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Miller, S., Yardley, L., Smith, P. W. F., Weal, M., Milton, A. MC., Stuart, B., Little, P., & Morrison, L. (2022). A digital intervention for respiratory tract infections (Internet Dr): process evaluation to understand how to support self-care for minor ailments. JMIR Formative Research , 6(1), [e24239]. https://doi.org/10.2196/24239
Wootton, S., Durkin, K., Heetun, M. A., Ewings, S., Munday, R., Turner, L., Copson, E., & Cutress, R. (2022). Body composition and chemotherapy toxicity in women with early breast cancer (CANDO-3): protocol for an observational cohort study. BMJ Open, 12(2), [e054412]. https://doi.org/10.1136/bmjopen-2021-054412
Cong, W., Chai, J., Zhao, L., Cabral, C., Yardley, L., Yao, G. L., Zhang, T., Cheng, J., Shen, X., Liu, R., Little, P., Stuart, B., Hu, X., Sun, Y-H., Oliver, I., Zheng, B., Lambert, H., & Wang, D. (2022). Cluster randomised controlled trial to assess a tailored intervention to reduce antibiotic prescribing in rural China: study protocol. BMJ Open, 12(1), [e048267]. https://doi.org/10.1136/bmjopen-2020-048267
Griffiths, G. (2022). CONFIRM trial: what is the real efficacy of second-line immunotherapy in mesothelioma? - Authors' reply. Lancet Oncology, 23(1), e14-e15. https://doi.org/10.1016/S1470-2045(21)00722-1
Afolabi, P. R., McDonnell, D., Byrne, C. D., Wilding, S., Goss, V., Walters, J., & Hamady, Z. Z. (2022). DEPEND study protocol: early detection of patients with pancreatic cancer - a pilot study to evaluate the utility of faecal elastase-1 and 13C-mixed triglyceride breath test as screening tools in high-risk individuals. BMJ Open, 12(2), [e057271]. https://doi.org/10.1136/bmjopen-2021-057271
Sharples, L., Sastry, P., Freeman, C., Gray, J., McCarthy, A., Chiu, Y-D., Bicknell, C., McMeekin, P., Vallabhaneni, S. R., Cook, A., Vale, L., & Large, S. (2022). Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study. Health Technology Assessment, 26(6), 1-166. https://doi.org/10.3310/ABUT7744
Lim, S. H., Stuart, B., Joseph-Pietras, D., Johnson, M., Campbell, N., Kelly, A., Jeffrey, D., Turaj, A. H., Rolfvondenbaumen, K., Galloway, C., Wynn, T., Coleman, A. R., Ward, B., Long, K., Coleman, H., Mundy, C., Bates, A. T., Ayres, D., Lown, R., ... Goldblatt, D. (2022). Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study. Nature cancer. https://doi.org/10.1038/s43018-022-00364-3
ORANGE trials collaborative (2022). Laparoscopic versus open resections in the posterosuperior liver segments within an enhanced recovery programme (ORANGE Segments): study protocol for a multicentre randomised controlled trial. Trials, 23(1), 206. [206]. https://doi.org/10.1186/s13063-022-06112-3
Hack, J., & Crabb, S. (2022). Platinum-based chemotherapy ‘Rechallenge’ in advanced non-ovarian solid malignancies. Clinical Oncology. https://doi.org/10.1016/j.clon.2022.02.015
Ewings, S., Saunders, G., Jaki, T., & Mozgunov, P. (2022). Practical recommendations for implementing a Bayesian adaptive phase I design during a pandemic. BMC Medical Research Methodology, 22(1), [25]. https://doi.org/10.1186/s12874-022-01512-0
Hodgson, S., Morgan-Harrisskit, J., Hounkpatin, H., Stuart, B., & Dambha-Miller, H. (2022). Primary care service utilisation and outcomes in type 2 diabetes: a longitudinal cohort analysis. BMJ Open, 12(1), [e054654]. https://doi.org/10.1136/bmjopen-2021-054654
Bancroft, E. K., Page, E. C., Brook, M. N., Thomas, S., Taylor, N., Pope, J., & The IMPACT Study Collaborators (2021). A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study. The Lancet Oncology, 22(11), 1618-1631. https://doi.org/10.1016/S1470-2045(21)00522-2
Patel, S., Ormesher, D., Smith, S., Wong, K., Bevis, P., Bicknell, C., Boyle, J., Brennan, J., Campbell, B., Cook, A., Crosher, A., Duarte, R., Flett, M., Gamble, C., Jackson, R., Juszczak, M., Loftus, I., Norton, I., Patel, J., ... Vallabhaneni, S. R. (2021). A risk-adjusted and anatomically stratified cohort comparison study of open surgery, endovascular techniques and medical management for juxtarenal aortic aneurysms—the UK COMPlex AneurySm Study (UK-COMPASS): a study protocol. BMJ Open. https://doi.org/10.1136/bmjopen-2021-054493
AGILE investigators, Griffiths, G. O., FitzGerald, R., Jaki, T., Corkhill, A., Reynolds, H., Ewings, S., & Condie, S. (2021). AGILE: a seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment: an update to the structured summary of a study protocol for a randomised platform trial letter. Trials, 22, [487 (2021)]. https://doi.org/10.1186/s13063-021-05458-4
AGILE platform (2021). An open label, adaptive, phase 1 trial of high-dose oral nitazoxanide in healthy volunteers: an antiviral candidate for SARS-CoV-2. Clinical Pharmacology and Therapeutics. https://doi.org/10.1002/cpt.2463
Sharples, L., Sastry, P., Freeman, C., Bicknell, C., Chiu, Y-D., Vallabhaneni, S. R., Cook, A., Gray, J., McCarthy, A., McMeekin, P., Vale, L., & Large, S. (2021). Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study. European Heart Journal, 1-14. https://doi.org/10.1093/eurheartj/ehab784
Dambha-Miller, H., Hounkpatin, H., Stuart, B., & Farmer, A. (2021). Association between weight change and remission of type 2 diabetes: a retrospective cohort study in primary care. Practical Diabetes, 38(5), 8-14a. https://doi.org/10.1002/pdi.2355
Hounkpatin, H., Stuart, B., Farmer, A., & Dambha-Miller, H. (Accepted/In press). Association of type 2 diabetes remission and risk of cardiovascular disease in pre-defined subgroups. Endocrinology, Diabetes & Metabolism, 4(3), [e00280]. https://doi.org/10.1002/edm2.280
Santoni, M., Massari, F., Bracarda, S., Procopio, G., Milella, M., De Giorgi, U., Basso, U., Aurilio, G., Incorvaia, L., Martignetti, A., Rizzo, M., Cartenì, G., Grande, E., Matrana, M. R., Crabb, S. J., Vau, N., Sorgentoni, G., Cimadamore, A., Montironi, R., & Battelli, N. (2021). Body mass index in patients treated with cabozantinib for advanced renal cell carcinoma: A new prognostic factor? Diagnostics, 11(1), [138]. https://doi.org/10.3390/diagnostics11010138
Hydes, T., Moore, M., Stuart, B., Kim, M., Su, F., Newell, C., Cable, D., Hales, A., & Sheron, N. (2021). Can routine blood tests be modelled to detect advanced liver disease in the community: model derivation and validation using UK primary and secondary care data. BMJ Open, 11(2), e044952. [e044952]. https://doi.org/10.1136/bmjopen-2020-044952
Zhang, M., Luo, J-L., Sun, Q., Harber, J., Dawson, A. G., Nakas, A., Busacca, S., Sharkey, A. J., Waller, D., Sheaff, M. T., Richards, C., Wells-Jordan, P., Gaba, A., Poile, C., Baitei, E. Y., Bzura, A., Dzialo, J., Jama, M., Le Quesne, J., ... Fennell, D. A. (2021). Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. Nature Communications, 12:1751(1), [1751]. https://doi.org/10.1038/s41467-021-21798-w
