Publications | Southampton Clinical Trials Unit

You can browse a selection of publications below or browse all publications in our ePrints repository.

Sort via:TypeorYear

Articles

Llewellyn, A., Buckle, L., Grieve, S., Birklein, F., Brunner, F., Goebel, A., Harden, R. N., Bruehl, S., Vaughan-spickers, N., Connett, R., & Mccabe, C. (2023). Delphi study to define core clinical outcomes for inclusion in a complex regional pain syndrome international research registry and data bank. Pain, 164(3), 543-554. https://doi.org/10.1097/j.pain.0000000000002729
Iflaifel, M., Sprange, K., Bell, J., Cook, A., Gamble, C., Julious, S. A., Juszczak, E., Linsell, L., Montgomery, A., & Partlett, C. (2023). Developing guidance for a risk-proportionate approach to blinding statisticians within clinical trials: a mixed methods study. Trials, 24, [71]. https://doi.org/10.1186/s13063-022-06992-5
Santer, M., Lawrence, M., Renz, S. M., Eminton, Z., Stuart, B., Sach, T., Pyne, S., Ridd, M. J., Muller, I., Francis, N. A., Soulsby, I., Thomas, K., Permyakova, N. V., Little, P., Muller, I., Nuttall, J., Griffiths, G., Thomas, K. S., & Layton, A. M. (2023). Effectiveness of spironolactone for women with acne vulgaris (SAFA) in England and Wales: pragmatic, multicentre, phase 3, double blind, randomised controlled trial. The BMJ, 381, e074349. [e074349]. https://doi.org/10.1136/bmj-2022-074349
Hall, N., Sherratt, F. C., Eaton, S., Walker, E., Chorozoglou, M., Beasant , L., Stanton, M. P., Corbett , H. J., Rex , D., Hutchings, N. J., Dixon, E., Crawley , E., Blazeby , J., Young, B., & Reading, I. (Accepted/In press). Patient centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children. BMJ Paediatrics Open, 7(1).
Johnson, L., Burridge, J., Ewings, S., Westcott, E., Gayton, M., & Demain, S. (2023). Principles into practice: an observational study of physiotherapists use of motor learning principles in stroke rehabilitation. Physiotherapy, 118, 20-30. https://doi.org/10.1016/j.physio.2022.06.002
Brandsma, J., Schofield, J. P. R., Yang, X., & U-BIOPRED Study Group (2023). Stratification of asthma by lipidomic profiling of induced sputum supernatant. The Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2023.02.032
Sri Ranjan, Y., Ziauddeen, N., Stuart, B., Alwan, N., & Cheong, Y. (2023). The role of parity in the relationship between endometriosis and pregnancy outcomes. Reproduction and Fertility, 4(1), [e220070]. https://doi.org/10.1530/RAF-22-0070
Shapanis, A., Jones, M. G., Schofield, J., & Skipp, P. (2023). Topological data analysis identifies molecular phenotypes of idiopathic pulmonary fibrosis. Thorax, 1-8. https://doi.org/10.1136/thorax-2022-219731
Greenwell, K., Sivyer, K., Howells, L., Steele, M., Ridd, M. J., Roberts, A., Ahmed, A., Lawton, S., Langan, S. M., Hooper, J., Wilczynska, S., Leighton, P., Griffiths, G., Sach, T., Little, P., Williams, H. C., Thomas, K. S., Yardley, L., Santer, M., & Muller, I. (2022). “Eczema shouldn’t control you; you should control eczema”: qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema. British Journal of Dermatology, [ljac115]. https://doi.org/10.1093/bjd/ljac115, https://doi.org/10.1093/bjd/ljac115
Miller, S., Yardley, L., Smith, P. W. F., Weal, M., Milton, A. MC., Stuart, B., Little, P., & Morrison, L. (2022). A digital intervention for respiratory tract infections (Internet Dr): process evaluation to understand how to support self-care for minor ailments. JMIR Formative Research , 6(1), [e24239]. https://doi.org/10.2196/24239
Torr, B., Jones, C., Choi, S., Allen, S., Kavanaugh, G., Hamill, M., Garrett, A., MacMahon, S., Loong, L., Reay, A., Yuan, L., Valganon Petrizan, M., Monson, K., Perry, N., Fallowfield, L., Jenkins, V., Gold, R., Taylor, A., Gabe, R., ... Turnbull, C. (2022). A digital pathway for genetic testing in UK NHS patients with cancer: BRCA-DIRECT randomised study internal pilot. Journal of Medical Genetics, 59(12), 1179-1188. https://doi.org/10.1136/jmg-2022-108655
Tse, M. M. Y., Ng, S. S. M., Lou, V., Lo, R., Cheung, D. S. K., Lee, P., & Tang, A. S. K. (2022). A dyadic pain management program for community-dwelling older adults with chronic pain: study protocol for a cluster randomized controlled trial. International Journal of Environmental Research and Public Health, 19(19), [12186]. https://doi.org/10.3390/ijerph191912186
Davies, A., Barrans, S., Burton, C., Mercer, K., Caddy, J., Chinnery, F., Day, L., Fernando, D., Ardeshna, K., Collins, G., Radford, J., Rule, S., Mcmillan, A., Johnson, P., & Griffiths, G. (2022). ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial. F1000Research, 9, [941]. https://doi.org/10.12688/f1000research.22318.1
Porter, C., Lester, J., Danson, S., Taylor, P., Sheaff, M., Rudd, R. M., Gaba, A., Busacca, S., Nixon, L., Gardner, G., Darlison, L., Poile, C., Richards, C., Jordan, P-W., Griffiths, G., & Casbard, A. (2022). Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): a randomised, phase 2 trial. EClinicalMedicine, 48, [101432]. https://doi.org/10.1016/j.eclinm.2022.101432
Mubangizi, V., McGrath, N., Kabakyenga, J. K., Muller, I., Stuart, B. L., Raftery, J. P., Natukunda, S., Ngonzi, J., Goodhart, C., & Willcox, M. L. (2022). Antenatal couples' counselling in Uganda (ACCU): study protocol for a randomised controlled feasibility trial. Pilot and Feasibility Studies, 8, [97]. https://doi.org/10.1186/s40814-022-01049-5
Lee, P. H., Tse, A. C. Y., Cheung, T., Do, C. W., Szeto, G. P. Y., So, B. C. L., & Lee, R. L. T. (2022). Bedtime smart device usage and accelerometer-measured sleep outcomes in children and adolescents. Sleep and Breathing, 26(1), 477-487. https://doi.org/10.1007/s11325-021-02377-1
Iflaifel, M., Partlett, C., Bell, J., Cook, A., Gamble, C., Julious, S., Juszczak, E., Linsell, L., Montgomery, A., & Sprange, K. (2022). Blinding of study statisticians in clinical trials: a qualitative study in UK clinical trials units. Trials, 23(1), [535]. https://doi.org/10.1186/s13063-022-06481-9
Durkin, K., Heetun, M. A., Ewings, S., Munday, R., Wootton, S., Turner, L., Copson, E., & Cutress, R. (2022). Body composition and chemotherapy toxicity in women with early breast cancer (CANDO-3): protocol for an observational cohort study. BMJ Open, 12(2), [e054412]. https://doi.org/10.1136/bmjopen-2021-054412
The RECOVERY Collaborative Group (2022). Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet (London, England), 399(10325), 665-676. https://doi.org/10.1016/S0140-6736(22)00163-5, https://doi.org/10.1016/S0140-6736(22)00163-5
Donovan-Banfield, I., Penrice-Randal, R., Goldswain, H., Rzeszutek, A. M., Pilgrim, J., Bullock, K., Saunders, G., Northey, J., Dong, X., Ryan, Y., Reynolds, H., Tetlow, M., Walker, L. E., FitzGerald, R., Hale, C., Lyon, R., Woods, C., Ahmad, S., Hadjiyiannakis, D., ... Fletcher, T. (2022). Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial. Nature Communications, 13(1), [7284]. https://doi.org/10.1038/s41467-022-34839-9
Cong, W., Chai, J., Zhao, L., Cabral, C., Yardley, L., Yao, G. L., Zhang, T., Cheng, J., Shen, X., Liu, R., Little, P., Stuart, B., Hu, X., Sun, Y-H., Oliver, I., Zheng, B., Lambert, H., & Wang, D. (2022). Cluster randomised controlled trial to assess a tailored intervention to reduce antibiotic prescribing in rural China: study protocol. BMJ Open, 12(1), [e048267]. https://doi.org/10.1136/bmjopen-2020-048267
