, Victoria, Ennis, Sarah and Altman, Douglas G.
    Published:
    2007
    Publication:
    BMC Cancer
    Volume:
    7
    Page Range:
    [6pp]
    doi:
    10.1186/1471-2407-7-160
  • Genome-wide association study identifies novel breast cancer susceptibility loci - Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D.P., Thompson, Deborah, Ballinger, Dennis G., Struewing, Jeffery P., Morrison, Jonathan, Field, Helen, Luben, Robert, Wareham, Nicholas, Ahmed, Shahana, Healey, Catherine S., Bowman, Richard, Meyer, Kerstin B., Haiman, Christopher A., Kolonel, Laurence K., Henderson, Brian E., Le Marchand, Loic, Brennan, Paul, Sangrajrang, Suleeporn, Gaborieau, Valerie, Odefrey, Fabrice, Shen, Chen-Yang, Wu, Pei-Ei, Wang, Hui-Chun, Eccles, Diana, Evans, D. Gareth, Peto, Julian, Fletcher, Olivia, Johnson, Nichola, Seal, Sheila, Stratton, Michael R., Rahman, Nazneen, Chenevix-Trench, Georgia, Bojesen, Stig E., Nordestgaard, Børge G., Axelsson, Christen K., Garcia-Closas, Montserrat, Brinton, Louise, Chanock, Stephen, Lissowska, Jolanta, Peplonska, Beata, Nevanlinna, Heli, Fagerholm, Rainer, Eerola, Hannaleena, Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Ahn, Sei-Hyun, Hunter, David J., Hankinson, Susan E., Cox, David G., Hal, Per, Wedren, Sara, Liu, Jianjun, Low, Yen-Ling, Bogdanova, Natalia, Schürmann, Peter, Dörk, Thilo, Tollenaar, Rob A.E.M., Jacobi, Catharina E., Devilee, Peter, Klijn, Jan G.M., Sigurdson, Alice J., Doody, Michele M., Alexander, Bruce H., Zhang, Jinghui, Cox, Angela, Brock, Ian W., MacPherson, Gordon, Reed, Malcolm W. R., Couch, Fergus J., Goode, Ellen L., Olson, Janet E., Meijers-Heijboer, Hanne, van den Ouweland, Ans, Uitterlinden, André, Rivadeneira, Fernando, Milne, Roger L., Ribas, Gloria, Gonzalez-Neira, Anna, Benitez, Javier, Hopper, John L., McCredie, Margaret, Southey, Melissa, Giles, Graham G., Schroen, Chris, Justenhoven, Christina, Brauch, Hiltrud, Hamann, Ute, Ko, Yon-Dschun, Spurdle, Amanda B., Beesley, Jonathan, Chen, Xiaoqing, Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Hartikainen, Jaana, Day, Nicholas E., Cox, David R. and Ponder, Bruce A. J.
    Published:
    2007
    Publication:
    Nature
    Volume:
    447, (7148)
    Page Range:
    1087-1093
    doi:
    10.1038/nature05887
  • Predictive genetic testing for BRCA1/2 in a UK clinical cohort: three-year follow-up - Foster, C., Watson, M., Eeles, R., Eccles, D., Ashley, S., Davidson, R., Mackay, J., Morrison, P.J., Hopwood, P. and Evans, D.G.R.
    Published:
    2007
    Publication:
    British Journal of Cancer
    Volume:
    96, (5)
    Page Range:
    718-724
    doi:
    10.1038/sj.bjc.6603610
  • PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene - Rahman, Nazneen, Seal, Sheila, Thompson, Deborah, Kelly, Patrick, Renwick, Anthony, Elliott, Anna, Reid, Sarah, Spanova, Katarina, Barfoot, Rita, Chagtai, Tasnim, Jayatilake, Hiran, McGuffog, Lesley, Hanks, Sandra, Evans, D. Gareth, Eccles, Diana, Easton, Douglas F. and Stratton, Michael R.
    Published:
    2007
    Publication:
    Nature Genetics
    Volume:
    39, (2)
    Page Range:
    165-167
    doi:
    10.1038/ng1959
  • Inherited mutations in BRCA1 are much more frequent than in BRCA2 amongst young breast cancer cases - Hammond, V.N., Gerty, S.M., Sillibourne, J., Ward, D., Mattocks, C., Simmonds, P., Graham, N., Armstrong, M. and Eccles, D.M.