Gilbert, F. J., Harris, S., Miles, K. A., Weir-McCall, J., Qureshi, N. R., Rintoul, R. C., Dizdarevic, S., Pike, L., Sinclair, D., Shah, A., Eaton, R., Jones, J., Clegg, A. J., Vitiello, B., Hill, J., Cook, A., Tzelis, D., Vale, L., Brindle, L., ... George, S. (Accepted/In press). Comparative accuracy and cost-effectiveness of dynamic contrast-enhanced computed tomography and positron emission tomography in the characterisation of solitary pulmonary nodules. Thorax, [216948]. https://doi.org/10.1136/thoraxjnl-2021-216948
Hall, N., Eaton, S., Sherratt, F. C., Reading, I., Walker, E., Chorozoglou, M., Beasant, L., Wood, W., Stanton, M., Corbett, H., Rex, D., Hutchings, N. J., Dixon, E., Grist, S., Crawley, E. M., Young, B., & Blazeby, J. M. (2021). CONservative TReatment of Appendicitis in Children – a randomised controlled feasibility Trial (CONTRACT). Archives of Disease in Childhood, 106(8), 764-773. https://doi.org/10.1136/archdischild-2020-320746
Stuart, B., Hounkpatin, H., Becque, T., Yao, G., Zhu, S., Alonso-Coello, P., Altiner, A., Arroll, B., Böhning, D., Bostock, J., Bucher, H. C., Chao, J., De La Poza, M., Francis, N., Gillespie, D., Hay, A. D., Kenealy, T., Löffler, C., McCormick, D. P., ... Little, P. (2021). Delayed antibiotic prescribing for respiratory tract infections: Individual patient data meta-analysis. The BMJ, 373, [n808]. https://doi.org/10.1136/bmj.n808
OCTOPuS Study Group, Holt, R., Barnard-Kelly, K., Dritsakis, G., Thorne, K., Cohen, L., Dixon, E., Patel, M., & Cook, A. (2021). Developing an intervention to optimise the outcome of cardiac surgery in people with diabetes: the OCTOPuS pilot study. Pilot and Feasibility Studies, 7(1), [157]. https://doi.org/10.1186/s40814-021-00887-z
Hu, Y. J., Zhou, X., Wang, S., Willcox, M., Garner, C., Brown, D., Becque, T., Stuart, B., Han, Z., Chang, Q., Moore, M., & Little, P. (2021). Diarrhoea Management using Over-the-counter Nutraceuticals in Daily practice (DIAMOND): a feasibility RCT on alternative therapy to reduce antibiotic use. Pilot and Feasibility Studies, 7(1), [126]. https://doi.org/10.1186/s40814-021-00850-y
Bishop, F., Al-Abbadey, M., Roberts, L., MacPherson, H., Stuart, B., Carnes, D., Fawkes, C., Yardley, L., & Bradbury, K. (2021). Direct and mediated effects of treatment context on low back pain outcome: a prospective cohort study. BMJ Open, 11(5), [e044831]. https://doi.org/10.1136/bmjopen-2020-044831
Long, A. M., Jones, I. H., Knight, M., McNally, J., & BAPS-CASS (2021). Early management of meconium ileus in infants with cystic fibrosis: A prospective population cohort study. Journal of Pediatric Surgery, 56(8), 1287-1292. https://doi.org/10.1016/j.jpedsurg.2021.02.047
FORECAST Investigators (2021). Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial. European Heart Journal, 42(37), 3844-3852. https://doi.org/10.1093/eurheartj/ehab444
McManus, R., Little, P., Stuart, B., Morton, K. S., Raftery, J., Kelly, J. M., Bradbury, K., Zhang, J., Zhu, S., Murray, E., May, C. R., Mair, F., Michie, S., Smith, P. W. F., Band, R., Ogburn, E., Allen, J., Rice, C., Nuttall, J., ... Yardley, L. (2021). Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial. British Medical Journal, 372, [m4858]. https://doi.org/10.1136/bmj.m4858
Ainsworth, B., Miller, S., Denison-Day, J., Stuart, B., Groot, J., Rice, C., Bostock, J., Hu, X., Morton, K., Towler, L., Moore, M., Willcox, M., Chadborn, T., Gold, N., Amlôt, R., Little, P., & Yardley, L. (2021). Improving infection control behavior patterns in the home during the COVID-19 pandemic: an observational study of the web-based behavioral intervention ‘Germ Defence’. Journal of Medical Internet Research, 23(2), [e22197]. https://doi.org/10.2196/22197
International Extranodal Lymphoma Study Group (IELSG) (2021). MATRix-RICE therapy and autologous haematopoietic stem-cell transplantation in diffuse large B-cell lymphoma with secondary CNS involvement (MARIETTA): an international, single-arm, phase 2 trial. The Lancet Haematology, 8(2), e110-e121. https://doi.org/10.1016/S2352-3026(20)30366-5
Stuart, B., Howells, L., Pattinson, R., Chalmers, J. R., Grindlay, D., Rogers, N., Grinich, E., Pawlitschek, T., Simpson, E. L., & Thomas, K. (Accepted/In press). Measurement properties of patient reported outcome measures for eczema control: a systematic review. Journal of the European Academy of Dermatology and Venereology.
Griffiths, G., Fennell, D. A., Ewings, S., Ottensmeier, C., Califano, R., Hanna, G., Hill, K., Danson, S., Steele, N., Nye, M., Johnson, L., Lord, J., Middleton, C., Szlosarek, P. W., Chan, S. W., Darlison, L., & Lester, J. (2021). Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial. Oncology, 22(11), 1530-1540. https://doi.org/10.1016/S1470-2045(21)00471-X
Mukherjee, S., Hurt, C., Radhakrishna, G., Gwynne, S., Bateman, A., Gollins, S., Hawkins, M. A., Canham, J., Grabsch, H. I., Falk, S., Sharma, R. A., Ray, R., Roy, R., Cox, C., Maynard, N., Nixon, L., Sebag-Montefiore, D. J., Maughan, T., Griffiths, G. O., & Crosby, T. D. L. (2021). Oxaliplatin/capecitabine or carboplatin/paclitaxel-based preoperative chemoradiation for resectable oesophageal adenocarcinoma (NeoSCOPE): long-term results of a randomised controlled trial. European Journal of Cancer, 153, 153-161. https://doi.org/10.1016/j.ejca.2021.05.020
Adamson, D., Byrne, A., Porter, C., Blazeby, J., Griffiths, G., Nelson, A., Sewell, B., Jones, M., Svobodova, M., Fitzsimmons, D., Nixon, L., Fitzgibbon, J., Thomas, S., Millin, A., Crosby, T., Staffurth, J., & Hurt, C. (2021). Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial. The Lancet Gastroenterology & Hepatology, 6(4), 292-303. https://doi.org/10.1016/S2468-1253(21)00004-2
Adamson, D., Blazeby, J., Porter, C., Hurt, C., Griffiths, G., Nelson, A., Sewell, B., Jones, M., Svobodova, M., Fitzsimmons, D., Nixon, L., Fitzgibbon, J., Thomas, S., Millin, A., Crosby, T., Staffurth, J., & Byrne, A. (2021). Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT. Health technology assessment (Winchester, England), 25(31). https://doi.org/10.3310/hta25310
Willcox, M., Simpson, C., Wilding, S., Stuart, B., Soilemezi, D., Whitehead, A., Morgan, A., Wrixon, E., Zhu, S., Yao, G., Webley, F., Yan, R., Bostock, J., Bell, M., Griffiths, G., Leydon, G., Little, P., Butler, C., Hay, A. D., & Moore, M. (2021). Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial. BMC Complementary Medicine and Therapies, 21(1), [48]. https://doi.org/10.1186/s12906-021-03206-4
Crabb, S. J., Danson, S., Catto, J. W. F., Hussain, S., Chan, D., Dunkley, D., Downs, N., Marwood, E., Day, L., Saunders, G. N., Light, M., Whitehead, A., Ellis, D., Sarwar, N., Enting, D., Birtle, A. J., Johnson, B., Huddart, R., & Griffiths, G. (2021). Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE). Clinical Cancer Research, 27(7), 1882-1892. https://doi.org/10.1158/1078-0432.CCR-20-3946