Ho, K. H. M., Cheung, D. S. K., Lee, P. H., Lam, S. C., & Kwan, R. Y. C. (2022). Co-living with migrant domestic workers is associated with a lower level of loneliness among community-dwelling older adults: a cross-sectional study. Health and Social Care in the Community, 30(4), e1123-e1133. https://doi.org/10.1111/hsc.13520
Griffiths, G. (2022). CONFIRM trial: what is the real efficacy of second-line immunotherapy in mesothelioma? - Authors' reply. Lancet Oncology, 23(1), e14-e15. https://doi.org/10.1016/S1470-2045(21)00722-1
Afolabi, P. R., McDonnell, D., Byrne, C. D., Wilding, S., Goss, V., Walters, J., & Hamady, Z. Z. (2022). DEPEND study protocol: early detection of patients with pancreatic cancer - a pilot study to evaluate the utility of faecal elastase-1 and 13C-mixed triglyceride breath test as screening tools in high-risk individuals. BMJ Open, 12(2), [e057271]. https://doi.org/10.1136/bmjopen-2021-057271
Yardley, L., Morton, K., Greenwell, K., Stuart, B., Rice, C., Bradbury, K., Ainsworth, B., Band, R., Murray, E., Mair, F., May, C., Michie, S., Richards-Hall, S., Smith, P. W. F., Bruton, A., Raftery, J., Zhu, S., Thomas, M., McManus, R. J., & Little, P. (2022). Development and evaluation of digital interventions for hypertension and asthma in primary care: The DIPSS research programme including 2 RCTs. Programme Grants for Applied Research, 10(11). https://doi.org/10.3310/BWFI7321
Santer, M., Muller, I., Becque, T., Stuart, B., Hooper, J., Steele, M., Wilczynska, S., Sach, T. H., Ridd, M. J., Roberts, A., Ahmed, A., Yardley, L., Little, P., Greenwell, K., Sivyer, K., Nuttall, J., Griffiths, G., Lawton, S., Langan, S., ... Thomas, K. S. (2022). Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials. The BMJ, 379, e072007. [e072007]. https://doi.org/10.1136/bmj-2022-072007
Tse, A. C. Y., Lee, P. H., Zhang, J., Chan, R. C. Y., Ho, A. W. Y., & Lai, E. W. H. (2022). Effects of exercise on sleep, melatonin level, and behavioral functioning in children with autism. Autism, 26(7), 1712-1722. https://doi.org/10.1177/13623613211062952
Smyth, E., Cozens, K., Griffiths, D., Clark, K. L., Ewings, S., Petty, R., Underwood, T., Fitzgerald, R. C., Tanner, J., Giger, O., Anand, S., & Griffiths, G. (2022). ELEVATE - evaluating Temozolomide and Nivolumab in patients with advanced unresectable previously treated oesophagogastric adenocarcinoma with MGMT methylation: study protocol for a single arm phase II trial. BMC cancer, 22(1), 946. [946]. https://doi.org/10.1186/s12885-022-09891-9
Sharples, L., Sastry, P., Freeman, C., Gray, J., McCarthy, A., Chiu, Y-D., Bicknell, C., McMeekin, P., Vallabhaneni, S. R., Cook, A., Vale, L., & Large, S. (2022). Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study. Health Technology Assessment, 26(6), 1-166. https://doi.org/10.3310/ABUT7744
Lim, S. H., Stuart, B., Joseph-Pietras, D., Johnson, M., Campbell, N., Kelly, A., Jeffrey, D., Turaj, A. H., Rolfvondenbaumen, K., Galloway, C., Wynn, T., Coleman, A. R., Ward, B., Long, K., Coleman, H., Mundy, C., Bates, A. T., Ayres, D., Lown, R., ... Goldblatt, D. (2022). Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study. Nature cancer, 3(5), 552-564. https://doi.org/10.1038/s43018-022-00364-3
ORANGE trials collaborative (2022). Laparoscopic versus open resections in the posterosuperior liver segments within an enhanced recovery programme (ORANGE Segments): study protocol for a multicentre randomised controlled trial. Trials, 23(1), 206. [206]. https://doi.org/10.1186/s13063-022-06112-3
Soilemezi, D., Roberts, H. C., Navarta‐sánchez, M. V., Kunkel, D., Ewings, S., Reidy, C., & Portillo, M. C. (2022). Managing Parkinson’s during the COVID‐19 pandemic: perspectives from people living with Parkinson’s and health professionals. Journal of Clinical Nursing. https://doi.org/10.1111/jocn.16367
AGILE CST-2 Study Group, Khoo, S. H., FitzGerald, R., & Saunders, G. (2022). Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial. The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(22)00644-2
Hristova, V. A., Watson, A., Chaerkady, R., Glover, M. S., Ackland, J., Angermann, B., Belfield, G., Belvisi, M., Burke, H., Cellura, D., Clark, H. W., Etal, D., Freeman, A., Heinson, A., Hess, S., Hühn, M., Hall, E., Mackay, A., Madsen, J., ... MICA II Studygroup (Accepted/In press). Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD. ERJ Open Research.
Zhang, H., Lam, C. S. Y., Tang, W. C., Leung, M., Qi, H., Lee, P. H., & To, C. H. (2022). Myopia control effect Is influenced by baseline relative peripheral refraction in children wearing Defocus Incorporated Multiple Segments (DIMS) Spectacle Lenses. Journal of Clinical Medicine, 11(9), [2294]. https://doi.org/10.3390/jcm11092294
Lam, C. S. Y., Tang, W. C., Lee, P. H., Zhang, H. Y., Qi, H., Hasegawa, K., & To, C. H. (2022). Myopia control effect of defocus incorporated multiple segments (DIMS) spectacle lens in Chinese children: results of a 3-year follow-up study. British Journal of Ophthalmology, 106(8), 1110-1114. https://doi.org/10.1136/bjophthalmol-2020-317664
Crabb, S. J., Griffiths, G., Dunkley, D., Downs, N., Ellis, M., Radford, M., Light, M., Northey, J., Whitehead, A., Wilding, S., Birtle, A. J., Khoo, V., & Jones, R. J. (2022). Overall survival update for patients with metastatic castration-resistant prostate cancer treated with Capivasertib and docetaxel in the Phase 2 ProCAID clinical trial. European Urology, 82(5), 512-515. https://doi.org/10.1016/j.eururo.2022.05.019
Essery, R., Pollet, S., Bradbury, K., Western, M. J. J., Grey, E., Denison-Day, J., Smith, K. A., Hayter, V., Kelly, J., Somerville, J., Stuart, B., Becque, T., Zhang, J., Slodkowska-Barabasz, J., Mowbray, F., Ferrey, A., Yao, G., Zhu, S., Kendrick, T., ... Yardley, L. (2022). Parallel randomized controlled feasibility trials of the "Active Brains" digital intervention to protect cognitive health in adults aged 60-85. Frontiers in Public Health, 10, [962873]. https://doi.org/10.3389/fpubh.2022.962873
O'Connor, S. R., Lotery, A., Treanor, C., Ward, E., Wickens, R., O'Connell, A., Culliford, L. A., Rogers, C. A., Gidman, E. A., Peto, T., Knox, P. C., Burton, B. J. L., Lotery, A. J., Sivaprasad, S., Reeves, B. C., Hogg, R. E., & Donnellan, M. A. (2022). Patient acceptability of home monitoring for neovascular age-related macular degeneration reactivation: A qualitative study. International Journal of Environmental Research and Public Health, 19(20), [13714]. https://doi.org/10.3390/ijerph192013714
et al., Välimäki, M., Lam, Y. T. J., Hipp, K., & Lee, P. (2022). Physical restraint events in psychiatric hospitals in Hong Kong: a cohort register study. International Journal of Environmental Research and Public Health, 19(10), [6032]. https://doi.org/10.3390/ijerph19106032
Easton, S., Ainsworth, B., Thomas, M., Latter, S., Knibb, R., Cook, A., Wilding, S., Bahrami-Hessari, M., Kennington, E. J., Gibson, D., Wilkins, H., Yardley, L., & Roberts, G. (Accepted/In press). Planning a digital intervention for adolescents with asthma (BREATHE4T): a, theory-, evidence- and Person-Based Approach to identify key behavioural issues. Pediatric Pulmonology.
