Medicine

Philip Calder

BSc(Hons), PhD, DPhil, RNutr, FSB, FAfN

Primary position:
Professor of Nutritional Immunology

Background

The University of Southampton

Professor Calder was appointed to a personal Chair in Nutritional Immunology in 2002. His research focuses on understanding the influence of dietary fatty acids on aspects on cell function and human health, in particular in relation to cardiovascular disease, inflammation and immunity. He has been awarded the Sir David Cuthbertson Medal by the UK Nutrition Society (1995), the Belgian Danone Institute Chair (2004), the Nutricia International Award (2007), the ESPEN Cuthbertson Lecture (2008), the New Zealand Nutrition Society’s Muriel Bell Award (2009), the Louisiana State University Chancellor’s Award in Neuroscience and Medicine (2011) and the German Society for Fat Research’s Normann Medal (2012). Professor Calder has over 400 research publications (excluding abstracts) and is listed on isiHighlyCited. He has served on various committees and expert panels. He served for seven years as Editor-in-Chief of the British Journal of Nutrition and is currently an Associate Editor of Clinical Science and of Lipids. He is a member of the several other Editorial Boards. Professor Calder is a Fellow of the Society for Biology and of the Association for Nutrition.

Qualifications

BSc(Hons), Biochemistry, Massey University (1980)
PhD, Biochemistry, University of Auckland (1987)
DPhil, Biochemistry, University of Oxford (1995)

Appointments held

Nuffield Medical Fellow, Department of Biochemistry, University of Oxford, 1987-1991

Departmental Lecturer, Department of Biochemistry, University of Oxford, 1991-1995

Lecturer in Human Nutrition, University of Southampton, 1995-1998

Reader in Human Nutrition, University of Southampton, 1998-2002

Professor of Nutritional Immunology, University of Southampton, 2002-present

 

Professor Philip Calder's photo

Publications

The University of Southampton's electronic library (e-prints)

