The University of Southampton
Courses

BIOL6037 Pathophysiology of the lung

Module Overview

This module gives students a sound background in modern molecular medicine using examples from pulmonary health and disease. The module focuses on three common lung diseases, asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis and seeks to outline the pathology of these three very distinct lung diseases and different approaches to their treatment. It will also highlight the ability of different external or genetic factors to influence outcomes in chronic lung disease. Students will attend research seminars and evaluate examples of current research in this field.

Aims and Objectives

Module Aims

The aim of this module is to give students a sound background in modern molecular medicine using examples from pulmonary health and disease. The module focuses on three common lung diseases, asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis and seeks to outline the pathology of these three very distinct lung diseases and different approaches to their treatment. It will also highlight the ability of different external or genetic factors to influence outcomes in chronic lung disease. Students will attend research seminars and evaluate examples of current research in this field.

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Explain the role of different cell types in allergic disease.
  • Discuss the implications of a sample of current research in this field for our understanding of lung disease
  • Identify the pathways responsible for the synthesis of immunoglobulin E
  • Identify the major pharmacological targets available to treat allergy and asthma and emerging therapeutic targets.
  • Discuss our current understanding of the influence of early life factors on the development of allergic disease.
  • Describe the main characteristics of chronic obstructive pulmonary disease (COPD) and current hypotheses pertaining to its pathology.
  • Identify the problems associated with treating COPD and some of the potential therapeutic strategies.
  • Identify the different ways in which viral infections can exacerbate airways disease
  • Describe the clinical symptoms and cellular pathology underlying cystic fibrosis.
  • Discuss the concepts and technical approaches to cystic fibrosis therapy

Syllabus

• Information transfer in the nervous system • Ligand-gated channels & G-protein coupled Receptors • Mechanisms and modulation of synaptic neurotransmitter release • Voltage-gated channels • Axon guidance

Special Features

Students will attend scheduled seminars based around selected research papers, these seminars will be chaired by an academic. Students will be required to study the papers in detail beforehand and will be assigned papers to present to the group for discussion. Following the seminars the student will prepare their written critical evaluation of an assigned paper and submit it via Turnitin. In the final seminar session the student will make a formal presentation of their evaluation to a peer group and academic assessor. Students are also encouraged to enter into informal discussions with teaching staff and utilise computer-based material to facilitate learning of core principles of membrane excitation.

Learning and Teaching

Teaching and learning methods

Lectures, research paper seminars and independent study

TypeHours
Seminar4
Independent Study122
Lecture24
Total study time150

Assessment

Summative

MethodPercentage contribution
Literature review with presentation  (1500 words) 35%
Written exam  (2 hours) 65%

Referral

MethodPercentage contribution
Literature review with presentation 35%
Written exam  (2 hours) 65%

Linked modules

Prerequisites: BIOL2014 or BIOL2010 or BIOL2011 or MEDI6221

Share this module Facebook Google+ Twitter Weibo

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×