I completed my undergraduate degree in Newcastle upon Tyne before heading to another Newcastle, this time in Australia to undertake a PhD. There I wrote my thesis on chromosome division in oocytes, a highly specialised division with clinical relevance to the origin of trisomies (like Down Syndrome) and to miscarriage.
In Newcastle I developed techniques for automated, 3D imaging of cells expressing multiple fluorescently-tagged proteins using timelapse microscopy. Now in Southampton I use this approach to track the movements and destruction of various proteins throughout the cell cycle, helping to further our understanding of the molecular mechanisms behind chromosome segregation.
Affiliate research group(s)
Institute for Life Sciences (IfLS)
Understanding how mammalian oocytes sense and repair damage to their DNA
Dr Simon I.R. Lane
Faculty of Natural & Environmental Sciences
Life Sciences Building 85
University of Southampton