Hack, J., & Crabb, S. (2022). Platinum-based chemotherapy ‘Rechallenge’ in advanced non-ovarian solid malignancies. Clinical Oncology, 34(8), e329-e344. https://doi.org/10.1016/j.clon.2022.02.015
Ewings, S., Saunders, G., Jaki, T., & Mozgunov, P. (2022). Practical recommendations for implementing a Bayesian adaptive phase I design during a pandemic. BMC Medical Research Methodology, 22(1), [25]. https://doi.org/10.1186/s12874-022-01512-0
Tang, A. C. Y., Lee, P. H., Lam, S. C., Siu, S. C. N., Ye, C. J., & Lee, R. L-T. (2022). Prediction of problem gambling by demographics, gaming behavior and psychological correlates among gacha gamers: A cross-sectional online survey in Chinese young adults. Frontiers in Psychiatry, 13, [940281]. https://doi.org/10.3389/fpsyt.2022.940281
Hodgson, S., Morgan-Harrisskit, J., Hounkpatin, H., Stuart, B., & Dambha-Miller, H. (2022). Primary care service utilisation and outcomes in type 2 diabetes: a longitudinal cohort analysis. BMJ Open, 12(1), [e054654]. https://doi.org/10.1136/bmjopen-2021-054654
Zhu, S., Zhuang, Y., & Lee, P. (2022). Psychometric properties of the Mindsets of Depression, Anxiety, and Stress Scale (MDASS) in Chinese young adults and adolescents. Early Intervention in Psychiatry, 16(4), 380-392. https://doi.org/10.1111/eip.13177
Kwan, R. Y. C., Liu, J. Y. W., Yin, Y. H., Lee, P. H., Ng, S. Y., Cheung, D. S. K., Kor, P. P. K., Lam, S. C., Lo, S. K. L., Yang, L., Chan, S. K., & Chiang, V. C. L. (2022). Sarcopenia and its association with objectively measured life-space mobility and moderate-to-vigorous physical activity in the oldest-old amid the COVID-19 pandemic when a physical distancing policy is in force. BMC Geriatrics, 22(1), [250]. https://doi.org/10.1186/s12877-022-02861-7
Lown, M., Miles, E., Fisk, H. L., Smith, K. A., Muller, I., Maund, E., Rogers, K. L., Becque, T., Hayward, G., Moore, M., Little, P., Glogowska, M., Hay, A. D., Stuart, B., Mantzourani, E., Butler, C., Bostock, J., Davies, F., Dickerson, I., ... Francis, NA. (2022). Self-sampling to identify pathogens and inflammatory markers in patients with acute sore throat: feasibility study. Frontiers in Immunology, 13, [1016181]. https://doi.org/10.3389/fimmu.2022.1016181
Tse, A. C. Y., Lee, P. H., Lau, E. Y. Y., Cheng, J. C. H., Ho, A. W. Y., & Lai, E. W. H. (2022). Study protocol for a randomized controlled trial comparing the effectiveness of physical exercise and melatonin supplement on treating sleep disturbance in children with autism spectrum disorders. PLoS ONE, 17(7), [e0270428]. https://doi.org/10.1371/journal.pone.0270428
GBD 2019 mental disorders collaborator, & Lee, P. (2022). The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019. The Lancet Regional Health - Europe, 16, 100341. [100341]. https://doi.org/10.1016/j.lanepe.2022.100341
O'Connor, S. R., Treanor, C., Ward, E., Wickens, R., O'Connel, A., Culliford, L. A., Rogers, C. A., Gidman, E. A., Peto, T., Knox, P. C., Burton, B. J. L., Lotery, A., Sivaprasad, S., Reeves, B. C., Hogg, R. E., & Donnelly, M. (2022). The COVID-19 pandemic and ophthalmic care: A qualitative study of patients with neovascular Age-Related Macular Degeneration (nAMD). International Journal of Environmental Research and Public Health. http://10.3390/ijerph19159488
Hu, XY., Oliver, T., Willcox, M., Simpson, C., Thorne, K., Trill, J., Francis, NA., Stuart, B., Thomas, M., Little, P., Liu, JP., Griffiths, G., & Moore, M. (2022). Treating Acute EXacerbations of COPD with Chinese HerbAL MedIcine to aid AntiBiotic Use Reduction (EXCALIBUR): study protocol of a randomised double-blind, placebo-controlled feasibility trial. Pilot and Feasibility Studies, 8(1), [262]. https://doi.org/10.1186/s40814-022-01224-8
Hu, X-Y., Oliver, T., Willcox, M., Simpson, C., Thorne, K., Trill, J., Francis, N., Stuart, B., Thomas, M., Little, P., Liu, J-P., Griffiths, G., & Moore, M. (2022). Treating Acute EXacerbations of COPD with Chinese HerbAL MedIcine to aid AntiBiotic Use Reduction (EXCALIBUR): study protocol of a randomised double-blind, placebo-controlled feasibility trial. Pilot and Feasibility Studies, 8(1). https://doi.org/10.1186/s40814-022-01224-8
Bancroft, E. K., Page, E. C., Brook, M. N., Thomas, S., Taylor, N., Pope, J., & The IMPACT Study Collaborators (2021). A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study. The Lancet Oncology, 22(11), 1618-1631. https://doi.org/10.1016/S1470-2045(21)00522-2
Patel, S., Ormesher, D., Smith, S., Wong, K., Bevis, P., Bicknell, C., Boyle, J., Brennan, J., Campbell, B., Cook, A., Crosher, A., Duarte, R., Flett, M., Gamble, C., Jackson, R., Juszczak, M., Loftus, I., Norton, I., Patel, J., ... Vallabhaneni, S. R. (2021). A risk-adjusted and anatomically stratified cohort comparison study of open surgery, endovascular techniques and medical management for juxtarenal aortic aneurysms—the UK COMPlex AneurySm Study (UK-COMPASS): a study protocol. BMJ Open. https://doi.org/10.1136/bmjopen-2021-054493
AGILE investigators, Griffiths, G. O., FitzGerald, R., Jaki, T., Corkhill, A., Reynolds, H., Ewings, S., & Condie, S. (2021). AGILE: a seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment: an update to the structured summary of a study protocol for a randomised platform trial letter. Trials, 22, [487 (2021)]. https://doi.org/10.1186/s13063-021-05458-4
AGILE platform (2021). An open label, adaptive, phase 1 trial of high-dose oral nitazoxanide in healthy volunteers: an antiviral candidate for SARS-CoV-2. Clinical Pharmacology and Therapeutics. https://doi.org/10.1002/cpt.2463
Sharples, L., Sastry, P., Freeman, C., Bicknell, C., Chiu, Y-D., Vallabhaneni, S. R., Cook, A., Gray, J., McCarthy, A., McMeekin, P., Vale, L., & Large, S. (2021). Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study. European Heart Journal, 1-14. https://doi.org/10.1093/eurheartj/ehab784
Dambha-Miller, H., Hounkpatin, H., Stuart, B., & Farmer, A. (2021). Association between weight change and remission of type 2 diabetes: a retrospective cohort study in primary care. Practical Diabetes, 38(5), 8-14a. https://doi.org/10.1002/pdi.2355
Hounkpatin, H., Stuart, B., Farmer, A., & Dambha-Miller, H. (2021). Association of type 2 diabetes remission and risk of cardiovascular disease in pre-defined subgroups. Endocrinology, Diabetes & Metabolism, 4(3), [e00280]. https://doi.org/10.1002/edm2.280
Santoni, M., Massari, F., Bracarda, S., Procopio, G., Milella, M., De Giorgi, U., Basso, U., Aurilio, G., Incorvaia, L., Martignetti, A., Rizzo, M., Cartenì, G., Grande, E., Matrana, M. R., Crabb, S. J., Vau, N., Sorgentoni, G., Cimadamore, A., Montironi, R., & Battelli, N. (2021). Body mass index in patients treated with cabozantinib for advanced renal cell carcinoma: A new prognostic factor? Diagnostics, 11(1), [138]. https://doi.org/10.3390/diagnostics11010138
Hydes, T., Moore, M., Stuart, B., Kim, M., Su, F., Newell, C., Cable, D., Hales, A., & Sheron, N. (2021). Can routine blood tests be modelled to detect advanced liver disease in the community: model derivation and validation using UK primary and secondary care data. BMJ Open, 11(2), e044952. [e044952]. https://doi.org/10.1136/bmjopen-2020-044952
Lim, S. H., Sow, H. S., Wignall, C., Mercer, K., Caddy, J., Boxall, C., Thorne, K., Northey, J., Stanton, L., Konn, Z., Fines, K., Medd, P. G., Coleman, A., Nunn, L., Lown, R., Mckay, P., Osborne, W., Linton, K., Collins, G. P., ... Griffiths, G. (2021). Clinical and biological effects of combined CD27 and CD20 antibody therapy in relapsed/refractory B-cell lymphoma: the Riva trial. Blood, 138(Supplement 1), 715-715. https://doi.org/10.1182/blood-2021-148332
Zhang, M., Luo, J-L., Sun, Q., Harber, J., Dawson, A. G., Nakas, A., Busacca, S., Sharkey, A. J., Waller, D., Sheaff, M. T., Richards, C., Wells-Jordan, P., Gaba, A., Poile, C., Baitei, E. Y., Bzura, A., Dzialo, J., Jama, M., Le Quesne, J., ... Fennell, D. A. (2021). Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. Nature Communications, 12(1), [1751]. https://doi.org/10.1038/s41467-021-21798-w
Gilbert, F. J., Harris, S., Miles, K. A., Weir-McCall, J., Qureshi, N. R., Rintoul, R. C., Dizdarevic, S., Pike, L., Sinclair, D., Shah, A., Eaton, R., Jones, J., Clegg, A. J., Vitiello, B., Hill, J., Cook, A., Tzelis, D., Vale, L., Brindle, L., ... George, S. (2021). Comparative accuracy and cost-effectiveness of dynamic contrast-enhanced CT and positron emission tomography in the characterisation of solitary pulmonary nodules. Thorax, [216948]. https://doi.org/10.1136/thoraxjnl-2021-216948
Hall, N., Sherratt, F. C., Eaton, S., Reading, I., Walker, E., Chorozoglou, M., Beasant, L., Wood, W., Stanton, M., Corbett, H., Rex, D., Hutchings, N., Dixon, E., Grist, S., Van't Hoff, W., Crawley, E. M., Blazeby, J. M., & Young, B. (2021). Conservative treatment for uncomplicated appendicitis in children: the CONTRACT feasibility study, including feasibility RCT. Health Technology Assessment, 25(10). https://doi.org/10.3310/hta25100
Hall, N., Eaton, S., Sherratt, F. C., Reading, I., Walker, E., Chorozoglou, M., Beasant, L., Wood, W., Stanton, M., Corbett, H., Rex, D., Hutchings, N. J., Dixon, E., Grist, S., Crawley, E. M., Young, B., & Blazeby, J. M. (2021). CONservative TReatment of Appendicitis in Children – a randomised controlled feasibility Trial (CONTRACT). Archives of Disease in Childhood, 106(8), 764-773. https://doi.org/10.1136/archdischild-2020-320746
