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Research project

CCP4: Advanced integrated approaches to macromolecular structure determination

Staff

Lead researchers

Professor Ivo Tews

Professor

Research interests

  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
  • Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Connect with Ivo

Email: Ivo.Tews@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Successful sample preparation for serial crystallography experiments
John H. Beale, Rachel Bolton, Stephen A. Marshall, Emma V. Beale, Stephen B. Carr, Ali Ebrahim, Tadeo Moreno-Chicano, Michael A. Hough, Jonathan A.R. Worrall, Ivo Tews & Robin L. Owen, 2019, Journal of Applied Crystallography, 52(Pt 6), 1385-1396
DOI: 10.1107/S1600576719013517
Type: article