The HR-MAS NMR probe allows 1 H and 13 C NMR spectroscopy to be used for structure elucidation and reaction monitoring on gel-phase and solid biological samples.
In solid-phase organic synthesis, compounds are immobilised on resin supports and as a consequence constraints are placed on the analytical techniques that are available. The HR-MAS NMR probe allows 1 H and 13 C NMR spectroscopy to be used to follow reactions without removing the substrate from the support.
The HR-MAS probe can also be used to acquire data from solid biological samples such as C. Elegans nematode worms.