Beard, D., Campbell, M., Blazeby, J. M., Carr, A., Weijer, C., Cuthbertson, B. H., Buchbinder, R., Pinkney, T., Bishop, F., Pugh, J., Cousins, S., Harris, I., Lohmander, L. S., Blencowe, N. S., Gilles, K., Probst, P., Brennan, C., Cook, A., Farrar-Hockley, D., ... Cook, J. (2021). Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop. Health Technology Assessment, 25(53). https://doi.org/10.3310/hta25530
Essery, R., Pollet, S., Smith, K., Mowbray, F., Slodkowska-Barabasz, J., Denison-Day, J., Hayter, V., Bradbury, K., Grey, E., Western, M., Milton, A. MC., Hunter, C., Ferrey, A., Muller, A. M., Stuart, B., Mutrie, N., Griffin, S. J., Kendrick, T., Brooker, H., ... Yardley, L. (2021). Planning and optimising a digital intervention to protect older adults’ cognitive health. Pilot and Feasibility Studies, 7(1), [158]. https://doi.org/10.1186/s40814-021-00884-2
Francis, N. A., Stuart, B., Knight, M., Vancheeswaran, R., Oliver, C., Willcox, M., Barlow, A., & Moore, M. (2021). Predictors of clinical deterioration in patients with suspected COVID-19 managed in a virtual hospital' setting: A cohort study. BMJ Open, 11(3), [e045356]. https://doi.org/10.1136/bmjopen-2020-045356
Lown, M., McKeown, S., Stuart, B., Francis, N., Santer, M., Lewith, G., Su, F., Moore, M., & Little, P. (2021). Prescribing of long-term antibiotics to adolescents in primary care: a retrospective cohort study. The British journal of general practice : the journal of the Royal College of General Practitioners, 71(713), e887-e894. https://doi.org/10.3399/BJGP.2021.0332
Calman, L., Turner, J., Fenlon, D. R., Permyakova, N. V., Wheelwright, S., Patel, M. I., Din, A., Winter, J., Richardson, A., Smith, P. W. F., & Foster, C. (2021). Prevalence and determinants of depression up to 5 years after colorectal cancer surgery: results from the ColoREctal Wellbeing (CREW) study. Colorectal Disease. https://doi.org/10.1111/codi.15949
Dambha-Miller, H., Hounkpatin, H., Harrisskitt-Morgan, J., Stuart, B., Fraser, S., & Roderick, P. (2021). Primary care consultations for respiratory tract symptoms during the COVID-19 pandemic: a cohort study including 70 000 people in South West England. Family Practice. https://doi.org/10.1093/fampra/cmab127
Renz, S., Chinnery, F., Stuart, B., Day, L., Muller, I., Soulsby, I., Nuttall, J., Thomas, K., Thomas, K. S., Sach, T., Stanton, L., Ridd, M. J., Francis, N., Little, P., Eminton, Z., Griffiths, G., Layton, A. M., & Santer, M. (2021). Spironolactone for adult female acne (SAFA): protocol for a double-blind, placebo-controlled, phase III randomised study of spironolactone as systemic therapy for acne in adult women. BMJ Open, 11(8), e053876. [e053876]. https://doi.org/10.1136/bmjopen-2021-053876
Muller, I., Stuart, B., Sach, T., Hooper, J., Wilczynska, S., Steele, M., Greenwell, K., Sivyer, K., Yardley, L., Williams, H. C., Chalmers, J. R., Leighton, P., Howells, L. M., Ridd, M. J., Lawton, S., Griffiths, G., Nuttall, J., Langan, S. M., Roberts, A., ... Santer, M. (2021). Supporting self-care for eczema: protocol for two randomised controlled trials of ECO (Eczema Care Online) interventions for young people and parents/carers. BMJ Open, 11(2), 1-8. [045583]. https://doi.org/10.1136/bmjopen-2020-045583
Ip, A., Muller, I., Geraghty, A., Rumsby, K., Stuart, B., Little, P., & Santer, M. (2021). Supporting self-management among young people with acne vulgaris through a web-based behavioral intervention: development and feasibility randomized controlled trial. JMIR Dermatology, 4(2), [2]. https://doi.org/10.2196/25918
McCarthy, A., Gray, J., Sastry, P., Sharples, L., Vale, L., Cook, A., McMeekin, P., Freeman, C., Catarino, P., & Large, S. (2021). Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms. BMJ Open, 11(3), [e043323]. https://doi.org/10.1136/bmjopen-2020-043323
Bruyndonckx, R., Stuart, B., Little, P., Hens, N., Ieven, M., Butler, C. C., Verheij, T. J. M., Goossens, H., & Coenen, S. (2021). The effect of amoxicillin in adult patients presenting to primary care with acute cough predicted to have pneumonia or a combined viral-bacterial infection. Antibiotics, 10(7), [817]. https://doi.org/10.3390/antibiotics10070817
Holt, R. I. G., Dritsakis, G., Barnard-Kelly, K., Thorne, K., Whitehead, A., Cohen, L., Dixon, E., Patel, M., Newland-Jones, P., Green, M., Partridge, H., Luthra, S., Ohri, S., Salhiyyah, K., Lord, J., Niven, J., & Cook, A. (2021). The Optimising Cardiac Surgery ouTcOmes in People with diabeteS (OCTOPuS) randomised controlled trial to evaluate an outpatient pre-cardiac surgery diabetes management intervention: a study protocol. BMJ Open, 11(6), e050919. [050919]. https://doi.org/10.1136/bmjopen-2021-050919
Whicher, C. A., Price, H. C., Phiri, P., Rathod, S., Barnard-Kelly, K., Kandala, N. I. I., Thorne, K., Asher, C., Peveler, R., McCarthy, J., & Holt, R. (2021). The use of liraglutide 3.0 mg daily in the management of overweight and obesity in people with schizophrenia, schizoaffective disorder and first episode psychosis: results of a pilot randomised double-blind placebo-control trial. Diabetes, Obesity and Metabolism, 23(6), 1262-1271. https://doi.org/10.1111/dom.14334
Stuart, B., Maund, E., Wilcox, C., Sridharan, K., Sivaramakrishnan, G., Regas, C., Newell, D., Soulsby, I., Tang, K. F., Finlay, A. Y., Bucher, H. C., Little, P., Layton, A. M., & Santer, M. (2021). Topical preparations for the treatment of mild to moderate acne vulgaris: systematic review and network meta-analysis. British Journal of Dermatology, 185(3), 512-525. https://doi.org/10.1111/bjd.20080
Hounkpatin, H., Woods, C., Lown, M., Stuart, B., & Leydon, G. (Accepted/In press). Understanding general practitioners’ views and experiences of using clinical prediction rules in the management of respiratory infections: a qualitative study. BJGP Open.
Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C., & Day, S. (2021). Utilising benefit-risk assessments within clinical trials—a protocol for the BRAINS project. Trials, 22(68), [68]. https://doi.org/10.1186/s13063-021-05022-0
Hulbert, S., Chivers-seymour, K., Summers, R., Lamb, S., Goodwin, V., Rochester, L., Nieuwboer, A., Rowsell, A., Ewing, S., & Ashburn, A. (2020). ‘PDSAFE’ - a multi-dimensional model of falls-rehabilitation for people with Parkinson’s. A mixed methods analysis of therapists’ delivery and experience. Physiotherapy. https://doi.org/10.1016/j.physio.2020.08.006
Irvine, A., Waise, S., Green, E., & Stuart, B. (Accepted/In press). A non-linear optimisation method to extract summary statistics from Kaplan-Meier survival plots using the published P value. BMC Medical Research Methodology.