Article

Sorensen , L.S., Rasmussen , H.H., Aardestrup, I.V., Thorlacius-Ussing, O., Lindorff-Larsen, K., Schmidt, E.B. and Calder, P.C. (2014) Rapid incorporation of ω-3 fatty acids into colonic tissue after oral supplementation in patients with colorectal cancer: a randomized, placebo-controlled intervention trial. Journal of Parenteral and Enteral Nutrition, 38, (5), 617-624. (doi:10.1177/0148607113491782). (PMID:23788002).
Zanatta, A.L., Miranda, D.T., Dias, B.C., Campos, R.M., Massaro, M.C., Michelotto, P.V. Jr, West, Annette L., Miles, Elizabeth A., Calder, P.C. and Nishiyama, A. (2014) Fish oil supplementation decreases oxidative stress but does not affect platelet-activating factor bioactivity in lungs of asthmatic rats. Lipids, 49, (7), 665-675. (doi:10.1007/s11745-014-3914-7). (PMID:24858941).
Calder, Philip C. (2014) Fishing for improved outcomes in the critically ill. Critical Care Medicine, 42, (5), 1306-1307. (doi:10.1097/CCM.0000000000000197). (PMID:24736349).
Browning, L.M., Walker , C.G., Mander , A.P., West, A.L., Gambell, J., Madden , J., Calder, P.C. and Jebb, S.A. (2014) Compared with daily, weekly n-3 PUFA intake affects the incorporation of eicosapentaenoic acid and docosahexaenoic acid into platelets and mononuclear cells in humans. Journal of Nutrition, 144, (5), 667-672. (doi:10.3945/​jn.113.186346 ). (PMID:24647395).
Barros, K.V., Cassulino, A.P., Schalch, L., Munhoz , E.D., Manetta, J.A., Calder , Philip C. and Silveira, V.L. (2014) Pharmaconutrition: acute fatty acid modulation of circulating cytokines in elderly patients in the ICU. Journal of Parenteral and Enteral Nutrition, 38, (4), 467-474. (doi:10.1177/0148607113480183). (PMID:23471207).
Rossary , A., Farges , M.-C., Lamas, B., Miles, Elizabeth A., Noakes , Paul S., Kremmyda, L.-S., Vlachava, M., Diaper, N., Robinson, S.M., Godfrey, Keith M., Calder , Philip C. and Vasson, M.-P. (2014) Increased consumption of salmon during pregnancy partly prevents the decline of some plasma essential amino acid concentrations in pregnant women. Clinical Nutrition, 33, (2), 267-273. (doi:10.1016/j.clnu.2013.04.013). (PMID:23684555).
Yates , C.M., Calder, P.C. and Rainger , G.E. (2014) Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease. Pharmacology & Therapeutics, 141, (3), 272-282. (doi:10.1016/j.pharmthera.2013.10.010). (PMID:24201219).
Calder , P.C. and Deckelbaum, R.J. (2014) Editorial. Dietary fatty acids in health and disease: greater controversy, greater interest. Current Opinion in Clinical Nutrition and Metabolic Care, 17, (2), 111-115. (doi:10.1097/MCO.0000000000000038). (PMID:24448268).
Urwin, H.J., Miles, E.A., Noakes, P.S., Kremmyda , L.S., Vlachava, M., Diaper , N.D., Godfrey, K.M. and Calder , P.C. (2014) Effect of salmon consumption during pregnancy on maternal and infant faecal microbiota, secretory IgA and calprotectin. British Journal Of Nutrition, 111, (5), 773-784. (doi:10.1017/S0007114513003097). (PMID:24128654).
Scorletti, E., Bhatia , L., McCormick, K., Clough, G.F., Nash, K., Calder, P.C. and Byrne , C.D. WELCOME Trial Investigators (2014) Design and rationale of the WELCOME trial: a randomised, placebo controlled study to test the efficacy of purified long chain omega-3 fatty treatment in non-alcoholic fatty liver disease. Contemporary Clinical Trials, 37, (2), 301-311. (doi:10.1016/j.cct.2014.02.002). (PMID:24556343).
Christensen, David R., Calder, Philip C. and Houghton, Franchesca D. (2014) Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells. Cellular Physiology and Biochemistry, 33, (1), 237-246. (doi:10.1159/000356665).
Walker, C.G., Browning, L.M., Mander, A.P., Madden, J., West, A.L., Calder, P.C. and Jebb, S.A. (2014) Age and sex differences in the incorporation of EPA and DHA into plasma fractions, cells and adipose tissue in humans. British Journal Of Nutrition, 111, (4), 679-689. (doi:10.1017/S0007114513002985). (PMID:24063767).
Calder , Philip C. (2014) Limited impact of omega-3 fatty acids in patients with multiple cardiovascular risk factors. Evidence-Based Medicine, 19, (1), 18. (doi:10.1136/eb-2013-101440). (PMID:23935081).
Pearl, D.S., Masoodi, M., Eiden , M., Brümmer, J., Gullick, D., McKeever , T.M., Whittaker, M.A., Nitch-Smith, H., Brown, J.F., Shute, J.K., Mills , G., Calder , P.C. and Trebble, T. (2014) Altered colonic mucosal availability of n-3 and n-6 polyunsaturated fatty acids in ulcerative colitis and the relationship to disease activity. Journal of Crohn's and Colitis, 8, (1), 70-79. (doi:10.1016/j.crohns.2013.03.013). (PMID:23619007).
Sorensen , L.S., Thorlacius-Ussing, O., Schmidt , E.B., Rasmussen, H.H., Lundbye-Christensen, S., Calder, P.C. and Lindorff-Larsen, K. (2014) Randomized clinical trial of perioperative omega-3 fatty acid supplements in elective colorectal cancer surgery. British Journal of Surgery, 101, (2), 33-42. (doi:10.1002/bjs.9361). (PMID:24281905).
Calder, Philip C. (2014) Metabolic benefits of marine n-3 fatty acids demonstrated in nonhuman primates. Journal of Nutrition, 144, (1), 1-2. (doi:10.3945/jn.113.186999). (PMID:24198308).
Fisk , H.L., West, Annette L., Childs, C.E., Burdge, Graham C. and Calder, P.C. (2014) The use of gas chromatography to analyze compositional changes of fatty acids in rat liver tissue during pregnancy. Journal of Visualized Experiments, 85, e51445. (doi:10.3791/51445).
Miles, Elizabeth A. and Calder , Philip C. (2014) Omega-6 and omega-3 polyunsaturated Fatty acids and allergic diseases in infancy and childhood. Current Pharmaceutical Design, 20, (6), 946-953. (doi:10.2174/138161282006140220125732). (PMID:23701554).
Barros, K.V., Carvalho, P.O., Cassulino, A.P., Andrade, I., West, Annette L., Miles, Elizabeth A., Calder, P.C. and Silveira, V.L. (2013) Fatty acids in plasma, white and red blood cells, and tissues after oral or intravenous administration of fish oil in rats. Clinical Nutrition, 32, (6), 993-998. (doi:10.1016/j.clnu.2013.02.010). (PMID:23541913).
Masoodi, Mojgan, Pearl, Daniel S., Eiden, Michael, Shute, Janis K., Brown, James F., Calder, Philip C. and Trebble, Timothy M. (2013) Altered colonic mucosal polyunsaturated fatty acid (PUFA) derived lipid mediators in ulcerative colitis: new insight into relationship with disease activity and pathophysiology. PLoS ONE, 8, (10), e76532. (doi:10.1371/journal.pone.0076532). (PMID:24204637).
Burdge, Graham C. and Calder, P.C. (2013) Does early n-3 fatty acid exposure alter DNA methylation in the developing human immune system? Clinical Lipidology, 8, (5), 505-508. (doi:10.2217/clp.13.53).
Yusof , H., Cawood, A., Ding, R., Williams, J., Napper, F., Shearman, C.P., Grimble, R.F., Payne, S. and Calder, P.C. (2013) Limited impact of 2 g/day omega-3 fatty acid ethyl esters (Omacor®) on plasma lipids and inflammatory markers in patients awaiting carotid endarterectomy. Marine Drugs, 11, (9), 3569-3581. (doi:10.3390/md11093569). (PMID:24065166).
Calder, Philip C. (2013) n-3 Fatty acids, inflammation and immunity: new mechanisms to explain old actions. Proceedings of The Nutrition Society, 72, (3), 326-336. (doi:10.1017/S0029665113001031). (PMID:23668691).
Calder, Philip C. (2013) Feeding the immune system. Proceedings of The Nutrition Society, 72, (3), 299-309. (doi:10.1017/S0029665113001286). (PMID:23688939).
Calder , Philip C. (2013) Lipids for intravenous nutrition in hospitalised adult patients: a multiple choice of options. Proceedings of The Nutrition Society, 72, (3 ), 263-276. (doi:10.1017/S0029665113001250). (PMID:23663322).
Zhang, Jian, Wang, Chunrong, Gao, Yixiong, Li , Lixiang, Man , Qingqing, Song, Pengkun, Meng, Liping, Du, Zhen-Yu, Miles, Elizabeth A., Lie, Øvyind, Calder, Philip C. and Frøyland, Livar (2013) Different intakes of n-3 fatty acids among pregnant women in 3 regions of China with contrasting dietary patterns are reflected in maternal but not in umbilical erythrocyte phosphatidylcholine fatty acid composition. Nutrition Research, 33, (8), 613-621. (doi:10.1016/j.nutres.2013.05.009). (PMID:23890350).
Albers, R., Bourdet-Sicard, R., Braun, D., Calder, P.C., Herz, U., Lambert, C., Lenoir-Wijnkoop, I. and Méheust, A. (2013) Monitoring immune modulation by nutrition in the general population: identifying and substantiating effects on human health. British Journal Of Nutrition, 110, supplement 2, S1-S30. (doi:10.1017/S0007114513001505). (PMID:23902657).
Barros , Karina V., Cassulino , Ana Paula, Schalch, Lívia, Della Valle Munhoz , Eduardo, Manetta, José Antonio, Noakes , Paul S., Miles, Elizabeth A., Calder , Philip C. and Flor Silveira, Vera L. (2013) Supplemental intravenous n-3 fatty acids and n-3 fatty acid status and outcome in critically ill elderly patients in the ICU receiving enteral nutrition. Clinical Nutrition, 32, (4), 599-605. (doi:10.1016/j.clnu.2012.10.016). (PMID:23260750).
Kagan, Michael L., West, Annette L., Zante , Christa and Calder, Philip C. (2013) Acute appearance of fatty acids in human plasma -- a comparative study between polar-lipid rich oil from the microalgae Nannochloropsis oculata and krill oil in healthy young males. Lipids in Health and Disease, 12, (1) (doi:10.1186/1476-511X-12-102). (PMID:23855409).
Calder , Philip C. (2013) Fishing for allergy prevention. Clinical and Experimental Allergy, 43, (7), 700-702. (doi:10.1111/cea.12126). (PMID:23786275).
Hoile, Samuel P., Irvine, Nicola A., Kelsall, Christopher J., Sibbons, Charlene, Feunteun, Aurelie, Collister, Alex, Torrens, Christopher, Calder, P.C., Hanson, Mark A., Lillycrop, Karen A. and Burdge, Graham C. (2013) Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. Journal of Nutritional Biochemistry, 24, (7), 1213-1220. (doi:10.1016/j.jnutbio.2012.09.005). (PMID:23107313).
Calder, Philip C. (2013) Long chain fatty acids and gene expression in inflammation and immunity. Current Opinion in Clinical Nutrition and Metabolic Care, 16, (4), 425-433. (doi:10.1097/MCO.0b013e3283620616). (PMID:23657154).
Nunes, E., Gonçalves-Neto, L., Ferreira, F., Dos Santos, C., Fernandes, L., Boschero, A., Calder, Philip C. and Rafacho, A. (2013) Glucose intolerance induced by glucocorticoid excess is further impaired by co-administration with β-hydroxy-β-methylbutyrate in rats. Applied Physiology Nutrition and Metabolism, 38, (11), 1137-1146. (doi:10.1139/apnm-2012-0456). (PMID:24053521).
Miranda, D.T., Zanatta, A.L., Dias, B.C., Fogaça, R.T., Maurer, J.B., Donatti, L., Calder, Philip C. and Nishiyama, A. (2013) The effectiveness of fish oil supplementation in asthmatic rats is limited by an inefficient action on ASM function. Lipids, 48, (9), 889-897. (doi:10.1007/s11745-013-3804-4). (PMID:23743575).
Urwin, Heidi, Zhang, Jian, Gao, Yixong, Wang, Chunrong, Li, Lixiang, Song, Pengkun, Man , Qingqing, Meng, Lipeng, Frøyland, Livar, Miles, Elizabeth A., Calder, Philip C. and Yaqoob, Parveen (2013) Immune factors and fatty acid composition in human milk from river/lake, coastal and inland regions of China. British Journal Of Nutrition, 109, (11), 1949-1961. (doi:10.1017/S0007114512004084). (PMID:23148871).
Al-Taan, Omer, Stephenson, James A., Spencer, Laura, Pollard, Cristina, West, Annette L., Calder, P.C., Metcalfe, Matthew and Dennison, Ashley R. (2013) Changes in plasma and erythrocyte omega-6 and omega-3 fatty acids in response to intravenous supply of omega-3 fatty acids in patients with hepatic colorectal metastases. Lipids in Health and Disease, 12, (64) (doi:10.1186/1476-511X-12-64). (PMID:23648075).
Stephenson, James A., Al-Taan, Omer, Arshad, Ali, West, Annette L., Calder, Philip C., Morgan, Bruno, Metcalfe, Matthew S. and Dennison, Ashely R. (2013) Unsaturated fatty acids differ between hepatic colorectal metastases and liver tissue without tumour in humans: results from a randomised controlled trial of intravenous eicosapentaenoic and docosahexaenoic acids. Prostaglandins Leukotrienes and Essential Fatty Acids, 88, (6), 405-410. (doi:10.1016/j.plefa.2013.04.002). (PMID:23647811).
Turnock, Amy, Calder, Philip C., West, Annette L., Izzard, Mark, Morton, Randall P. and Plank, Lindsay D. (2013) Perioperative immunonutrition in well-nourished patients undergoing surgery for head and neck cancer: evaluation of inflammatory and immunologic outcomes. Nutrients, 5, (4), 1186-1199. (doi:10.3390/nu5041186). (PMID:23571650).
Borel, P., Lietz, G., Goncalves, A., Szabo de Edelenyi, F., Lecompte , S., Curtis, P., Goumidi , L., Caslake, M.J., Miles, Elizabeth A., Packard, C., Calder, P.C., Mathers, J.C ., Minihane, A.M., Tourniaire, F., Kesse-Guyot , E., Galan, P., Hercberg, S., Breidenassel , C., González Gross, M., Moussa, M., Meirhaeghe, A. and Reboul, E. (2013) CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK Cells, and some of their genetic variants are associated with plasma concentrations of these micronutrients in humans. Journal of Nutrition, 143, (4), 448-456. (doi:10.3945/​jn.112.172734 ). (PMID:23427331).
Calder, P.C. (2013) Editorial: fat chance to enhance B cell function. Journal of Leukocyte Biology, 93, (4), 457-459. (doi:10.1189/jlb.1212646 ). (PMID:23547174).
Calder, Philip C. and Deckelbaum, Richard J. (2013) Intravenous fish oil in hospitalized adult patients: reviewing the reviews. Current Opinion in Clinical Nutrition and Metabolic Care, 16, (2), 119-123. (doi:10.1097/MCO.0b013e32835dbde9). (PMID:23324901).
Calder, P.C. (2013) Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? British Journal of Clinical Pharmacology, 75, (3), 645-662. (doi:10.1111/j.1365-2125.2012.04374.x). (PMID:22765297).
Walker, C.G., Jebb, S.A. and Calder, Philip C. (2013) Stearidonic acid as a supplemental source of ω-3 polyunsaturated fatty acids to enhance status for improved human health. Nutrition, 29, (2), 363-369. (doi:10.1016/j.nut.2012.06.003). (PMID:23102888).
Moon, R. J., Harvey, N. C., Robinson, S. M., Ntani, G., Davies, J. H., Inskip, H. M., Godfrey, K. M., Dennison, E. M., Calder, P. C., Cooper, C. and SWS Study Group (2013) Maternal plasma polyunsaturated fatty acid status in late pregnancy is associated with offspring body composition in childhood. Journal of Clinical Endocrinology & Metabolism, 98, (1), 299-307. (doi:10.1210/jc.2012-2482). (PMID:23162098).
Calder , Philip C., Ahluwalia, N., Albers, R., Bosco, N., Bourdet-Sicard, R., Haller, D., Holgate, S., Jonsson, L., Latulippe, M., Marcos, A., Moreines, J., M’Rini, C., Muller, M., Pawelec, G., van Neerven, R., Watzl, B. and Zhao, J. (2013) A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies. British Journal of Nutrition, 109, supplement 1, S1-S34. (doi:10.1017/S0007114512005119). (PMID:23343744).
Calder , Philip C. (2013) Omega-3 fatty acids in health and disease: the science behind the headlines. NHD Magazine, 83, 18-19.
Calder , P.C. (2012) Parenteral omega-3 fatty acids: pouring oil on troubled waters? Critical Care, 16, (6), 172. (PMID:23146333).
Lomax, Amy R., Cheung, Lydia V.Y., Tuohy, Kieran M., Noakes, Paul S., Miles, Elizabeth A. and Calder, Philip C. (2012) β2-1 Fructans have a bifidogenic effect in healthy middle-aged human subjects but do not alter immune responses examined in the absence of an in vivo immune challenge: results from a randomised controlled trial. British Journal Of Nutrition, 108, (10), 1818-1828. (doi:10.1017/S0007114511007276). (PMID:22244014).