    Published:
    2007
    Publication:
    Journal of Medical Genetics
    Volume:
    44
    Page Range:
    pp.S132
  • PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene - Rahman, Nazneen, Seal, Sheila, Thompson, Deborah, Kelly, Patrick, Renwick, Anthony, Elliott, Anna, Reid, Sarah, Spanova, Katarina, Barfoot, Rita, Chagtai, Tasnim, Jayatilake, Hiran, McGuffog, Lesley, Hanks, Sandra, Evans, D. Gareth, Eccles, Diana, Easton, Douglas F. and Stratton, Michael R.
    Published:
    2007
    Publication:
    Nature Genetics
    Volume:
    39, (2)
    Page Range:
    165-167
    doi:
    10.1038/ng1959
  • Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom - Shanley, Susan, McReynolds, Kate, Rdern-Jones, Audrey, Ahern, Roger, Fernando, Indrajit, Yarnold, John, Evans, Gareth, Eccles, Diana, Hodgson, Shirley, Ashley, Sue, Ashcroft, Linda, Tutt, Andrew, Bancroft, Elizabeth, Short, Susan, Gui, Gerald, Barr, Lester, Baildam, Andrew, Howell, Anthony, Royle, Gavin, Pierce, Lori, Easton, Douglas and Eeles, Rosalind
    Published:
    2006
    Publication:
    Clinical Cancer Research
    Volume:
    12, (23)
    Page Range:
    7025-7032
  • Acute chemotherapy-related toxicity is not increased in BRCA1 and BRCA2 mutation carriers treated for breast cancer in the United Kingdom - Shanley, Susan, McReynolds, Kate, Rdern-Jones, Audrey, Ahern, Roger, Fernando, Indrajit, Yarnold, John, Evans, Gareth, Eccles, Diana, Hodgson, Shirley, Ashley, Sue, Ashcroft, Linda, Tutt, Andrew, Bancroft, Elizabeth, Short, Susan, Smith, Ian, Gui, Gerald, Barr, Lester, Baildam, Andrew, Howell, Anthony, Royle, Gavin, Pierce, Lori, Easton, Douglas and Eeles, Rosalind
    Published:
    2006
    Publication:
    Clinical Cancer Research
    Volume:
    12, (23)
    Page Range:
    7033-7038
  • High-grade ER-negative tumour breast cancers are characteristic of both very young onset cases and patients with hereditary breast cancer - Eccles, D., Gerty, S. and Simmonds, P.
    Published:
    2006
    Publication:
    Breast Cancer Research
    Volume:
    8, (Suppl 2)
    Page Range:
    S13-S14
    doi:
    10.1186/bcr1582
  • Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles - Seal, Sheila, Thompson, Deborah, Renwick, Anthony, Elliott, Anna, Kelly, Patrick, Barfoot, Rita, Chagtai, Tasnim, Jayatilake, Hiran, Ahmed, Munaza, Spanova, Katarina, North, Bernard, McGuffog, Lesley, Evans, D. Gareth, Eccles, Diana, Easton, Douglas F., Stratton, Michael R. and Rahman, Nazneen
    Published:
    2006
    Publication:
    Nature Genetics
    Volume:
    38, (11)
    Page Range:
    1239-1241
    doi:
    10.1038/ng1902
  • ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles - Renwick, Anthony, Thompson, Deborah, Seal, Sheila, Kelly, Patrick, Chagtai, Tasnim, Ahmed, Munaza, North, Bernard, Jayatilake, Hiran, Barfoot, Rita, Spanova, Katarina, McGuffog, Lesley, Evans, D. Gareth, Eccles, Diana, Easton, Douglas F., Stratton, Michael R. and Rahman, Nazneen
    Published:
    2006
    Publication:
    Nature Genetics
    Volume:
    38, (8)
    Page Range:
    873-875
    doi:
    10.1038/ng1837
  • Optimal selection of individuals for BRCA mutation testing - Gareth, D., Evans, R., Lalloo, F. and Eccles, D.