Davies, A., Mansbridge, C., Simmonds, P., Murray, N., Stanton, L., Chinnery, F., Archer, C., Barrett-Lee, P., Hickish, T., & Crabb, S. (2020). A phase 2 open-label study of carboplatin in combination with gemcitabine as a dose-dense schedule in patients with locally advanced or metastatic breast cancer that are resistant to anthracyclines and taxanes. F1000 Research. https://f1000research.com/articles/9-4
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., Evans, L., Lester, J., Jagdev, S., Casbard, A., Huang, C., Madden, T-A., & Griffiths, G. (2020). A randomised phase II trial of carboplatin and gemcitabine +/- vandetanib in first line treatment of advanced urothelial cell cancer patients not suitable to receive cisplatin. BJU International, 126(2), 292-299. https://doi.org/10.1111/bju.15096
Davies, A., Barrans, S., Burton, C., Caddy, J., Day, L. S., Fernando, D. L., Chinnery, F., Ardeshna, K., Collins, G., Radford, J., Rule, S., McMillan, A., Johnson, P., & Griffiths, G. (2020). ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial. F1000 Research, 9, [941]. https://doi.org/10.12688/f1000research.22318.1
Tom, W., Dixon, R., Page, C., Carroll, M., Griffiths, G., Ho, L-P., De Soyza, A., Felton, T., Lewis, K. E., Phekoo, K., Chalmers, J. D., Gordon, A., McGarvey, L., Doherty, J., Read, R. C., Shankar-Hari, M., Martinez-Alier, N., O'Kelly, M., Duncan, G., ... Singh, D. (2020). ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial. Springer Nature. https://doi.org/10.1186/s13063-020-04584-9
Smith, K., Bradbury, K., Essery, R., Pollet, S., Mowbray, F., Slodkowska-Barabasz, J., Denison-Day, J., Hayter, V., Kelly, J. M., Somerville, J., Zhang, J., Grey, E. B., Western, M., Ferrey, A., Krusche, A., Stuart, B., Mutrie, N., Robinson, S., Guiqing, L., ... Yardley, L. (Accepted/In press). Active Brains - a digital intervention to reduce cognitive decline in older adults: protocol for a feasibility randomised control trial. JMIR Research Protocols, 9(11), [18929]. https://doi.org/10.2196/18929
Griffiths, G., Fitzgerald, R., Jaki, T., Corkhill, A., Marwood, E., Reynolds, H., Stanton, L., Ewings, S., Condie, S., Wrixon, E., Norton, A., Radford, M., Yeats, S., Robertson, J., Darby-Dowman, R., Walker, L., Khoo, S., & UK NIHR community (2020). AGILE-ACCORD: a randomized, multicentre, seamless, adaptive phase I/II platform study to determine the optimal dose, safety and efficacy of multiple candidate agents for the treatment of COVID-19: a structured summary of a study protocol for a randomised platform trial. Trials, 21(1), 1-3. [544]. https://doi.org/10.1186/s13063-020-04473-1
Wilding, S., Ziauddeen, N., Smith, D., Roderick, P., Chase, D., & Alwan, N. (2020). Are environmental area characteristics at birth associated with overweight and obesity in school-aged children? Findings from the SLOPE (Studying Lifecourse Obesity PrEdictors) population-based cohort in the south of England. BMC Medicine, 18(1), [43]. https://doi.org/10.1186/s12916-020-01513-0
Emmanuel, T., Dall'ora, C., Ewings, S., & Griffiths, P. (2020). Are long shifts, overtime and staffing levels associated with nurses’ opportunity for educational activities, communication and continuity of care assignments: across-sectional study  . International Journal of Nursing Studies Advances. https://doi.org/10.1016/j.ijnsa.2020.100002
Taylor, E., Wilding, S., Ziauddeen, N., Godfrey, K., Berrington, A., & Alwan, N. (2020). Change in modifiable maternal characteristics and behaviours between consecutive pregnancies and offspring adiposity: a systematic review. Obesity Reviews, 21(11), [e13048]. https://doi.org/10.1111/obr.13048
Clark, T., Beard, K., Brendish, N., Malachira, A., Mills, S., Chan , C., Poole, S., Ewings, S., Cortes, N., Nyimbili, E., & Presland, L. (2020). Clinical impact of a routine, molecular, point-of-care, test-and-treat strategy for influenza in adults admitted to hospital (FluPOC): a multicentre, open-label, randomised controlled trial. The Lancet Respiratory Medicine, 0, 1-11. https://doi.org/10.1016/S2213-2600(20)30469-0
Brendish, N., Poole, S., Naidu, V., Mansbridge, C., Norton, N., Wheeler, H., Presland, L., Kidd, S., Cortes, N., Borca, F., Phan, H., Babbage, G., Visseaux, B., Ewings, S., & Clark, T. (2020). Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital: a prospective, interventional, non-randomised, controlled study (COV-19POC). The Lancet Respiratory Medicine, 8(12), 1192-1200. https://doi.org/10.1016/S2213-2600(20)30454-9
Griffiths, G. (2020). Clinical trials in oncology. Medicine, 48(2), 128-131. https://doi.org/10.1016/j.mpmed.2019.11.012
Stuart, B., Becque, T., Moore, M., & Little, P. (2020). Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials. BMC Medical Research Methodology, 20(1), [83]. https://doi.org/10.1186/s12874-020-00971-7
Muckelt, P., Roos, E. M., Stokes, M., McDonough, S., Grønne, DT., Ewings, S., & Skou, ST. (Accepted/In press). Comorbidities and their link with individual health status: a cross-sectional analysis of 23,892 people with knee and hip osteoarthritis from primary care. Journal of Comorbidity.