Browning, Lucy M., Walker, Celia G., Mander, Adrian P., West , Annette L., Madden, Jackie, Gambell , Joanna M., Young , Stephen, Wang, Laura, Jebb, Susan A. and Calder, Philip C. (2012) Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish. American Journal of Clinical Nutrition, 96, (4), 748-758. (doi:10.3945/ajcn.112.041343). (PMID:22932281).
Harvey, N., Dhanwal, D., Robinson, S., Kim, M., Inskip, H., Godfrey, K., Dennison, E., Calder, P., Cooper, C. and SWS Study Group (2012) Does maternal long chain polyunsaturated fatty acid status in pregnancy influence the bone health of children? Osteoporosis International, 23, (9), 2359-2367. (doi:10.1007/s00198-011-1860-2). (PMID:22159749).
Urwin , Heidi J., Miles, Elizabeth A., Noakes , Paul S., Kremmyda , Lefkothea-Stella, Vlachava, Maria, Diaper , Norma D., Pérez-Cano, Francisco J., Godfrey, Keith M., Calder, Philip C. and Yaqoob , Parveen (2012) Salmon consumption during pregnancy alters fatty acid composition and secretory IgA concentration in human breast milk. Journal of Nutrition, 142, (8), 1603-1610. (doi:10.3945/jn.112.160804). (PMID:22739373).
Magdalon, Juliana, Vinolo , Mario A. R., Rodrigues, Hosana G., Paschoal, Vivian A., Torres, Rosângela P., Mancini-Filho, Jorge, Calder, Philip C., Hatanaka, Elaine and Curi, Rui (2012) Oral administration of oleic or linoleic acids modulates the production of inflammatory mediators by rat macrophages. Lipids, 47, (8), 803-812. (doi:10.1007/s11745-012-3687-9). (PMID:22695743).
Calder, P.C. (2012) Feeding the immune system. Public Service Review: UK Science & Technology, 6, 50-51.
García-Rodríguez, C.E., Olza, J., Aguilera, C.M., Mesa, M.D., Miles, E.A., Noakes, Paul S., Vlachava, M., Kremmyda , L.S., Diaper, N.D., Godfrey, Keith M., Calder, P.C. and Gil, A (2012) Plasma inflammatory and vascular homeostasis biomarkers increase during human pregnancy but are not affected by oily fish intake. Journal of Nutrition, 142, (7), 1191-1196. (doi:10.3945/​jn.112.158139 ). (PMID:22623389).
Calder , Philip C. (2012) The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability. Molecular Nutrition & Food Research, 56, (7), 1073-1080. (doi:10.1002/mnfr.201100710). (PMID:22760980).
Calder, P.C. and Yaqoob, P. (2012) Marine omega-3 fatty acids and coronary heart disease. Current Opinion in Cardiology, 27, (4), 412-419. (doi:10.1097/HCO.0b013e328353febd). (PMID:22565141).
Koletzko, B., Szajewska , H., Ashwell, M., Shamir, R., Aggett, P., Baerlocher, K, Noakes, P.S., Braegger, C., Calder, P.C., Campoy Folgoso, C., Colomb, V., Decsi, T., Domellöf, M., Dupont, C., Fewtrell, M., van Goudoever, J.B., Michaelsen, K.F., Mihatsch, W., Guarino, A., Koletzko, S., Rigo, J., Turck, D. and Taminiau, J. (2012) Documentation of functional and clinical effects of infant nutrition: setting the scene for COMMENT. Annals of Nutrition and Metabolism, 60, (4), 222-232. (doi:10.1159/000337681). (PMID:22677876).
Gil, A., Serra-Majem, L., Calder, P.C. and Uauy, R. (2012) Systematic reviews of the role of omega-3 fatty acids in the prevention and treatment of disease. British Journal Of Nutrition, 107, (2), S1-S2. (PMID:22591884).
Calder, P.C. (2012) Editorial. BJN gets a new sister! British Journal Of Nutrition, 107, (11), 1561. (doi:10.1017/S0007114512000244). (PMID:22321289).
Fuller, Richard, Butt, Hamza, Noakes, Paul S., Kenyon, Julian, Yam, Tat Shing and Calder, Philip C. (2012) Influence of yeast-derived 1,3/1,6 glucopolysaccharide on circulating cytokines and chemokines with respect to upper respiratory tract infections. Nutrition, 28, (6), 665-669. (doi:10.1016/j.nut.2011.11.012). (PMID:22465901).
England, Anna, Valdes, Ana M., Slater-Jefferies, Joanne L., Gill, Rosalynn, Howell, W. Martin, Calder, Philip C. and Grimble, Robert F. (2012) Variants in the genes encoding TNF-α, IL-10, and GSTP1 influence the effect of a-tocopherol on inflammatory cell responses in healthy men. American Journal of Clinical Nutrition, 95, (6), 1461-1467. (doi:10.3945/ajcn.111.012781). (PMID:22572643).
Calder , Philip C. (2012) Long-chain fatty acids and inflammation. Proceedings of The Nutrition Society, 71, (2), 284-289. (doi:10.1017/S0029665112000067 ). (PMID:22369781).
Bhatia, L.S., Curzen, N., Calder, P.C. and Byrne, Christopher D. (2012) Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor. European Heart Journal, 33, (10), 1190-200. (PMID:22408036).
García-Rodríguez, Cruz E., Mesa, Maria D. and Olza, Josune et al. (2012) Does consumption of two portions of salmon per week enhance the antioxidant defense system in pregnant women? Antioxidants & Redox Signaling, 16, (12), 1401-1406. (doi:10.1089/ars.2012.4508). (PMID:22229304).
Kelsall, Christopher J., Hoile, Samuel P., Irvine, Nicola A., Masoodi, Mojgan, Torrens, Christopher, Lillycrop, Karen A., Calder, Philip C., Clough, Geraldine F., Hanson, Mark A. and Burdge, Graham C. (2012) Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis. PLoS ONE, 7, (4), e34492. (doi:10.1371/journal.pone.0034492). (PMID:22509311).
Kofler , B.M., Miles, Elizabeth A., Curtis , P., Armah, C.K., Tricon, S., Grew, J., Napper, F.L., Farrell , L., Lietz, G., Packard, C.J., Caslake, M.J., Mathers, J.C., Williams, C.M., Calder, P.C. and Minihane, A.M. (2012) Apolipoprotein E genotype and the cardiovascular disease risk phenotype: impact of sex and adiposity (the FINGEN study). Atherosclerosis, 221, (2), 467-470. (doi:10.1016/j.atherosclerosis.2012.01.042). (PMID:22365656).
Calder, P. C. (2012) The Nutrition Society fully engages with the Open Access model of publishing. Journal of Nutritional Science, 1, (e1) (doi:10.1017/jns.2012.1).
Bonatto , S.J., Oliveira, H.H., Nunes, E.A., Pequito, D., Lagher, F., Coelho, I., Naliwaiko, K., Kryczyk, M., Brito, G.A., Repka, J., Sabóia, L.V., Fukujima, G., Calder, P.C. and Fernandes, L.C. (2012) Fish oil supplementation improves neutrophil function during cancer chemotherapy. Lipids, 47, (4), 383-389. (doi:10.1007/s11745-011-3643-0). (PMID:22160495).
Rizzardini, Giuliano, Eskesen, Dorte, Calder , Philip C., Capetti, Amedeo, Jespersen , Lillian and Clerici, Mario (2012) Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12® and Lactobacillus paracasei ssp. paracasei, L. casei 431® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study. British Journal of Nutrition, 107, (6), 876-884. (doi:10.1017/S000711451100420X ). (PMID:21899798).
Aggett , P.J., Hathcock, J., Jukes, D., Richardson, D.P., Calder, P.C., Bischoff-Ferrari, H., Nicklas, T., Mühlebach, S., Kwon, O., Lewis, J., Lugard, M.J. and Prock, P. (2012) Nutrition issues in Codex: health claims, nutrient reference values and WTO agreements: a conference report. European Journal of Nutrition, 51, supplement 1, 1-7. (doi:10.1007/s00394-012-0306-8). (PMID:22350923).
Dichi, I., Simao, A.N., Vannucchi, H., Curi, R. and Calder, P.C. (2012) Editorial. Metabolic syndrome: epidemiology, pathophysiology, and nutrition intervention. Journal of Nutrition and Metabolism, (584541) (doi:10.1155/2012/584541). (PMID:22778922).
Versleijen, Michelle W., Roelofs, Hennie M., Rombouts, Charlotte, Hermans, Peter W., Noakes, Paul S., Calder , Philip C. and Wanten, Geert J. (2012) Short-term infusion of a fish oil-based lipid emulsion modulates fatty acid status, but not immune function or (anti)oxidant balance: a randomized cross-over study. European Journal of Clinical Investigation, 42, (3), 290-302. (doi:10.1111/j.1365-2362.2011.02582.x). (PMID:21880037).
Deckelbaum, Richard J. and Calder, Philip C. (2012) Different outcomes for omega-3 heart trials: why? Current Opinion in Clinical Nutrition and Metabolic Care, 15, (2), 97-98. (doi:10.1097/MCO.0b013e32834ec9e5). (PMID:22186355).
Noakes, P.S., Vlachava, M., Kremmyda, L.S., Diaper, N.D., Miles, E.A., Erlewyn-Lajeunesse, M., Williams, A.P., Godfrey, K.M. and Calder, P.C. (2012) Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 months. American Journal Clinical Nutrition, 95, (2), 395-404. (doi:10.3945/​ajcn.111.022954 ). (PMID:22218160).
Calder, Philip C. (2012) Mechanisms of action of (n-3) fatty acids. Journal of Nutrition, 142, (3), supplement Heart healthy omega-3s for food - stearidonic acid (SDA) as a sustainable choice, 592S-599S. (doi:10.3945/jn.111.155259). (PMID:22279140).
Rodrigues, Hosana G., Vinolo, Marco Aurelio, Magdalon, Juliana, Vitzel, Kaio, Nachbar, Renato T., Pessoa, Ana Flavia, dos Santos, Marinilce F., Hatanaka, Elaine, Calder, Philip C. and Curi, Rui (2012) Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing. Journal of Investigative Dermatology, 132, (1), 208-215. (doi:10.1038/jid.2011.265). (PMID:21881592).
Helmersson-Karlqvist, Johanna, Miles, Elizabeth A., Vlachava, Maria, Kremmyda, Lefkothea-Stella, Noakes , Paul S., Diaper, Norma D., Godfrey, Keith M., Calder, Philip C. and Basu, Samar (2012) Enhanced prostaglandin F2α formation in human pregnancy and the effect of increased oily fish intake: Results from the Salmon in Pregnancy Study. Prostaglandins Leukotrienes and Essential Fatty Acids, 86, (1-2), 35-38. (doi:10.1016/j.plefa.2011.10.008). (PMID:22047909).
Helmersson-Karlqvist, Johanna, Miles, Elizabeth A., Vlachava, Maria, Kremmyda, Lefkothea-Stella, Noakes , Paul S., Diaper, Norma D., Godfrey, Keith M., Calder, Philip C. and Basu, Samar (2012) Enhanced prostaglandin F(2α) formation in human pregnancy and the effect of increased oily fish intake: results from the salmon in pregnancy study. Prostaglandins Leukotrienes and Essential Fatty Acids, 86, (1-2), 35-38. (doi:10.1016/j.plefa.2011.10.008). (PMID:22047909).
Calder , Philip and Hall , Veronica (2012) Understanding gut-immune interactions in management of acute infectious diarrhoea. Nursing Older People, 24, (9), 29-37.
Pike, Katharine C., Calder, Philip C., Inskip, Hazel M., Robinson, Sian M., Roberts, Graham C., Cooper, Cyrus, Godfrey, Keith M. and Lucas, Jane S.A. (2012) Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years. Clinical and Developmental Immunology, 2012, 474613. (doi:10.1155/2012/474613). (PMID:23049600).
Calder , Philip C., Ahluwalia, Namanjeet, Brouns , Fred, Buetler, Timo, Clement, Karine, Cunningham , Karen, Esposito , Katherine, Jonsson, Lena S., Kolb, Hubert, Lansink, Mirian, Marcos, Ascension, Margioris, Andrew, Matusheski, Nathan, Nordmann, Herve, O’Brien, John, Pugliese, Giuseppe, Rizkalla, Salwa, Schalkwijk, Casper, Tuomilehto, Jaakko, Warnberg, Julia, Watzl, Bernhard and Winklhofer-Roob, Brigitte M. (2011) Dietary factors and low-grade inflammation in relation to overweight and obesity. British Journal Of Nutrition, 106, supplement 3, S1-S78. (doi:10.1017/S0007114511005460). (PMID:22133051).
Scorletti , E., Calder, P. C. and Byrne, C. D. (2011) Non-alcoholic fatty liver disease and cardiovascular risk: metabolic aspects and novel treatments. Endocrine, 40, (3), 332-343. (doi:10.1007/s12020-011-9530-x). (PMID:21894514).
van den Elsen, L.W., Noakes, P.S., van der Maarel, M.A., Kremmyda, L.S., Vlachava, M., Diaper, N.D., Miles, E.A., Eussen, S.R., Garssen, J., Willemsen, L.E., Wilson, S.J., Godfrey, K.M. and Calder, P.C. (2011) Salmon consumption by pregnant women reduces ex vivo umbilical cord endothelial cell activation. American Journal of Clinical Nutrition, 94, (6), 1418-1425. (doi:10.3945/​ajcn.111.016592 ). (PMID:22011457).
Garcia-Rodriguez, Cruz E., Helmersson-Karlqvist, Johanna, Mesa, Maria Dolores, Miles, Elizabeth A., Noakes , Paul S., Vlachava, Maria, Kremmyda, Lefkothea-Stella, Diaper, Norma D., Godfrey, Keith M., Calder, Philip C., Gil, Ángel and Basu, Samar (2011) Does increased intake of salmon increase markers of of oxidative stress in pregnant women? Antioxidants & Redox Signaling, 15, (11), 2819-2823. (doi:10.1089/ars.2011.4108). (PMID:21689025).
Yates , Clara M., Calder , Philip C. and Rainger , G. Ed (2011) Omega-3 polyunsaturated fatty acids and cardiovascular disease. Bulletin of the British Society for Cardiovascular Research, 24, (4), 4-11.
Calder , Philip C. (2011) Fatty acids and inflammation: the cutting edge between food and pharma. European Journal of Pharmacology, 668, supplement 1, S50-S58. (doi:10.1016/j.ejphar.2011.05.085). (PMID:21816146).
Madden, Jacqueline, Williams, C.M., Calder, P.C., Lietz, G., Miles, Elizabeth A., Cordell, H., Mathers, J.C. and Minihane, A.M. (2011) The impact of common gene variants on the response of biomarkers of cardiovascular disease (CVD) risk to increased fish oil fatty acids intakes. Annual Review of Nutrition, 31, 203-234. (doi:10.1146/annurev-nutr-010411-095239). (PMID:21568708).
Miles, E.A., Noakes, P.S., Kremmyda, L.S., Vlachava, M., Diaper, N.D., Rosenlund, G., Urwin, H., Yaqoob, P., Rossary, A., Farges, M.C., Vasson, M.P., Liaset, B., Froyland, L., Helmersson, J., Basu, S., Garcia, E., Olza, J., Mesa, M.D., Aguilera, C.M., Gil, A., Robinson, S.M., Inskip, H.M., Godfrey, K.M. and Calder, P.C. (2011) The salmon in pregnancy study: study design, subject characteristics, maternal fish and marine n-3 fatty acid intake, and marine n-3 fatty acid status in maternal and umbilical cord blood. American Journal of Nutrition, 94, supplement 6, 1986S-1992S. (doi:10.3945/​ajcn.110.001636). (PMID:21849598).
Calder, Philip C. (2011) More citations, but a fall in impact factor. British Journal Of Nutrition, 106, (6), 789-792. (doi:10.1017/S0007114511004193). (PMID:21787452).
Yates, Clara M., Tull , Samantha P., Madden, Jackie, Calder, Philip C., Grimble, Robert F., Nash, Gerard B. and Rainger, G. Ed (2011) Docosahexaenoic acid inhibits the adhesion of flowing neutrophils to cytokine stimulated human umbilical vein endothelial cells. Journal of Nutrition, 141, (7), 1331-1334. (doi:10.3945/jn.111.139287). (PMID:21613456).
Garcia-Larsen, V., Luczynska, M., Kowalski, M.L., Voutilainen, H., Ahlström, M., Haahtela, T., Toskala, E., Bockelbrink, A., Lee, H-H., Vassilopoulou, E., Papadopoulos, N.G., Ramalho, R., Moreira, A., Delgado, L., Castel-Branco, M.G., Calder, P.C., Childs, C.E., Bakolis, I., Hooper, R. and Burney, P.G. (2011) Use of a common food frequency questionnaire (FFQ) to assess dietary patterns and their relation to allergy and asthma in Europe: pilot study of the GA(2)LEN FFQ. European Journal of Clinical Nutrition, 65, (6), 750-756. (doi:10.1038/ejcn.2011.15). (PMID:21427744).
Sijben, John W.C., Goedhart, Annemiek C., Kamphuis, Patrick J.G.H., Calder, Philip C., Gottrand, Frederic and Koletzko, Berthold (2011) Is it prudent to add n-3 long-chain polyunsaturated fatty acids to paediatric enteral tube feeding? Clinical Nutrition, 30, (3), 273-281. (doi:10.1016/j.clnu.2010.11.007). (PMID:21177002).
Ranchordas, M.K., Blomstrand , E., Calder, P.C., Burke, L.M., Stear, S.J. and Castell, L.M. (2011) A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 23. British Journal of Sports Medicine, 45, 830-831. (doi:10.1136/bjsports-2011-090294).
