Professor V Hugh Perry BSc, MA, DPhil.

Emeritus Professor of Experimental Neuropathology

Professor V Hugh Perry is Emeritus Professor of Experimental Neuropathology within Biological Sciences at the University of Southampton.

Career history

2018 -present: Honorary Consultant and Theme Lead in Neuroinflammation, Dementia Research Institute, University College London.
2018-present: Emeritus Professor of Experimental Neuropathology. University of Southampton, UK.
2012-2017: Chair of Neuroscience and Mental Health Board. MRC, UK.
2011-present: Visiting Professor in the College of Medicine & Veterinary Medicine. University of Edinburgh, UK.
1998-2018: Professor of Experimental Neuropathology. University of Southampton, UK.
1996-1998: Professor of Experimental Neuropathology. University of Oxford, UK.
1986-1995: Wellcome Trust Senior Research Fellow, UK.
1982-1986: Locke Royal Society Research Fellow, UK.
1977-1982: Research Fellow. University of Oxford, UK.

Research

Publications

Contributions

Contact

Research interests

Inflammation in the CNS and its contribution to neurological Disease

The role of microglia in health and disease

The role of systemic inflammation in Alzheimer’s disease and other neurodegenerative diseases

Immune brain communication

Affiliate research groups

Institute for Life Sciences (IfLS), Southampton Neuroscience Group (SoNG)

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Articles

Book Chapters

Perry, V. H. (2017). Microglia. In S. Gordon (Ed.), Myeloid Cells in Health and Disease: A Synthesis (pp. 225-233). (ASM Books). Wiley. https://doi.org/10.1128/9781555819194.ch12
Gomez-Nicola, D., & Perry, V. H. (2014). Neurodegenerative diseases. In M-E. Tremblay, & A. Sierra (Eds.), Microglia in Health and Disease (pp. 437-453). Springer.
Fabriek, B. O., Galea, I., Perry, V. H., & Dijkstra, C. D. (2005). Cerebral perivascular macrophages and the blood brain barrier. In E. de Vries, & A. Prat (Eds.), The Blood-Brain Barrier and its Microenvironment: Basic Physiology to Neurological Disease Informa Healthcare.

Conferences

Letters/Editorials

et al., O'Connor, R. C., Hotopf, M., Worthman, C. M., & Perry, V. H. (2020). Multidisciplinary research priorities for the COVID-19 pandemic – Authors' reply. The Lancet Psychiatry, 7(7), e44-e45. https://doi.org/10.1016/S2215-0366(20)30247-9
Perry, V. H. (2018). Microglia and major depression: not yet a clear picture. Lancet Psychiatry, 5(4), 292-294. https://doi.org/10.1016/S2215-0366(18)30087-7

Reviews

Lauwers, E., Lalli, G., Brandner, S., Collinge, J., Compernolle, V., Duyckaerts, C., Edgren, G., Haïk, S., Hardy, J., Helmy, A., Ivinson, A. J., Jaunmuktane, Z., Jucker, M., Knight, R., Lemmens, R., Lin, I. C., Love, S., Mead, S., Perry, V. H., ... De Strooper, B. (2020). Potential human transmission of amyloid β pathology: surveillance and risks. The Lancet Neurology, 19(10), 872-878. https://doi.org/10.1016/S1474-4422(20)30238-6
Vauzour, D., Camprubi-Robles, M., Miquel-Kergoat, S., Andres-Lacueva, C., Bánáti, D., Barberger-Gateau, P., Bowman, G. L., Caberlotto, L., Clarke, R., Hogervorst, E., Kiliaan, A. J., Lucca, U., Manach, C., Minihane, A-M., Mitchell, E. S., Perneczky, R., Perry, H., Roussel, A. M., Schuermans, J., ... Ramirez, M. (2017). Nutrition for the ageing brain: Towards evidence for an optimal diet. Ageing Research Reviews, 35, 222-240. https://doi.org/10.1016/j.arr.2016.09.010
Vargas-Caballero, M., Willaime-Morawek, S., Gomez-Nicola, D., Perry, V. H., Bulters, D., & Mudher, A. (2016). The use of human neurons for novel drug discovery in dementia research. Expert Opinion on Drug Discovery, 1-35. https://doi.org/10.1517/17460441.2016.1154528
Caleo, M., Restani, L., & Hugh Perry, V. (2013). Silencing synapses: A route to understanding synapse degeneration in chronic neurodegenerative disease. PRION, 7(2), 147-150. https://doi.org/10.4161/pri.23327
Galea, I., Bechmann, I., & Perry, V. H. (2007). What is immune privilege (not)? Trends in Immunology, 28(1), 12-18. https://doi.org/10.1016/j.it.2006.11.004
Bechmann, I., Galea, I., & Perry, V. H. (2007). What is the blood-brain barrier (not)? Trends in Immunology, 28(1), 5-11. https://doi.org/10.1016/j.it.2006.11.007

Professional Affiliations

Chair Neuroscience and Mental Health Board, Medical Research Council, UK
Editorial Boards of a number of journals
Ad hoc consultant to Biotech and Pharma

Professor V Hugh Perry
Biological Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

UCL Email: hugh.perry@ucl.ac.uk

Email: V.H.Perry@soton.ac.uk

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