Beard, D., Campbell, M., Blazeby, J. M., Carr, A., Weijer, C., Cuthbertson, B. H., Buchbinder, R., Pinkney, T., Bishop, F., Pugh, J., Cousins, S., Harris, I., Lomander, L. S., Blencowe, N. S., Gilles, K., Probst, P., Brennan, C., Cook, A., Farrar-Hockley, D., ... Cook, J. (2020). Considerations and methods for placebo controls in surgical trials: state of the art review and ASPIRE guidance. The Lancet. https://doi.org/10.1016/S0140-6736(19)33137-X
Luthra, S., Salhiyyah, K., Dritsakis, G., Thorne, K. I., Dixon, E., Ohri, S., & Holt, R. I. G. (2020). Diabetes management during cardiac surgery in the UK: a survey. Diabetic Medicine, [e14388]. https://doi.org/10.1111/dme.14388
Clark, T., Brendish, N., Poole, S., Naidu, V., Mansbridge, C., Norton, N., Wheeler, H., Presland, L., & Ewings, S. (2020). Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19. Journal of Infection, 81(4), 607-613. https://doi.org/10.1016/j.jinf.2020.06.051
Frampton, G., Shepherd, J., Pickett, K., Griffiths, G., & Wyatt, J. (2020). Digital tools for the recruitment and retention of participants in randomised controlled trials: A systematic map. Trials, 21, [478]. https://doi.org/10.1186/s13063-020-04358-3
Fenlon, D., Maishman, T., Day, L., Nuttall, J., May, C., Ellis, M., Raftery, J., Turner, L., Fields, J., Griffiths, G., & Hunter, M. S. (2020). Effectiveness of nurse-led group CBT for hot flushes and night sweats in women with breast cancer: results of the MENOS4 randomised controlled trial. Psycho-Oncology, 29(10), 1514-1523. https://doi.org/10.1002/pon.5432
Schünemann, H. J., Ventresca, M., Crowther, M., Briel, M., Zhou, Q., Macbeth, F., Noble, S., Griffiths, G., Garcia, D., Lyman, G. H., DiNisio, M., Iorio, A., Mbuagbaw, L., Neumann, I., Van Es, N., Brouwers, M., Guyatt, G., Streiff, M. B., Marcucci, M., ... Akl, E. A. (2020). Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis. The Lancet Haematology, 7(10), E746-E755. https://doi.org/10.1016/S2352-3026(20)30293-3, https://doi.org/10.1016/S2352-3026(20)30293-3
Fachal, L., Aschard, H., Beesley, J., & et al. (2020). Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52(1), 56-73. https://doi.org/10.1038/s41588-019-0537-1
Soilemezi, D., Leydon, G., Yan, R., Simpson, C., Bell, M., Bostock, J., Moore, M., & Willcox, M. (2020). Herbal medicine for acute bronchitis: A qualitative interview study of patients’ and health professionals’ views. Complementary Therapies in Medicine, 55, [102613]. https://doi.org/10.1016/j.ctim.2020.102613
Williams, A., Bate, J., Brooks, R., Clarke, S., Dixon, E., Faust, S., Chisholm, J. C., Galanopoulou, A., Heath, P., Maishman, T., Mapstone, S., Patel, S. R., Vora, A., Wilding, S., & Gray, J. (2020). Immune reconstitution in children following chemotherapy for Acute Lymphoblastic Leukaemia. ejHaem. https://doi.org/10.1002/jha2.27
Grunewald, C. M., Henn, A., Galsky, M. D., Plimack, E. R., Harshman, L. C., Yu, E. Y., Crabb, S. J., Pal, S. K., Alva, A. S., Powles, T., De Giorgi, U., Agarwal, N., Bamias, A., Ladoire, S., Necchi, A., Vaishampayan, U. N., Sternberg, C. N., Bellmunt, J., Baniel, J., & Niegisch, G. (2020). Impact of timing of adjuvant chemotherapy following radical cystectomy for bladder cancer on patient survival. Urologic Oncology, 38(12), 934.e1-934.e9. https://doi.org/10.1016/j.urolonc.2020.06.008
Burke, H., Freeman, A., Cellura, D., Stuart, B. L., Brendish, N. J., Poole, S., Borca, F., Phan, H. T. T., Sheard, N., Williams, S., Spalluto, C. M., Staples, K. J., Clark, T. W., Wilkinson, T. M. A., & REACT COVID Investigators (2020). Inflammatory phenotyping predicts clinical outcome in COVID-19. Respiratory Research, 21(1), [245]. https://doi.org/10.1186/s12931-020-01511-z
Lown, M., Brown, M., Brown, C., Yue, A. M., Shah, B., Corbett, S., Lewith, G., Stuart, B., Moore, M., & Little, P. (2020). Machine learning detection of atrial fibrillation using wearable technology. PLoS ONE, 15(1), [e0227401]. https://doi.org/10.1371/journal.pone.0227401
Sissoko, L., Diarra, N., Nientao, I., Stuart, B., Togola, A., Diallo, D., & Willcox, M. (2020). Moringa oleifera leaf powder for type 2 diabetes: a pilot clinical trial. African Journal of Traditional, Complementary and Alternative Medicines, 17(2), 29-36. https://doi.org/10.21010/ajtcam.v17i2.3
Al-Kaisy, A., Royds, J., Palmisani, S., Pang, D., Wesley, S., Taylor, R., Cook, A., Eldabe, S., McCracken, L., Duarte, R., & Fairbank, J. (2020). Multicentre, double-blind, randomised, sham-controlled trial of 10 kHz high- frequency spinal cord stimulation for chronic neuropathic low back pain (MODULATE-LBP): a trial protocol. Trials, 21(111), [111]. https://doi.org/10.1186/s13063-019-3831-4
Ellis, J., Band, R., Kinsella, K., Cheetham-Blake, T., James, E., Ewings, S., & Rogers, A. (2020). Optimising and profiling pre-implementation contexts to create and implement a public health network intervention for tackling loneliness. Implementation Science, 15(1), [35]. https://doi.org/10.1186/s13012-020-00997-x
Crabb, S. J., Griffiths, G., Marwood, E., Dunkley, D., Downs, N., Martin, K., Light, M., Northey, J., Wilding, S., Whitehead, A., Shaw, E., Birtle, A. J., Bahl, A., Elliott, T., Westbury, C., Sundar, S., Robinson, A., Jagdev, S., Kumar, S., ... Jones, R. J. (2020). Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2001576. https://doi.org/10.1200/JCO.20.01576
Hornsey, S., Stuart, B., Muller, I., Layton, A. M., Morrison, L., King, J., Thomas, K., Little, P., & Santer, M. (Accepted/In press). Patient reported outcome measures for Acne: a mixed methods validation study (Acne PROMS). BMJ Open.
Kendrick, T., Moore, M., Leydon, G., Stuart, B., Geraghty, A. W. A., Yao, G., Lewis, G., Griffiths, G., May, C., Dewar-Haggart, R., Williams, S., Zhu, S., & Dowrick, C. (2020). Patient-reported outcome measures for monitoring primary care patients with depression (PROMDEP): study protocol for a randomised controlled trial. Trials, 21(1), 1-13. [441]. https://doi.org/10.1186/s13063-020-04344-9
Faulkner, J., O’Brien, W. J., Mcgrane, B., Wadsworth, D., Batten, J., Askew, C. D., Badenhorst, C., Byrd, E., Coulter, M., Draper, N., Elliot, C., Fryer, S., Hamlin, M. J., Jakeman, J., Mackintosh, K. A., McNarry, M. A., Mitchelmore, A., Murphy, J., Ryan-Stewart, H., ... Lambrick, D. (2020). Physical activity, mental health and well-being of adults during initial COVID-19 containment strategies: A multi-country cross-sectional analysis. Journal of Science and Medicine in Sport . https://doi.org/10.1016/j.jsams.2020.11.016
Little, P., Ordonez-Mena, J. M., Fanshawe, T. R., Butler, C., Mant, D., Moore, M., & Stuart, B. (2020). Relationship between microbiology of throat swab and clinical course among primary care patients with acute cough: a prospective cohort study. Family Practice, 37(3). https://doi.org/10.1093/fampra/cmz093
Heinz, J., Röver, C., Furaijat, G., Kaußner, Y., Hummers-Pradier, E., Debray, T., Hay, A., Heytens, S., Vik, I., Little, P., Moore, M., Stuart, B., Wagenlehner, F., Kronenberg, P. A., Ferry, S., Monsen, T., Lindbæk, M., Friede, T., & Gágyor, I. (2020). Strategies to reduce antibiotic use in women with uncomplicated urinary tract infection in primary care: protocol of a systematic review and meta-analysis including individual patient data. BMJ Open, 10(10), e035883. https://doi.org/10.1136/bmjopen-2019-035883
Latter, S., Campling, N., Birtwistle, J., Richardson, A., Bennett, M., Ewings, S., Meads, D., & Santer, M. (Accepted/In press). Supporting patient access to medicines in community palliative care on-line survey of health professionals’ practice, perceived effectiveness and influencing factors. BMC Palliative Care.