Faber, J., Berkhout, M., Vos, A.P., Sijben , J.W., Calder, P.C., Garssen, J. and van Helvoort, A. (2011) Supplementation with a fish oil-enriched, high-protein medical food leads to rapid incorporation of EPA into white blood cells and modulates immune responses within one week in healthy men and women. Journal of Nutrition, 141, (5), 964-970. (doi:10.3945/​jn.110.132985 ). (PMID:21430245).
Kogenkamp, Astrid, van Vlies, Naomi, Fear, Alison L, van Esch, Betty C., Hofman, Gerard A., Garssen, Johan and Calder, Philip C. (2011) Dietary fatty acids affect the immune system in male mice sensitized to ovalbumin or vaccinated with influenza. Journal of Nutrition, 141, 698-702. (doi:10.3945/​jn.110.135863). (PMID:21346107).
Calder, Philip C. (2011) Editors' conflicts of interest 2011. British Journal Of Nutrition, 105, (5), 661-662. (doi:10.1017/S0007114510005787).
Wanten, Geert, Calder, Philip C. and Forbes, Alastair (2011) Managing adult patients who need home parenteral nutrition. British Medical Journal, 342, 696-701. (doi:10.1136/bmj.d1447). (PMID:21421667).
Calder, Phillip C. and Deckelbaum, Richard J. (2011) Harmful, harmless or helpful? The n-6 fatty acid debate goes on. Current Opinion in Clinical Nutrition & Metabolic Care, 14, (2), 113-114. (doi:10.1097/MCO.0b013e328343d895).
Dionisi , F. and Calder, P. C. (2011) Omega 3 fatty acids for the treatment of dementia and cognitive impairment. Cochrane Database of Systematic Reviews, (2) (doi:10.1002/14651858.CD009002).
Nunes, Everson A., Lomax, A.R., Noakes, Paul, Miles, Elizabeth A., Fernandes, L.C. and Calder, P.C. (2011) Beta-hydroxy-beta-methylbutyrate modifies human peripheral blood mononuclear cell proliferation and cytokine production in vitro. Nutrition, 27, (1), 92-99. (doi:10.1016/j.nut.2009.12.008 ). (PMID:20541366).
Nunes, Everson A., Lomax , Amy R., Noakes , Paul S., Miles, Elizabeth A., Fernandes, Luiz C. and Calder, Phillip C. (2011) β-Hydroxy-β-methylbutyrate modifies human peripheral blood mononuclear cell prliferation and cytokine production in vitro. Nutrition, 27, (1), 92-99. (doi:10.1016/j.nut.2009.12.008).
Kremmyda, Lefkothea-Stella, Vlachava, Maria, Noakes, Paul, Diaper, Norma D., Miles, Elizabeth A. and Calder, Philip C. (2011) Atopy risk in infants and children in relation to early exposure to fish, oily fish, or long-chain omega-3 fatty acids: a systematic review. Clinical Reviews in Allergy & Immunology, 41, (1), 36-66.
Sala-Vila, Aleix and Calder , Philip C. (2011) Update on the relationship of fish intake with prostate, breast, and colorectal cancers. Critical Reviews in Food Science and Nutrition, 51, (9), 855-871. (doi:10.1080/10408398.2010.483527). (PMID:21888535).
van vlies, N., Hogenkamp, A., Fear, A.L, van Esch, B.C., Oosting, A., van de Heijning, B., van der Beek, E., Calder, P.C. and Garssen, J. (2011) Perinatal programming of murine immune responses by polyunsaturated fatty acids. Journal of Developmental Origins of Health and Disease, 2, (2), 112-123. (doi:10.1017/S204017441000067X).
Miles, E.A., Noakes, Paul S., Kremmyda, L.S., Vlachava, M., Diaper, N.D., Rosenlund, G., Urwin, H., Yaqoob, P., Rossary, A., Farges, M.C., Vasson, M.P., Liaset, B., Froyland, L., Helmersson, J., Basu, S., Garcia, E., Olza, J., Mesa, M.D., Aguilera, C.M., Gil, A., Robinson, S.M., Inskip, Hazel M., Godfrey, Keith M. and Calder, P.C. (2011) The Salmon in Pregnancy Study: study design, subject characteristics, maternal fish and marine n-3 fatty acid intake, and marine n-3 fatty acid status in maternal and umbilical cord blood. American Journal of Clinical Nutrition, 94, supplement 6, 1986S-1992S. (doi:10.3945/ajcn.110.001636).
Belo, Sérgio R.B., Lagher , Fabíola, Bonatto, Sandro J., Naliwaiko, Katya, Calder, Philip C., Nunes, Everson A. and Fernandes, Luiz C. (2010) Walker-256 tumor growth is inhibited by the independent or associative chronic ingestion of shark liver and fish oil: a response linked by the increment of peritoneal macrophages nitrite production in Wistar rats. Nutrition Research, 30, (11), 770-776. (doi:10.1016/j.nutres.2010.09.015).
Childs, Caroline E., Romijn, Tessa, Enke, Ute, Hoile, Samuel P. and Calder, Philip C. (2010) Maternal diet during pregnancy has tissue-specific effects upon fetal fatty acid composition and alters fetal immune parameters. Prostaglandins Leukotrienes and Essential Fatty Acids, 83, (4), 179-183. (doi:10.1016/j.plefa.2010.08.007). (PMID:20817424).
Calder, Philip C. (2010) Guest editorial. ISSFAL comes of age. Prostaglandins, Leukotrienes and Essential Fatty Acids, 83, (4-6), 177-178. (doi:10.1016/j.plefa.2010.08.008).
Calder, P.C., Lindley, M.R., Burke, L.M., Stear, S.J. and Castell, L.M. (2010) A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance Part 14. British Journal of Sports Medicine, 44, (14), 1065-1067. (doi:10.1136/bjsm.2010.079525). (PMID:21041244).
Rodrigues, Hosana Gomes, Vinolo, Marco Aurelio, Magdalon, Juliana, Fujiwara, Harolodo, Cavalcanti, Danielle M., Farsky, Sandra H. P., Calder, Philip C., Hatanaka, Elaine and Curi, Rui (2010) Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. Lipids, 45, (9), 809-819. (doi:10.1007/s11745-010-3461-9). (PMID:20730605).
Cawood, Abbie L., Ding, Ren, Napper, Frances L., Young, Ruth H., Williams, Jennifer A., Ward, Matthew J.A., Gudmundsen, Ola, Vige, Runar, Payne, Simon P.K., Ye, Shu, Shearman, Cliff P., Gallagher, Patrick J., Grimble, Robert F. and Calder, P.C. (2010) Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability. Atherosclerosis, 212, (1), 252-259. (doi:10.1016/j.atherosclerosis.2010.05.022). (PMID:20542512).
Calder, P.C., Kremmyda, L.S., Vlachava, M, Noakes, Paul and Miles, Elizabeth A. (2010) Is there a role for fatty acids in early life programming of the immune system? Proceedings of The Nutrition Society, 69, (3), 373-380. (doi:10.1017/S0029665110001552). (PMID:20462467).
Saravan, Palaniappan, Davidson, Neil C., Schmidt, Erik B. and Calder, Philip C. (2010) Cardiovascular effects of marine omega-3 fatty acids. The Lancet, 376, (9740), 540-550. (doi:10.1016/S0140-6736(10)60445-X). (PMID:20638121).
Calder, Philip C. (2010) BJN impact factor rises by 25%. British Journal Of Nutrition, 104, 621-623. (doi:10.1017/S0007114509991619).
Stear, S.J., Castell, L.M, Burke, L.M., Jeacocke, N., Ekblom B., B., Shing, C., Calder, P.C. and Lewis, N. (2010) A-Z of nutritional suppliments: dietary supplements, sports nutrition foods and ergogenic aids for health and performance-part 10. British Journal of Sports Medicine, 44, (9), 688-690. (doi:10.1136/bjsm.2010.075218).
Calder, Philip C. (2010) Does early exposure to long chain polyunsaturated fatty acids provide immune benefits? Journal of Pediatrics, 156, (6), 869-871. (doi:10.1016/j.jpeds.2010.03.024). (PMID:20434731).
Calder, Phillip C. (2010) Rationale and use of n-3 fatty acids in artificial nutrition. Proceedings of The Nutrition Society, 69, (4), 565-573. (doi:10.1017/S0029665110000157). (PMID:20441676).
Calder, Philip C. (2010) Is the demographic of British journal of Nutrition authors changing? British Journal of Nutrition, 103, (10), 1389-1390. (doi:10.1017/S0007114510001959 ). (PMID:20470450).
Calder, Phillip C., Jensen, Gordon L., Koletzko, Berthold V., Singer, Pierre and Wanten, Geert J.A. (2010) Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions. Intensive Care Medicine, 36, (5), 735-749. (doi:10.1007/s00134-009-1744-5). (PMID:20072779).
Rerkasem, Kittipan, Gallagher, Patrick J., Grimble, Robert F., Calder, Philip C. and Shearman, Clifford P. (2010) Sex difference in composition of plaques of patients undergoing carotid endarterectomy. Vascular, 18, (2), 77-81. (doi:10.2310/6670.2010.00008). (PMID:20338131).
Calder, Philip C. (2010) The Ninth Fatty Acids and Cell Signalling meeting (FACS-09). Prostaglandins, Leukotrienes and Essential Fatty Acids, 82, (4-6), 147. (doi:10.1016/j.plefa.2010.02.027).
Calder, Philip C. (2010) A novel effect of eicosapentaenoic acid: improved diaphragm strength in endotoxemia. Critical Care, 14, (2), 143. (doi:10.1186/cc8951). (PMID:20429961).
Peacock, Emma, Stanley, John, Calder, Phillip C., Jebb, Susan A., Thies, Frank, Seal, Chris J, Woodside, Jayne V. and Sanders, Tom A.B. (2010) UK Food Standards Agency workshops report: carbohydrate and cardiovascular risk. British Journal Of Nutrition, 103, (11), 1688-1694. (doi:10.1017/S0007114510000735).
Sanderson, Peter, Elsom, Rachel L., Kirkpatrick, Verity, Calder, Phillip C., Woodside, Jayne V., Williams, Elizabeth A., Rink, Lothar, Fairweather-Tait, Susan, Ivory, Kamal, Cantorna, Margherita, Waltzl, Bernhard and Stone, Elaine M. (2010) UK Food Standards Agency workshop report: diet and immune function. British Journal Of Nutrition, 103, (11), 1684-1687. (doi:10.1017/S0007114509993692). (PMID:20211037).
Calder, Philip C. (2010) Omega-3 fatty acids and inflammatory processes. Nutrients, 2, (3), 355-374. (doi:10.3390/nu2030355).
Calder, P.C. and Yaqoob, P. (2010) Omega-3 (n-3) fatty acids, cardiovascular disease and stability of atherosclerotic plaques. Cellular and Molecular Biology, 56, (1), 28-37.
Saravanan, Palanaippan, Bridgewater, Ben, West, Annette L., O'Neill, Stephen C., Calder, Philip C. and Davidson, Neil C. (2010) Omega-3 fatty acid supplementation does not reduce risk of atrial fibrillation after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trial. Circulation Arrhythmia and Electrophysiology, 3, 46-53. (doi:10.1161/CIRCEP.109.899633).
Barbosa, Vera M., Miles, Elizabeth A., Calhau, Conceiao, Lafuente, Estevao and Calder, Phillip C. (2010) Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Critical Care, 14, (1), 1-29. (doi:10.1186/cc8844).
Deckelbaum, Richard J and Calder, Philip C. (2010) Dietary n-3 and n-6 fatty acids: are there 'bad' polysaturated fatty acids? Current Opinion in Clinical Nutrition and Metabolic Care, 13, (2), 123-124. (doi:10.1097/MCO.0b013e328336696d ).
Calder, P.C. (2010) The Americal Heart Association advisory on n-6 fatty acids: evidence based on biased evidence? British Journal Of Nutrition, 104, (11), 1575-1576. (doi:10.1017/S0007114510004253). (PMID:21118616).
Calder, Philip C. (2010) Omega-3 fatty acids from fish and plants: same family different biological activity. Nutritional Therapy and Metabolism, 28, (3), 101-109.
Calder, Philip C. (2010) Marine omega-3 fatty acids and inflammation. Journal of Lipid Nutrition, 19, (2), 233-244.
Madden, Jacqueline, Coward, Jenifer C., Shearman, Cliff P., Grimble, Robert F. and Calder, Philip C. (2010) Hsp70 expression in monocytes from patients with peripheral arterial disease and healthy controls: monocyte Hsp70 in PAD. Cell Biology and Toxicology, 26, (3), 215-223. (doi:10.1007/s10565-009-9134-x). (PMID:19672680).
Calder, Philip C. (2010) Editors' conflict of interest. British Journal Of Nutrition, 103, (1), 1-2. (doi:10.1017/S0007114509993412).
Calder, P.C. (2010) Lipid-laden dendritic cells fail to function. Cell Research, 20, 1089-1091. (doi:10.1038/cr.2010.124). (PMID:20805845).
Calder, P.C., Dangour, A.D., Diekman , C., Eilander, A., Koletzko, B., Meijer, G.W., Mozaffarian, D. and Niinikoski, H. (2010) Essential fats for future health. [in special issue: Proceedings of the 9th Unilever Nutrition Symposium, 26–27 May 2010] European Journal of Clinical Nutrition, 64, supplement 4, S1-S13. (d10.1038/ejcn.2010.242).
Childs, Caroline E., Romeu-Nadd, Meritxell , Burdge, Graham C. and Calder, Philip C. (2009) The polyunsaturated fatty acid composition of hepatic and plasma lipids differ by both sex and dietary fat intake in rats. Journal of Nutrition, 140, (2), 245-250. (doi:10.3945/jn.109.115691).
Calder, P.C. (2009) Editors' conflicts of interest. British Journal of Nutrition, 103, (1-2), 1-2. (doi:10.1017/S0007114509993412).
Calder, Philip C. (2009) Anti-inflammatory actions of marine-derived omega-3 fatty acids. Omega-3 Learning for Health & Medicine, (3)
Calder, Phillip C. (2009) Fatty acids and immune function: relevance to inflammatory bowel diseases. International Reviews of Immunology, 28, (6), 506-534. (doi:10.3109/08830180903197480).
Calder, Philip C. (2009) Editorial. BJN impact factor rises. British Journal of Nutrition, 102, 1243-1245. (doi:10.1017/S0007114509991619).
Galli, Claudio and Calder, Philip C. (2009) Effect of fat and fatty acid intake on inflammatory and immune responses: a critical review. Annals of Nutrition and Metabolism, 55, (1-3), 123-139. (doi:10.1159/000228999).
Calder, Philip C. (2009) Comment on "current choices in omega 3 supplementation". Nutrition Bulletin, 34, (3), 332-334. (doi:10.1111/j.1467-3010.2009.01774_1.x).
Tull, Samantha P., Yates, Clara M., Maskrey, Benjamin H., O'Donnell, Valerie B., Madden, Jackie, Grimble, Robert F., Calder, Philip C., Nash, Gerard B. and Rainger, G. Ed (2009) Omega-3 fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment. PLOS Biology, 7, (8), 1-11. (doi:10.1371/journal.pbio.1000177). (PMID:19707265).
Singer, Pierre, Berger, Mette M., Van den Berghe, Greet , Biolo, Gianni, Calder, P.C., Forbes, Alastair, Griffiths, Richard, Kreyman, Georg, Leverve, Xavier and Pichard, Claude (2009) ESPEN guidelines on parental nutrition: intensive care. Clinical Nutrition, 28, (4), 387-400. (doi:10.1016/j.clnu.2009.04.024).
Calder, Philip C. (2009) Participating in peer review is both a privilege and a professional duty. British Journal of Nutrition, 102, 1 -2. (doi:10.1017/S0007114509289070).
Damsgaard, C.T., Lauritzen, L., Calder, P.C., Kjaer, T.R. and Frokiaer, H. (2009) Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men. Journal of Nutrition, 139, 1410-1414. (doi:10.3945/jn.108.102269).
Burdge, Graham C., Powell, Jonathan, Dadd, Tony, Talbot, Duncan, Civil, Jacqueline and Calder, Philip C. (2009) Acute consumption of fish oil improves postprandial VLDL profiles in healthy men aged 50 to 65 years. British Journal of Nutrition, 102, (1), 160-165. (doi:10.1017/S0007114508143550). (PMID:19138437).
Calder, P.C., Albers, R., Antoine, J.M., Blum, S., Bourdet-Sicard, R., Ferns, G.A., Folkerts, G., Friedmann, P.S., Frost, G.S., Guarner, F., Løvik, M., Macfarlane, S., Meyer, P.D., M'Rabet, L., Serafini, M., van Eden, W., van Loo, J., Van Dias, W., Vidry, S., Winklhofer-Roob, B.M. and Zhao, J. (2009) Inflammatory disease processes and interactions with nutrition. British Journal of Nutrition, 101, (Supplement S1), S1-S45. (doi:10.1017/S0007114509377867).
Calder, P.C. and Yaqoob, P (2009) Omega-3 polyunsaturated fatty acids and human health outcomes. Biofactors, 35, (3), 266-272.
Calder, P.C. (2009) The use of n-3 polyunsaturated fatty acids as therapeutic agents for inflammatory diseases. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry, 9, (1), 45-54. (doi:10.2174/187152209788009788).
Thienprasert, Alice, Samuhaseneetoo, Suched, Popplestone, Kathryn, West, Annette L., Miles, Elizabeth A. and Calder, Philip C. (2009) Fish oil N-3 polyunsaturated fatty acids selectively affect plasma cytokines and decrease illness in Thai schoolchildren: a randomized, double-blind, placebo-controlled intervention trial. Journal of Pediatrics, 154, (3), 391-395. (doi:10.1016/j.jpeds.2008.09.014).