Stuart, B., Hounkpatin, H., Becque, T., Yao, G., Zhu, S., Alonso-Coello, P., Altiner, A., Arroll, B., Böhning, D., Bostock, J., Bucher, H. C., Chao, J., De La Poza, M., Francis, N., Gillespie, D., Hay, A. D., Kenealy, T., Löffler, C., McCormick, D. P., ... Little, P. (2021). Delayed antibiotic prescribing for respiratory tract infections: Individual patient data meta-analysis. The BMJ, 373, [n808]. https://doi.org/10.1136/bmj.n808
OCTOPuS Study Group, Holt, R., Barnard-Kelly, K., Dritsakis, G., Thorne, K., Cohen, L., Dixon, E., Patel, M., & Cook, A. (2021). Developing an intervention to optimise the outcome of cardiac surgery in people with diabetes: the OCTOPuS pilot study. Pilot and Feasibility Studies, 7(1), [157]. https://doi.org/10.1186/s40814-021-00887-z
Hu, Y. J., Zhou, X., Wang, S., Willcox, M., Garner, C., Brown, D., Becque, T., Stuart, B., Han, Z., Chang, Q., Moore, M., & Little, P. (2021). Diarrhoea Management using Over-the-counter Nutraceuticals in Daily practice (DIAMOND): a feasibility RCT on alternative therapy to reduce antibiotic use. Pilot and Feasibility Studies, 7(1), 126. [126]. https://doi.org/10.1186/s40814-021-00850-y
Bishop, F., Al-Abbadey, M., Roberts, L., MacPherson, H., Stuart, B., Carnes, D., Fawkes, C., Yardley, L., & Bradbury, K. (2021). Direct and mediated effects of treatment context on low back pain outcome: a prospective cohort study. BMJ Open, 11(5), [e044831]. https://doi.org/10.1136/bmjopen-2020-044831
et al., Howells, L., Gran, S., Stuart, B., Santer, M., Bradshaw, L., Huang, C., Francis, N. A., & Thomas, K. S. (2021). Do patient characteristics matter when calculating sample size for eczema clinical trials? Skin Health and Disease Open Access, 1(3), e42. https://doi.org/10.1002/ski2.42
Long, A. M., Jones, I. H., Knight, M., McNally, J., & BAPS-CASS (2021). Early management of meconium ileus in infants with cystic fibrosis: A prospective population cohort study. Journal of Pediatric Surgery, 56(8), 1287-1292. https://doi.org/10.1016/j.jpedsurg.2021.02.047
Wong, A. K. C., Wong, F. K. Y., Chow, K. K. S., Wong, S. M., & Lee, P. H. (2021). Effect of a telecare case management program for older adults who are homebound during the COVID-19 pandemic: a pilot randomized clinical trial. JAMA Network Open, 4(9), [e2123453]. https://doi.org/10.1001/jamanetworkopen.2021.23453
So, B. C. L., Kwok, S. C., & Lee, P. H. (2021). Effect of aquatic exercise on sleep efficiency of adults with chronic musculoskeletal pain. Journal of Physical Activity and Health, 18(9), 1037-1045. https://doi.org/10.1123/jpah.2020-0476
Tse, M. M. Y., Ng, S. S. M., Lee, P. H., Bai, X., Lo, R., Tang, S. K., Chan, K. L., & Li, Y. (2021). Effectiveness of a peer-led pain management program in relieving chronic pain and enhancing pain self-efficacy among older adults: a clustered randomized controlled trial. Frontiers in Medicine, 8, [709141]. https://doi.org/10.3389/fmed.2021.709141
et al., Siu, P. M., Yu, A. P., Tam, B. T., & Lee, P. H. (2021). Effects of Tai Chi or exercise on sleep in older adults with insomnia: A Randomized Clinical Trial. JAMA Network Open, 4(2), e2037199. https://doi.org/10.1001/jamanetworkopen.2020.37199
Liu, J. Y. W., Kwan, R. Y. C., Yin, Y. H., Lee, P. H., Siu, J. Y. M., & Bai, X. (2021). Enhancing the physical activity levels of frail older adults with a wearable activity tracker‐based exercise intervention: A pilot cluster randomized controlled trial. International Journal of Environmental Research and Public Health, 18(19), [10344]. https://doi.org/10.3390/ijerph181910344
et al., Tyrovolas, S., Giné-Vázquez, I., Fernández, D., Lin, Y., & Lee, P. (2021). Estimating the COVID-19 spread through real-time population mobility patterns: Surveillance in low-and middle-income countries. Journal of Medical Internet Research, 23(6), [e22999]. https://doi.org/10.2196/22999
Kwan, R. Y. C., Lee, P. H., Cheung, D. S. K., & Lam, S. C. (2021). Face mask wearing behaviors, depressive symptoms, and health beliefs among older people during the COVID-19 pandemic. Frontiers in Medicine, 8. https://doi.org/10.3389/fmed.2021.590936
FORECAST Investigators (2021). Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial. European Heart Journal, 42(37), 3844-3852. https://doi.org/10.1093/eurheartj/ehab444
The International Research Collaboration on COVID-19, Cheung, T., Lam, S. C., & Lee, P. H. (2021). Global imperative of suicidal ideation in 10 countries amid the COVID-19 pandemic. Frontiers in Psychiatry, 11, [588781]. https://doi.org/10.3389/fpsyt.2020.588781
McManus, R., Little, P., Stuart, B., Morton, K. S., Raftery, J., Kelly, J. M., Bradbury, K., Zhang, J., Zhu, S., Murray, E., May, C. R., Mair, F., Michie, S., Smith, P. W. F., Band, R., Ogburn, E., Allen, J., Rice, C., Nuttall, J., ... Yardley, L. (2021). Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial. British Medical Journal, 372, [m4858]. https://doi.org/10.1136/bmj.m4858
Ainsworth, B., Miller, S., Denison-Day, J., Stuart, B., Groot, J., Rice, C., Bostock, J., Hu, X., Morton, K., Towler, L. B., Moore, M., Willcox, M., Chadborn, T., Gold, N., Amlôt, R., Little, P., & Yardley, L. (2021). Infection control behavior at home during the COVID-19 pandemic: Observational study of a web-based behavioral intervention (Germ Defence). Journal of Medical Internet Research, 23(2), [e22197]. https://doi.org/10.2196/22197
Zhu, S., Lee, P. H., & Wong, P. W. C. (2021). Investigating prolonged social withdrawal behaviour as a risk factor for self-harm and suicidal behaviours. BJPsych Open, 7(3). https://doi.org/10.1192/bjo.2021.47
Tse, A. C. Y., Liu, V. H. L., & Lee, P. H. (2021). Investigating the matching relationship between physical exercise and stereotypic behavior in children with autism. Medicine and Science in Sports and Exercise, 53(4), 770-775. https://doi.org/10.1249/MSS.0000000000002525
Zhu, S., Zhuang, Y., Lee, P., Chi-Mei Li, J., & Wong, P. W. C. (2021). Leisure and problem gaming behaviors among children and adolescents during school closures caused by covid-19 in hong kong: Quantitative cross-sectional survey study. JMIR Serious Games, 9(2), [e26808]. https://doi.org/10.2196/26808
International Extranodal Lymphoma Study Group (IELSG) (2021). MATRix-RICE therapy and autologous haematopoietic stem-cell transplantation in diffuse large B-cell lymphoma with secondary CNS involvement (MARIETTA): an international, single-arm, phase 2 trial. The Lancet Haematology, 8(2), e110-e121. https://doi.org/10.1016/S2352-3026(20)30366-5
Stuart, B., Howells, L., Pattinson, R., Chalmers, J. R., Grindlay, D., Rogers, N., Grinich, E., Pawlitschek, T., Simpson, E. L., & Thomas, K. (Accepted/In press). Measurement properties of patient reported outcome measures for eczema control: a systematic review. Journal of the European Academy of Dermatology and Venereology.
CONFIRM trial investigators (2021). Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial. Lancet Oncology, 22(11), 1530-1540. https://doi.org/10.1016/S1470-2045(21)00471-X, https://doi.org/10.1016/S1470-2045(21)00471-X
Khoo, S. H., Fitzgerald, R., Fletcher, T., Ewings, S., Jaki, T., Lyon, R., Downs, N., Walker, L., Tansley-Hancock, O., Greenhalf, W., Woods, C., Reynolds, H., Marwood, E., Mozgunov, P., Adams, E., Bullock, K., Holman, W., Bula, M. D., Gibney, J. L., ... Griffiths, G. (2021). Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study. Journal of Antimicrobial Chemotherapy, 76(12), 3286-3295. https://doi.org/10.1093/jac/dkab318
Mukherjee, S., Hurt, C., Radhakrishna, G., Gwynne, S., Bateman, A., Gollins, S., Hawkins, M. A., Canham, J., Grabsch, H. I., Falk, S., Sharma, R. A., Ray, R., Roy, R., Cox, C., Maynard, N., Nixon, L., Sebag-Montefiore, D. J., Maughan, T., Griffiths, G. O., & Crosby, T. D. L. (2021). Oxaliplatin/capecitabine or carboplatin/paclitaxel-based preoperative chemoradiation for resectable oesophageal adenocarcinoma (NeoSCOPE): long-term results of a randomised controlled trial. European Journal of Cancer, 153, 153-161. https://doi.org/10.1016/j.ejca.2021.05.020
Adamson, D., Byrne, A., Porter, C., Blazeby, J., Griffiths, G., Nelson, A., Sewell, B., Jones, M., Svobodova, M., Fitzsimmons, D., Nixon, L., Fitzgibbon, J., Thomas, S., Millin, A., Crosby, T., Staffurth, J., & Hurt, C. (2021). Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial. The Lancet Gastroenterology & Hepatology, 6(4), 292-303. https://doi.org/10.1016/S2468-1253(21)00004-2
Adamson, D., Blazeby, J., Porter, C., Hurt, C., Griffiths, G., Nelson, A., Sewell, B., Jones, M., Svobodova, M., Fitzsimmons, D., Nixon, L., Fitzgibbon, J., Thomas, S., Millin, A., Crosby, T., Staffurth, J., & Byrne, A. (2021). Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT. Health technology assessment (Winchester, England), 25(31). https://doi.org/10.3310/hta25310
