The Cellular and Molecular Biosciences staff pursue a range of externally-funded projects within five broad research themes: the molecular organisation of proteins and nucleic acids; developmental biology and its influence on adult health and disease; cell signalling pathways controlling gene expression, cell growth and cell division; plant growth and environmental interactions; membrane proteins and cellular function.
We collaborate closely with researchers across the University and with investigators around the world. For example, we work with physical scientists and engineers to investigate biomolecules as substrates for the production of novel materials and our joint projects with staff in Medicine aim to understand the origins of disease.
Within the School of Biological Sciences, we have a wealth of modern facilities. We are well equipped for structural (X-ray and NMR) and biophysical studies of proteins and nucleic acids and have a superb Proteomics facility which includes a range of state-of-the-art mass spectrometers. The Bioimaging Facility comprises a range of modern microscopes including confocal and multiphoton instruments, allowing the use of Fluorescence Correlation Spectroscopy techniques.
We are housed within the new, purpose-built Life Sciences Building on the University's Highfield campus and at the Southampton General Hospital campus.
Molecular and Cellular Biosciences Principle Investigators (PI)
Dr Mark Coldwell: PI Cellular and molecular biosciences
Dr Katrin Deinhardt: PI Cellular Neurobiology
Professor Malcolm East: PI Membrane proteins
Professor Keith Fox: PI Nucleic Acids
Dr Haruko Okamoto: PI Plant Molecular Genetics & Biochemistry
Dr Paul Skipp: PI Proteomics
Dr Ivo Tews: PI Protein interactions & cell membranes
Dr Jeremy Webb: PI Microbial biofilms
Dr Joern Werner: PI Protein-ligand interactions
Dr Herman Wijnen Associate Professor: PI Biological timing
Dr Phil Williamson: PI Structural biology and biological membranes
Dr Lorraine Williams: PI Membrane transporters