Calder, Philip C. (2009) Who should be an author? British Journal of Nutrition, 101, (6), 775-775. (doi:10.1017/S0007114509289082). (PMID:19278563).
Calder, Philip C., Damsgaard, Camilla T., Lauritzen, Lotte, Kjær, Tanja M.R. and Frøkiær, Hanne (2009) Whole-blood culture is a valid low-cost method to measure monocytic cytokines - a comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes. Journal of Immunological Methods, 340, 95 -101. (doi:10.1016/j.jim.2008.10.005 ).
Calder, Philip C. (2009) BJN to publish more issues and more papers in 2009. British Journal of Nutrition, 101, (1), 1-1. (doi:10.1017/S0007114508076228).
Calder, Phillip C. and Yaqoob, Parveen (2009) Understanding omega-3 polyunsaturated fatty acids. Postgraduate Medicine, 121, (6), 148-157. (doi:10.3810/pgm.2009.11.2083 ).
Calder, Phillip C. (2009) Polyunsaturated acids and inflammation: therapeutic potential in rheumatoid arthritis. Current Rheumatology Reviews, 5, (4), 214-225.
Calder, Philip C. (2009) Omega-3-Fettsäuren: entweder regelmässig fettreichen fisch essen oder fischölkapseln schlucken. Schweizer Zeitscrift für Ernährungsmedizin / Swiss Journal of Integrative Medicine, 5, 159-164.
Lomax, Amy R. and Calder, Philip C. (2009) Prebiotics, immune function, infection and inflammation; a review of the evidence. British Journal of Nutrition, 101, 633-658. (doi:10.1017/S0007114508055608). (Submitted).
Calder, P.C. (2008) Omega-3 fatty acids, atherosclerosis and CVD outcome. Journal of Clinical Lipidology, 2, (5), S38. (doi:10.1016/j.jacl.2008.08.084).
Calder, P.C. (2008) Record citations in 2007, but impact factor slips. British Journal of Nutrition, 100, (4), 687-689. (doi:10.1017/S0007114508066816).
Rerkasem, Kittipan, Gallagher, Patrick J., Grimble, Robert F., Calder, Philip C. and Shearman, Clifford P. (2008) Managing hypercholesterolemia and its correlation with carotid plaque morphology in patients undergoing carotid endarterectomy. Vascular Health and Risk Management, 4, (6), 1259-1264. (doi:10.2147/VHRM.S3729). (PMID:19337539).
Rerkasem , Kittipan, Gallagher, Patrick J., Grimble, Robert F., Calder, Philip C. and Shearman, Clifford P. (2008) Managing hypercholesterolemia and its correlation with carotid plaque morphology in patients undergoing crotid endarterectomy. Vascular Health and Risk Management, 4, (6), 1259-1264.
Caslake, Muriel J., Miles, Elizabeth A., Kofler, Bettina M., Lietz, Georg, Curtis, Peter, Armah, Christopher K., Kimber, Alan C., Grew, Jilly P., Farrell, Lesley, Stannard, Julie, Napper, Frances L., Sala-Vila, Aleix, West, Annette L., Mathers, John C., Packard, Christopher, Williams, Christine M., Calder, Philip C. and Minihane, Anne M. (2008) Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study. American Journal of Clinical Nutrition, 88, (3), 618-629. (PMID:18779276).
Madden, Jacqueline, Carrero, Juan J., Brunner, Andreas, Dastur, Neville, Shearman, Cliff P., Calder, Philip C. and Grimble, Robert F. (2008) Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men. Prostaglandins, Leukotrienes and Essential Fatty Acids, 78, (6), 327-335. (doi:10.1016/j.plefa.2008.04.003).
Yusof, H.M. and Calder, P.C. (2008) The effect of moderate dose of EPA+DHA on lipid profile and inflammatory markers in middle-aged men. Proceedings of the Nutrition Society, 67, (OCE1), E81. (doi:10.1017/S0029665108006903).
Calder, P.C., Albers, R., Antoine, J.-M., Blum, S., Bourdet-Sicard, R., Ferns, G.A., Folkerts, G., Friedman, P.S., Frost, G.S., Guarner, F., Lovik, M., Macfarlane, S., Meyer, P.D., M'Rabet, L., Serafini, M., van Eden, W., van Loo, J., vas Dias, W., Vidry, S., Winklhofer-Roob, B.M. and Zhao, J. (2008) Nutrition and inflammatory processes. [in special issue: OCE1 (1st International Immunonutrition Workshop, Valencia, 3–5 October 2007, Valencia, Spain)] Proceedings of the Nutrition Society, 67, (E9) (doi:10.1017/S0029665108006186).
Yates, Clara, Tull, Samantha, Madden, Jacki, Calder, Philip, Grimble, Robert, Nash, Gerard and Rainger, Ed (2008) The anti-inflammatory effects of the n-3PUFA, eicosapentaenoic acid, reveal a new and essential regulatory step in neutrophil migration across endothelial cells that requires prostaglandin-D2. FASEB Journal, 22
Yusof, Hayati M., Miles, Elizabeth A. and Calder, Philip (2008) Influence of very long-chain n-3 fatty acids on plasma markers of inflammation in middle-aged men. Prostaglandins, Leukotrienes and Essential Fatty Acids, 78, (3), 219-228. (doi:10.1016/j.plefa.2008.02.002). (PMID:18403189).
Childs, Caroline E., Romeu-Nadal, Meritxell, Burdge, Graham C. and Calder, Philip C. (2008) Gender differences in the n-3 fatty acid content of tissues. Proceedings of the Nutrition Society, 67, (1), 19-27. (doi:10.1017/S0029665108005983).
Burdge, G.C., Slater-Jefferies, J.L., Grant, R.A., Chung, W.S., West, A.L., Lillycrop, K.A., Hanson, M.A. and Calder, P.C. (2008) Sex, but not maternal protein or folic acid intake, determines the fatty acid composition of hepatic phospholipids, but not of triacylglycerol, in adult rats. Prostaglandins, Leukotrienes and Essential Fatty Acids, 78, (1), 73-79. (doi:10.1016/j.plefa.2007.10.028).
Calder, P.C. (2008) Controversies in clinical nutrition: omega-3 fatty acids in parenteral nutrition. Nutritional Therapy and Metabolism, 26, (1), 15-22.
Calder, P.C. and Deckelbaum, R.J. (2008) Omega-3 fatty acids: time to get the messages right! Current Opinion in Clinical Nutrition & Metabolic Care, 11, (2), 91-93.
Madden, J., Shearman, C.P., Dunn, R.L., Dastur, N.D., Tan, R.M., Nash, G.B., Rainger, G.E., Brunner, A., Calder, P.C. and Grimble, R.F. (2008) Altered monocyte CD44 expression in peripheral arterial disease is corrected by fish oil supplementation. Nutrition, Metabolism and Cardiovascular Diseases, 19, (4), 247-252. (doi:10.1016/j.numecd.2008.06.011).
Miles, Elizabeth A., Rees, D, Banerjee, T, Cazzola, R, Lewis, C , Wood, R , Oates, R, Tallant, A, Cestaro, B, Yaqoob, P, Wahle, KWJ and Calder, P.C. (2008) Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations. Atherosclerosis, 196, (1), 298-305. (doi:10.1016/j.atherosclerosis.2006.11.002). (PMID:17118371).
Calder, Philip C. (2008) Increasing transparency in the British Journal of Nutrition. British Journal of Nutrition, 99, 217-218. (doi:10.1017/S0007114507894451).
Calder, Philip C. (2008) Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases. Molecular Nutrition & Food Research, 52, (8), 885-897. (doi:10.1002/mnfr.200700289).
Calder, P.C. (2008) Editorial. Record citations in 2007, but impact factor slips. British Journal of Nutrition, 100, (4), 687-689. (doi:10.1017/S0007114508066816).
Calder, Philip C. (2008) The relationship between the fatty acid composition of immune cells and their function. Prostaglandins, Leukotrienes and Essential Fatty Acids, 79, (3-5), 101-108. (doi:10.1016/j.plefa.2008.09.016).
Sala-Vila, A., Miles, E. A. and Calder, P. C. (2008) Fatty acid composition abnormalities in atopic disease: evidence explored and role in the disease process examined. Clinical and Experimental Allergy, 38, (9), 1432-1450. (doi:10.1111/j.1365-2222.2008.03072.x).
Luu, Nguyet-Thin, Madden, Jackie, Calder, Philip C., Grimble, Robert F., Shearman, Cliff P., Chan, Tim, Dastur, Neville, Howell, William M., Rainger, G. Ed and Nash, Gerard B. (2007) Dietary supplementation with fish oil modifies the ability of human monocytes to induce an inflammatory response. Journal of Nutrition, 137, (12), 2769-2774.
Calder, P.C. (2007) Immunomodulation by omega-3 fatty acids. Prostaglandin Leucotrienes and Essential Fatty Acids, 77, (5-6), 327-335. (doi:10.1016/j.plefa.2007.10.015).
Yaqoob, Parveen and Calder, Philip C. (2007) Fatty acids and immune function: new insights into mechanisms. British Journal of Nutrition, 98, (Supplement S1), S41-S45. (doi:10.1017/S0007114507832995).
Marcos, Ascensión and Calder, Philip C. (2007) Introduction: first international immunonutrition workshop. British Journal of Nutrition, 98, supplement 1, S1-S2. (doi:10.1017/S0007114507833022).
Burdge, G.C., Sala-Vila, A., West, A.L., Robson, H.J.L., Le Fevre, L.W., Powell, J. and Calder, P.C. (2007) The effect of altering the 20:5n-3 and 22:6n-3 content of a meal on the postprandial incorporation of n-3 polyunsaturated fatty acids into plasma triacylglycerol and non-esterified fatty acids in humans. Prostaglandins, leukotrienes, and essential fatty acids, 77, (1), 59-65. (doi:10.1016/j.plefa.2007.06.003).
Luu, N.T., Madden, J., Calder, P.C., Grimble, R.F., Shearman, C.P., Chan, T., Tull, S.P., Dastur, N., Rainger, G.E. and Nash, G.B. (2007) Comparison of the pro-inflammatory potential of monocytes from healthy adults and those with peripheral arterial disease using an in vitro culture model. Atherosclerosis, 193, (2), 259-268. (doi:10.1016/j.atherosclerosis.2006.08.050).
Diakogiannaki, Eleftheria, Dhayal, Shalinee, Childs, Caroline E., Calder, Philip C., Welters, Hannah J. and Morgan, Noel G. (2007) Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells. Journal of Endocrinology, 194, (2), 283-291. (doi:10.1677/JOE-07-0082).
Cazzola, Roberta, Russo-Volpe, Samantha, Miles, Elizabeth A., Rees, Dinka, Banerjee, Tapati, Roynette, Catherine E., Wells, Solenne J., Goua, Marie, Wahle, Klaus W.J., Calder, Philip C., Cestaro, B and Benvenuto, Cestaro (2007) Age and dose dependent effects of an eicosapentaemoic acid-rich oil on cardiovascular risk factors in healthy male subjects. Atherosclerosis, 193, (1), 159-167. (doi:10.1016/j.atherosclerosis.2006.06.008).
Cazzola, Roberta, Russo-Volpe, Samantha, Miles, Elizabeth A., Rees, Dinka, Banerjee, Tapati, Roynette, Catherine E., Wells, Solenne J., Goua, Marie, Wahle, Klaus W.J., Calder, Philip C. and Cestaro, Benvenuto (2007) Age- and dose-dependent effects of an eicosapentaenoic acid-rich oil on cardiovascular risk factors in healthy male subjects. Atherosclerosis, 193, (1), 159-167. (doi:10.1016/j.atherosclerosis.2006.06.008).
Cawood, A.L., Ding, R., Napper, F.L., Young, R., Williams, J., Ward, M., Gudmundsen, O., Payne, S., Vic, H., Shearman, C.P., Ye, S., Gallagher, P.J., Grimble, R.F. and Calder, P.C. (2007) Long-chain n-3 fatty acids enter advanced atherosclerotic plaques and are associated with decreased inflammation and decreased inflammatory gene expression. Proceedings of the Nutrition Society, 66, 1A-13A. (doi:10.1017/S0029665107005733).
Fuhrmann, Herbert, Miles, Elizabeth A., West, Anette L. and Calder, Philip C. (2007) Membrane fatty acids, oxidative burst and phagocytosis after enrichment of P388D1 monocyte/macrophages with essential 18-carbon fatty acids. Annals of Nutrition & Metabolism, 51, (2), 155-162. (doi:10.1159/000103276).
Madden, Jacqueline, Brunner, Andreas, Dastur, Neville D., Tan, Rebecca M., Nash, Gerard B., Rainger, G. Ed, Shearman, Cliff P., Calder, Philip C. and Grimble, Robert F. (2007) Fish oil induced increase in walking distance, but not ankle brachial pressure index, in peripheral arterial disease is dependent on both body mass index and inflammatory genotype. Prostaglandins, Leukotrienes and Essential Fatty Acids, 76, (6), 331-340. (doi:10.1016/j.plefa.2007.04.003).
Sijben, John W.C. and Calder, Philip C. (2007) Differential immunomodulation with long-chain n-3 PUFA in health and chronic disease. Proceedings of the Nutrition Society, 66, (2), 237-259. (doi:10.1017/S0029665107005472).
Calder, Philip C. and Yaqoob, Parveen (2007) Lipid rafts: composition, characterization, and controversies. Journal of Nutrition, 137, (3), 545-547.
Sala-Vila, Aleix, Barbosa, Vera M. and Calder, Philip C. (2007) Olive oil in parenteral nutrition. Current Opinion in Clinical Nutrition and Metabolic Care, 10, (2), 165-174. (doi:10.1097/MCO.0b013e32802bf787).
Calder, Philip C. (2007) Immunological parameters: what do they mean? Journal of Nutrition, 137, (3, Supplement 2), 773S-780S.
Mund, Rogéria C., Pizato, Nathalia, Bonatto, Sandro, Nunes, Everson A., Vicenzi, Thiago, Tanhoffer, Ricardo, de Oliveira, Heloisa H.P., Curi, Rui, Calder, Philip C. and Fernandes, Luiz C. (2007) Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. Prostaglandins, Leukotrienes and Essential Fatty Acids, 76, (2), 113-120. (doi:10.1016/j.plefa.2006.11.008).
Calder, Philip C. (2007) Floruit floreat. British Journal of Nutrition, 97, (1), 1-3. (doi:10.1017/S0007114507250482).
Calder, P.C., Dimitriadis, G. and Newsholme, P. (2007) Glucose metabolism in lymphoid and inflammatory cells and tissues. Current Opinion in Clinical Nutrition and Metabolic Care, 10, (4), 531-540.
Luu, N.T., Madden, J., Calder, P.C., Grimble, R.F., Shearman, C.P., Chan, T., Tull, S.P., Dastur, N., Rainger, G.E. and Nash, G.B. (2007) Comparison of the pro-inflammatory potential of monocytes from healthy adults and those with peripheral arterial disease using an in vitro culture model. Atherosclerosis, 193, (2), 259-268. (doi:10.1016/j.atherosclerosis.2006.08.050).
Dastur, N., Madden, J., Shearman, C., Calder, P., Grimble, R., Nash, G. and Rainger, E. (2007) Omega 3 fish oil improves walking distance in patients with peripheral arterial disease (PAD). British Journal of Surgery, 94, (Supplement 1), 4-4. (doi:10.1002/bjs.5765).
Wanten, G.J. and Calder, P.C. (2007) Immune modulation by parenteral lipid emulsions. The American journal of clinical nutrition, 85, (5), 1171-1184.
Calder, Philip C. (2007) Dietary arachidonic acid: harmful, harmless or helpful? British Journal of Nutrition, 98, (3), 451-453. (doi:10.1017/S0007114507761779).
Calder, P.C. (2007) Polyunsaturated fatty acids and inflammation. Prostaglandins, Leukotrienes and Essential Fatty Acids, 75, (3), 197-202.
Stanley, J.C., Elsom, R.L., Calder, P.C., Griffin, B.A., Harris, W.S., Jebb, S.A., Lovegrove, J.A., Moore, C.S., Riemersma, R.A. and Sanders, T.A. (2007) UK Food Standards Agency Workshop Report: the effects of the dietary n-6:n-3 fatty acid ratio on cardiovascular health. British Journal of Nutrition, 98, (6), 1305-1310.
Calder, Philip C. (2007) Immunonutrition in surgical and critically ill patients. British Journal of Nutrition, 98, supplement 1, S133-S139. (doi:10.1017/S0007114507832909).
Calder, P.C. (2007) Efectos antiinflamatorios y de establizacion de la placa de atheroma de los acidos grasos amega-3. Medicina Clinica Monografias, 8, (3), 25-30.
Calder, Philip C. (2007) Happy birthday BJN! British Journal of Nutrition, 98, (3), 447-450. (doi:10.1017/S0007114507803990).
Calder, Philip C. (2007) Polyunsaturated fatty acids alter the rules of engagement. Future Lipidology, 2, (1), 27-30. (doi:10.2217/17460875.2.1.27).
Tricon, S., Willers, S., Smit, H.A., Burney, P.G., Devereux, G., Frew, A.J., Halken, S., Høst, A., Nelson, M., Shaheen, S., Warner, J.O. and Calder, P.C. (2006) Nutrition and allergic disease. Clinical and Experimental Allergy Reviews, 6, (5), 117-188. (doi:10.1111/j.1365-2222.2006.00114.x).
Miles, Elizabeth A., Banerjee, Tapati and Calder, Philip C. (2006) Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. Prostaglandins, Leukotrienes and Essential Fatty Acids, 75, (1), 57-60. (doi:10.1016/j.plefa.2006.04.005).