    Published:
    2006
    Publication:
    Journal of Clinical Oncology
    Volume:
    24, (20)
    Page Range:
    3311
    doi:
    10.1200/JCO.2006.06.6134
  • Accurate prediction of BRCA1 and BRCA2 heterozygous genotype using expression profiling after induced DNA damage - Kote-Jarai, Zsofia, Matthews, Lucy, Osorio, Ana, Shanley, Susan, Giddings, Ian, Moreews, Francois, Locke, Imogen, Evans, D. Gareth, Eccles, Diana, Williams, Richard D., Girolami, Mark, Campbell, Colin and Eeles, Ros
    Published:
    2006
    Publication:
    Clinical Cancer Research
    Volume:
    12, (13)
    Page Range:
    3896-3901
  • A genome wide linkage search for breast cancer susceptibility genes - Smith, Paula, McGuffog, Lesley, Easton, Douglas F., Mann, Graham J., Pupo, Gulietta M., Newman, Beth, Chenevix-Trench, Georgia, Szabo, Csilla, Southey, Melissa, Renard, Hélène, Odefrey, Fabrice, Lynch, Henry, Stoppa-Lyonnet, Dominique, Couch, Fergus, Hopper, John L., Giles, Graham G., McCredie, Margaret R.E., Buys, Saundra, Andrulis, Irene, Senie, Ruby, Goldgar, David E., Oldenburg, Rogier, Kroeze-Jansema, Karin, Kraan, Jaennelle, Meijers-Heijboer, Hanne, Klijn, Jan G.M., van Asperen, Christi, van Leeuwen, Inge, Vasen, Hans F.A., Cornelisse, Cees J., Devilee, Peter, Baskcomb, Linda, Seal, Sheila, Barfoot, Rita, Mangion, Jon, Hall, Anita, Edkins, Sarah, Rapley, Elizabeth, Wooster, Richard, Chang-Claude, Jenny, Eccles, Diana, Evans, D. Gareth, Futreal, P. Andrew, Nathanson, Katherine L., Weber, Barbara L., Rahman, Nazneen and Stratton, Michael R.
    Published:
    2006
    Publication:
    Genes, Chromosomes and Cancer
    Volume:
    45, (7)
    Page Range:
    646-655
    doi:
    10.1002/gcc.20330
  • Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers - Copson, Ellen R., White, Helen E., Blaydes, Jeremy P., Robinson, David O., Johnson, Peter W. and Eccles, Diana M.
    Published:
    2006
    Publication:
    BMC Cancer
    Volume:
    6, (80)
    doi:
    10.1186/1471-2407-6-80
  • Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers - Mitchell, Gillian, Antoniou, Antonis C., Warren, Ruth, Peock, Susan, Brown, Judith, Davies, Russell, Mattison, Jenny, Cook, Margaret, Warsi, Iqbal, Evans, D. Gareth, Eccles, Diana, Douglas, Fiona, Paterson, Joan, Hodgson, Shirley, Izatt, Louise, Cole, Trevor, Burgess, Lucy, Eeles, Ros and Easton, Douglas F.
    Published:
    2006
    Publication:
    Cancer Research
    Volume:
    66, (3)
    Page Range:
    1866-1872
  • Clinicopathological characteristics of young onset breast cancer: initial results from a prospective cohort study - Simmonds, P.D., Eccles, D.M. and Gerty, S.
    Published:
    2005
    Publication:
    Breast Cancer Research and Treatment
    Volume:
    94, (Supplement 1)
    Page Range:
    p.S22
    doi:
    10.1007/s10549-005-1234-6
  • A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer - Thompson, Ella, Dragovic, Rebecca L., Stephenson, Sally-Anne, Eccles, Diana M., Campbell, Ian G. and Dobrovic, Alexander
    Published:
    2005
    Publication:
    BMC Cancer
    Volume:
    5, (1)
    doi:
    10.1186/1471-2407-5-43
  • Mutation scanning by meltMADGE: validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population - Alharbi, Khalid K., Aldahmesh, Mohammed A., Spanakis, Emmanuel, Haddad, Lema, Whittall, Roslyn A., Chen, Xiao-he, Rassoulian, Hamid, Smith, Matt J., Sillibourne, Julie, Ball, Nicola J., Graham, Nikki J., Briggs, Patricia J., Simpson, Iain A., Phillips, David I.W., Lawlor, Deborah A., Ye, Shu, Humphries, Stephen E., Cooper, Cyrus, Smith, George Davey, Ebrahim, Shah, Eccles, Diana M. and Day, Ian N.M.
    Published:
    2005
    Publication:
    Genome Research
    Volume:
    15, (7)
    Page Range:
    967-977
    doi:
    10.1101/gr.3313405
  • Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies - Antoniou, A.C., Pharoah, P.D., Narod, S., Risch, H.A., Eyfjord, J.E., Hopper, J.L., Olsson, H., Johannsson, O., Borg, A., Pasini, B., Radice, P., Manoukian, S., Eccles, D.M., Tang, N., Olah, E., Nton-Culver, H., Warner, E., Lubinski, J., Gronwald, J., Gorski, B., Tulinius, H., Thorlacius, S., Eerola, H., Nevanlinna, H., Syrjakoski, K., Kallioniemi, O.P., Thompson, D., Evans, C., Peto, J., Lalloo, F., Evans, D.G. and Easton, D.F.