Willcox, M., Simpson, C., Wilding, S., Stuart, B., Soilemezi, D., Whitehead, A., Morgan, A., Wrixon, E., Zhu, S., Yao, G., Webley, F., Yan, R., Bostock, J., Bell, M., Griffiths, G., Leydon, G., Little, P., Butler, C., Hay, A. D., & Moore, M. (2021). Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial. BMC Complementary Medicine and Therapies, 21(1), [48]. https://doi.org/10.1186/s12906-021-03206-4
Crabb, S. J., Danson, S., Catto, J. W. F., Hussain, S., Chan, D., Dunkley, D., Downs, N., Marwood, E., Day, L., Saunders, G. N., Light, M., Whitehead, A., Ellis, D., Sarwar, N., Enting, D., Birtle, A. J., Johnson, B., Huddart, R., & Griffiths, G. (2021). Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE). Clinical Cancer Research, 27(7), 1882-1892. https://doi.org/10.1158/1078-0432.CCR-20-3946
Beard, D., Campbell, M., Blazeby, J. M., Carr, A., Weijer, C., Cuthbertson, B. H., Buchbinder, R., Pinkney, T., Bishop, F., Pugh, J., Cousins, S., Harris, I., Lohmander, L. S., Blencowe, N. S., Gilles, K., Probst, P., Brennan, C., Cook, A., Farrar-Hockley, D., ... Cook, J. (2021). Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop. Health Technology Assessment, 25(53). https://doi.org/10.3310/hta25530
Essery, R., Pollet, S., Smith, K., Mowbray, F., Slodkowska-Barabasz, J., Denison-Day, J., Hayter, V., Bradbury, K., Grey, E., Western, M., Milton, A. MC., Hunter, C., Ferrey, A., Muller, A. M., Stuart, B., Mutrie, N., Griffin, S. J., Kendrick, T., Brooker, H., ... Yardley, L. (2021). Planning and optimising a digital intervention to protect older adults’ cognitive health. Pilot and Feasibility Studies, 7(1), [158]. https://doi.org/10.1186/s40814-021-00884-2
Francis, N. A., Stuart, B., Knight, M., Vancheeswaran, R., Oliver, C., Willcox, M., Barlow, A., & Moore, M. (2021). Predictors of clinical deterioration in patients with suspected COVID-19 managed in a virtual hospital' setting: A cohort study. BMJ Open, 11(3), [e045356]. https://doi.org/10.1136/bmjopen-2020-045356
Lown, M., McKeown, S., Stuart, B., Francis, N., Santer, M., Lewith, G., Su, F., Moore, M., & Little, P. (2021). Prescribing of long-term antibiotics to adolescents in primary care: a retrospective cohort study. The British journal of general practice : the journal of the Royal College of General Practitioners, 71(713), e887-e894. https://doi.org/10.3399/BJGP.2021.0332
Calman, L., Turner, J., Fenlon, D. R., Permyakova, N. V., Wheelwright, S., Patel, M. I., Din, A., Winter, J., Richardson, A., Smith, P. W. F., & Foster, C. (2021). Prevalence and determinants of depression up to 5 years after colorectal cancer surgery: results from the ColoREctal Wellbeing (CREW) study. Colorectal Disease. https://doi.org/10.1111/codi.15949
Dambha-Miller, H., Hounkpatin, H., Harrisskitt-Morgan, J., Stuart, B., Fraser, S., & Roderick, P. (2021). Primary care consultations for respiratory tract symptoms during the COVID-19 pandemic: a cohort study including 70 000 people in South West England. Family Practice. https://doi.org/10.1093/fampra/cmab127
Lee, P. H., Marek, J., & Nálevka, P. (2021). Sleep pattern in the US and 16 European countries during the COVID-19 outbreak using crowdsourced smartphone data. European Journal of Public Health, 31(1), 23-30. https://doi.org/10.1093/eurpub/ckaa208
Renz, S., Chinnery, F., Stuart, B., Day, L., Muller, I., Soulsby, I., Nuttall, J., Thomas, K., Thomas, K. S., Sach, T., Stanton, L., Ridd, M. J., Francis, N., Little, P., Eminton, Z., Griffiths, G., Layton, A. M., & Santer, M. (2021). Spironolactone for adult female acne (SAFA): protocol for a double-blind, placebo-controlled, phase III randomised study of spironolactone as systemic therapy for acne in adult women. BMJ Open, 11(8), e053876. [e053876]. https://doi.org/10.1136/bmjopen-2021-053876
Muller, I., Stuart, B., Sach, T., Hooper, J., Wilczynska, S., Steele, M., Greenwell, K., Sivyer, K., Yardley, L., Williams, H. C., Chalmers, J. R., Leighton, P., Howells, L. M., Ridd, M. J., Lawton, S., Griffiths, G., Nuttall, J., Langan, S. M., Roberts, A., ... Santer, M. (2021). Supporting self-care for eczema: protocol for two randomised controlled trials of ECO (Eczema Care Online) interventions for young people and parents/carers. BMJ Open, 11(2), 1-8. [045583]. https://doi.org/10.1136/bmjopen-2020-045583, https://doi.org/10.1136/ bmjopen-2020-045583
Ip, A., Muller, I., Geraghty, A., Rumsby, K., Stuart, B., Little, P., & Santer, M. (2021). Supporting self-management among young people with acne vulgaris through a web-based behavioral intervention: development and feasibility randomized controlled trial. JMIR Dermatology, 4(2), [2]. https://doi.org/10.2196/25918
McCarthy, A., Gray, J., Sastry, P., Sharples, L., Vale, L., Cook, A., McMeekin, P., Freeman, C., Catarino, P., & Large, S. (2021). Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms. BMJ Open, 11(3), [e043323]. https://doi.org/10.1136/bmjopen-2020-043323
Lee, P. H., Tse, A. C. Y., Wu, C. S. T., Mak, Y. W., & Lee, U. (2021). Temporal association between objectively measured smartphone usage, sleep quality and physical activity among Chinese adolescents and young adults. Journal of Sleep Research, 30(4), [e13213]. https://doi.org/10.1111/jsr.13213
Zhu, S., Zhuang, Y., Lee, P., & Wong, P. W. C. (2021). The changes of suicidal ideation status among young people in Hong Kong during COVID-19: a longitudinal survey. Journal of Affective Disorders, 294(11), 151-158. https://doi.org/10.1016/j.jad.2021.07.042
Bruyndonckx, R., Stuart, B., Little, P., Hens, N., Ieven, M., Butler, C. C., Verheij, T. J. M., Goossens, H., & Coenen, S. (2021). The effect of amoxicillin in adult patients presenting to primary care with acute cough predicted to have pneumonia or a combined viral-bacterial infection. Antibiotics, 10(7), [817]. https://doi.org/10.3390/antibiotics10070817
Holt, R. I. G., Dritsakis, G., Barnard-Kelly, K., Thorne, K., Whitehead, A., Cohen, L., Dixon, E., Patel, M., Newland-Jones, P., Green, M., Partridge, H., Luthra, S., Ohri, S., Salhiyyah, K., Lord, J., Niven, J., & Cook, A. (2021). The Optimising Cardiac Surgery ouTcOmes in People with diabeteS (OCTOPuS) randomised controlled trial to evaluate an outpatient pre-cardiac surgery diabetes management intervention: a study protocol. BMJ Open, 11(6), e050919. [050919]. https://doi.org/10.1136/bmjopen-2021-050919
Whicher, C. A., Price, H. C., Phiri, P., Rathod, S., Barnard-Kelly, K., Kandala, N. I. I., Thorne, K., Asher, C., Peveler, R., McCarthy, J., & Holt, R. (2021). The use of liraglutide 3.0 mg daily in the management of overweight and obesity in people with schizophrenia, schizoaffective disorder and first episode psychosis: Results of a pilot randomized, double-blind, placebo-controlled trial. Diabetes, Obesity and Metabolism, 23(6), 1262-1271. https://doi.org/10.1111/dom.14334
The RECOVERY Collaborative Group (2021). Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet (London, England), 397(10285), 1637-1645. https://doi.org/10.1016/S0140-6736(21)00676-0, https://doi.org/10.1016/S0140-6736(21)00676-0
Hounkpatin, H., Woods, C., Lown, M., Stuart, B., & Leydon, G. (Accepted/In press). Understanding general practitioners’ views and experiences of using clinical prediction rules in the management of respiratory infections: a qualitative study. BJGP Open.
Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C., & Day, S. (2021). Utilising benefit-risk assessments within clinical trials—a protocol for the BRAINS project. Trials, 22(68), [68]. https://doi.org/10.1186/s13063-021-05022-0
Lee, P. H., Tse, A. C. Y., Wu, C. S. T., Mak, Y. W., & Lee, U. (2021). Validation of self-reported smartphone usage against objectively-measured smartphone usage in hong kong chinese adolescents and young adults. Psychiatry Investigation, 18(2), 95-100. https://doi.org/10.30773/pi.2020.0197
Lee, P. H. (Accepted/In press). Validation of the National Health and nutritional survey (NHANES) single-item self-reported sleep duration against wrist-worn accelerometer. Sleep and Breathing, 26(4), 2069–2075. https://doi.org/10.1007/s11325-021-02542-6
Hulbert, S., Chivers-seymour, K., Summers, R., Lamb, S., Goodwin, V., Rochester, L., Nieuwboer, A., Rowsell, A., Ewing, S., & Ashburn, A. (2020). ‘PDSAFE’ - a multi-dimensional model of falls-rehabilitation for people with Parkinson’s. A mixed methods analysis of therapists’ delivery and experience. Physiotherapy. https://doi.org/10.1016/j.physio.2020.08.006
Dall'ora, C., Griffiths, P., Emmanuel, T., Rafferty, A. M., & Ewings, S. (2020). 12‐hr shifts in nursing: Do they remove unproductive time and information loss or do they reduce education and discussion opportunities for nurses? A cross‐sectional study in 12 European countries. Journal of Clinical Nursing, 29(1-2). https://doi.org/10.1111/jocn.14977
Lee, R. L. T., Leung, C., Chen, H., Lee, P. H., & Kwok, S. W. H. (2020). A cluster randomized controlled trial of a simplified 5-step handwashing technique versus a conventional 7-step handwashing technique among Chinese students with intellectual disabilities. Journal of Applied Research in Intellectual Disabilities, 33(5), 1090-1099. https://doi.org/10.1111/jar.12731
Irvine, A., Waise, S., Green, E., & Stuart, B. (Accepted/In press). A non-linear optimisation method to extract summary statistics from Kaplan-Meier survival plots using the published P value. BMC Medical Research Methodology.