Geraghty, A., Roberts, L., Hill, J., Foster, N. E., Yardley, L., Hay, E., Stuart, B., Turner, D., Griffiths, G., Webley, F., Durcan, L., Morgan, A., Hughes, S., Bathers, S., Butler-Walley, S., Wathall, S., Mansell, G., Leigh, L., & Little, P. (2020). Supporting self-management of low back pain with an internet intervention in primary care: A protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportBack 2). BMJ Open, 10(8), [e040543]. https://doi.org/10.1136/bmjopen-2020-040543
McKenzie, H., Maishman, T., Simmonds, P., Durcan, L., Posh Steering Group, Eccles, D., & Copson, E. (2020). Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young breast cancer patients. British Journal of Cancer, 122(11), 1618-1629. [CL-2019-6197R ]. https://doi.org/10.1038/s41416-020-0784-z
Bridgewater, J., Pugh, S. A., Maishman, T., Eminton, Z., Mellor, J. M., Whitehead, A., Stanton, L., Radford, M., Corkhill, A., Griffiths, G., Falk, S., Valle, J., O'Reilly, D., Siriwardena, A. K., Hornbuckle, J., Rees, M., Iveson, T., Hickish, T., Garden, O. J., ... New EPOC investigators (2020). Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trial. The Lancet Oncology, 21(3), 398-411. https://doi.org/10.1016/S1470-2045(19)30798-3
Almansour, H. B., Gobbi, M., Prichard, J., & Ewings, S. (2020). The association between nationality and nurse job satisfaction in Saudi Arabian hospitals. International Nursing Review, 67(3), 420-426. https://doi.org/10.1111/inr.12613
van Es, N., Ventresca, M., Di Nisio, M., Zhou, Q., Noble, S., Crowther, M., Briel, M., Garcia, D., Lyman, G. H., Macbeth, F., Griffiths, G., Iorio, A., Mbuagbaw, L., Neumann, I., Brozek, J., Guyatt, G., Streiff, M. B., Baldeh, T., Florez, I. D., ... IPDMA heparin use in cancer patients research group (2020). The Khorana score for prediction of venous thromboembolism in cancer patients: an individual patient data meta-analysis. Journal of Thrombosis and Haemostasis, 18(8), 1940-1951. https://doi.org/10.1111/jth.14824
Asbun, H., Moekotte, A. L., Vissers, F., & et al. (2020). The Miami International Evidence-Based Guidelines on Minimally Invasive Pancreas Resection. Annals of Surgery, 271(1), 1-14. https://doi.org/10.1097/SLA.0000000000003590
Do, O. A., Ferris, L. A., Holt, S. K., Ramos, J. D., Harshman, L. C., Plimack, E. R., Crabb, S. J., Pal, S. K., De Giorgi, U., Ladoire, S., Baniel, J., Necchi, A., Vaishampayan, U. N., Bamias, A., Bellmunt, J., Srinivas, S., Dorff, T. B., Galsky, M. D., & Yu, E. Y. (2020). Treatment of metastatic urothelial carcinoma after previous cisplatin-based chemotherapy for localized disease: A retrospective comparison of different chemotherapy regimens. Clinical Genitourinary Cancer. https://doi.org/10.1016/j.clgc.2020.10.006
Blatch-Jones, A., Nuttall, J., Bull, A., Worswick, L., Mullee, M., Peveler, R., Falk, S., Tape, N. A., Hinks, J., Lane, J. A., Wyatt, J., & Griffiths, G. (Accepted/In press). Using digital tools in the recruitment and retention in randomised controlled trials: Survey of UK Clinical Trial Units and a qualitative study. Trials. https://doi.org/10.21203/rs.2.12497/v2
Hunter, M. S., Nuttall, J., & Fenlon, D. (2019). A comparison of three outcome measures of the impact of vasomotor symptoms on women’s lives. Climacteric, 22(4), 419-423. https://doi.org/10.1080/13697137.2019.1580258
Hughes, J. G., Leydon, G. M., Watts, S., Hughes, S., Brindle, L. A., Arden‐close, E., Bacon, R., Birch, B., Carballo, L., Plant, H., Moore, C. M., Stuart, B., Yao, G., Lewith, G., & Richardson, A. (2019). A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance. Cancer Reports, 1-8. https://doi.org/10.1002/cnr2.1230
Hay, A. D., Downing, H., Francis, N. A., Young, G. J., Clement, C., Harris, S. D., Ahern, A., Schofield, B., Thomas, T. E., Horwood, J., Blair, P. S., Hollingworth, W., Wilson, V., Metcalfe, C., Stoddart, P., Nunez, D., Lyttle, M. D., Little, P., & Moore, M. V. (2019). Anaesthetic-analgesic ear drops to reduce antibiotic consumption in children with acute otitis media: the CEDAR RCT. Health Technology Assessment, 23(34), 1-48. https://doi.org/10.3310/hta23340
Little, P., Stuart, B., Francis, N., Douglas, E., Tonkin-Crine, S., Anthierens, S., Cals, J. W. L., Melbye, H., Santer, M., Moore, M., Coenen, S., Butler, C. C., Hood, K., Kelson, M., Godycki-Cwirko, M., Mierzecki, A., Torres, A., Llor, C., Davies, M., ... Yardley, L. (2019). Antibiotic prescribing for acute respiratory tract infections 12 months after communication and CRP training: a randomized trial. Annals of Family Medicine, 17(2), 125-132. https://doi.org/10.1370/afm.2356
Frampton, G., Shepherd, J., Pickett, K., Griffiths, G., & Wyatt, J. (2019). Approaches For Randomized Controlled Trial Recruitment Or Retention: A Systematic Map. International Journal of Technology Assessment in Health Care, 35(Special Issue S1 (HTA Beyond 2020: Ready for a New Decade?)), 22-23. https://doi.org/10.1017/S0266462319001429, https://doi.org/10.1017/S0266462319001429
Griffiths, G. O., Cowan, R. A., Grigor, K. M., Uscinska, B. M., Sydes, M., & Russell, M. (2019). BA08: An open-label, single-arm, non-randomised, phase 2 trial of cisplatin, methotrexate and vinblastine (CMV) for pure squamous cell cancer of the urinary tract. PLoS ONE, 14(1), [e0210785]. https://doi.org/10.1371/journal.pone.0210785
Johnson, L., Burridge, J., Demain, S., & Ewings, S. (2019). Comparing the impact of an implicit learning approach with standard care on recovery of mobility following stroke: Protocol for a pilot cluster randomized controlled trial. Journal of Medical Internet Research (JMIR) Research Protocols, 8(11), [e14222]. https://doi.org/10.2196/14222
Hall, N., Sherratt, F. C., Eaton, S., Reading, I., Walker, E., Chorozoglou, M., Beasant, L., Wood, W., Stanton, M., Corbett, H., Rex, D., Hutchings, N., Dixon, E., Grist, S., Van't Hoff, W., Crawley, E. M., Blazeby, J. M., & Young, B. (Accepted/In press). Conservative treatment of appendicitis in children: the CONTRACT feasibility randomised controlled trial and mixed methods study. Health Technology Assessment.
