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Research project

Prof Keith Fox BBSRC Scibs Triplex SoBS

Staff

Lead researcher

Emeritus Professor Keith Fox

Research interests

  • DNA Interactions
  • Triplex DNA
  • Quadruplex DNA
Other researchers

Professor Lindy Holden-Dye BSc, MSc, PhD, FRSB, FBPhS

PROFESSOR OF NEUROSCIENCES

Research interests

  • Neuropharmacology
  • Invertebrate neuroscience
  • Nematode neurobiology

Research outputs

Formation of stable DNA triplexes
Keith R. Fox,
& Tom Brown
, 2011 , Biochemical Society Transactions , 39 (2) , 629--634
DOI: 10.1042/BST0390629
Type: article
2?-aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation
Chenguang Lou,
Montserrat Shelbourne,
Keith R. Fox,
& Tom Brown
, 2011 , Chemistry - A European Journal , 17 (52) , 14851--14856
DOI: 10.1002/chem.201102287
Type: article
CG base pair recognition within DNA triple helices by modified N-methylpyrrolo-dC nucleosides
Simon R. Gerrard,
Mastoura M. Edrees,
Imenne Bouamaied,
Keith R. Fox,
& Tom Brown
, 2010 , Organic & Biomolecular Chemistry , 8 (22) , 5087--5096
DOI: 10.1039/c0ob00119h
Type: article
Synthesis and properties of triplex-forming oligonucleotides containing 2'-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine
Chenguang Lou,
Qiang Xiao,
Lavinia Brennan,
Mark E. Light,
Nuria Vergara-Irigaray,
Elizabeth M. Atkinson,
Lindy M.. Holden-Dye,
Keith R. Fox,
& Tom Brown
, 2010 , Bioorganic & Medicinal Chemistry , 18 (17) , 6389--6397
DOI: 10.1016/j.bmc.2010.07.005
Type: article
Potent triple helix stabilization by 5?,3?-modified triplex-forming oligonucleotides
Nouha Ben Gaied,
Zhengyun Zhao,
Simon R. Gerrard,
Keith R. Fox,
& Tom Brown
, 2009 , ChemBioChem , 10 (11) , 1839--1851
DOI: 10.1002/cbic.200900232
Type: article