    Published:
    2005
    Publication:
    Journal of Medical Genetics
    Volume:
    42, (7)
    Page Range:
    602-603
    doi:
    10.1136/jmg.2004.024133
  • No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer - Campbell, I.G., Eccles, D.M. and Choong, D.Y.
    Published:
    2005
    Publication:
    Cancer Letters
    Volume:
    17
  • Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: A prospective multicentre cohort study (MARIBS) - Leach, M.O., Boggis, C.R., Dixon, A.K., Easton, D.F., Eeles, R.A., Evans, D.G., Gilbert, F.J., Griebsch, I., Hoff, R.J., Kessar, P., Lakhani, S.R., Moss, S.M., Nerurkar, A., Padhani, A.R., Pointon, L.J., Thompson, D., Warren, R.M. and MARIBS, study group
    Published:
    2005
    Publication:
    Lancet
    Volume:
    365, (9473)
    Page Range:
    1769-1778
    doi:
    10.1016/S0140-6736(05)66481-1
  • Familial non-BRCA1/BRCA2-associated breast cancer - Eccles, D.M. and Pichert, G.
    Published:
    2005
    Publication:
    The lancet oncology
    Volume:
    6, (9)
    Page Range:
    705-711
    doi:
    10.1016/S1470-2045(05)70318-1
  • Evaluation of RAD50 in familial breast cancer predisposition - Tommiska, J., Seal, S., Renwick, A., Barfoot, R., Baskcomb, L., Jayatilake, H., Bartkova, J., Tallila, J., Kaare, M., Tamminen, A., Heikkila, P., Evans, D.G., Eccles, D., Aittomaki, K., Blomqvist, C., Bartek, J., Stratton, M.R., Nevanlinna, H. and Rahman, N.
    Published:
    2005
    Publication:
    International Journal of Cancer
    Volume:
    118, (11)
    Page Range:
    2911-2916
    doi:
    10.1002/ijc.21738
  • Screening for familial ovarian cancer: failure of current protocols to detect ovarian cancer at an early stage according to The International Federation of Gynecology and Obstetrics System. - Stirling, Diane, Evans, D. Gareth, Pichert, Gabriella, Shenton, Andrew, Kirk, Elaine N., Rimmer, Sylvia, Steel, C. Michael, Lawson, Sheila, Busby-Earle, R. M. Camille, Walker, Jane, Lalloo, Fiona I., Eccles, Diana M., Lucassen, Anneke M. and Porteous, Mary E.
    Published:
    2005
    Publication:
    Journal of Clinical Oncology
    Volume:
    23, (24)
    Page Range:
    5588-5596
    doi:
    10.1200/JCO.2005.05.097
  • BRCA1 mutation and neuronal migration defect: Implications for chemoprevention - Eccles, D., Bunyan, D., Barker, S. and Castle, B.
    Published:
    2005
    Publication:
    Journal of Medical Genetics
    Volume:
    42, (e24)
    doi:
    10.1136/jmg.2004.028084
  • RNA analysis reveals splicing mutations and loss of expression defects in MLH1 and BRCA1 - Sharp, Andrew, Pichert, Gabriella, Lucassen, Anneke and Eccles, Diana
    Published:
    2004
    Publication:
    Human Mutation
    Volume:
    24, (3)
    Page Range:
    272-272
    doi:
    10.1002/humu.9267
  • A randomised comparison of UK genetic risk counselling services for familial cancer: psychosocial outcomes - Hopwood, P., Wonderling, D., Watson, M., Cull, A., Douglas, F., Cole, T., Eccles, D., Gray, J., Murday, V., Steel, M., Burn, J. and McPherson, K.
    Published:
    2004
    Publication:
    British Journal of Cancer
    Volume:
    91, (5)
    Page Range:
    884-892
    doi:
    10.1038/sj.bjc.6602081
  • Non-uptake of predictive genetic testing for BRCA1/2 among relatives of known carriers: attributes, cancer worry, and barriers to testing in a multicenter clinical cohort - Foster, C., Evans, D. G., Eeles, R., Eccles, D., Ashley, S., Brooks, L., Cole, T., Cook, J., Davidson, R., Gregory, H., Mackay, J., Morrison, P. J. and Watson, M.
    Published:
    2004
    Publication:
    Genetic Testing
    Volume:
    8, (1)
    Page Range:
    23-29
    doi:
    10.1089/109065704323016003
  • A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO - Evans, D. G. R., Eccles, D. M., Rahman, N., Young, K., Bulman, M., Amir, E., Shenton, A., Howell, A. and Lalloo, F.
