About
Dr Salah Mansour is Associate Professor within Medicine at the University of Southampton. He leads a research group that employs a multidisciplinary approach to study the biological functions of CD1 molecules and their “unconventional” lipid reactive T cells. This has broad relevance to human diseases, including tuberculosis, cancer, and autoimmune conditions.
His lab combines basic interdisciplinary and translational studies that aim to improve our understanding of CD1 mediated immunity to help develop novel therapeutic targets and diagnostics for patient benefit. Current active funding is from HEFCE, CRUK, MRC, IfLS and PHE.
He has developed strong collaborations with computational and synthetic chemists, structural biologists, and with tuberculosis and cancer clinicians. He also has strong links with Public Health England Porton Down (Dr Sally Sharpe), King’s College London, The Francis Crick Institute, and the Africa Research Institute in Durban.
Research
Research groups
Research interests
- Unconventioanl T cells in health and disease
- CD1 group 1 restricted T cell immunity
- Structural and molecular mechainsms of CD1 lipid antigen presentation
- iNKT cells in human disease
Research projects
Active projects
Sponsor: Medical Research Council
Researchers:
Sponsor: Cancer Research UK
Completed projects
Researchers:
Researchers:
Sponsor: Wessex Medical Research
Researchers:
Sponsor: Cancer Research UK
Researchers:
Sponsor: Diabetes UK
Publications
26 publications
Page 1 of 3
Matthew D. Blunt, Hayden Fisher, Ralf B. Schittenhelm, Berenice Mbiribindi, Rebecca Fulton, Sajida Khan, Laura Espana-Serrano, Lara V. Graham, Leidy Bastidas-Legarda, Daniel Burns, Sophie M.S. Khakoo, Salah Mansour, Jonathan W. Essex, Rochelle Ayala, Jayajit Das, Anthony W. Purcell & Salim I. Khakoo,
2024, Science Advances, 10(34)
Type: article
Hannah Schiff, Naomi F. Walker, Cesar Ugarte-Gil, Marc Tebruegge, Spiros D. Garbis, Antigoni Manousopoulou, Salah Mansour, Pak Ho Wong, Gabrielle Rockett, Paolo Piazza, Mahesan Niranjan, Andres F. Vallejo, Christopher H. Woelk, Robert J. Wilkinson, Liku B. Tezera, Diana Garay Baquero & Paul Elkington,
2024, JCI Insight, 9(8)
Type: article
Abigail L. Hay, James Birch, Shirley Ellis, Daniel Burns, Salah Mansour, Salim I. Khakoo & John A. Hammond,
2023, Veterinary immunology and immunopathology, 263
Type: article
Alex Look, Daniel Burns, Ivo Tews, Ali Roghanian & Salah Mansour,
2023, Frontiers in Immunology, 14
Type: review
Mohamed Ahmed, Jared Mackenzie, Liku Bekele Tezera, Robert Krause, Barry Truebody, Diana Garay Baquero, Andres Vallejo Pulido, Katya Govender, John Adamson, Hayden Fisher, Jonathan W. Essex, Salah Mansour, Paul Elkington, Adrie J. C. Steyn & Alasdair Leslie,
2022, Communications Biology, 5(1317)
Type: article
Liku B. Tezera, Magdalena K Bielecka, Paul Ogongo, Naomi F. Walker, Matthew Ellis, Diana J. Garay-Baquero, Kristian Thomas, Michaela T. Reichmann, David A. Johnston, Katalin Andrea Wilkinson, Mohamed Ahmed, Sanjay Jogai, Suwan N. Jayasinghe, Robert J. Wilkinson, Salah Mansour, Gareth J. Thomas, Christian H. Ottensmeier, Alasdair Leslie & Paul T. Elkington,