Davies, A., Mansbridge, C., Simmonds, P., Murray, N., Stanton, L., Chinnery, F., Archer, C., Barrett-Lee, P., Hickish, T., & Crabb, S. (2020). A phase 2 open-label study of carboplatin in combination with gemcitabine as a dose-dense schedule in patients with locally advanced or metastatic breast cancer that are resistant to anthracyclines and taxanes. F1000 Research. https://f1000research.com/articles/9-4
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., Evans, L., Lester, J., Jagdev, S., Casbard, A., Huang, C., Madden, T-A., & Griffiths, G. (2020). A randomised phase II trial of carboplatin and gemcitabine +/- vandetanib in first line treatment of advanced urothelial cell cancer patients not suitable to receive cisplatin. BJU International, 126(2), 292-299. https://doi.org/10.1111/bju.15096
Kwan, R. Y. C., Liu, J. Y. W., Lee, D., Tse, C. Y. A., & Lee, P. H. (2020). A validation study of the use of smartphones and wrist-worn ActiGraphs to measure physical activity at different levels of intensity and step rates in older people. Gait and Posture, 82(10), 306-312. https://doi.org/10.1016/j.gaitpost.2020.09.022
et al., Davies, A., Caddy, J., Mercer, K., Stanton, L., Cummin, T. E. C., Coleman, A., Griffiths, G., & Johnson, P. (2020). Acalabrutinib in Combination with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone (R-CHOP) as first line therapy for patients with diffuse Large B-Cell Lymphoma (DLBCL): The Accept Phase Ib/II single arm study. Blood, 136(Supplement 1), 38-39. https://doi.org/10.1182/blood-2020-134546
Griffiths, G., Fitzgerald, R., Jaki, T., Corkhill, A., Marwood, E., Reynolds, H., Stanton, L., Ewings, S., Condie, S., Wrixon, E., Norton, A., Radford, M., Yeats, S., Robertson, J., Darby-Dowman, R., Walker, L., Khoo, S., & UK NIHR community (2020). AGILE-ACCORD: a randomized, multicentre, seamless, adaptive phase I/II platform study to determine the optimal dose, safety and efficacy of multiple candidate agents for the treatment of COVID-19: a structured summary of a study protocol for a randomised platform trial. Trials, 21(1), 1-3. [544]. https://doi.org/10.1186/s13063-020-04473-1
Tse, M., Li, Y., Tang, S. K., Ng, S. S. M., Bai, X., Lee, P. H., Lo, R., & Yeung, S. S. Y. (2020). An exploration of the effectiveness of a peer-led pain management program (PAP) for nursing home residents with chronic pain and an evaluation of their experiences: a pilot randomized controlled trial. International Journal of Environmental Research and Public Health, 17(11), [4090]. https://doi.org/10.3390/ijerph17114090
Tse, M. M. Y., Ng, S. S. M., Bai, X., Lee, P. H., Lo, R., Yeung, S. S. Y., Li, Y., & Tang, S. K. (2020). An exploration of the use of visually appealing contexts in a pain management program. European Geriatric Medicine, 11(5), 821-827. https://doi.org/10.1007/s41999-020-00339-6
Wilding, S., Ziauddeen, N., Smith, D., Roderick, P., Chase, D., & Alwan, N. (2020). Are environmental area characteristics at birth associated with overweight and obesity in school-aged children? Findings from the SLOPE (Studying Lifecourse Obesity PrEdictors) population-based cohort in the south of England. BMC Medicine, 18(1), [43]. https://doi.org/10.1186/s12916-020-01513-0
Emmanuel, T., Dall'Ora, C., Ewings, S., & Griffiths, P. (2020). Are long shifts, overtime and staffing levels associated with nurses’ opportunity for educational activities, communication and continuity of care assignments? A cross-sectional study. International Journal of Nursing Studies Advances, 2. https://doi.org/10.1016/j.ijnsa.2020.100002
et al., Do, C. W., Chan, L. Y. L., Tse, A. C. Y., & Lee, P. H. (2020). Association between time spent on smart devices and change in refractive error: a 1-year prospective observational study among Hong Kong children and adolescents. International Journal of Environmental Research and Public Health, 17(23), [8923]. https://doi.org/10.3390/ijerph17238923
et al., Lee, R. L. T., Chien, W. T., Ligot, J., & Lee, P. H. (2020). Associations between quality of life, psychosocial well-being and health-related behaviors among adolescents in Chinese, Japanese, Taiwanese, Thai and the Filipino populations: a cross-sectional survey. International Journal of Environmental Research and Public Health, 17(7), [2402]. https://doi.org/10.3390/ijerph17072402
Taylor, E., Wilding, S., Ziauddeen, N., Godfrey, K., Berrington, A., & Alwan, N. (2020). Change in modifiable maternal characteristics and behaviours between consecutive pregnancies and offspring adiposity: a systematic review. Obesity Reviews, 21(11), [e13048]. https://doi.org/10.1111/obr.13048
Clark, T., Beard, K., Brendish, N., Malachira, A., Mills, S., Chan , C., Poole, S., Ewings, S., Cortes, N., Nyimbili, E., & Presland, L. (2020). Clinical impact of a routine, molecular, point-of-care, test-and-treat strategy for influenza in adults admitted to hospital (FluPOC): a multicentre, open-label, randomised controlled trial. The Lancet Respiratory Medicine, 0, 1-11. https://doi.org/10.1016/S2213-2600(20)30469-0
Brendish, N., Poole, S., Naidu, V., Mansbridge, C., Norton, N., Wheeler, H., Presland, L., Kidd, S., Cortes, N., Borca, F., Phan, H., Babbage, G., Visseaux, B., Ewings, S., & Clark, T. (2020). Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital: a prospective, interventional, non-randomised, controlled study (COV-19POC). The Lancet Respiratory Medicine, 8(12), 1192-1200. https://doi.org/10.1016/S2213-2600(20)30454-9
Griffiths, G. (2020). Clinical trials in oncology. Medicine, 48(2), 128-131. https://doi.org/10.1016/j.mpmed.2019.11.012
Stuart, B., Becque, T., Moore, M., & Little, P. (2020). Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials. BMC Medical Research Methodology, 20(1), [83]. https://doi.org/10.1186/s12874-020-00971-7
Muckelt, P., Roos, E. M., Stokes, M., McDonough, S., Grønne, DT., Ewings, S., & Skou, ST. (Accepted/In press). Comorbidities and their link with individual health status: a cross-sectional analysis of 23,892 people with knee and hip osteoarthritis from primary care. Journal of Comorbidity.
Tse, A. C. Y., Yu, C. C. W., & Lee, P. H. (2020). Comparing sleep patterns between children with autism spectrum disorder and children with typical development: a matched case–control study. Autism, 24(8), 2298-2303. https://doi.org/10.1177/1362361320936827
Williams, S., Sheard, N., Stuart, B., Phan, H. T. T., Borca, F., Wilkinson, T. M. A., Burke, H., Freeman, A., & REACT COVID Investigators (2020). Comparisons of early and late presentation to hospital in COVID-19 patients. Respirology, 26(2), 204-205. https://doi.org/10.1111/resp.13985
Lee, P. H., Marek, J., & Nálevka, P. (2020). Crowdsourced smartphone data reveal altered sleep/wake pattern in quarantined Chinese during the COVID-19 outbreak. Chronobiology International, 37(8), 1181-1190. https://doi.org/10.1080/07420528.2020.1792486
Luthra, S., Salhiyyah, K., Dritsakis, G., Thorne, K. I., Dixon, E., Ohri, S., & Holt, R. I. G. (2020). Diabetes management during cardiac surgery in the UK: a survey. Diabetic Medicine, [e14388]. https://doi.org/10.1111/dme.14388
Clark, T., Brendish, N., Poole, S., Naidu, V., Mansbridge, C., Norton, N., Wheeler, H., Presland, L., & Ewings, S. (2020). Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19. Journal of Infection, 81(4), 607-613. https://doi.org/10.1016/j.jinf.2020.06.051
Frampton, G., Shepherd, J., Pickett, K., Griffiths, G., & Wyatt, J. (2020). Digital tools for the recruitment and retention of participants in randomised controlled trials: A systematic map. Trials, 21, [478]. https://doi.org/10.1186/s13063-020-04358-3
Fenlon, D., Maishman, T., Day, L., Nuttall, J., May, C., Ellis, M., Raftery, J., Turner, L., Fields, J., Griffiths, G., & Hunter, M. S. (2020). Effectiveness of nurse-led group CBT for hot flushes and night sweats in women with breast cancer: results of the MENOS4 randomised controlled trial. Psycho-Oncology, 29(10), 1514-1523. https://doi.org/10.1002/pon.5432
Kwan, R. Y. C., Lee, D., Lee, P. H., Tse, M., Cheung, D. S. K., Thiamwong, L., & Choi, K. S. (2020). Effects of an mHealth brisk walking intervention on increasing physical activity in older people with cognitive frailty: pilot randomized controlled trial. JMIR mHealth and uHealth, 8(7), [16596]. https://doi.org/10.2196/16596
Schünemann, H. J., Ventresca, M., Crowther, M., Briel, M., Zhou, Q., Macbeth, F., Noble, S., Griffiths, G., Garcia, D., Lyman, G. H., DiNisio, M., Iorio, A., Mbuagbaw, L., Neumann, I., Van Es, N., Brouwers, M., Guyatt, G., Streiff, M. B., Marcucci, M., ... Akl, E. A. (2020). Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis. The Lancet Haematology, 7(10), E746-E755. https://doi.org/10.1016/S2352-3026(20)30293-3, https://doi.org/10.1016/S2352-3026(20)30293-3