    Published:
    2004
    Publication:
    Journal of Medical Genetics
    Volume:
    41, (6)
    Page Range:
    474-480
  • The DNMT3B C?T promoter polymorphism and risk of breast cancer in a British population: a case-control study - Montgomery, Karen G., Liu, Mira C.P., Eccles, Diana M. and Campbell, Ian G.
    Published:
    2004
    Publication:
    Breast Cancer Research
    Volume:
    6, (4)
    Page Range:
    R390-R394
    doi:
    10.1186/bcr807
  • Dosage analysis of cancer predisposition genes by multiplex ligation-dependent probe amplification - Bunyan, D.J., Eccles, D.M., Sillibourne, J., Wilkins, E., Thomas, N. Simon, Shea-Simonds, J., Duncan, P.J., Curtis, C.E., Robinson, D.O., Harvey, J.F. and Cross, N.C.P.
    Published:
    2004
    Publication:
    British Journal of Cancer
    Volume:
    91, (6)
    Page Range:
    1155-1159
    doi:
    10.1038/sj.bjc.6602121
  • Use of Pyrosequencing technology to quantitate allele expression in patients with BRCA1 mutations - Copson, E., White, H.E., Cross, N.C.P., Eccles, D. and Robinson, D.O.
    Published:
    2004
    Publication:
    Journal of Medical Genetics
    Volume:
    41
    Page Range:
    pp.S72
  • Hereditary cancer: guidelines in clinical practice. Breast and ovarian cancer genetics - Eccles, D.M.
    Published:
    2004
    Publication:
    Annals of Oncology
    Volume:
    15, (4)
    Page Range:
    iv133-iv138
    doi:
    10.1093/annonc/mdh917
  • Primary fibroblasts from BRCA1 heterozygotes display an abnormal G1/S cell cycle checkpoint following UVA irradiation but show normal levels of micronuclei following oxidative stress or mitomycin C treatment - Shorrocks, Julie, Tobi, Simon E., Latham, Harry, Peacock, John H., Eeles, Ros, Eccles, Diana and McMillan, Trevor J.
    Published:
    2004
    Publication:
    International Journal of Radiation Oncology, Biology, Physics
    Volume:
    58, (2)
    Page Range:
    470-478
    doi:
    10.1016/j.ijrobp.2003.09.042
  • Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice - Veugelers, Mark, Wilkes, David, Burton, Kimberly, McDermott, Deborah A., Song, Yan, Goldstein, Marsha M., La Perle, Krista, Vaughan, Carl. J., O'Hagan, Art, Bennett, Kenneth R., Meyer, Beat J., Legius, Eric, Karttunen, Mervi, Norio, Reijo, Kaariainen, Helena, Lavyne, Michael, Neau, Jean-Philippe, Richter, Gert, Kirali, Kaan, Farnsworth, Alan, Stapleton, Karen, Morelli, Peter, Takanashi, Yoshinori, Bamforth, John-Steven, Eitelberger, Franz, Noszian, Irene, Manfroi, Waldimiro, Powers, James, Mochizuki, Yoshihiko, Imai, Tsuneo, Ko, Gary T. C., Driscoll, Deborah A., Goldmuntz, Elizabeth, Edelberg, Jay M., Collins, Amanda, Eccles, Diana, Irvine, Alan D., McKnight, G. Stanley and Basson, Craig T.
    Published:
    2004
    Publication:
    Proceedings of the National Academy of Sciences of the United States of America
    Volume:
    101, (39)
    Page Range:
    14222-14227
    doi:
    10.1073/pnas.0405535101
  • Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH - Sampson, Julian R., Dolwani, Sunil, Jones, Sian, Eccles, Diana, Ellis, Anthony, Evans, D. Gareth, Frayling, Ian, Jordan, Sheila, Maher, Eamonn R., Mak, Tony, Maynard, Julie, Pigatto, Francesco, Shaw, Joan and Cheadle, Jeremy P.