2020, eLife, 9
DOI: 10.7554/eLife.52668
Type: article
Liku Bekele Tezera, Salah Mansour & Paul Elkington,
2019, American Journal of Respiratory and Critical Care Medicine, 201(4)
Type: review
D. Kennedy, M.A. Khan, C.J. Magee, S. M. Jones, D. Mason, M. Saunders, A. Jackson, T. Fletcher, S. Rahman, K. Lee, J. Heath, P. J. Needham, C. B. Tang, J. B. Cowley, W. M. Ho, D. Menzies, J. Reed, S. Khan, C. Zhang, S. J. Robinson, M. J. Jones, R. V. Dave, E. Jones, S. Singh, T. R. Wilson, S. T. Rao, L. Gould, A. Chambers, S. J. Robinson, R. Shah, M. Hughes, C. Jelley, M. Silva, A. Hussain, M. A. Ghazanfar, N. F. Watson, A. R. Dennison, R. P. Jones, S. Mansour, A. Khan, S. R. Smith, J. Chang, M. Lewis, G. P. Roberts, L. Gould, A. Chambers, K. Seymour, S. J. Robinson, H. Hawkins, P. V. Gallagher, A. Reid, P. Wood, J. Martin, A. Chambers, S. J. Mercer, S. Tate, S. Sinha, S. Khan, A. Hussain, V. Bhattacharya, C. Jackson, S. Basu, M. Akhtar, P. Kumar, M. Haque, S. Patel, C. P. Wood, D. Bradley, D. Lindsay, F. Noble, P. Turner, S. V. Williams, G. H. Jones, S. R. Smith, A. Hargreaves, M. A. Khan, A. Hussain, J. Porter, N. A. Jennings, S. Ali, H. Ali, R. Lane, Z. Hamady, A. R. Prasad, A. Patel, J. P. Byrne, K. L. Pearson, J. Davies, A. Macdonald, J. A. Nicholson, K. Newton, J. Barnes, K. Patel, C. Yao, S. F. Farag, M. F. Hamdan, M. Giles, N. A. Hirst, G. W. Taylor, R. L. Thompson, C. Warren, S. Martin, P. Davey, C. Jones, A. Harris, S. Dawson, G. Thomas, S. Mckenzie, A. D. Hill, J. T. Cassidy, A. D. Hill, S. Martin, K. S. Cross, F. Cooke, J. O. Murphy, I. Ahmed, J. Buchan, A. M. Khalil, S. Gibson, A. J. Grant, M. A. Jones, C. M. Sutton, C. R. Carter, D. I. Hunter, A. J. Watson, C. H. Richards, E. Harrison, M. S. Wilson, S. P. Bennett, C. L. Rutherford, A. K. Mirza, T. Ahmed, T. H. Brown, D. J. Stewart, A. L. Baker, C. Lo, A. Ali & J. A. Nicholson,
2019, World Journal of Surgery, 43(8), 1928–1934
Type: article
Edward Barton, Yifang Gao, Darran Ball, Katy Fidler, Nigel Klein, Nigel Curtis, Vanessa Clifford, Ben G. Marshall, Andrew Chancellor, Salah Mansour, Paul Elkington & Marc Tebruegge,
2019, Annals of the American Thoracic Society, 16(6), 771 - 775
Type: article
Daisy Melandri, Iva Zlatareva, Raphaël A G Chaleil, Robin J. Dart, Andrew Chancellor, Oliver Nussbaumer, Oxana Polyakova, Natalie A. Roberts, Daniela Wesch, Dieter Kabelitz, Peter M. Irving, Susan John, Salah Mansour, Paul A. Bates, Pierre Vantourout & Adrian C. Hayday,
2018, Nature Immunology, 19(12), 1352–1365
Type: article
Teaching
I am BM4 Year Two assessment lead and Year Two deputy lead.
I am the Infection and Immunity module lead for the integrated PhD programme.
I teach on NATS3006 (Drugs of the future, desinging a magic bullet).
External roles and responsibilities
Name:
Cholesteryl-esters, new ligands for CD1c autoreactive T cells
Role:
Speaker
Year:
2016
Name:
CD1c autoreactive T cell in human TB infection
Role:
Co-author
Year:
2021
Name:
Unconventional T cells in TB
Role:
Speaker
Year:
2021