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Professor Martin Feelisch MSc, PhD

Professor of Experimental Medicine and Integrative Biology

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Martin is Professor of Experimental Medicine and Integrative Biology within Medicine at the University of Southampton.

In biology, a finite number of regulatory modules and organising principles suffice to support life and are used by microbes, plants and mammals alike. As a Systems Biologist (with a predilection toward evolutionary thought and a knack for analytical chemistry) I am interested in unraveling the significance of nitric oxide and sulfur in its various forms for human physiology. Specifically, I aim to understand how their production and availabilities are regulated in the face of rapidly changing demands as a function of nutrient and oxygen supply, physical activity and interaction with the environment; and – above all - how this is orchestrated at the cellular, organ and whole body level.

After the study of pharmacy Martin earned his PhD in pharmacology from the Heinrich-Heine University in Dusseldorf in 1988. He was appointed to the Personal Chair of Experimental Medicine & Integrative Biology at Southampton University in April 2012, following a number of other senior research positions in both academia and industry in the USA and Europe.

Appointments held






Research interests

Martin has a long-standing interest in analytical chemistry, cardiovascular pharmacology, nutrition and metabolism, disease mechanisms, and the chemical biology of nitric oxide (NO) and nitroxyl (HNO), and has received several awards/honors in recognition of his research achievements in these areas. His more recent interests focus on the physiological significance of nitros(yl)ation reactions and the role of NO storage forms in blood and tissues; photobiology; biomarkers of cardiovascular disease and adaptation to hypoxia; hypoxic signalling and altitude physiology; regulation of mitochondrial function and redox signalling; and systems-based approaches to assessing the role of sulfide as well as nitrite, nitrate and other NO-related products in vivo. Work in his laboratory is both hypothesis- and curiosity-driven and includes basic as well as translational research projects in all of the above areas.

Research group(s)

Clinical and Experimental Sciences Academic Units

Postgraduate Supervision
  • Supervision of 6 MMedSc, 1 BMedSc, 2 MD, and 8 PhD students (Germany, USA, UK)
  • Current supervision of 1 Masters and 3 PhD students.
External Assessor/Examiner/Opponent
  • 2002 Neesha Suvarna (University of Tennessee)
  • 2007 Eliza Tsou (University of Buffalo)
  • 2008 Sarah Fox (University of Edinburgh)
  • 2008 Megan Mowbray (University of Edinburgh)
  • 2012 Rasmus Aamand Olesen (Aarhus University)
  • 2014 Johanna van Langen (Antwerp University)
  • 2015 Anne-Roos S Frenay (University of Groningen) 
Honours and Service
  • 1990 Fritz-Külz-Prize (German Society for Exp & Clin Pharmacology and Toxicology)
  • 1990-today ad hoc reviewer for >20 scientific journals
  • 1992-today Organization, co-organisation and member of Scientific Advisory Boards of >10
    international scientific meetings and workshops (30-650 participants)
  • 1993-97 Editorial Board, Endothelium
  • 1995- Co-Founder and Director of the "Nitric Oxide Society"
  • 1995-today Editorial Board, Nitric Oxide Chemistry and Biology
  • 1999-today Reviewer for national and international grant funding bodies (incl NIH, Wellcome
    Trust, MRC, The Royal Society, SFI, DFG, and FWF)
  • 2005-09 Associate Editor, British Journal of Pharmacology
  • 2009 External Reviewer and Member of Site-Visit Team, Trinity College School of Pharmacy, Dublin, Ireland
  • 2011 Chair, Gordon Research Conference on Nitric Oxide
  • 2011-today Member, Xtreme Everest Scientific Strategy Group
  • 2013-today Member, NIHR Wellcome Trust Early Phase Safety Committee
  • 2014-today Member, Scientific Advisory Board, AOBiome, Cambridge, MA
  • 2015-today Editorial Board, Pharmacological Research 



Book Section(s)

Professor Martin Feelisch
Faculty of Medicine, University of Southampton, Southampton General Hospital, Mailpoint 801, South Academic Block, Tremona Road, Southampton, SO16 6YD or Faculty of Medicine, University of Southampton, Building 85, Life Sciences Building, Highfield Campus, Southampton, SO171BJ

Room Number: SGH/LF80/MP810

Telephone: (023) 8120 6891

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