Molecular Control of RNA Metabolism Seminar
- Time:
- 12:00
- Date:
- 9 April 2014
- Venue:
- Building 27, Room 2001 Chemistry Highfield Southampton SO17 1BJ
For more information regarding this seminar, please email Dr Jon Watts at J.K.Watts@soton.ac.uk .
Event details
Dr Anastatia Callaghan presents a seminar as part of the MDT section seminar series
Molecular Control of RNA Metabolism
Post-transcriptional gene regulation mechanisms in bacteria are
central in allowing responses to environmental stresses and in controlling
pathogenic virulence. For example, RNases provide a means of regulation
through the processing and degradation of the RNA population, whilst the
pairing of small non-coding RNAs (sRNAs) with their mRNA targets, mediated
by the RNA chaperone protein Hfq, modulates mRNA translation. My talk will
provide an overview of our recent findings investigating the interplay of V.
cholerae sRNAs and Hfq, before concluding with our recent findings of a
communicative link between a molecule of central metabolism and activity
regulation of a bacterial RNase.
Speaker information
Dr Anastasia Callaghan, University of Portsmouth. Reader in Biochemistry & Molecular Biophysics