Burdge, Graham C. and Calder, Philip C. (2006) Dietary α-linolenic acid and health-related outcomes: a metabolic perspective. Nutrition Research Reviews, 19, (1), 26-52. (doi:10.1079/NRR2005113).
Calder, Philip C. (2006) N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Americ Journal of Clinical Nutrition, 83, (6), 1505S-1519S.
Calder, Philip C. (2006) n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. American Journal of Clinical Nutrition, 83, (6, Supplement 1), S1505-S1519.
Miles, Elizabeth A., Banerjee, Tapati, Wells, Solenne J. and Calder, Philip C. (2006) Limited effect of eicosapentaenoic acid on T-lymphocyte and natural killer cell numbers and functions in healthy young males. Nutrition, 22, (5), 512-519. (doi:10.1016/j.nut.2005.11.011).
England, A., Slater-Jefferies, J., Miles, E.A., Browning, L., Grimaldi, K., Gill-Garrison, R., Calder, P.C., Howell, W.M. and Grimble, R.F. (2006) RRR-alpha-tocopherol supplementation has pro- and anti-inflammatory and pro- and antioxidant effects in peripheral blood mononuclear cells in healthy middle-aged men depending upon dosage and genotype for xenobiotic metabolising enzymes. Proceedings of the Nutrition Society, 65, (OCA-B), p.69A. (doi:10.1017/S002966510600526X).
Madden, J., Brunner, A., Carrero, J.J., Hadley, J., Tan, B., Shearman, C.P., Calder, P.C., Rainger, E., Nash, G., Luu, T. and Grimble, R.F. (2006) Influence of CD36 gene polymorphisms on the response of cardiovascular risk factors to fish oil supplementation in middle aged men. Proceedings of the Nutrition Society, 65, (OCA-B), p.88A. (doi:10.1017/S002966510600526X).
Madden, J., Brunner, A., Carrero, J.J., Hadley, J., Tan, B., Dastur, N., Shearman, C.P., Calder, P.C., Rainger, E., Nash, G., Luu, T. and Grimble, R.F. (2006) Polymorphisms at IL-6-174 and TNF-a-308 and body mass index modulate the effects of fish oil supplementation on cytokine production by monocytes from healthy middle aged men. Proceedings of the Nutrition Society, 65, (OCA-B), p.71A. (doi:10.1017/S002966510600526X).
Slater-Jefferies, J., England, A., Cichon, B., Grimaldi, K., Gill-Garrison, R., Calder, P.C., Howell, W.M., Armstrong, R. and Grimble, R.F. (2006) Influence of superoxide dismutase polymorphism and overweight status on clinical outcome and oxidant production and stress in healthy middle-aged men and rheumatoid patients receiving high-dose RRR-alpha-tocopherol supplementation. Proceedings of the Nutrition Society, 65, (OCA-B), p.72A. (doi:10.1017/S002966510600526X).
Rees, Dinka, Miles, Elizabeth A., Banerjee, Tapati, Wells, Solenne J., Roynette, Catherine E., Wahle, Klaus W.J. and Calder, Philip C. (2006) Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men. American Journal of Clinical Nutrition, 83, (2), 331-342.
Calder, P.C. (2006) Abnormal fatty acid profiles occur in atopic dermatitis but what do they mean? Clinical and Experimental Allergy, 36, (2), 138-141. (doi:10.1111/j.1365-2222.2006.02433.x).
Calder, Philip C. (2006) The British Journal of Nutrition, an international journal that continues to develop. British Journal of Nutrition, 96, (1), 1-3. (doi:10.1079/BJN20061881).
Calder, Philip C. (2006) Carpe diem. Journal of Nutrition, 95, (1), 1-4. (doi:10.1079/BJN20051654).
Calder, Phillip C. (2006) Branched-chain amino acids and immunity. Journal of Nutrition, 136, (1), 288S-293S.
Calder, Philip C. (2006) Use of fish oil in parenteral nutrition: rationale and reality. Proceedings of the Nutrition Society, 65, (3), 264-277. (doi:10.1079/PNS2006500).
Calder, Philip C. (2006) Branched-chain amino acids and immunity. Journal of Nutrition, 136, (1), 288S-293S.
Burdge, Graham C. and Calder, Philip C. (2006) Dietary alpha-linolenic acid and health-related outcomes: a metabolic perspective. Nutrition Research Reviews, 19, (1), 26-52. (doi:10.1079/NRR2005113).
Calder, P.C., Krauss-Etschmann, S., De Jong, E.C., Dupont, C., Frick, J.S., Frokiaer, H., Heinrich, J., Garn, H., Koletzko, S., Lack, G., Mattelio, G., Renz, H., Sangild, P.T., Schrezenmeir, J., Stulnig, T.M., Thymann, T., Wold, A.E. and Koletzko, B. (2006) Early nutrition and immunity - progress and perspectives. British Journal Of Nutrition, 96, (4), 774-790. (doi:10.1079/BJN20061917). (PMID:17010239).
Pizato, N., Bonatto, S., Piconcelli, M., De Souza, L.M., Sassaki, G.L., Naliwaiko, K., Nunes, E.A., Curi, R., Calder, P.C. and Fernandes, L.C. (2006) Fish oil alters T-lymphocyte proliferation and macrophage responses in Walker 256 tumor-bearing rats. Nutrition, 22, (4), 425-432.
Calder, Philip C. (2006) Long-chain polyunsaturated fatty acids and inflammation. Scandinavian Journal of Food & Nutrition, 50, (Supplement 2), 54-61. (doi:10.1080/17482970601066389).
Tricon, S., Burdge, G.C., Jones, E.L., Russell, J.J., El-Khazen, S., Moretti, E., Hall, W.L., Gerry, A.B., Leake, D.S., Grimble, R.F., Williams, C.M., Calder, P.C. and Yaqoob, P. (2006) Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men. The American journal of clinical nutrition, 83, (4), 744-753.
Calder, P.C. and Deckelbaum, R.J. (2006) CD36: taste the difference? Current Opinion in Clinical Nutrition and Metabolic Care - home, 9, (2), 77-78.
Bakewell, L., Burdge, G.C. and Calder, P.C. (2006) Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets. British Journal of Nutrition, 96, (1), 93-99. (doi:10.1079/BJN20061801).
Yaqoob, P., Tricon, S., Williams, C.M., Grimble, R.F., Burdge, G.C. and Calder, P.C. (2006) Conjugated linoleic acid and human health-related outcomes. Nutrition Bulletin, 31, (2), 93-99. (doi:10.1111/j.1467-3010.2006.00560.x).
Trebble, Timothy M., Stroud, Mike A., Wootton, Stephen A., Calder, Philip C., Fine, David R., Mullee, Mark A., Moniz, Caje and Arden, Nigel K. (2005) High-dose fish oil and antioxidants in Crohn's disease and the response of bone turnover: a randomised controlled trial. British Journal of Nutrition, 94, (2), 253-261. (doi:10.1079/BJN20051466).
Tricon, S., Burdge, G.C., Williams, C.M., Calder, P.C. and Yaqoob, P. (2005) The effects of conjugated linoleic acid on human health-related outcomes. Proceedings of the Nutrition Society, 64, (2), 171-182. (doi:10.1079/PNS2005418).
Calder, P.C. (2005) Polyunsaturated fatty acids and inflammation. Biochemical Society Transactions, 33, (2), 423-427.
Pizato, Nathalia, Bonatto, Sandro, Yamazaki , Ricardo K., Aikawa, Julia, Nogata, Claudia, Mund, Rogeria C., Nunes, Everson A., Piconcelli, Maressa, Naliwaiko, Katya, Curi, Rui, Calder, Philip C. and Fernandes, Luiz Claudio (2005) Ratio of n-6 to n-3 fatty acids in the diet arrects tumor growth and cachexia in Walker 256 tumor-bearing rats. Nutrition and Cancer, 53, (2), 194-201. (doi:10.1207/s15327914nc5302_8 ).
Albers, R., Antoine, J.M., Bourdet-Sicard, R., Calder, P.C., Gleeson, M., Lesourd, B., Samartin, S.I.R., Van Loo, J., Vas Dias, F. W. and Watzl, B. (2005) Markers to measure immunomodulation in human nutrition intervention studies. British Journal of Nutrition, 94, (3), 452-481. (doi:10.1079/BJN20051469).
Cawood, A. L., Carroll, M. P., Wootton, S. A. and Calder, P. C. (2005) Is there a case for n-3 fatty acid supplementation in cystic fibrosis? Current Opinion in Clinical Nutrition & Metabolic Care, 8, (2), 153-159.
Deckelbaum, R. J. and Calder, P. C. (2005) Lipids: how do we convert experimental data to policy? Current Opinion in Clinical Nutrition and Metabolic Care, 8, (2), 113-114.
Burdge, Graham C. and Calder, Philip C. (2005) a-linolenic acid metabolism in adult humans: the effects of gender and age on conversation to longer chain polyunsaturated fatty acids. European Journal of Lipid Science and Technology, 107, (6), 426-439. (doi:10.1002/ejlt.200501145 ).
Miles, E.A., Zoubouli, P. and Calder, P.C. (2005) Effects of polyphenols on human Th1 and Th2 cytokine production. Clinical Nutrition, 24, (5), 780-784. (doi:10.1016/j.clnu.2005.04.001).
Bouriche, H., Miles, E.A., Selloum, L. and Calder, P.C. (2005) Effect of Cleome arabica leaf extract, rutin and quercetin on soybean lipoxygenase activity and on generation of inflammatory eicosanoids by human neutrophils. Prostaglandins, Leukotrienes and Essential Fatty Acids, 72, (3), 195-201. (doi:10.1016/j.plefa.2004.10.018).
Burdge, Graham C. and Calder, Philip C. (2005) Plasma cytokine response during the postprandial period: a potential causal process in vascular disease? British Journal of Nutrition, 93, (1), 3-9. (doi:10.1079/BJN20041282).
Burdge, Graham C. and Calder, Philip C. (2005) α-Linolenic acid metabolism in adult humans: the effects of gender and age on conversion to longer-chain polyunsaturated fatty acids. European Journal of Lipid Science and Technology, 107, (6), 426-439. (doi:10.1002/ejlt.200501145).
Burdge, Graham C., Tricon, Sabine, Morgan, Rebecca, Kliem, Kirsty E., Childs, Caroline, Jones, Emma, Russell, Jennifer J., Grimble, Robert F., Williams, Christine M., Yaqoob, Parveen and Calder, Philip C. (2005) Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18 : 1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids. British Journal of Nutrition, 94, (2), 237-243. (doi:10.1079/BJN20051506).
Jones, E.L., Shingfield, K.J., Kohen, C., Jones, A.K., Lupoli, B., Grandison, A.S., Beever, D.E., Williams, C.M., Calder, P.C. and Yaqoob, P. (2005) Chemical, physical, and sensory properties of dairy products enriched with conjugated linoleic acid. Journal of Dairy Science, 88, (8), 2923-2937.
Burdge, Graham C., Derrick, Peter R., Russell, Jennifer J., Tricon, Sabine, Kew, Samantha, Banerjee, Tapati, Grimble, Robert F., Williams, Christine M., Yaqoob, Parveen and Calder, Philip C. (2005) Incorporation of cis-9, trans-11 or trans-10, cis-12 conjugated linoleic acid into human erythrocytes in vivo. Nutrition Research, 25, (1), 13-19. (doi:10.1016/j.nutres.2004.08.002).
Ruxton, C.H.S., Calder, P.C., Reed, S.C. and Simpson, M.J.A. (2005) The impact of long-chain n-3 polyunsaturated fatty acids on human health. Nutrition Research Reviews, 18, (1), 113-129. (doi:10.1079/NRR200497).
Burdge, Graham C. and Calder, Philip C. (2005) Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reproduction, Nutrition, Development, 45, (5), 581-597. (doi:10.1051/rnd:2005047).
Tricon, S., Burdge, G.C., Kew, S., Banerjee, T., Russell, J.J., Grimble, R.F., Williams, C.M., Calder, P.C. and Yaqoob, P. (2004) Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on immune cell function in healthy humans. American Journal of Clinical Nutrition, 80, (6), 1626-1633.
Calder, Philip C. (2004) ISSFAL 2004. Lipids, 39, 1043.
Trebble, Timothy M., Arden, Nigel K., Wootton, Stephen A., Calder, Philip C., Mullee, Mark A., Fine, David R. and Stroud, Mike A. (2004) Fish oil and antioxidants alter the composition and function of circulating mononuclear cells in Crohn disease. American Journal of Clinical Nutrition, 80, (5), 1137-1144.
Trebble, Timothy M., Arden, Nigel K., Wootton, Stephen A., Calder, Philip C., Mullee, Mark A., Fine, David R. and Stroud, Mike A. (2004) Fish oil and antioxidants alter the composition and function of circulating mononuclear cells in Crohn disease. American Journal of Clinical Nutrition, 80, (5), 1137-1144.
Tricon, S., Burdge, G.C., Kew, S., Banerjee, T., Russell, J.J., Jones, E.L., Grimble, R.F., Williams, C.M., Yaqoob, P. and Calder, P.C. (2004) Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. American Journal of Clinical Nutrition, 80, (3), 614-620.
Trebble, Timothy M., Arden, Nigel K., Wootton, Stephen A., Mullee, Mark A., Calder, Philip C., Burdge, Graham C., Fine, David R. and Stroud, Mike A. (2004) Peripheral blood mononuclear cell fatty acid composition and inflammatory mediator production in adult Crohn's disease. Clinical Nutrition, 23, (4), 647-655. (doi:10.1016/j.clnu.2003.10.017).
Miles, Elizabeth A., Banerjee, Tapati, Dooper, Maaike M. B. W., M'Rabet, Laura, Graus, Yvo M. F. and Calder, Philip C. (2004) The influence of different combinations of y-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects. British Journal of Nutrition, 91, (6), 893-903. (doi:10.1079/BJN20041131 ). (PMID:15182393).
Morgan, Angharad R., Rerkasem, Kittipan, Gallagher, Patrick J., Zhang, Baiping, Morris, Gareth E., Calder, Philip C., Grimble, Robert F., Eriksson, Per, McPheat, William L., Shearman, Clifford P. and Ye, Shu (2004) Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics. Stroke, 35, (6), 1310-1315. (doi:10.1161/01.STR.0000126822.01756.99).
Burdge, Graham C., Lupoli, Berit, Russell, Jennifer J., Tricon, Sabine, Kew, Samantha, Banerjee, Tapati, Shingfield, Kevin J., Beever, David E., Grimble, Robert F., Williams, Christine M., Yaqoob, Parveen and Calder, Philip C. (2004) Incorporation of cis-9, trans-11 or trans-10, cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. The Journal of Lipid Research, 45, (4), 736-741. (doi:10.1194/jlr.M300447-JLR200).
Sanderson, Peter, Olthof , Margreet, Grimble, Robert F., Calder, Philip C., Griffin, Bruce A., de Roos, Nicole M., Belch, Jill J.F., Muller, David P.R. and Vita, Joseph A. (2004) Dietary lipids and vascular function: UK Foods Standards Agency Workshop report. British Journal of Nutrition, 91, (3), 491-500. (doi:10.1079/BJN20031034).
Dunstan, J.A., Mori, T.A., Barden, A., Beilin, L.J., Holt, P.G., Calder, P.C., Taylor, A.L. and Prescott, S.L. (2004) The effects of n-3 polyunsaturated fatty acid supplementation in pregnancy on maternal and fetal erythrocyte fatty acid composition. European Journal of Clinical Nutrition, 58, (3), 429-437. (doi:10.1038/sj.ejcn.1601825).
Newson, R.B., Shaheen, S.O., Henderson, A.J., Emmett, P.M., Sherriff, A. and Calder, P.C. (2004) Umbilical cord and maternal blood red cell fatty acids and early childhood wheezing and eczema. Journal of Allergy and Clinical Immunology, 114, (3), 531-537. (doi:10.1016/j.jaci.2004.05.010).
Prescott, S. L. and Calder, P. C. (2004) N-3 polyunsaturated fatty acids and allergic disease. Current Opinion in Clinical Nutrition & Metabolic Care, 7, (2), 123-129.
Deckelbaum, Richard J., Calder, Phillip C. and Carpentier, Yvon A. (2004) Using different intravenous lipids: underutilized therapeutic approaches? Current Opinion in Clinical Nutrition & Metabolic Care, 7, (2), 113-115.
Rerkaem, K., Shearman , C., Garry, J., Yaqoob, P., Grimble, R . and Calder, P.C. (2004) Effect of type of anaesthesis during carotid endarterectomy on plasma levels of interleukin-6 and interleukin-10. Journal of the Thai Vascular Society, 1, 22-25.
Burdge, Graham C., Lupoli, Berit, Russell, Jennifer J., Tricon, Sabine, Kew, Samantha, Banerjee, Tapati, Shingfield, Kevin J., Beever, David E., Grimble, Robert F., Williams, Christine M., Yaqoob, Parveen and Calder, Philip C. (2004) Incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. Journal of Lipid Research, 45, (4), 736-741. (doi:10.1194/jlr.M300447-JLR200).
Markovic, Olivera, O'Reilly, Gillian, Fussell, Helen M., Turner, Stephen J., Calder, Philip C., Howell, William M. and Grimble, Robert F. (2004) Role of single nucleotide polymorphisms of pro-inflammatory cytokine genes in the relationship between serum lipids and inflammatory parameters, and the lipid-lowering effect of fish oil in healthy males. Clinical Nutrition, 23, (5), 1084-1095. (doi:10.1016/j.clnu.2004.02.002).