Stuart, B., Hounkpatin, H., Becque, T., Yao, L., Zhu, S., Alonso-Coello, P., Altiner, A., Arroll, B., Bohning, D., Bostock, J., Bucher, H. C., Chao, J., De La Poza Abad, M., Francis, NA., Gillespie, D., Hay, A., Kenealy, T., Loffler, C., McCormick, D., ... Little, P. (2019). Delayed antibiotic prescribing for respiratory tract infections: an individual patient data meta-analysis. BMJ Open, 9. https://doi.org/10.1136/bmjopen-2018-026925
Cucco, F., Barrans, S., Clipson, A., Sha, C., Crouch, S., Dobson, R., Chen, Z., Sneath Thompson, J., Care, M., Cummin, T. EC., Caddy, J., Liu, H., Robinson, A., Schuh, A., Fitzgibbon, J., Painter, D., Smith, A., Roman, E., Tooze, R., ... Du, M-Q. (2019). Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit. Leukemia. https://doi.org/10.1038/s41375-019-0691-6
Mahmoudi, M., Nicholas, Z., Nuttall, J., Bresser, M., Maishman, T., Berry, C., Hlatky, M. A., Douglas, P., Rajani, R., Fox, K., & Curzen, N. (2019). Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: rationale and design of the FORECAST trial. Cardiovascular Revascularization Medicine. https://doi.org/10.1016/j.carrev.2019.12.009
Davies, A., Cummin, T., Barrans, S., Maishman, T., Mamot, C., Novak, U., Caddy, J., Stanton, L., Kazmi-Stokes, S., McMillan, A., Fields, P., Pocock, C., Collins, G., Stephens, R., Cucco, F., Clipson, A., Sha, C., Tooze, R., Care, M. A., ... Johnson, P. (2019). Gene expression profiling in an open-label randomised phase 3 trial (REMoDL-B) of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma. The Lancet Oncology, 20(5), 649-662. https://doi.org/10.1016/S1470-2045(18)30935-5, https://doi.org/10.1016/S1470-2045(18)30935-5
NBCS Collaborators (2019). Genome-wide association study of germline variants and breast cancer-specific mortality. British Journal of Cancer, 120(6), 647-657. https://doi.org/10.1038/s41416-019-0393-x
Whitehead, A., Simpson, C., Willcox, M., Webley, F., Hay, A., Butler, C., Yao, L., Wrixon, E., Bell, M., Bostock, J., Little, P., Griffiths, G., & Moore, M. (2019). HATRIC: a study of Pelargonium sidoides root extract EPs®7630 (Kaloba®) for the treatment of acute cough due to lower respiratory tract infection in adults—study protocol for a double blind, placebo-controlled randomised feasibility trial. Pilot and Feasibility Studies, 5(1), [98]. https://doi.org/10.1186/s40814-019-0478-6
Whicher, C. A., Price, H. C., Phiri, P., Rathod, S., Barnard-Kelly, K., Reidy, C., Thorne, K., Asher, C., Peveler, R., McCarthy , J., & Holt, R. I. G. (2019). Liraglutide and the management of overweight and obesity in people with schizophrenia, schizoaffective disorder and first-episode psychosis: protocol for a pilot trial. Trials, 20, 1-10. [633]. https://doi.org/10.1186/s13063-019-3689-5
Mavaddat, N., Durcan, L., Michailidou, K., & et al. (2019). Polygenic risk scores for prediction of breast cancer and breast cancer subtypes. The American Journal of Human Genetics, 104(1), 21-34. https://doi.org/10.1016/j.ajhg.2018.11.002
Cook, J., Julious, S., Sones, W., Hampson, L., Hewitt, C., Berlin, J., Ashby, D., Emsley, R., Fergusson, D., Walters, S. J., Wilson, E., MacLennan, G., Stallard, N., Rothwell, J., Bland, J. M., Brown, L., Ramsay, C., Cook, A., Armstrong, D., ... Vale, L. (2019). Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop. Health Technology Assessment, 23(60), 1-118. https://doi.org/10.3310/hta23600
Gandhi, A., Copson, E., Eccles, D., Durcan, L., Howell, A., Morris, J., Howell, S., McDiarmid, S., Sellers, K., Gareth Evans, D., & Harvie, M. (2019). Predictors of weight gain in a cohort of premenopausal early breast cancer patients receiving chemotherapy. The Breast, 1-6. https://doi.org/10.1016/j.breast.2019.02.006
Bate, J., Borrow, R., Chisholm, J. C., Clarke, S., Dixon, E., Faust, S., Galanopoulou, A., Goldblatt, D., Heath, P. T., Maishman, T., Mapstone, S., Patel, S. R., Williams, A. P., & Gray, J. (2019). Thirteen-valent pneumococcal conjugate vaccine in children with acute lymphoblastic leukemia: Protective immunity can be achieved on completion of treatment. Clinical Infectious Diseases, 71(5), 1271-1280. https://doi.org/10.1093/cid/ciz965
Moore, M., Trill, J., Simpson, C., Webley, F., Radford, M., Stanton, L., Maishman, T., Galanopoulou, A., Flower, A., Eyles, C., Willcox, M., Hay, A. D., van der Werf, E., Gibbons, S., Lewith, G., Little, P., & Griffiths, G. (2019). Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial. Clinical Microbiology and Infection, 1-8. https://doi.org/10.1016/j.cmi.2019.01.011
Gollins, S., West, N., Sebag-Montefiore, D., Susnerwala, S., Falk, S., Brown, N., Saunders, M., Quirke, P., Ray, R., Parsons, P., Griffiths, G., Maughan, T., Adams, R., & Hurt, C. (2018). A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS. British Journal of Cancer, 1-10. https://doi.org/10.1038/s41416-018-0209-4
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Qureshi, N. R., Shah, A., Eaton, R. J., Miles, K., Gilbert, F. J., & Sputnik Investigators (2016). Dynamic contrast enhanced CT in nodule characterization: How we review and report. Cancer imaging : the official publication of the International Cancer Imaging Society, 16(1), 16. https://doi.org/10.1186/s40644-016-0074-4
Kirkpatrick, E., Pearse, J., James, P., & Basu, A. (2016). Effect of parent-delivered action observation therapy on upper limb function in unilateral cerebral palsy: a randomized controlled trial. Developmental Medicine & Child Neurology, 1-8. https://doi.org/10.1111/dmcn.13109
Little, P., Stuart, B., Mullee, M., Thomas, T., Johnson, S., Leydon, G., Rabago, D., Richards-Hall, S., Williamson, I., Yao, L., Raftery, J., Zhu, S., & Moore, M. (2016). Effectiveness of steam inhalation and nasal irrigation for chronic or recurrent sinus symptoms in primary care: a pragmatic randomized controlled trial. Canadian Medical Association Journal, 118(13), 940-949. https://doi.org/10.1503/cmaj.160362
Eccles, D. M., Li, N., Handwerker, R., Maishman, T., Copson, E. R., Durcan, L. T., Gerty, S. M., Jones, L., Evans, D. G., Haywood, L., & Campbell, I. (2016). Genetic testing in a cohort of young patients with HER2 amplified breast cancer. Annals of Oncology, 27(3), 467-73. https://doi.org/10.1093/annonc/mdv592
Cathomas, R., Crabb, S. J., Mark, M., Winterhalder, R., Rothermundt, C., Elliott, T., von Burg, P., Kenner, H., Hayoz, S., Vilei, S. B., Rauch, D., Roggero, E., Mohaupt, M. G., Bernhard, J., Manetsch, G., & Gillessen, S. (2016). Orteronel switch maintenance therapy in metastatic castration resistant prostate cancer after first-line docetaxel: a multicenter, randomized, double-blind, placebo-controlled trial (SAKK 08/11). The Prostate, 76(16), 1519-1527. https://doi.org/10.1002/pros.23236
Arriola, E., Wheater, M., Galea, I., Cross, N., Maishman, T., Hamid, D., Stanton, L., Cave, J., Geldart, T., Mulatero, C., Potter, V., Dansen, S., Woll, P. J., Griffiths, R., Nolan, L., & Ottensmeier, C. (2016). Outcome and biomarker analysis from a multi-centre phase 2 study of ipilimumab in combination with carboplatin and etoposide (ICE) as first line therapy for extensive stage small cell lung cancer. Journal of Thoracic Oncology, 11(9), 1511-1521. https://doi.org/10.1016/j.jtho.2016.05.028
Pugh, S. A., Bowers, M., Ball, A., Falk, S., Finch-Jones, M., Valle, J. W., O'Reilly, D. A., Siriwardena, A. K., Hornbuckle, J., Rees, M., Rees, C., Iveson, T., Hickish, T., Maishman, T., Stanton, L., Dixon, E., Corkhill, A., Radford, M., Garden, O. J., ... Primrose, J. N. (2016). Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study. British Journal of Cancer, 115, 420-424. https://doi.org/10.1038/bjc.2016.208
Wagland, R., Richardson, A., Ewings, S., Armes, J., Lennan, E., Hankins, M., & Griffiths, P. (2016). Prevalence of cancer chemotherapy-related problems, their relation to health-related quality of life, and associated supportive care: a cross-sectional survey. Supportive Care in Cancer, 24(12), 4901-4911. https://doi.org/10.1007/s00520-016-3346-4

Conferences

Wilding, S., Ziauddeen, N., Smith, D., Chase, D., Roderick, P., & Alwan, N. (2019). Associations of area characteristics at birth with overweight and obesity among school-aged children in the south of England: an analysis of a population-based cohort. The Lancet, 394(Supplement 2), S98. https://doi.org/10.1016/S0140-6736(19)32895-8
Nuttall, J., Lane, A., Blatch-Jones, A., Griffiths, G., & Wyatt, J. (2019). Digital tools for more efficient conduct of RCTs: trials unit survey. Trials, 20(Supplement 1), [P-244]. https://doi.org/10.1186/s13063-019-3688-6
Ziauddeen, N., Wilding, S., Roderick, P., Macklon, N., & Alwan, N. (2019). Predicting the risk of childhood overweight and obesity at 4–5 years using pregnancy and early life healthcare data. Journal of Epidemiology & Community Health, 73, [OP38]. https://doi.org/10.1136/jech-2019-SSMabstracts.38
Blatch-Jones, A. J., Bull, A., Nuttall, J., Griffiths, G., & Wyatt, J. (2019). User-focused research to identify the benefits of digital tools for the recruitment and retention in trials: a qualitative study. Trials, 20(Supplment 1), [P-119].
