BSc Biochemistry, University of Birmingham; PhD Biochemistry, University of Birmingham; Chartered Biologist (CBiol); Fellow of the Society of Biology (FSB); Fellow of the American Academy of Microbiology (FAAM); Fellow of the World Innovation Foundation (FWIR); Fellow of the Royal Society of Medicine (FRSM)
- Primary position:
- Chair in Environmental Healthcare
- Other positions:
- Principal Investigator (Microbiology & environmental health), Director of the Environmental Healthcare Unit, Chair of the University Genetic Manipulation and Safety Committee
Head of the Microbiology Group and Director of the Environmental Healthcare Unit. University of Southampton, UK.
Visiting Professor of Microbiology. University of Exeter, UK.
Head of the Environmental Technology Department. Centre for Microbiology and Research, Salisbury, UK.
Scientific Advisor to the House of Commons Select Committee on Science & Technology, London, UK.
Visiting Research Fellow, University of Manitoba, Canada.
Postdoctoral Fellow, University of Southampton, UK.
The University of Southampton's electronic library (e-prints)
Conference or Workshop Item
- Physiology and adaptive mechanisms for survival of pathogens, in vivo and in vitro e.g. Legionella, Helicobacter, E. coli O157, MRSA, C. difficile.
- Biofilms in the environment, the built environment and clinical practice.
- Surface contamination, including prions; fouling and corrosion.
Survival of sublethally damaged pathogens in water and human and animal wastes recycled to agricultural land, e.g. E coli O157 Salmonella, Campylobacter, Listeria, Cryptosporidium
Tom Secker: BBSRC Industrial CASE student / Development of rapid, sensitive neuroblastoma and stem cell culture systems to assess the efficacy of prion decontamination technologies.
Nicola Gibbins: BBSRC Industrial CASE student / Role of nitric oxide in the control of biofilm and zoonotic pathogen colonisation on the salad leaf phylloplane.
Aaron Dye: EC FP7 student / FeS production by sulphate reducing bacteria for the decontamination of radionuclides in drinking water.
David Walker: EC FP7 student / Biofilm prevention on microfluidic sensor devices.
Affiliated research Group: Institute of Life Sciences
Primary research group: Environmental Biosciences
Affiliate research group: Institute for Life Sciences (IfLS)
Using microscopy and molecular community analysis techniques, the effects of antifouling methods will be assessed.
This project will assess the cleanliness of existing endoscopes and the efficacy of current decontamination procedures, using a new highly sensitive microscopy imaging method to identify and quantify residual contamination from a range of flexible endoscopes, and new cell assays to assess potential prion infectivity.
Antimicrobial copper: Biocidal efficacy and killing mechanism of copper and copper alloy dry surfaces against bacterial and viral pathogens
Touch surfaces are an important conduit for transmission of bacteria, viruses and fungi, leading to mass outbreaks of disease in the community and healthcare acquired infections by multiple antibiotic resistant microorganisms causing great morbidity and mortality.
BioliSME II: Demonstration, validation and preliminary promotion of a commercial prototype speedy system for sampling and detecting Listeria monocytogenes
The objective of the work developed by the partner University of Southampton is to firstly optimize the formation of L. monocytogenes biofilms and then conduct experiments to calculate the detachment forces required to remove L. monocytogenes biofilms.
To evaluate the potential of Cold Atmospheric Plasma as a tool for the decontamination of reusable surgical instruments and endoscopes, thus significantly reducing the risk of iatrogenic infections with prions and potentially other resilient agents.
Development of anti-fouling strategies for long-term deployed in situ sensors in marine environments
Analysis of biofilms in the marine environment and of the effectiveness of antifouling strategies
Our Consultancy Service has dealt with a wide range of projects in collaboration with both small and large multinational companies.We offer a range of testing services using up-to-date microbiological methods and the latest techniques in specialised microscopy.
Using the model organism Pseudomonas aeruginosa to investigate mechanisms by which drinking water biofilms harbour important pathogenic microorganism and how these interactions within multi-species biofilms can enhance genetic adaptation and evolution of microbial pathogens.
Development of rapid, sensitive, advanced EDIC/EF light microscopy based protocols to assess the efficacy of current bio-decontamination systems.
Using a multicellular tumour spheroid model to investigate the role of hypoxia and DNA mismatch repair on the fundamental processes of importance in tumour development
The role of nitric oxide in the control of biofilm and zoonotic pathogen colonisation of the salad phylloplane
Investigating the use of the signalling molecule nitric oxide for microbial control at the phylloplane
SecurEau – Security and decontamination of drinking water distribution systems following a deliberate contamination event.
This work aims to design novel methodologies for the detection of low levels of contaminants, model the distribution of contaminants throughout a network and identify the point of origin, develop the use of sensors for surveillance and provide decontamination protocols for polluted networks and installations, including the neutralisation of contaminated water and residues.
Biofilm development on urinary catheters is a major healthcare issue, leading to infection and blockage. Here we are using advanced microscopy and viability techniques to improve our understanding of biofilm development and persistence on urinary catheters.
BIOL1007 The Molecular basis of Life I
BIOL2022 Immunology, Infection and Inflammation
BIOL2038 Microbiology - From the Natural Environment to Disease
BIOL3017 The Molecular Structural Basis of Disease
BIOL3057 Biofilms and Microbial Communities
Member of EPSRC National Centre for Advanced Tribology (nCATS) Management Board
CfBS Liaison Officer with Society of Biology, London
MOD Independent Scientific and Technical Advice (ISTA) Register
DEFRA Drinking Water Inspectorate Rapid Methods Committee, London
DoH Decontamination Working Group, London
IWW Rheinisch-Westfaelisches Institut für Wasser, Mulheim, External Management Board
CEN TC308 WG1 Committee, Brussels
British Standards Institute EH/5 Wastes Committee, London