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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood

Professor Keith Godfrey

Associate Dean Enterprise

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Influence of maternal lifestyle and diet on perinatal DNA methylation signatures associated with childhood arterial stiffness at 8 to 9 years
Robert Murray,
Negusse Kitaba,
Elie Antoun,
Philip Titcombe,
Sheila Barton,
Cyrus Cooper,
Hazel M. Inskip,
Graham C. Burdge,
Pamela A. Mahon,
John Deanfield,
Julian P. Halcox,
Elizabeth A. Ellins,
Jennifer Bryant,
Charles Peebles,
Karen Lillycrop,
Keith M. Godfrey,
Mark A. Hanson,
& Epi Gen Consortium
, 2021 , Hypertension , 78 (3) , 787--800
DOI: 10.1161/HYPERTENSIONAHA.121.17396
Type: article
Determinants of cord blood adipokines and association with neonatal abdominal adipose tissue distribution
Karen Mei Ling Tan,
Mya Thway Tint,
Navin Michael,
Fabian Yap,
Yap-Seng Chong,
Kok Hian Tan,
Keith Godfrey,
Anis Larbi,
Yung Seng Lee,
Shiao-Yng Chan,
Marielle V. Fortier,
Johan G. Eriksson,
& Neerja Karnani
, 2021 , International Journal of Obesity
DOI: 10.1038/s41366-021-00975-3
Type: article
Metabolic health status and fecundability in a Singapore preconception cohort study
S.L. Loy,
Daniel Wei Keong Chan,
Chee Wai Ku,
Yin Bun Cheung,
Keith Godfrey,
Karen Mei Ling Tan,
Yap-Seng Chong,
Lynette P. Shek,
Kok Hian Tan,
Shiao-Yng Chan,
Jerry Kok Yen Chan,
& Fabian Yap
, 2021 , American Journal of Obstetrics and Gynecology
DOI: 10.1016/j.ajog.2021.11.1374
Type: article
Longitudinal dietary trajectories from preconception to mid-childhood in women and children in the Southampton Women’s Survey and their relation to offspring adiposity: a group-based trajectory modelling approach
Kathryn V. Dalrymple,
Christina Vogel,
Keith Godfrey,
Janis Baird,
Nicholas Harvey,
Mark Hanson,
Cyrus Cooper,
Hazel Inskip,
& Sarah Crozier
, 2021 , International Journal of Obesity
DOI: 10.1038/s41366-021-01047-2
Type: article
Epigenome-wide association study of sarcopenia
Elie Antoun,
Emma Garratt,
Andrea Taddei,
Mark Burton,
Sheila Barton,
Philip Titcombe,
,
Leo Westbury,
Alicia Baczynska,
Eugenia Migliavacca,
Jerome N. Feige,
Holly Emma Syddall,
Elaine Dennison,
Richard Dodds,
Helen Roberts,
Peter Richardson,
Avan A. Sayer,
Sarah Shaw,
Cyrus Cooper,
Joanna D. Holbrook,
Harnish Patel,
Keith Godfrey,
& Karen Lillycrop
, 2021 , Journal of Cachexia, Sarcopenia and Muscle , 13 (1) , 240 -- 253
DOI: 10.1002/jcsm.12876
Type: article