Schunemann, H., Ventresca, M., Crowther, M., Di Nisio, M., Briel, M., Zhou, Q., Noble, S., Macbeth, F., Griffiths, G., Garcia, D., Lyman, G., Iorio, A., Mbuagbaw, L., Neumann, I., Van Es, N., Brozek, J., Guyatt, G., Streiff, M., Brouwers, M., ... Zulian, G. (2017). An individual participant data meta-analysis of 13 randomized trials to evaluate the impact of prophylactic use of heparin in oncological patients. Abstract from 59th ASH Annual Meeting and Exposition, Atlanta, United States.
Davies, A. J., Barrans, S., Maishman, T., Cummin, T. E., Bentley, M., Mamot, C., Novak, U., Caddy, J., Hamid, D., Kazmi-Stokes, S. H., Mcmillan, A., Fields, P. A., Pocock, C., Kruger, A., Collins, G., Sha, C., Clipson, A., Wang, M., Tooze, R. M., ... Johnson, P. W. (2017). Differential efficacy of bortezomib in subtypes of diffuse large B‐cell lymphoma (dlbl): a prospective randomised study stratified by transcriptome profiling: remodl‐B. Hematological Oncology, 35(S2), 130-131. https://doi.org/10.1002/hon.2437_120
Cummin, T. E., Araf, S., Du, M., Barrans, S., Bentley, M. A., Clipson, A., Wang, M., Ahmed, S., Rahim, T., Shah, C., Hamid, D., Dhondt, J., Maishman, T., Vaughan-Spickers, N., Pocock, C., Forbes, A., O'Callaghan, A., Westhead, D. R., Griffiths, G. O., ... Johnson, P. W. (2017). Prognostic significance and correlation to gene expression profile of EZH2 mutations in diffuse large B‐cell lymphoma (DLBL) in 2 large prospective studies. Hematological Oncology, 35(S2), 158-159. https://doi.org/10.1002/hon.2438_13
Van Es, N., Ventresca, M., Zhou, Q., Noble, S., Crowther, M., Di Nisio, M., Briel, M., Garcia, D., Lyman, G., Macbeth, F., Griffiths, G., Iorio, A., Mbuagbaw, L., Neumann, I., Brozek, J., Guyatt, G., Streiff, M., Brouwers, M., Baldeh, T., ... Schunemann, H. (2017). The Khorana Score for the prediction of venous thromboembolism in patients with solid cancer: An individual patient data meta-analysis. Abstract from 59th ASH Annual Meeting and Exposition, Atlanta, United States.

Letters/Editorials

Vancheeswaran, R., Willcox, M. L., Stuart, B., Knight, M., Kandil, H., Barlow, A., Patel, M. H., Stockham, J., O'Neill, A., Clark, T. W., Wilkinson, T., Little, P., Francis, N., Griffiths, G., & Moore, M. (2021). Accuracy of rapid point-of-care antibody test in patients with suspected or confirmed COVID-19. Journal of Infection, 84(1), 94-118. https://doi.org/10.1016/j.jinf.2021.07.006
Stuart, B., Little, P., Moore, M., & Francis, N. (2021). Authors' reply to Bradley. The BMJ, 373, n1518. [n1518]. https://doi.org/10.1136/bmj.n1518
Horwood, J., Chalder, M., Ainsworth, B., Denison-Day, J., de Vocht, F., Elwenspoek, M. M. C., Craggs, P., Denholm, R., Sterne, J., Rice, C., Miller, S. J., Stuart, B., Little, P., Moore, M., Willcox, M., Macleod, J., Gullford, M., Morton, K., Towler, L., ... Yardley, L. (2021). Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial. Trials, 22(1), [263]. https://doi.org/10.1186/s13063-021-05188-7
Cook, A. (2019). Commentary on Curtis et al. Clinical Trials, 16(4), 438-439. https://doi.org/10.1177/1740774519845680
Djebbari, F., Browning, J. A., Stanton, L., Booth, S., Hildyard, C., Willan, J., Bosworth, J., Vora, S. M., Hatton, C. S. R., Collins, G. P., & Eyre, T. A. (2019). Efficacy of R-GCVP in patients with late relapse of diffuse large B-cell lymphoma. British Journal of Haematology. https://doi.org/10.1111/bjh.16071
Papadakis, E. S., Reeves, T., Robson, N. H., Maishman, T., Packham, G., & Cutress, R. I. (2018). Reply to ‘Comment on ‘BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses''. British Journal of Cancer, 118(1154), 1. https://doi.org/10.1038/s41416-018-0032-y

Reviews

Geraghty, A., Maund, E., Newell, D., Santer, M., Everitt, H., Price, C. J., Pincus, T., Moore, M., Little, P., West, R., & Stuart, B. (2021). Self-management for chronic widespread pain including fibromyalgia: A systematic review and meta-analysis. PLoS ONE, 16(7 July), [e0254642]. https://doi.org/10.1371/journal.pone.0254642
Clark, B., Whitall, J., Kwakkel, G., Mehrholz, J., Ewings, S., & Burridge, J. (2021). The effect of time spent in rehabilitation on activity limitation and impairment after stroke. Cochrane Database of Systematic Reviews, 2021(10), [CD012612]. https://doi.org/10.1002/14651858.CD012612.pub2
Bundred, J., Michael, S., Bowers, S., Barnes, N., Jauhari, Y., Plant, D., Maishman, T., Cutress, R., Holleczek, B., Dodwell, D., & Bundred, N. (2020). Do surgical margins matter after mastectomy? A systematic review. European Journal of Surgical Oncology, 46(12), 2185-2194. https://doi.org/10.1016/j.ejso.2020.08.015
Kendrick, T., Geraghty, A. W. A., Bowers, H., Stuart, B., Leydon, G., May, C., Yao, G., O'Brien, W., Glowacka, M., Holley, S., Williams, S., Zhu, S., Dewar-Haggart, R., Palmer, B., Bell, M., Collinson, S., Fry, I., Lewis, G., Griffiths, G., ... Dowrick, C. (2020). REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial. Trials, 21(1), 1-15. [419]. https://doi.org/10.1186/s13063-020-04338-7, https://doi.org/10.1186/s13063-020-04338-7