Trebble, T.M., Wootton, S.A., Stroud, M.A., Mullee, M.A., Calder, P.C., Fine, D.R., Moniz, C. and Arden, N.K. (2004) Laboratory markers predict bone loss in Crohn's disease: relationship to blood mononuclear cell function and nutritional status. Alimentary Pharmacology & Therapeutics, 19, (10), 1063-1071. (doi:10.1111/j.1365-2036.2004.01943.x).
Calder, P.C. (2004) Polyunsaturated fatty acids and inflammation. Oleagineux Corps gras Lipides, 11, (1), 38-45.
Sanderson, P., Olthof, M., Grimble, R.F., Calder, P.C., Griffin, B.A., De Roos, N.M., Belch, J.J.F., Muller, D.P.R. and Vita, J.A. (2004) Dietary lipids and vascular function: UK Food Standards Agency workshop report. British Journal of Nutrition, 91, (3), 491-500. (doi:10.1079/BJN20031034).
Elmes, M., Tew, P., Cheng, Z., Kirkup, S.E., Abayasekara, D.R., Calder, P.C., Hanson, M.A., Wathes, D.C. and Burdge, G.C. (2004) The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1686, (1-2), 139-147. (doi:10.1016/j.bbalip.2004.09.004).
Bonatto, Sandro J.R., Folador, Alessandra, Aikawa, Júlia, Yamazaki, Ricardo K., Pizatto, Nathalia, Oliveira, Heloisa H.P., Vecchi, Rodrigo, Curi, Rui, Calder, Phillip and Fernandes, Luiz C. (2004) Lifelong exposure to dietary fish oil alters macrophage responses in Walker 256 tumor-bearing rats. Cellular Immunology, 231, (1-2), 56-62. (doi:10.1016/j.cellimm.2004.12.001).
Cummings, John H., Antoine, Jean-Michel, Azpiroz, Fernando, Bourdet-Sicard, Raphaelle, Brandtzaeg, Per, Calder, Phillip C., Gibson, Glenn R., Guarner, Francisco, Isolauri, Erika, Pannemans, Daphne, Shortt, Colette, Tuijtelaars, Sandra and Watzl, Bernard (2004) PASSCLAIM - gut health and immunity. European Journal of Nutrition, 43, (2), ii118-ii173. (doi:10.1007/s00394-004-1205-4).
Miles, E.A., Banerjee, T., Dooper, M.M.B.W., M'Rabet, L., Graus, Y.M.F. and Calder, P.C. (2004) The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects. British Journal of Nutrition, 91, (6), 893-903. (doi:10.1079/BJN20041131).
Roynette, Catherine E., Calder, Philip C., Dupertuis, Yves M. and Pichard, Claude (2004) n-3 polyunsaturated fatty acids and colon cancer prevention. Clinical Nutrition, 23, (2), 139-151. (doi:10.1016/j.clnu.2003.07.005).
Calder, P.C. (2004) Omega-3 fatty acids: a matter of the heart. Nutrition- Primary Care Review, 3, 21.
Miles, Elizabeth A., Banerjee, Tapati and Calder, Philip C. (2004) The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. Prostaglandins Leukotrienes and Essential Fatty Acids, 70, (6), 529-538. (doi:10.1016/j.plefa.2003.11.008).
Trebble, T.M., Wootton, S.A., Stroud, M.A., Mullee, M.A., Calder, P.C., Fine, D.R., Moniz, C. and Arden, N.K. (2004) Laboratory markers predict bone loss in Crohn's disease: relationship to blood mononuclear cell function and nutritional status. Alimentary Pharmacology & Therapeutics, 19, (10), 1063-1071. (doi:10.1111/j.1365-2036.2004.01943.x).
Dunstan, J.A., Mori, T.A., Barden, A., Beilin, L.J., Holt, P.G., Calder, P.C., Taylor, A.L. and Prescott, S.L. (2004) Effects of n-3 polyunsaturated fatty acid supplementation in pregnancy on maternal and fetal erythrocyte fatty acid composition. European Journal of Clinical Nutrition, 58, (3), 429-437. (doi:10.1038/sj.ejcn.1601825).
Calder, P.C. (2003) Immunonutrition. Author's reply. British Medical Journal, 327, 683. (doi:10.1136/bmj.327.7416.683 ).
Trebble, Timothy M., Wootton, Stephen A., Miles, Elizabeth A., Mullee, Mark, Arden, Nigel K., Ballinger, Anne B., Stroud, Mike A., Burdge, Graham C. and Calder, Phillip C. (2003) Prostaglandin E2 production and T cell function after fish-oil supplementation: response to antioxidant cosupplementation. American Journal of Clinical Nutrition, 78, (3), 376-382.
Calder, Philip C. (2003) Immunonutrition. British Medical Journal, 327, (7407), 117-118. (doi:10.1136/bmj.327.7407.117).
Kew, Samantha, Banerjee, Tapati, Minihane, Anne M., Finnegan, Yvonne E., Muggli, Reto, Albers, Ruud, Williams, Christine M. and Calder, Philip C. (2003) Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function. American Journal of Clinical Nutrition, 77, (5), 1287-1295.
Trebble, T., Arden, N.K., Stroud, M.A., Wootton, S.A., Burdge, G.C., Miles, E.A., Ballinger, A.B., Thompson, R.L. and Calder, P.C. (2003) Inhibition of tumour necrosis factor-α and interleukin 6 production by mononuclear cells following dietary fish-oil supplementation in healthy men and response to antioxidant co-supplementation. British Journal of Nutrition, 90, (2), 405-412. (doi:10.1079/BJN2003892).
Togni, Valeria, Ota, Claudia, Folador, Alessandra, Junior, O. Tchaikovski, Aikawa, Julia, Yamazaki, Ricardo K., Freitas, Fabio A., Longo, Rita, Martins, Edgair F., Calder, Philip C., Curi, Rui and Fernandes, Luiz C. (2003) Cancer cachexia and tumor growth reduction in Walker 256 tumor-bearing rats supplemented with n-3 polyunsaturated fatty acids for one generation. Nutrition and Cancer, 46, (1), 52-58. (doi:10.1207/S15327914NC4601_07).
Calder, P.C. (2003) New evidence in support of the cardiovascular benefit of long-chain n-3 fatty acids. Italian Heart Journal, 4, (7), 427-429.
Burdge, G.C., Delange, E., Dubois, L., Dunn, R.L., Hanson, M.A., Jackson, A.A. and Calder, P.C. (2003) Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. British Journal of Nutrition, 90, (2), 345-352. (doi:10.1079/BJN2003909).
Thies, Frank, Garry, Jennifer M.C., Yaqoob, Parveen, Rerkasem, Kittipan, Williams, Jennifer, Shearman, Cliff P., Gallagher, Patrick J., Calder, Philip C. and Grimble, Robert F. (2003) Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial. Lancet, 361, (9356), 477-485. (doi:10.1016/S0140-6736(03)12468-3).
Kew, S., Wells, S., Thies, F., McNeill, G.P., Quinlan, P.T., Clark, G.T., Dombrowsky, H., Postle, A.D. and Calder, P.C. (2003) The effect of eicosapentaenoic acid on rat lymphocyte proliferation depends upon its position in dietary triacylglycerols. Journal of Nutrition. The American Society for Nutritional Sciences, 133, (12), 4230-4238.
Finnegan, Yvonne E., Minihane, Anne M., Leigh-Firbank, Elizabeth C., Kew, Samantha, Meijer, Gert W., Muggli, Reto, Calder, Philip C. and Williams, Christine M. (2003) Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. American Journal of Clinical Nutrition, 77, (4), 783-795.
Calder, P.C. (2003) Long-chain n-3 fatty acids and inflammation: potential application in surgical and trauma patients. Brazilian Journal of Medical and Biological Research, 36, (4), 433-446. (doi:10.1590/S0100-879X2003000400004).
Calder, P. C. and Deckelbaum, R. J. (2003) Fat as a physiological regulator: the news gets better. Current Opinion in Clinical Nutrition & Metabolic Care, 6, (2), 127-131.
Wallace, F.A., Miles, E.A. and Calder, P.C. (2003) Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects. British Journal of Nutrition, 89, (5), 679-689. (doi:10.1079/BJN1079/2002821).
Kew, S., Gibbons, E. S., Thies, F., McNeill, G. P., Quinlan, P. T. and Calder, P. C. (2003) The effect of feeding structured triacylglycerols enriched in eicosapentaenoic or docosahexaenoic acids on murine splenocyte fatty acid composition and leucocyte phagocytosis. British Journal of Nutrition, 90, (6), 1071-1080. (doi:10.1079/BJN2003996).
Finnegan, Yvonne E., Howarth, David, Minihane, Anne M., Kew, Samantha, Miller, George J., Calder, Philip C. and Williams, Christine M. (2003) Plant and marine derived (n-3) polyunsaturated fatty acids do not affect blood coagulation and fibrinolytic factors in moderately hyperlipidemic humans. Journal of Nutrition, 133, (7), 2210-2213.
Cavaglieri, Claudia R., Nishiyama, Anita, Fernandes, Luis Claudio, Curi, Rui, Miles, Elizabeth A. and Calder, Philip C. (2003) Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes. Life Sciences, 73, (13), 1683-1690. (doi:10.1016/S0024-3205(03)00490-9).
Calder, P.C. (2003) Immunonutrition. May have beneficial effects in surgical patients. British Medical Journal, 327, 117-118. (doi:10.1136/bmj.327.7407.117).
Calder, Philip C. and Yaqoob, Parveen (2003) Cardiovascular benefit of long chain n-3 fatty acids - The evidence gets stronger. Current Topics in Nutraceutical Research, 1, (2), 105-112.
Calder, P.C. (2003) Lipids and the critically ill patient. Nutrition and Critical Care, 8, 75-91.
Kew, Samantha, Banerjee, Tapati, Minihane, Anne M., Finnegan, Yvonne E., Williams, Christine M. and Calder, Philip C. (2003) Relation between the fatty acid composition of peripheral blood mononuclear cells and measures of immune cell function in healthy, free-living subjects aged 25-72 y1-3. American Journal of Clinical Nutrition, 77, (5), 1278-1286.
Yaqoob, P. and Calder, P.C. (2003) N-3 polyunsaturated fatty acids and inflammation in the arterial wall. European Journal of Medical Research, 8, (8), 337-354.
Calder, P.C. and Kew, S. (2002) The immune system: a target for functional foods? British Journal of Nutrition, 88, (Suppl. 2), S165-S177. (doi:10.1079/BJN2002682).
Grimble, Robert.F., Howell, W.Martin, Reilly, Gillian, Turner, Stephen.J., Markovic, Olivera, Hirrell, Sharon, East, J.Malcolm. and Calder, Philip.C. (2002) The ability of fish oil to suppress tumor necrosis factor alpha production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that influence tumor necrosis factor alpha production. American Journal of Clinical Nutrition, 76, (2), 454-459.
Grimble, Robert F., Howell, W. Martin, O’Reilly, Gillian, Turner, Stephen J., Markovic, Olivera, Hirrell, Sharon, East, J. Malcolm and Calder, Philip C. (2002) The ability of fish oil to suppress tumor necrosis factor alpha production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that influence tumor necrosis factor α production. American Journal of Clinical Nutrition, 76, (2), 454-459.
Grimm, H. and Calder, P.C. (2002) Immunonutrition. British Journal of Nutrition, 87, (Supplement s1), 1-1. (doi:10.1079/BJN2001450).
Calder, P.C., Yaqoob, P., Thies, F., Wallace, F.A. and Miles, E.A. (2002) Fatty acids and lymphocyte functions. British Journal of Nutrition, 87, (1), 31-48. (doi:10.1079/BJN2001455).
Calder, P.C. (2002) Dietary modification of inflammation with lipids. Proceedings of the Nutrition Society, 61, (3), 345-358.
Calder, P.C. and Grimble, R.F. (2002) Polyunsaturated fatty acids, inflammation and immunity. European Journal of Clinical Nutrition, 56, (3), S14-S19. (doi:10.1038/sj.ejcn.1601478).
Sanderson, P., Finnegan, Y.E., Williams, C.M., Calder, P.C., Burdge, G.C., Wootton, S.A., Griffin, B.A., Joe Millward, D., Pegge, N.C. and Bemelmans, W.J. (2002) UK Food Standards Agency α-linolenic acid workshop report. British Journal of Nutrition, 88, (5), 573-579. (doi:10.1079/BJN2002691).
Calder, P.C. (2002) Fatty acids and gene expression related to inflammation. Inflammation in Health Disease. Clinical Nutrition: Early Intervention. Nestle Nutrition Workshop Series. Clinical & Performance programme, 7, 19-40. (doi:10.1159/000067510).
Calder, P. C., Grimble, R. F. and Howell, W. M. (2002) Gene polymorphisms, inflammatory diseases and cancer. Proceedings of the Nutrition Society, 61, (4), 447-456. (doi:10.1079/PNS2002186).
Rerkasem, K., Shearman, C.P., Williams, J A., Morris, G.E., Phillips, M.J., Calder, P.C. and Grimble, R.F. (2002) C-reactive protein is elevated in symptomatic compared with asymptomatic patients with carotid artery disease. European Journal of Vascular and Endovascular Surgery, 23, (6), 505-509. (doi:10.1053/ejvs.2002.1632).
Calder, P. C. (2002) Conjugated linoleic acid in humans--reasons to be cheerful? Current Opinion in Clinical Nutrition & Metabolic Care, 5, (2), 123-126.
Calder, P. C. (2001) Fatty acid metabolism and eicosanoid synthesis. Clinical Nutrition, 20, (Suppl 4), 1-5.
Calder, Philip C. and Deckelbaum, Richard J. (2001) Fats in the new millennium: more complexity but a better understanding? Current Opinion in Clinical Nutrition & Metabolic Care, 4, (2), 89-91. (PMID:11224650).
Thies, Frank, Nebe-von-Caron, Gerhard, Powell, Jonathan R., Yaqoob, Parveen, Newsholme, Eric A. and Calder, Philip C. (2001) Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. American Journal of Clinical Nutrition, 73, (3), 539-548.
Calder, P. C. and Zurier, R. B. (2001) Polyunsaturated fatty acids and rheumatoid arthritis. Current Opinion in Clinical Nutrition & Metabolic Care, 4, (2), 115-121.
Thies, F., Miles, E.A., Nebe-von-Caron, G., Powell, J.R., Hurst, T.L., Newsholme, E.A. and Calder, P.C. (2001) Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. Lipids, 36, (11), 1183-1193.
Calder, Philip C. (2001) Polyunsaturated fatty acids, inflammation, and immunity. Lipids, 36, (9), 1007-1024. (L8650).
Miles, Elizabeth A., Thies, Frank, Wallace, Fiona A., Powell, Jonathan R., Hurst, Tina L., Newsholme, Eric A. and Calder, Philip C. (2001) Influence of age and dietary fish oil on plasma soluble adhesion molecule concentrations. Clinical Science (London), 100, (1), 91-100.
Miles, E.A., Wallace, F.A. and Calder, P.C. (2001) An olive oil-rich diet reduces scavenger receptor mRNA in murine macrophages. British Journal of Nutrition, 85, (2), 185-191. (doi:10.1079/BJN2000244).
Calder, P.C. (2001) Omega 3 polyunsaturated fatty acids, inflammation and immunity. World Review of Nutrition and Dietetics, 88, 109-116. (doi:10.1159/000059774).
Calder, P. C. (2001) Nutrition et fonction immunitaire (Nutrition and immune function). La Revue Francaise d'Endocrinologie Clinique, Nutrition, et Metabolisme, 15, (4), 286-297.
Wallace, Fiona A., Miles, Elizabeth A., Evans, Carl, Stock, Theresa E., Yaqoob, Parveen and Calder, Philip C. (2001) Dietary fatty acids influence the production of Th1- but not Th2-type cytokines. Journal of Leukocyte Biology, 69, (3), 449-457.
Calder, Philip C. (2001) The ratio of n-6 to n-3 fatty acids in the diet: impact on T lymphocyte function. European Journal of Lipid Science and Technology, 103, (6), 390-398. (doi:10.1002/1438-9312(200106)103:6<390::AID-EJLT390>3.0.CO;2-3).
Calder, Philip C. (2001) More good news about fish oil. Nutrition, 17, (2), 158-160. (doi:10.1016/S0899-9007(00)00569-4).
Thies, F., Nebe-von-Caron, G., Powell, J.R., Yaqoob, P., Newsholme, E.A. and Calder, P.C. (2001) Dietary supplementation with γ-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. Journal of Nutrition, 131, (7), 1918-1927.
Sadeghi, S., Wallace, F. and Calder, P. (1999) Dietary lipids modify the cytokine response to bacteria lipopolysaccharide in mice. Immunology, 96, (3), 404-410. (doi:10.1046/j.1365-2567.1999.00701.x). (PMID:10233721).
Yahqoob , P., Newsholme, E.A. and Calder, P.C. (1994) The effect of dietary manipulation on rat lymphocyte subsets and proliferation. Immunology, 82, (4), 603-610.
Calder, P.C., Bevan, S.J. and Newsholme, E.A. (1992) The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism. Immunology, 75, (1), 108-115.
Goodwin, G.M., Cowen, P.J., Fairburn, C.G., Parry-Billings, M., Calder, P.C. and Newsholme, E.A. (1990) Plasma concentrations of tryptophan and dieting. British Medical Journal , 300, (6738), 1499-1500.

