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PsychologyOur news, events & seminars

Benefits and Risks of ADHD Medication: A Pharmacoepidemiologic Perspective Seminar

11:00 - 12:00
7 March 2019
University of Southampton, Highfield Campus, Building 6, Room 1077 (L/T A)

For more information regarding this seminar, please telephone Sue McNally on 02380 595150 or email .

Event details

Visiting speaker hosted by Dr Julie Hadwin and Dr Samuele Cortese, Centre for Innovation in Mental Health (CiMH)

Randomized controlled trials (RCTs) suggest that ADHD medication has beneficial short-term effects on symptoms of ADHD, and some co-occurring disorders. RCTs of ADHD medication have serious limitations, however, including the inability to generalize to individuals with serious comorbid problems, study rare-but-serious outcomes, and adequately examine long-term outcomes.Therefore, there is a critical need to more precisely identify the benefits and risks of ADHD medication, particularly with samples and designs that can explore rare outcomes.

The presentation will provide examples of how the analyses of large-scale health insurance claims datasets in the United States and national registry data (e.g., in Sweden) can help specify the benefits and risks of ADHD medication when using advanced research designs. In particular, the talk will describe how the use of within-individual comparisons (i.e., using periods in which an individual is not dispensed medication as the comparison for periods in which he/she was dispensed medication) can help elucidate the associations between ADHD medication and numerous outcomes, including serious substance use problems, motor vehicle accidents, depression/suicide attempts, seizures, and accidents/injuries.

Speaker information

Professor Brian D'Onofrio, Indiana University Bloomington. Professor D'Onofrio's areas of study are Clinical Science and Developmental Psychology. His research includes Developmental Psychopathology, Behaviour Genetics, Family Systems and Pharmacoepidemiology. His research is rooted in the field of developmental psychopathology, exploring the causes and treatments of child and adolescent psychopathology through three main approaches: quasi-experimental designs, longitudinal analyses, and intervention studies.

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