Centre for Biological Sciences

BIOL3052 Biomedical Technology

Module Overview

This course is designed to illustrate the ways in which the theoretical principles of biochemistry, cellular and molecular biology presented in previous courses can be applied to yield important commercial or therapeutic products or processes.

Module Details

Title: Biomedical Technology
Code: BIOL3052
Year: 3
Semester: 2

CATS points: 15 ECTS points: 7.5
Level: Level 6
Co-ordinator(s): Prof Karen A Lillycrop

Aims and objectives

This course is designed to illustrate the ways in which the theoretical principles of biochemistry, cellular and molecular biology presented in previous courses can be applied to yield important commercial or therapeutic products or processes.

  1. Describe the use of DNA aptamers in biotechnology
  2. Explain the methodology used to study genome wide changes in the transcriptome
  3. Explain the use of gene cloning to produce recombinant proteins in both prokaryotic and eukaryotic hosts
  4. Explain the use of stem cells and their use in medical applications
  5. Describe how gene therapy can be used, to treat human disease and how liposomes and viruses can be used to deliver the gene of interest
  6. Describe how antibody engineering can be used to treat human disease
  7. Describe the use of ScFvs in the design of human monoclonal antibodies

Syllabus

It concentrates on biotechnology that involves prokaryotic and eukaryotic cells. It introduces students to the technologies of the “post genomic” era. It also presents examples of protein engineering, the manipulation of the characteristics of protein molecules such as antibodies and antibody-binding proteins. The course also includes material of the production of therapeutic proteins, the use of gene therapy and stem cells to treat human disease.

Learning and teaching

Study time allocation

Contact hours: 24
Private study hours: 126
Total study time: 150 hours

Teaching and learning methods

This course comprises 20 lectures with 4 feedback/revision seminars. For each section of the course the student is given a comprehensive reading list of recent research and review papers. Examination is by a 2 hour written examination.

Assessment

Assessment methods

Assessment Method Summative / Formative % contribution to final mark  Final element of assessment (√) 
Examination: 2 hours. The format of the paper is two questions out of three, where one answer is an either/or.  Summative 100%
Re-assessment Method
Include duration of exams, whether the assessment is formative or summative and whether there are any elements that must be passed for successful completion of the module.
Summative / Formative % contribution to final mark Final element of assessment (√)
Examination: 2 hours. The format of the paper is two questions out of three, where one answer is an either/or. summative 100%