    Published:
    2003
    Publication:
    The Lancet
    Volume:
    362, (9377)
    Page Range:
    39-41
    doi:
    10.1016/S0140-6736(03)13805-6
  • Evaluation of Fanconi Anemia genes in familial breast cancer predisposition - Seal, Sheila, Barfoot, Rita, Jayatilake, Hiran, Smith, Paula, Renwick, Anthony, Bascombe, Linda, McGuffog, Lesley, Evans, D. Gareth, Eccles, Diana, Easton, Douglas F., Stratton, Michael R. and Rahman, Nazneen
    Published:
    2003
    Publication:
    Cancer Research
    Volume:
    63, (24)
    Page Range:
    8596-8599
  • Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome - Lim, W., Hearle, N., Shah, B., Murday, V., Hodgson, S.V., Lucassen, A., Eccles, D., Talbot, I., Neale, K., Lim, A.G., O'Donohue, J., Donaldson, A., Macdonald, R.C., Young, I.D., Robinson, M.H., Lee, P.W., Stoodley, B.J., Tomlinson, I., Alderson, D., Holbrook, A.G., Vyas, S., Swarbrick, E.T., Lewis, A.A., Phillips, R.K. and Houlston, R.S.
    Published:
    2003
    Publication:
    British Journal of Cancer
    Volume:
    89, (2)
    Page Range:
    308-313
    doi:
    10.1038/sj.bjc.6601030
  • Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies - Antoniou, A., Pharoah, P.D.P., Narod, S., Risch, H.A., Eyfjord, J.E., Hopper, J.L., Loman, N., Olsson, H., Johannsson, O., Borg, A., Pasini, B., Radice, P., Manoukian, S., Eccles, D.M., Tang, N., Olah, E., Anton-Culver, H., Warner, E., Lubinski, J., Gronwald, J., Gorski, B., Tulinius, H., Thorlacius, S., Eerola, H., Nevanlinna, H., Syrjäkoski, K., Kallioniemi, O.-P., Thompson, D., Evans, C., Peto, J., Lalloo, F., Evans, D.G. and Easton, D.F.
    Published:
    2003
    Publication:
    American Journal of Human Genetics
    Volume:
    72, (5)
    Page Range:
    1117-1130
  • Prohibitin 3' untranslated region polymorphism and breast cancer risk - Campbell, Ian G., Allen, James and Eccles, Diana M.
    Published:
    2003
    Publication:
    Cancer Epidemiology Biomarkers & Prevention
    Volume:
    12
    Page Range:
    1273-1274
  • Neuronal migration defect in a BRCA1 gene carrier: possible focal nullisomy? - Eccles, D. M., Barker, S., Pilz, D. T. and Kennedy, C.
    Published:
    2003
    Publication:
    Journal of Medical Genetics
    Volume:
    40, (e24)
  • Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility - Schutte, Mieke, Seal, Sheila, Barfoot, Rita, Meijers-Heijboer, Hanne, Wasielewski, Marijke, Evans, D. Gareth, Eccles, Diana, Meijers, Carel, Lohman, Frans, Klijn, Jan, van den Ouweland, Ans, Futreal, P. Andrew, Nathanson, Katherine L., Weber, Barbara L., Easton, Douglas F., Stratton, Michael R. and Rahman, Nazneen
    Published:
    2003
    Publication:
    American Journal of Human Genetics
    Volume:
    72, (4)
    Page Range:
    1023-1028
  • Genetic testing for BRCA1 mutation in the UK - Eccles, Diana M.
    Published:
    2003
    Publication:
    The Lancet
    Volume:
    361, (9352)
    Page Range:
    178-179
    doi:
    10.1016/S0140-6736(03)12213-1
  • Apoptosis, ageing and cancer susceptibility - Camplejohn, R.S., Gilchrist, R., Easton, D., McKenzie-Edwards, E., Barnes, D.M., Eccles, D.M., Ardern-Jones, A., Hodgson, S.V., Duddy, P.M. and Eeles, R.A.
    Published:
    2003
    Publication:
    British Journal of Cancer
    Volume:
    88, (4)
    Page Range:
    487-490
    doi:
    10.1038/sj.bjc.6600767
  • Increased colorectal cancer incidence in obligate carriers of heterozygous mutations in MUTYH - Jones, Natalie, Vogt, Stefanie, Nielsen, Maartje, Christian, Daria, Wark, Petra A., Eccles, Diana, Edwards, Emma, Evans, D. Gareth, Maher, Eamonn R., Vasen, Hans F., Hes, Frederik J., Aretz, Stefan and Sampson, Julian R.
    Published:
    2002
    Publication:
    Gastroenterology
    Volume:
    137, (2)
    Page Range:
    489-494
    doi:
    10.1053/j.gastro.2009.04.047
  • Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer - Campbell, Ian G., Baxter, Simon W., Eccles, Diana M. and Choong, David Y. H.