Fachal, L., Aschard, H., Beesley, J., & et al. (2020). Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52(1), 56-73. https://doi.org/10.1038/s41588-019-0537-1
et al., Abbafati, C., Abbas, K. M., Abbasi-Kangevari, M., & Lee, P. (2020). Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1204-1222. https://doi.org/10.1016/S0140-6736(20)30925-9
et al., Abbafati, C., Abbas, K. M., Abbasi-Kangevari, M., Abdollahi, M., & Lee, P. (2020). Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1223-1249. https://doi.org/10.1016/S0140-6736(20)30752-2
Soilemezi, D., Leydon, G., Yan, R., Simpson, C., Bell, M., Bostock, J., Moore, M., & Willcox, M. (2020). Herbal medicine for acute bronchitis: A qualitative interview study of patients’ and health professionals’ views. Complementary Therapies in Medicine, 55, [102613]. https://doi.org/10.1016/j.ctim.2020.102613
Williams, A., Bate, J., Brooks, R., Clarke, S., Dixon, E., Faust, S., Chisholm, J. C., Galanopoulou, A., Heath, P., Maishman, T., Mapstone, S., Patel, S. R., Vora, A., Wilding, S., & Gray, J. (2020). Immune reconstitution in children following chemotherapy for Acute Lymphoblastic Leukaemia. ejHaem. https://doi.org/10.1002/jha2.27
Grunewald, C. M., Henn, A., Galsky, M. D., Plimack, E. R., Harshman, L. C., Yu, E. Y., Crabb, S. J., Pal, S. K., Alva, A. S., Powles, T., De Giorgi, U., Agarwal, N., Bamias, A., Ladoire, S., Necchi, A., Vaishampayan, U. N., Sternberg, C. N., Bellmunt, J., Baniel, J., & Niegisch, G. (2020). Impact of timing of adjuvant chemotherapy following radical cystectomy for bladder cancer on patient survival. Urologic Oncology, 38(12), 934.e1-934.e9. https://doi.org/10.1016/j.urolonc.2020.06.008
REACT COVID Investigators (2020). Inflammatory phenotyping predicts clinical outcome in COVID-19. Respiratory Research, 21(1), 245. [245]. https://doi.org/10.1186/s12931-020-01511-z
Lown, M., Brown, M., Brown, C., Yue, A. M., Shah, B., Corbett, S., Lewith, G., Stuart, B., Moore, M., & Little, P. (2020). Machine learning detection of atrial fibrillation using wearable technology. PLoS ONE, 15(1), [e0227401]. https://doi.org/10.1371/journal.pone.0227401
et al., Lozano, R., Fullman, N., Mumford, J. E., & Lee, P. (2020). Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1250-1284. https://doi.org/10.1016/S0140-6736(20)30750-9
Sissoko, L., Diarra, N., Nientao, I., Stuart, B., Togola, A., Diallo, D., & Willcox, M. (2020). Moringa oleifera leaf powder for type 2 diabetes: a pilot clinical trial. African Journal of Traditional, Complementary and Alternative Medicines, 17(2), 29-36. https://doi.org/10.21010/ajtcam.v17i2.3
Al-Kaisy, A., Royds, J., Palmisani, S., Pang, D., Wesley, S., Taylor, R., Cook, A., Eldabe, S., McCracken, L., Duarte, R., & Fairbank, J. (2020). Multicentre, double-blind, randomised, sham-controlled trial of 10 kHz high- frequency spinal cord stimulation for chronic neuropathic low back pain (MODULATE-LBP): a trial protocol. Trials, 21(111), [111]. https://doi.org/10.1186/s13063-019-3831-4
et al., Yu, A. P., Ugwu, F. N., Tam, B. T., Lee, P. H., & Siu, P. M. (2020). Obestatin and growth hormone reveal the interaction of central obesity and other cardiometabolic risk factors of metabolic syndrome. Scientific Reports, 10(1), [5495]. https://doi.org/10.1038/s41598-020-62271-w
Ventresca, M., Schünemann, H. J., Macbeth, F., Clarke, M., Thabane, L., Griffiths, G., Noble, S., Garcia, D., Marcucci, M., Iorio, A., Zhou, Q., Crowther, M., Akl, E. A., Lyman, G. H., Gloy, V., DiNisio, M., & Briel, M. (2020). Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide. BMC Medical Research Methodology, 20(113). https://doi.org/10.1186/s12874-020-00964-6
Ellis, J., Band, R., Kinsella, K., Cheetham-Blake, T., James, E., Ewings, S., & Rogers, A. (2020). Optimising and profiling pre-implementation contexts to create and implement a public health network intervention for tackling loneliness. Implementation Science, 15(1), [35]. https://doi.org/10.1186/s13012-020-00997-x
Crabb, S. J., Griffiths, G., Marwood, E., Dunkley, D., Downs, N., Martin, K., Light, M., Northey, J., Wilding, S., Whitehead, A., Shaw, E., Birtle, A. J., Bahl, A., Elliott, T., Westbury, C., Sundar, S., Robinson, A., Jagdev, S., Kumar, S., ... Jones, R. J. (2020). Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2001576. https://doi.org/10.1200/JCO.20.01576
Hornsey, S., Stuart, B., Muller, I., Layton, A. M., Morrison, L., King, J., Thomas, K., Little, P., & Santer, M. (Accepted/In press). Patient reported outcome measures for Acne: a mixed methods validation study (Acne PROMS). BMJ Open.
Kendrick, T., Moore, M., Leydon, G., Stuart, B., Geraghty, A. W. A., Yao, G., Lewis, G., Griffiths, G., May, C., Dewar-Haggart, R., Williams, S., Zhu, S., & Dowrick, C. (2020). Patient-reported outcome measures for monitoring primary care patients with depression (PROMDEP): study protocol for a randomised controlled trial. Trials, 21(1), 1-13. [441]. https://doi.org/10.1186/s13063-020-04344-9
Faulkner, J., O’Brien, W. J., Mcgrane, B., Wadsworth, D., Batten, J., Askew, C. D., Badenhorst, C., Byrd, E., Coulter, M., Draper, N., Elliot, C., Fryer, S., Hamlin, M. J., Jakeman, J., Mackintosh, K. A., McNarry, M. A., Mitchelmore, A., Murphy, J., Ryan-Stewart, H., ... Lambrick, D. (2020). Physical activity, mental health and well-being of adults during initial COVID-19 containment strategies: A multi-country cross-sectional analysis. Journal of Science and Medicine in Sport . https://doi.org/10.1016/j.jsams.2020.11.016
et al., Yu, B. Y. M., Yeung, W. F., Lam, J. C. S., & Lee, P. H. (2020). Prevalence of sleep disturbances during COVID-19 outbreak in an urban Chinese population: a cross-sectional study. Sleep Medicine, 74(10), 18-24. https://doi.org/10.1016/j.sleep.2020.07.009
Little, P., Ordonez-Mena, J. M., Fanshawe, T. R., Butler, C., Mant, D., Moore, M., & Stuart, B. (2020). Relationship between microbiology of throat swab and clinical course among primary care patients with acute cough: a prospective cohort study. Family Practice, 37(3). https://doi.org/10.1093/fampra/cmz093
Heinz, J., Röver, C., Furaijat, G., Kaußner, Y., Hummers-Pradier, E., Debray, T., Hay, A., Heytens, S., Vik, I., Little, P., Moore, M., Stuart, B., Wagenlehner, F., Kronenberg, P. A., Ferry, S., Monsen, T., Lindbæk, M., Friede, T., & Gágyor, I. (2020). Strategies to reduce antibiotic use in women with uncomplicated urinary tract infection in primary care: protocol of a systematic review and meta-analysis including individual patient data. BMJ Open, 10(10), e035883. https://doi.org/10.1136/bmjopen-2019-035883
Latter, S., Campling, N., Birtwistle, J., Richardson, A., Bennett, M., Ewings, S., Meads, D., & Santer, M. (Accepted/In press). Supporting patient access to medicines in community palliative care on-line survey of health professionals’ practice, perceived effectiveness and influencing factors. BMC Palliative Care, 19, [148 ]. https://doi.org/10.1186/s12904-020-00649-3
McKenzie, H., Maishman, T., Simmonds, P., Durcan, L., Posh Steering Group, Eccles, D., & Copson, E. (2020). Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients. British Journal of Cancer, 122(11), 1618-1629. [CL-2019-6197R ]. https://doi.org/10.1038/s41416-020-0784-z
Chan, C. W., Lee, P. H., Molassiotis, A., & Lee, H. K. K. (2020). Symptom clusters in postchemotherapy neutropenic fever in hematological malignancy: associations among sickness behavior symptom cluster, inflammatory biomarkers of procalcitonin and C-reactive protein, and febrile measures. Journal of Pain and Symptom Management, 59(6), 1204-1211. https://doi.org/10.1016/j.jpainsymman.2019.12.372
Bridgewater, J., Pugh, S. A., Maishman, T., Eminton, Z., Mellor, J. M., Whitehead, A., Stanton, L., Radford, M., Corkhill, A., Griffiths, G., Falk, S., Valle, J., O'Reilly, D., Siriwardena, A. K., Hornbuckle, J., Rees, M., Iveson, T., Hickish, T., Garden, O. J., ... New EPOC investigators (2020). Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trial. The Lancet Oncology, 21(3), 398-411. https://doi.org/10.1016/S1470-2045(19)30798-3
Smith, K., Bradbury, K., Essery, R., Pollet, S., Mowbray, F., Slodkowska-Barabasz, J., Denison-Day, J., Hayter, V., Kelly, J. M., Somerville, J., Zhang, J., Grey, E. B., Western, M., Ferrey, A., Krusche, A., Stuart, B., Mutrie, N., Robinson, S., Guiqing, L., ... Yardley, L. (2020). The active brains digital intervention to reduce cognitive decline in older adults: Protocol for a feasibility randomized controlled trial. JMIR Research Protocols, 9(11), [18929]. https://doi.org/10.2196/18929
