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Engineering and the Environment

Research project: MXL project – Improving Joint Surgery

Currently Active: 

‘MXL’ is short for “Enhanced patient safety by computational Modelling from clinically available X-rays to minimise the risk of overload and instability for optimised function and Longevity”. This is an international EU-funded project which the Bioengineering Sciences Research Group at Southampton is involved in. For more information, visit MXL.

Project Overview

MXL Improving Joint Surgery
MXL Project

The MXL project addresses the specific aims and objectives of the ICT-2009.5.2: ICT for Patient Safety call by implementing an ICT framework that provides the surgeon with quantitative data to minimize the risk of joint overload and instability, thereby preserving the joint.

The objective is to develop training and planning tools to provide the surgeon with an accurate, patient specific prediction of the outcome of joint surgery. MXL will transform the clinical management of joint surgery by implementing a combination of image processing, finite element and musculoskeletal modelling tools to provide an understanding of the individual biomechanical condition from standard clinical radiographs.

The innovative ICT framework will enable the safe management of joint surgery throughout all stages of joint degeneration, with a focus on minimizing key failure risks of surgery. Thereby, even less experienced surgeons will be enabled to identify and implement a safe surgical route to optimal functional outcome for each and every patient, be it surgery to preserve a joint afflicted by instability due to ruptured ligaments, or to replace an already degenerated joint using artificial components. The targeted ICT framework will capitalize on using standard X-ray imaging to reduce costs and avoid unnecessary disruption to the standard clinical work flow. This guarantees widespread access for patients to this improved quality of care and addresses a key societal challenge of our ageing society.

MXL is partially funded by the European Information and Communication Technologies Community Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 248693.

• Centre for Musculoskeletal Surgery,Charité, University Medicine, Free and Humboldt University, Berlin, Germany
• Bioengineering Sciences Group, University of Southampton, UK
• Leiden University Medical Centre, the Netherlands
• Euram Limited, Nottinghamshire, UK
• ESI Group, Rungis, France
• Zuse Institute Berlin (ZIB), Berlin, Germany
• DELFT University of Technology, the Netherlands
• Istituto Ortopedico Rizzoli (IOR), Bologna, Italy
• SuperComputingSolutions (SCS), Milan, Italy
• MEDIS Specials, Leiden, The Netherlands

Martin Browne
Bioengineering Sciences Group
School of Engineering Sciences
University of Southampton
SO17 1BJ
United Kingdom

Related research groups

Bioengineering Science
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