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CONTRACT feasibility study publishes protocol in open access journal

Published: 15 May 2018

CONTRACT Study - CONservativeTReatment of Appendicitis in Children(feasibility): study protocol for a randomised controlled Trial

Hutchings et al. Trials (2018) 19:153


Currently, the routine treatment for acute appendicitis in the United Kingdom is an appendicectomy. However, there is increasing scientific interest and research into non-operative treatment of appendicitis in adults and children. While a number of studies have investigated non-operative treatment of appendicitis in adults, this research cannot be applied to the paediatric population. This protocol is for a feasibility study to test the clinical and cost effectiveness of non-operative treatment of acute uncomplicated appendicitis in children, as compared with appendicectomy.


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