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The University of Southampton
Southampton Neuroscience Group

Dementia - A National Symposium Event

30 - 31 May 2013
Open University

Event details

You are cordially invited to this Symposium on Dementia at the Open University in Milton Keynes (30-31 May), at which leading UK clinical and non-clinical scientists will be presenting their work. The event, sponsored by the Alzheimer's Society and Alzheimer's Research UK, offers opportunities for knowledge exchange, networking and continuous professional development, and aims to raise further awareness and understanding of dementia. It brings together key researchers from across the UK who are working in the field of dementia, highlights the range of research perspectives that are contributing to the understanding of dementia, and provides a forum for discussion and exchange of ideas within and across disciplines. It will showcase how UK-led research and investigators are contributing towards this endeavour on an international arena. We are delighted to have such a distinguished line-up of speakers at the event. Baroness Susan Greenfield CBE will also be joining us on the evening of 30 May to speak on ‘the challenges and impact of dementia research’ at the symposium dinner.


Dementia - A National Symposium, Open University, 30-31 May 2013

Programme (Schedule for Day 1)
Thursday 30 May 2013
08.00 Registration, coffee and pastries
09.10 Welcome and introduction - Dr Payam Rezaie, The Open University

Opening Session
09.20 Prof Steven Rose, The Open University
09.30 Dr Doug Brown, Director of Research & Development, Alzheimer's Society
09.40 Dr Eric Karran, Director of Research, Alzheimer's Research UK

Session 1: Global Perspectives - The Impact of Dementia
Chair: Prof Steven Rose
09.50 Prof Martin Prince, Institute of Psychiatry, King's College London. The global burden of dementia (focus on epidemiology and risk factors)
10.30 Prof Sube Banerjee, University of Sussex. Quality of life and the impact of dementia (focus on social and cultural aspects)

Session 2: Diagnosis and Assessment
Chair: Prof Martin Prince
11.10 Dr Peter Bowie, Sheffield Health & Social Care NHS Foundation Trust. Differential diagnosis and clinical assessment of the dementias (including changes introduced in DSM-V)
11.50 Prof Robin Morris, Institute of Psychiatry, King's College London. Neuropsychological assessment of dementia
12.30 Lunch

Session 3: Genetics and Neurobiology 1
Chair: Prof Sube Banerjee
13.30 Prof Julie Williams, University of Cardiff. Identifying and understanding genes which increase the risk of developing Alzheimer's disease and other dementias
14.10 Prof James Nicoll, University of Southampton. Molecular pathogenesis and neuropathology of Alzheimer's disease (biology of A-beta, NFTs and their roles in AD pathogenesis)
14.50 Prof Paul Francis, King's College London, University of London. Neurochemistry of Alzheimer's disease and other dementias (neurochemical systems involved in learning and memory)
15.30 Coffee

UK Research Highlights Session A (Recent Findings, New and Emerging Areas)
Panel: Professors Julie Williams, Paul Francis and Robin Morris
16.00 Prof Michael Stewart, The Open University. Synaptic plasticity in learning and memory - EU Framework ‘Promemoria' and ‘Memstick' projects
16.15 Dr Rita Guerreiro, UCL Institute of Neurology. New risk gene (TREM2 variant) suggests immune response plays a key role in AD
16.30 Dr Roxana Carare, University of Southampton. A role for the susceptibility gene APOE in AD - linking APOE e4 to clearance of beta amyloid
16.45 Dr Christopher Kobylecki, University of Manchester. Amyloid imaging of AD versus FTD
17.00 Dr Josephine Barnes, UCL Institute of Neurology. Predicting brain atrophy in AD - white matter disease and CSF markers of AD pathology
17.15 Prof Margaret Esiri, University of Oxford. Cognitive reserve, cortical plasticity and resistance to Alzheimer's disease
17.30 Dr Ilona Roth, The Open University. A comprehensive profile of awareness in early stage dementia - the MIDAS project
17.45 Symposium discussion (Day 1) led by panel and session chairs
18.00 Close of meeting (Day 1)
18.00 Social Event Wine Reception. Venue: Berrill Ground Floor, Open University
19.00 Symposium Dinner Guest Speaker: Baroness Susan Greenfield CBE. The challenges and impact of dementia research

Programme (Schedule for Day 2)
Friday 31 May 2013
08.30 Registration

Session 4: Genetics and Neurobiology 2
Chair: Prof James Nicoll
09.00 Prof Stuart Pickering-Brown, University of Manchester. Frontotemporal dementia: clinical characteristics, diagnosis, genetics and molecular pathology
09.40 Dr Johannes Attems, University of Newcastle. Dementia with Lewy bodies: insights into pathology, pathogenesis and treatment
10.15 Coffee

Session 5: Interventions 1
Chair: Prof Clive Holmes
10.40 Prof John Zajicek, Universities of Exeter and Plymouth. Clinical trials in dementia - the evidence base for treatment of the dementias
11.20 Prof Gordon Wilcock, University of Oxford. Established and emerging pharmacotherapy for the treatment and prevention of dementia
12.00 Dr Eric Karran, Alzheimer's Research UK. The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics (latest developments and future research)
12.40 Lunch

Session 6: Interventions 2
Chair: Prof Gordon Wilcock
13.30 Prof Clive Holmes, University of Southampton. The biological and clinical outcomes of immunotherapy and the role of inflammation in the development of Alzheimer's disease
14.10 Prof Martin Orrell, UCL Mental Health Sciences Unit, University of London. Cognitive stimulation therapy and psychosocial interventions for dementia
14.50 Prof Jan Oyebode, University of Bradford. Management of dementia - innovations in care and support
15.30 Coffee

UK Research Highlights Session B (Recent Findings, New and Emerging Areas)
Panel: Professors John Zajicek, Martin Orrell and Stuart Pickering-Brown
16.00 Dr Naheed Mukadam, UCL Mental Health Sciences Unit. The experience of dementia across ethnic groups - improving access to services
16.15 Dr Sebastian Crutch, UCL Institute of Neurology. Investigating posterior cortical atrophy
16.30 Prof Kevin Morgan, University of Nottingham. Biomarkers as clues to early AD diagnosis - a panel approach
16.45 Dr Magdalena Sastre, Imperial College London. Investigating the link between AD and type 2 diabetes
17.00 Dr Ruth Peters, Imperial College London. Blood pressure, smoking and alcohol use - association with vascular dementia
17.15 Dr Atticus Hainsworth, St George's, University of London. Experimental models of vascular dementia
17.30 Symposium discussion (Day 2) led by panel and session chairs
17.45 Closing Speaker Prof Michael Stewart, The Open University
18.00 Close of Meeting (Day 2)


Registration Information

Registration is FREE for all scientific sessions but places are limited and are being allocated promptly, so please do book your place by completing the online registration form at the earliest opportunity (you can do this by clicking on the tab to the bottom right of the flyer). Registration closes on 17 May (or earlier if all places have been allocated prior to this date). If you have any queries, please contact and one of the administrative team would be happy to help. We would be delighted if you are able to join us and look forward to welcoming you to the event.

To register go to



Sponsored by the British Neuroscience Association

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