Through our internationally recognised Developmental Origins of Health and Disease Centre we incorporate the work of the Medical Research Council Lifecourse Epidemiology Unit, the NIHR Nutrition Biomedical Research Centre and the University's Institute of Developmental Sciences.
The HDH Academic Unit focuses on world leading research into human development and the mechanisms that underlie its impact on health and disease. HDH scientists, clinicians and students work in the laboratory, office, lecture theatre and clinic to understand the science, deliver excellence in teaching, and develop new treatments to make a difference. Many of our projects work on early onset life events including genetic and environmental influences affecting chronic lifelong disorders.
Through our internationally recognised Developmental Origins of Health and Disease Centre we incorporate the work of the Medical Research Council Lifecourse Epidemiology Unit, the NIHR Nutrition Biomedical Research Centre and the University's Institute of Developmental Sciences. Our acclaimed researchers are working with the World Health Organization, the United Nations and other international government and non-government organisations to reduce the burden of non-communicable disease in both developed and developing countries.
We have extensive links with industry, the private sector and University Hospital Southampton in joint initiatives such as the development of the Wessex Genome Medicine Centre to understand the impact of genome testing for patients with rare developmental disorders.
Using stem cells and biomaterials to treat chronic and acute bone fracture repair; researching the impact of vitamin D supplements in the mother and reduction of risk later on of osteoporosis as the child journeys through life.
Understanding embryo and placental health and the impact in child and adulthood.
The study of cardiovascular responses across the life course – to identify what influences healthy vasculature in later life.
Using new sequencing technologies for genomic stratification of disease and diagnosis to develop tailor-made drug targeting and medical management to progress personalised medicine.
Dissecting molecular mechanisms involved in gene function such as ... ion channels, RNA/splicing.
Optimisation of nutrition to prevent and understand the metabolism underpinning disease such as non-alcoholic fatty liver disease, a major problem in obesity.
Development of epigenetic biomarkers to provide early warning of at risk groups for lifelong disorders.
Determining the role of epigenomics in clinical diagnosis and understanding the genomic influences of gene expression using genetic imprinting as a model.
|Staff Member||Primary Position|
|Avan Aihie Sayer||Professor of Geriatric Medicine|
|Nigel Arden||Professor in Rheumatic Diseases|
|Janis Baird||Associate Professor of Public Health Medicine|
|Diana Baralle||Associate Professor and Consultant in Clinical Genetics|
|Mary Barker||Associate Professor in Psychology|
|Sheila Barton||Senior Statistician|
|Graham Burdge||Professor of Nutritional Biochemistry|
|Christopher Byrne||Professor of Endocrinology and Metabolism|
|Felino Cagampang||Associate Professor in Integrative Physiology|
|Philip Calder||Professor of Nutritional Immunology|
|Ying Cheong||Associate Professor Obstetrics and Gynaecology|
|Nicholas Clarke||Consultant Orthopaedic Surgeon|
|Jane Cleal||Lecturer in Epigenetics|
|Geraldine Clough||Professor of Vascular Physiology|
|David Coggon||Professor of Occupational and Environmental Medicine|
|Andrew Collins||Professor of Genetic Epidemiology and Bioinformatics|
|Cyrus Cooper||Director of the MRC Lifecourse Epidemiology Unit|
|Nick Cross||Professor of Human Genetics|
|Sarah Crozier||Senior Medical Statistician|
|Nick Curzen||Honorary Chair in Cardiac Electrophysiology|
|Justin Davies||Honorary Senior Clinical Lecturer|
|Jonathan Dawson||EPSRC Research Fellow|
|Elaine Dennison||Professor of Musculoskeletal Epidemiology and Honorary Consultant in Rheumatology|
|Judith Eckert||Associate Professor in Early Development|
|Christopher Edwards||Consultant Rheumatologist, University Hospital Southampton NHS Foundation Trust|
|Marinos Elia||Professor of Clinical Nutrition & Metabolism|
|Nicola Englyst||Associate Professor|
|Sarah Ennis||Professor of Genomics|
|Nicholas Evans||Lecturer in Bioengineering|
|Caroline Fall||Professor of International Paediatric Epidemiology|
|Catharine Gale||Professor of Cognitive Epidemiology|
|Keith Godfrey||Professor of Epidemiology and Human Development|
|Lucy Green||Associate Professor in Developmental Physiology|
|Mike Grocott||Professor of Anaesthesia and Critical Care Medicine|
|Mark Hanson||British Heart Foundation Professor of Cardiovascular Science|
|Nicholas Harvey||Professor of Rheumatology and Clinical Epidemiology|
|John Holloway||Professor of Allergy and Respiratory Genetics|
|Richard Holt||Professor in Diabetes and Endocrinology|
|Franchesca Houghton||Associate Professor in Stem Cells & Developmental Biology|
|Hazel Inskip||Deputy Director, MRC Lifecourse Epidemiology Unit|
|Alan Jackson||Professor of Human Nutrition|
|Patricia Jacobs||Honorary Professor of Human Genetics|
|Ngianga II Kandala||Medical Statistician|
|Kalyanaraman Kumaran||Clinical Scientist/Senior Lecturer|
|Wendy Lawrence||Associate Professor of Health Psychology|
|Rohan Lewis||Reader in Physiology|
|Karen A Lillycrop||Professor of Epigenetics|
|Ben MacArthur||Associate Professor in mathematics in the life sciences|
|Deborah Mackay||Professor of Medical Epigenetics|
|Nicholas Stephen Macklon||Professor of Obstetrics and Gynaecology|
|John Morgan||Honorary Professor of Cardiac Rhythm Management, Cardiology|
|Penelope Nestel||Principal Teaching Fellow|
|Marie-Louise Newell||Professor of Global Health (both in Faculty of Medicine and Faculty of Social, Human and Mathematical Sciences)|
|Richard Oreffo||Professor of Musculoskeletal Science|
|Clive Osmond||Medical Research Council Senior Scientist|
|Keith T Palmer||Professor of Occupational Medicine|
|Reuben J Pengelly||Research Fellow in Medical Genomics|
|Kirsten Poore||Lecturer in Physiology|
|Dieter Riethmacher||Associate Professor in Human Genetics|
|Graham Roberts||Professor and Honorary Consultant Paediatrician in Paediatric Allergy and Respiratory Medicine|
|Helen Roberts||Associate Professor and Honorary Consultant in Geriatric Medicine|
|Siân Robinson||Professor of Nutritional Epidemiology|
|Cliff Shearman||Professor of Vascular Surgery|
|William J Tapper||Senior Research Fellow in Genomic Informatics|
|Rahul Tare||Lecturer - Musculoskeletal Science and Bioengineering|
|Karen Temple||Professor of Medical Genetics|
|Christopher Torrens||Associate Professor in Physiology|
|Bas Van Rijn||Clinical Lecturer in Obstetrics and Gynaecology|
|Igor Vorechovsky||Principal Research Fellow|
|Karen Walker-Bone||Associate Professor in Occupational Rheumatology|
|David Wilson||Professor of Human Developmental Genetics|
|Stephen Wootton||Senior Lecturer in Human Nutrition|