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The University of Southampton
Clinical Ethics and Law at Southampton

Professional views about aCGH testing

Array-comparative-genomic-hybridization (aCGH) is an advanced genomic test which detects sub-microscopic deletions and duplications in the genome not identified via traditional methods (karyotyping). It is commonly used in children with developmental delay/intellectual disability and/or congenital malformations.

Professional views about aCGH testi

In the prenatal setting, it allows a higher detection rate and shorter turnaround time compared to karyotyping.

However, the test can also reveal findings that are:-

Little empirical data exists on health care professionals’ (HCPs’) views about these issues.

This study aimed to explore the views of UK healthcare professionals (HCPs) about:-

Using Q-methodology, which combines qualitative and quantitative approaches, the views of 45 HCPs (Genetic-health-professionals, lab-scientists, fetal-medicine-experts) were explored.

The discussion around how participants have ranked statements has provided us with a valuable insight into the ethical issues that healthcare professionals think should be considered in introducing such a new test.

Shiri Shkedi-Rafid was the lead researcher

This project is now closed for recruitment

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