Book

Calder, P.C. Scientific Advisory Committee on Nutrition (SACN) (2010) Iron and health, Norwich, GB, The Stationery Office, 360pp.

Book Section

Calder, P.C. (2013) Nutritional benefits of omega-3 fatty acids. In, Jacobsen, C., Skall Nielsen, N., Frisenfeldt Horn, A. and Moltke Sorensen, A-D. (eds.) Food Enrichment with Omega-3 Fatty Acids. Cambridge, GB, Woodhead Publishing, 3-26. (Woodhead Publishing Series in Food Science, Technology and Nutrition, 252).
Calder, P.C. (2013) Omega 3 polyunsaturated fatty acids. In, Brahmachari, Goutam (ed.) Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds. Boca Raton, US, CRC Press, 197-209.
Calder, P.C. (2013) Dietary fats and inflammation. In, Garg, M.L. and Wood, L.G. (eds.) Nutrition and Physical Activity in Inflammatory Diseases. Wallingford, GB, CAB International, 23-45.
Calder, P.C. (2013) Inflammation: an introduction. In, Garg, M.L. and Wood, L.G. (eds.) Nutrition and Physical Activity in Inflammatory Diseases. Wallingford, GB, CAB International, 1-22.
Calder, Philip C. (2013) Long-chain fatty acids and inflammatory processes. In, Calder, Philip C. and Yaqoob, Parveen (eds.) Diet, Immunity, and Inflammation. Oxford, GB, Woodhead, 457-483.
Calder, P.C. (2013) Omega-3 fatty acid deficiency and rheumatoid arthritis. In, McNamara, R.K. (ed.) The Omega-3 Fatty Acid Deficiency Syndrome. New York, US, Nova, 193-212.
Calder, P.C. (2013) Marine omega-3 polyunsaturated fatty acids and rheumatoid arthritis. In, Watson, R.R. and Preedy, V.R. (eds.) Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases. San Diego, US, Academic Press, 113-132.
Calder, P.C. (2012) Nutrition and inflammatory processes. In, Ross, A.C., Caballero, B., Cousins, R.J., Tucker, K.L. and Ziegler, T.R. (eds.) Modern Nutrition in Health and Disease. Baltimore, US, Wolters Kluwer/Lippincott Williams and Wilkins, 837-848.
Calder, P.C. (2012) Omega-6 and omega-3 polyunsaturated fatty acids and inflammatory bowel diseases. In, Watson, R.R. and Preedy, V.R. (eds.) Bioactive food as Dietary Interventions for Liver and Gastrointestinal Disease. San Diego, US, Academic Press, 55-79.
Calder, P.C. (2012) Omega-6 and omega-3 polyunsaturated fatty acids and inflammatory processes. In, Roy, S., Bagchi, D. and Raychaudhuri, S.P. (eds.) Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions. Boca Raton, US, CRC Press, 305-321.
Calder, P.C., Yaqoob, P. and Erdman, J.W. (2012) Nutrient regulation of the immune response. In, MacDonald, I.A. and Zeisel, S.H. (eds.) Present Knowledge in Nutrition. Ames, US, Wiley-Blackwell, 688-708.
Calder , Philip C. (2012) Nutrition – links to the immune system. In, Rippe, James M. (ed.) Encyclopedia of Lifestyle Medicine and Health. Los Angeles, US, Sage, 750-755.
Calder , Philip C. and Grimble, R.F. (2011) Nutrients that influence inflammation and immunity: omega-3 fatty acids. In, Sobotka, L. (ed.) Basics of Clinical Nutrition. 4th edition. Praha, CZ, Galen, 292-299.
Calder, P.C., Kremmyda, L.S., Vlachava, M., Noakes, Paul and Miles, Elizabeth A. (2011) Papel de los acidos grasos en la programacion temprana del sistema inmunitario. In, Marcos, Ascension (ed.) Inmunonutricion: En La Salud Y La Enfermedad. , Medica Panamericana, 102-112.
Calder, P.C. (2011) Inmunonutricion en pacientes quirurgicos y en estado critico. In, Marcos, Ascension (ed.) Immunonutrition: En La Salud Y La Enfermedad. Madrid, ES, Editorial Medica Panamericana, 556-567.
Calder, P.C. (2011) Omega-3 polyunsaturated fatty acids in human nutrition. In, Herrmann, Wolfgang and Obeid, Rima (eds.) Vitamins in the Prevention of Human Diseases. Berlin, DE, Walter de Gruyter, 629-643.
Yaqoob, Parveen and Calder, Philip C. (2010) The immune and inflammatory systems. In, Lanham-New, Susan A., Macdonald, Ian A. and Roche, Helen M. (eds.) Nutrition and Metabolism. 2nd Edition. Oxford, GB, Wiley, 312-338. (The Nutrition Society Textbook Series).
Calder, P.C. (2010) Polyunsaturated fatty acids, inflammatory processes and rheumatoid arthiritis. In, Horwitz, Randy and Muller, Daniel (eds.) Integrative Rheumatology, Allergy, and Immunology. New York, US, Oxford University Press, 23-46.
Sibjen, J.W.C., Boehm, G. and Calder, P.C. (2010) Fatty acids in immunomodulation: role in disease prevention and causation. In, Fatty Acids in Health Promotion and Disease Causation. Urbana, US, AOCS Press, 545-584.
Calder , Philip C. (2010) Fatty acids and inflammation – the role of dietary fatty acids in the modulation of intestinal inflammation. In, Cabre, E. and Gassull, M.A. (eds.) Nutritional Therapy in Inflammatory Bowel Disease. Maidenhead, GB, Abbott , 105-122.
Calder, P.C. (2010) Omega-3 fatty acids and inflammatory processes in the context of cardiovascular disease. In, Omega-3 Fatty Acids and Cardiovascular Disease. Bremen, DE, Unimed Science, 23-33. (Submitted).
Calder, Philip C. (2009) Polyunsaturated fatty acids, inflammation, and inflammatory disease. In, Kendall-Tackett, Kathleen (ed.) The Psychoneuroimmunology of Chronic Disease: Exploring the Links Between Inflammation, Stress, and Illness. Washington, US, American Psychological Association, 77-109.
Yaqoob, P., Tricon, S., Burdge, G.C. and Calder, P.C. (2006) Conjugated linoleic acid (CLAs) and health. In, Williams, C. and Buttriss, J. (eds.) Improving the Fat Content of Foods. Cambridge, UK, Woodhead, 182-209.
Yaqoob, P., Trcon, S., Burdge, G.C. and Calder, P.C. (2006) Conjugated linoleic acids (CLAs) and health. In, Williams, Christine and Buttriss, Judith (eds.) Improving the Fat Content of Foods. Cambridge, GB, Woodhead Publishing & Chemical Rubber Company Press, 182-209. (Woodhead Publishing Series in Food Science, Technology and Nutrition, 118).
Grimble, R.F., Calder, P.C., Gallagher, P.J., Garry, J., Howell, W. M., Rerkasem, K., Shearman, C. P., Thies, F. and Williams, J. (2006) Association of pro- and anti- inflammatory cytokine genetypes with the response of advance atherosclerotic plaque composition to dietary n-3 and n-6 polyunsaturated fatty acid supplementation. In, Teale, M.C. (ed.) Omega 3 Fatty Acid Research. New York, USA, Nova Science, 65-82.
Burdge, Graham C. and Calder, Philip C. (2006) Lipid metabolism: relevance to developmental origins of health and disease. In, Gluckman, Peter and Hanson, Mark (eds.) Developmental Origins of Health and Disease. Cambridge, UK, Cambridge University Press, 159-177.
Calder, Philip C. and Burdge, Graham C. (2004) Fatty acids. In, Nicolaou, Anna and Kokotos, George (eds.) Bioactive Lipids. Bridgwater, GB, The Oily Press, 1-36. (The Oily Press Lipid Library, 17).
Calder, P.C. (2004) Dietary lipids and immune function. In, Remacle, C. and Reusens, B. (eds.) Functional Foods, Ageing and Degenerative Disease. United Kingdom of Great Britain and Northern Ireland, GB, Woodhead Publishing, 349-393. (Woodhead Food Series , 102).
Jackson, Alan A. and Calder, Philip C. (2004) Severe undernutrition and immunity. In, Gershwin, M.Eric, Nestel, Penelope and Keen, Carl L. (eds.) Handbook of Nutrition and Immunity. London, GB, Humana Press, 71-106.
Calder, P.C. (2004) Polyunsaturated fatty acids and inflammation. In, Chandra, Ranjit Kumar (ed.) Nutrition and Immunology in the 21st Century. India, Republic of, IN, Tsar Press, 101-121.
Calder, P.C. and Yaqoob, P. (2003) Amino acids and immune function. In, Cynober, Luc A. (ed.) Metabolic and Therapeutic Aspects of Amino Acids in Clinical Nutrition. Second Edition. Boca Raton, US, Chemical Rubber Company, 284-306.
Calder, P.C. and Yaqoob, P. (2003) The immune and inflammatory systems. In, Gibney, Michale J., MacDonald, Ian and Roche, Helen (eds.) Nutrition and Metabolism. Oxford, GB, Wiley, 284-306.
Yaqoob, P. and Calder, P.C. (2003) Nutrition and immune function. In, Zempleni, J. and Daniel, H. (eds.) Molecular Nutrition. Wallingford, GB, Centre for Agricultural Bioscience International, 349-367.
Calder, P.C. and Yaqoob, P. (2003) Dietary fatty acids and macrophages. In, Gordon, Siamon (ed.) The Macrophage as a Therapeutic Target. Berlin, Springer, 173-192. (Handbook of Experimental Pharmacology 158).
Calder, P.C. (2003) Actualizacion en nutricion, immunidad e infeccion. In, Acidos Grasos Poliinsaturados, inflamacion e Immunidad. Madrid, CO, Medica Panamerica, 31-39.
Calder, P.C. and Field, C.J. (2002) Fatty acids, inflammation and immunity. In, Calder, P.C. (ed.) Nutrition and Immune Function. Wallingford, GB, Commonwealth Agricultural Bureaux International (CABI), 57-92.
Calder, P.C. and Newsholme, P. (2002) Glutamine and the immune system. In, Calder, P.C., Field, C.J. and Gill, H.S. (eds.) Nutrition and Immune Function. Guildford, GB, CABI, 109-132. (Frontiers in Nutritional Science, 1).
Calder, P.C. (2001) Nutrition and the immune system. In, Buttriss, Judith (ed.) Adverse Reactions to Food: the Report of the British Nutrition Foundation Task Force. London, GB, , 38-56.
Calder , P.C. (2001) The scientific basis for fish oil supplementation in rheumatoid arthritis. In, Ransley, J.K., Donnelly, J.K. and Read, N.W. (eds.) Food and Nutritional Supplements: Their role in Health and Disease. Berlin, DE, Springer Verlag, 175-197.
Calder, P.C. (2000) The effect of dietary fatty acids on the immune response and susceptibility to infection. In, Suskind, Robert M. and Tontisirin, Kraisid (eds.) Nutrition Immunity and Infection in Infants and Children. Philadelphia, US, Lippincott Williams & Wilkins, 137-172. (Nestlé Nutrition Workshop Series, Paediatric Program, 45).

Monograph

Calder, P.C. (2008) Omega-3 Fatty Acids: The good Oil? Brussels, BE, Institute Danone , 190pp.
 

Research

Research Interests

Professor Calder is interested in the interaction between nutrition and immune function especially as it relates to human health. The main focus of his research aims to identify the influence of dietary fatty acids on the immune and inflammatory systems and to understand the mechanisms of action of specific fatty acids. A combination of in vitro, ex vivo and in vivo approaches is used to study the functional responses of neutrophils, monocytes/macrophages and lymphocytes. A range of anti-inflammatory and immunomodulatory effects of the n-3 family of polyunsaturated fatty acids, particularly those found in fish oils, have been identified. It has been ascertained that these fatty acids work in part by antagonising the production and actions of arachidonic acid-derived eicosanoids and in part by eicosanoid-independent mechanisms. The findings of this research aid our knowledge of the health benefits of naturally-occurring fatty acids and provide information to underpin the design of nutritionally-based therapies for use in situations where components of the immune and inflammatory systems are under or over active.

Current projects investigate:

• The effect of increased intake of salmon by pregnant women on nutrient status and markers of immunity in newborn infants and their subsequent risk of allergic disease
• Dose and time dependence of incorporation of marine n-3 fatty acids into transport, functional and storage pools in humans
• The effect of chemical formulation of marine n-3 fatty acids on their bioavailability and incorporation into blood pools in humans
• The effect of marine n-3 fatty acids on inflammatory markers in lean and obese humans
• The mechanisms by which fatty acids exert anti-inflammatory actions (in vitro studies)
• Differential sensitivity to marine n-3 fatty acids according to genotype
• The effect of high dose marine n-3 fatty acids in patients with non-alcoholic fatty liver disease (in collaboration with Professor C Byrne and Professor G Clough)
• The effect of prebiotics on immune responses in older humans

Academic unit:  Human Development and Health

Research project

An investigation of the effects of moderate fish oil intake

Responsibilities

Postgraduate student supervision

1996 Nicola Jeffery DPhil
1997 Peter Sanderson DPhil
1998 Emma Sherrington DPhil
2000 Chris Donnellan PhD
2000 Fiona Wallace PhD
2001 Jennifer Garry PhD
2001 Samantha Kew PhD
2008 Caroline Childs PhD
2008 Hayati Yusof PhD
2010 Stella Kremmyda PhD
2011 Amy Lomax PhD
2011 Alison Fear PhD
2011 Maria Vlachava PhD
2011 Anna Stears DM

Current

Annette West PhD
Carolina Paras Chavez PhD
Albandri Alshathry PhD
Charlotte Pither DM

Faculty of Medicine

Member of Faculty International and Enterprise (FINE) Group
Member of Human Development and Health Academic Unit Executive Group
Co-leader of Nutrition & Metabolism research theme within the Human Development and Health Academic Unit

National and International responsibilities

Serve on the Council of the British Nutrition Foundation
Immediate Past-President of the International Society for the Study of Fatty Acids and Lipids (ISSFAL)
Serve on the Board of Directors of European Neutraceuticals Association
Associate Editor of Clinical Science
Associate Editor of Lipids
Associate Editor of Nutrition Research
Member of the Editorial Board of:
• Annals of Nutrition and Metabolism
• Biochimica et Biophysica Acta Molecular & Cell Biology of Lipids
• Clinical Nutrition
• European Journal of Nutrition
• Nutrition
• Prostaglandins Leukotrienes and Essential Fatty Acids
Section Editor (“Lipid metabolism & therapy”) for Current Opinion in Clinical Nutrition and Metabolic Care
Chaired several ILSI Europe Expert Groups including “Chronic Low Grade Inflammation in Metabolic Syndrome” and “Biomarkers of Inflammation” that reported in 2011 and 2012 respectively.

Teaching Responsibilities

Personal tutor.

BM5 and BM4. Delivers lectures on lipids and lipoproteins.

MMedSci. Offers laboratory projects.

BSc Biomedical Science. Co-ordinates one module. Delivers lectures on omega-3 fatty acids, vitamin D, diet and cardiovascular disease, immunonutrition, and gut health.

Contact

Professor Philip Calder
Faculty of Medicine
University of Southampton
IDS Building
Mailpoint 887 Southampton General Hospital
Tremona Road
Southampton SO16 6YD

Email: pcc@southampton.ac.uk

Room Number: SGH/CO5/MP887