    Published:
    2002
    Publication:
    Breast Cancer Research
    Volume:
    4, (6)
    doi:
    10.1186/bcr457
  • Transforming growth factor ? receptor 1 polyalanine polymorphism and exon 5 mutation analysis in breast and ovarian cancer - Baxter, Simon W., Choong, David Y.H., Eccles, Diana M. and Campbell, Ian G.
    Published:
    2002
    Publication:
    Cancer Epidemiology, Biomarkers & Prevention
    Volume:
    11, (2)
    Page Range:
    211-214
  • First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial - Cuzick, J., Forbes, J., Edwards, R., Baum, M., Cawthorn, S., Coates, A., Hamed, A., Howell, A., Powles, T. and Eccles, D. M.
    Published:
    2002
    Publication:
    The Lancet
    Volume:
    360, (9336)
    Page Range:
    817-824
    doi:
    10.1016/S0140-6736(02)09962-2
  • Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium - Thompson, Deborah, Szabo, Csilla I., Mangion, Jon, Oldenburg, Rogier A., Odefrey, Fabrice, Seal, Sheila, Barfoot, Rita, Kroeze-Jansema, Karin, Teare, Dawn, Rahman, Nazneen, Renard, Hélène, Mann, Graham, Hopper, John L., Buys, Saundra S., Andrulis, Irene L., Senie, Ruby, Daly, Mary B., West, Dee, Ostrander, Elaine, Offit, Ken, Peretz, Tamar, Osorio, Ana, Benitez, J., Nathanson, Katherine L., Sinilnikova, Olga M., Olàh, Edith, Bignon, Yves-Jean, Ruiz, Pablo, Badzioch, Michael D., Vasen, Hans F.A., Futreal, Andrew P., Phelan, Catherine M., Narod, Steven A., Lynch, Henry T., Ponder, Bruce A.J., Eeles, Ros A., Meijers-Heijboer, Hanne, Stoppa-Lyonnet, Dominique, Couch, Fergus J., Eccles, Diana M., Evans, D. Gareth, Chang-Claude, Jenny, Lenoir, Gilbert, Weber, Barbara L., Devilee, Peter, Easton, Douglas F., Goldgar, David E. and Stratton, Michael R.
    Published:
    2002
    Publication:
    Proceedings of the National Academy of Sciences of the United States of America
    Volume:
    99, (2)
    Page Range:
    827-831
    doi:
    10.1073/pnas.012584499
  • The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS) - Leach, M.O., Eeles, R.A., Turnbull, L.W., Dixon, A.K., Brown, J., Hoff, R.J., Coulthard, A., Dixon, J.M., Easton, D.F., Evans, D.G., Gilbert, F.J., Hawnaur, J., Hayes, C., Kessar, P., Lakhani, S., Liney, G., Moss, S.M., Padhani, A.P., Pointon, L.J., Sydenham, M., Walker, L.G., Warren, R.M., Haites, N.E., Morrison, P., Cole, T., Rayter, Z., Donaldson, A., Shere, M., Rankin, J., Goudie, D., Steel, C.M., Davidson, R., Chu, C., Ellis, I., Mackay, J., Hodgson, S.V., Homfray, T., Douglas, F., Quarrell, O.W., Eccles, D. M., Gilbert, F.G., Crothers, G., Walker, C.P., Jones, A., Slack, N., Britton, P., Sheppard, D.G., Walsh, J., Whitehouse, G., Teh, W., Rankin, S., Boggis, C., Potterton, J., McLean, L., Gordon, P.A. and Rubin, C.
    Published:
    2002
    Publication:
    Journal of Experimental and Clinical Cancer Research
    Volume:
    21, (3 Suppl)
    Page Range:
    107-114
  • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations - Meijers-Heijboer, Hanne, Van den, Ans, Klijn, Jan, Wasielewski, Marijke, De Snoo, Anja, Oldenburg, Rogier, Hollestelle, Antoinette, Houben, Mark, Crepin, Ellen, Van Veghel-Plandsoen, Monique, Elstrodt, Fons, Van Duijn, Cornelia, Bartels, Carina, Meijers, Carel, Schutte, Mieke, McGuffog, Lesley, Thompson, Deborah, Easton, Douglas F., Sodha, Nayanta, Seal, Sheila, Barfoot, Rita, Mangion, Jon, Chang-Claude, Jenny, Eccles, Diana, Eeles, Rosalind, Evans, D. Gareth, Houlston, Richard, Murday, Victoria, Narod, Steven, Peretz, Tamara, Peto, Julian, Phelan, Catherine, Zhang, Hong Xiang, Szabo, Csilla, Devilee, Peter, Goldgar, David, Futreal, P. Andrew, Nathanson, Katherine L., Weber, Barbara L., Rahman, Nazneen and Stratton, Michael R.
