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The University of Southampton
The NMR Spectroscopy FacilityCapabilities



The 1D NMR spectra of the alkaloid poison strychnine are relatively complicated with several areas of overlapping signals. The molecule is often used as a standard to test advanced 2D NMR experiments.

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Data Collection

Bruker DPX400/2 FT-NMR spectrometer (legacy)

5 mm DUL-C-H probe

HH COSY. The HH COSY spectrum shows the proton coupling network within the molecule.
HMQC. In the HMQC spectrum the one-bond direct HC couplings can be viewed as cross-peaks between the proton and carbon projections.
HMBC. In the HMBC spectrum the two- and three- bond couplings between protons and carbons can be seen as cross-peaks.
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