Almansour, H. B., Gobbi, M., Prichard, J., & Ewings, S. (2020). The association between nationality and nurse job satisfaction in Saudi Arabian hospitals. International Nursing Review, 67(3), 420-426. https://doi.org/10.1111/inr.12613
Choi, K. Y., Mok, A. Y. T., Do, C. W., Lee, P. H., & Chan, H. H. L. (2020). The diversified defocus profile of the near-work environment and myopia development. Ophthalmic and Physiological Optics, 40(4), 463-471. https://doi.org/10.1111/opo.12698
Molassiotis, A., Suen, L., Lai, C., Chan, B., Wat, K. H. Y., Tang, J., To, K. L., Leung, C. O., Lee, S., Lee, P., & Chien, W. T. (2020). The effectiveness of acupressure in the management of depressive symptoms and in improving quality of life in older people living in the community: a randomised sham-controlled trial. Aging and Mental Health, 24(6), 1001-1009. https://doi.org/10.1080/13607863.2019.1584789
Local Burden of Disease 2019 Neglected Tropical Diseases Collaborators, Deshpande, A., Miller-Petrie, M. K., Johnson, K. B., Nguyen, T. H., Hill, E., Ullah, I., Zhang, Z., & Lee, P. (2020). The global distribution of lymphatic filariasis, 2000–18: a geospatial analysis. The Lancet Global Health, 8(9), e1186-e1194. https://doi.org/10.1016/S2214-109X(20)30286-2
van Es, N., Ventresca, M., Di Nisio, M., Zhou, Q., Noble, S., Crowther, M., Briel, M., Garcia, D., Lyman, G. H., Macbeth, F., Griffiths, G., Iorio, A., Mbuagbaw, L., Neumann, I., Brozek, J., Guyatt, G., Streiff, M. B., Baldeh, T., Florez, I. D., ... IPDMA heparin use in cancer patients research group (2020). The Khorana score for prediction of venous thromboembolism in cancer patients: an individual patient data meta-analysis. Journal of Thrombosis and Haemostasis, 18(8), 1940-1951. https://doi.org/10.1111/jth.14824
Asbun, H., Moekotte, A. L., Vissers, F., & et al. (2020). The Miami International Evidence-Based Guidelines on Minimally Invasive Pancreas Resection. Annals of Surgery, 271(1), 1-14. https://doi.org/10.1097/SLA.0000000000003590
Do, O. A., Ferris, L. A., Holt, S. K., Ramos, J. D., Harshman, L. C., Plimack, E. R., Crabb, S. J., Pal, S. K., De Giorgi, U., Ladoire, S., Baniel, J., Necchi, A., Vaishampayan, U. N., Bamias, A., Bellmunt, J., Srinivas, S., Dorff, T. B., Galsky, M. D., & Yu, E. Y. (2020). Treatment of metastatic urothelial carcinoma after previous cisplatin-based chemotherapy for localized disease: A retrospective comparison of different chemotherapy regimens. Clinical Genitourinary Cancer. https://doi.org/10.1016/j.clgc.2020.10.006
Kwong, E. W. Y., Chen, L. Y., Kwan, R. Y. C., & Lee, P. H. (2020). 私人民营疗养院助理护士的压力伤害预防方案的效果:组群随机对照试验. Journal of Advanced Nursing, 76(7), 1780-1793. https://doi.org/10.1111/jan.14391
Chan, K., Wong, F. K. Y., & Lee, P. H. (2019). A brief hope intervention to increase hope level and improve well-being in rehabilitating cancer patients: a feasibility test. SAGE Open Nursing, 5. https://doi.org/10.1177/2377960819844381
Hunter, M. S., Nuttall, J., & Fenlon, D. (2019). A comparison of three outcome measures of the impact of vasomotor symptoms on women’s lives. Climacteric, 22(4), 419-423. https://doi.org/10.1080/13697137.2019.1580258
Hughes, J. G., Leydon, G. M., Watts, S., Hughes, S., Brindle, L. A., Arden‐close, E., Bacon, R., Birch, B., Carballo, L., Plant, H., Moore, C. M., Stuart, B., Yao, G., Lewith, G., & Richardson, A. (2019). A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance. Cancer Reports, 1-8. https://doi.org/10.1002/cnr2.1230
Hay, A. D., Downing, H., Francis, N. A., Young, G. J., Clement, C., Harris, S. D., Ahern, A., Schofield, B., Thomas, T. E., Horwood, J., Blair, P. S., Hollingworth, W., Wilson, V., Metcalfe, C., Stoddart, P., Nunez, D., Lyttle, M. D., Little, P., & Moore, M. V. (2019). Anaesthetic-analgesic ear drops to reduce antibiotic consumption in children with acute otitis media: the CEDAR RCT. Health Technology Assessment, 23(34), 1-48. https://doi.org/10.3310/hta23340

Conference

Davies, A., Mckay, P., Osborne, W., Stanton, L., Tansley‐hancock, O., Lawrence, M., Mercer, K., Allen, A., Pottinger, B., Zhelyazkova, A., Miall, F., Rafferty, J., Sale, B., Cucco, F., Nunn, L., Coleman, A., Griffiths, G., Du, M. Q., Burton, C., ... Johnson, P. (2021). 9p gain predicts outcomes in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) treated with R-GemOx +/- Atezolizumab. ARGO: a randomised phase II study. Hematological Oncology, 39(S2), 155 - 156. https://doi.org/10.1002/hon.11_2880

Letters/Editorials

Lee, U., & Lee, P. H. (2022). Editorial: Adverse health consequences of excessive smartphone usage, volume II. Frontiers in Public Health, 10, [984398]. https://doi.org/10.3389/fpubh.2022.984398
Vancheeswaran, R., Willcox, M. L., Stuart, B., Knight, M., Kandil, H., Barlow, A., Patel, M. H., Stockham, J., O'Neill, A., Clark, T. W., Wilkinson, T., Little, P., Francis, N., Griffiths, G., & Moore, M. (2021). Accuracy of rapid point-of-care antibody test in patients with suspected or confirmed COVID-19. Journal of Infection, 84(1), 94-118. https://doi.org/10.1016/j.jinf.2021.07.006
Stuart, B., Little, P., Moore, M., & Francis, N. (2021). Authors' reply to Bradley. The BMJ, 373, n1518. [n1518]. https://doi.org/10.1136/bmj.n1518
Lee, P. H. (2021). Editorial: Adverse health consequences of excessive smartphone usage. Frontiers in Public Health, 9, [689968]. https://doi.org/10.3389/fpubh.2021.689968
Horwood, J., Chalder, M., Ainsworth, B., Denison-Day, J., de Vocht, F., Elwenspoek, M. M. C., Craggs, P., Denholm, R., Sterne, J., Rice, C., Miller, S. J., Stuart, B., Little, P., Moore, M., Willcox, M., Macleod, J., Gullford, M., Morton, K., Towler, L., ... Yardley, L. (2021). Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial. Trials, 22(1), [263]. https://doi.org/10.1186/s13063-021-05188-7
Lee, P. H. (2020). Sample sizes in COVID-19–related research. CMAJ, 192(17), [E461]. https://doi.org/10.1503/cmaj.75308
Lee, P. H. (2020). The quality of the reported sample size calculation in clinical trials on COVID-19 patients indexed in PubMed. European Journal of Internal Medicine, 77(7), 139-140. https://doi.org/10.1016/j.ejim.2020.04.057

Report

Latter, S., Campling, N., Birtwistle, J., Richardson, A., Bennett, M. I., Meads, D., Blenkinsopp, A., Breen, L., Edwards, Z., Sloan, C., Miller, E., Ewings, S., Santer, M., & Roberts, L. (2022). Improving access to medicines to support palliative care at home: challenges and opportunities. University of Southampton. https://doi.org/10.5258/SOTON/PP0003

Reviews

Geraghty, A., Maund, E., Newell, D., Santer, M., Everitt, H., Price, C. J., Pincus, T., Moore, M., Little, P., West, R., & Stuart, B. (2021). Self-management for chronic widespread pain including fibromyalgia: A systematic review and meta-analysis. PLoS ONE, 16(7 July), [e0254642]. https://doi.org/10.1371/journal.pone.0254642
Clark, B., Whitall, J., Kwakkel, G., Mehrholz, J., Ewings, S., & Burridge, J. (2021). The effect of time spent in rehabilitation on activity limitation and impairment after stroke. Cochrane Database of Systematic Reviews, 2021(10), [CD012612]. https://doi.org/10.1002/14651858.CD012612.pub2
Stuart, B., Maund, E., Wilcox, C., Sridharan, K., Sivaramakrishnan, G., Regas, C., Newell, D., Soulsby, I., Tang, K. F., Finlay, A. Y., Bucher, H. C., Little, P., Layton, A. M., & Santer, M. (2021). Topical preparations for the treatment of mild to moderate acne vulgaris: systematic review and network meta-analysis. British Journal of Dermatology, 185(3), 512-525. https://doi.org/10.1111/bjd.20080
Bundred, J., Michael, S., Bowers, S., Barnes, N., Jauhari, Y., Plant, D., Maishman, T., Cutress, R., Holleczek, B., Dodwell, D., & Bundred, N. (2020). Do surgical margins matter after mastectomy? A systematic review. European Journal of Surgical Oncology, 46(12), 2185-2194. https://doi.org/10.1016/j.ejso.2020.08.015
Kendrick, T., Geraghty, A. W. A., Bowers, H., Stuart, B., Leydon, G., May, C., Yao, G., O'Brien, W., Glowacka, M., Holley, S., Williams, S., Zhu, S., Dewar-Haggart, R., Palmer, B., Bell, M., Collinson, S., Fry, I., Lewis, G., Griffiths, G., ... Dowrick, C. (2020). REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial. Trials, 21(1), 1-15. [419]. https://doi.org/10.1186/s13063-020-04338-7, https://doi.org/10.1186/s13063-020-04338-7
Kwan, R. Y. C., Salihu, D., Lee, P. H., Tse, M., Cheung, D. S. K., Roopsawang, I., & Choi, K. S. (2020). The effect of e-health interventions promoting physical activity in older people: a systematic review and meta-analysis. European Review of Aging and Physical Activity, 17(1), [7]. https://doi.org/10.1186/s11556-020-00239-5