    Published:
    2002
    Publication:
    Nature Genetics
    Volume:
    31, (1)
    Page Range:
    55-59
    doi:
    10.1038/ng879
  • Familial breast cancer: an investigation into the outcome of treatment for early stage disease - Eccles, Diana, Simmonds, Peter, Goddard, Jonathan, Coultas, Marie, Hodgson, Shirley, Lalloo, Fiona, Evans, Gareth and Haites, Neva
    Published:
    2001
    Publication:
    Familial Cancer
    Volume:
    1, (2)
    Page Range:
    65-72
    doi:
    10.1023/A:1013867917101
  • Evidence based case report. Advice about mammography for a young woman with a family history of breast cancer - Lucassen, Anneke, Watson, Elia and Eccles, Diana
    Published:
    2001
    Publication:
    British Medical Journal
    Volume:
    322, (7293)
    Page Range:
    1040-1042
  • The application of microplate array diagonal gel electrophoresis (melt-MADGE) to high throughput inexpensive BRCA1 mutation analysis - Aldahmesh, M., Spanakis, E., Day, I.N.M. and Eccles, D.M.
    Published:
    2001
    Publication:
    Journal of Medical Genetics
    Volume:
    38
    Page Range:
    pp.S58
  • Skin spots and heart tumors - Reddy, T. Damodar, Eccles, Diana M., Theaker, Jeffrey, Keeton, Barry R. and Temple, Karen
    Published:
    2001
    Publication:
    Journal of Pediatrics
    Volume:
    139, (6)
    Page Range:
    901-902
    doi:
    10.1067/mpd.2001.119595
  • A novel 3' mutation in the APC gene in a family presenting with a desmoid tumour - Eccles, Diana, Harvey, John, Bateman, Adrian and Ross, Fiona
    Published:
    2001
    Publication:
    Journal of Medical Genetics
    Volume:
    38, (12)
    Page Range:
    861-863
  • Polymorphic variation in CYP19 and the risk of breast cancer - Baxter, S.W., Choong, D.Y.H., Eccles, D.M. and Campbell, I.G.
    Published:
    2001
    Publication:
    Carcinogenesis
    Volume:
    22, (2)
    Page Range:
    347-349
  • Minisatellite instability is found in colorectal tumours with mismatch repair deficiency - Gough, A.C., Coleman, M.G., Bunyan, D.J., Braham, D., Eccles, D.M. and Primrose, J.N.
    Published:
    2001
    Publication:
    British Journal of Cancer
    Volume:
    85, (10)
    Page Range:
    1486-1491
    doi:
    10.1054/bjoc.2001.2058
  • Fibroadenoma with atypical giant cells occurring in Li Fraumeni Syndrome - Parham, D.M. and Eccles, D.M.
    Published:
    2001
    Publication:
    The Breast
    Volume:
    10, (4)
    Page Range:
    330-332
    doi:
    10.1054/brst.2000.0250
  • First case report of Muir-Torre syndrome associated with non-small cell lung cancer - Nolan, L., Eccles, D., Cross, E., Crawford, G., Beck, N., Bateman, A. and Ottensmeier, C.
    Published:
    1970
    Publication:
    Familial Cancer
    Volume:
    8, (4)
    Page Range:
    359-362
    doi:
    10.1007/s10689-009-9247-7

Book Section(s)

Conference(s)

Professor Eccles delivers the Cancer Genetics lecture in Semester 4 for the BM5 students and acts as personal tutor to undergraduate medical students as they progress through the course.

Professor Eccles’ main teaching commitment is to training at specialist and F2 level in Clinical Genetics, she is the Wessex Regional Specialist Advisor for Genetics Foundation year 2 lead tutor for Clinical Genetics. Nationally she is the Academic Vice President of the Clinical Genetics Society and a member of the RCP Specialist Advisory Committee for Clinical Genetics. She also advises on genetic education in the Oncology trainees curriculum and is involved in training for oncology registrars in the Wessex Region.

As an expert in Cancer genetics, Professor Eccles is a regular faculty member at a variety of national and international educational fora including the European Society for Medical Oncology conference, European School of Oncology, the European School of Human Genetics and the Anglo-Indian Genetics Collaboration.

Professor Diana Eccles
Phone: (023) 8120 8537 Fax: (023) 8120 4346 Email: d.m.eccles@soton.ac.uk

Room Number: PAH/G/MP105

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