New grants to boost research into dementia
Scientists at the Centre for Biological Sciences and Medicine at the University of Southampton are working together on two new projects investigating the role of inflammation in dementia, financed by the Medical Research Council and the pharmaceutical company MedImmune.
Dr Jessica Teeling and Professor Hugh Perry from Biological Sciences and Professor Clive Holmes from Clinical and Experimental Sciences have been awarded a total of £170,000 to further their many years of research into the role of systemic inflammation in the onset and progression of age-related neurodegeneration.
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They will be examining the role of cytokines in blood circulation and the brain and exploring if drugs that block these cytokines will protect against neuroinflammation and degeneration, These results may be beneficial for patients with Alzheimer’s Disease, who deteriorate after suffering from bouts of systemic bacterial and viral infections or similar conditions.
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Professor Jessica L. Teeling PhD
Jessica L. Teeling is a Professor in Experimental Neuroimmunology within Biological Sciences at the University of Southampton.
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Professor Clive Holmes BSc, MB, ChB, MRCPsych, PhD
Professor Clive Holmes is Professor of Biological Psychiatry within Medicine at the University of Southampton with a focus on research on the biological factors that alter the clinical course of Alzheimer’s Disease and other related chronic neurodegenerative conditions but with a focus on the role of inflammation. This includes a better understanding of the factors that determine the rate of cognitive decline and the development of neuropsychiatric features. Professor Holmes also leads a clinical trials unit that examines the effects of pharmacological interventions of patients with Alzheimer’s Disease and related conditions. He has had a key role in developing a better understanding of immunomodulatory drugs in Alzheimer’s Disease including the role of drugs such as Etanercept that target systemic innate immunity.
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Professor V Hugh Perry BSc, MA, DPhil.
Professor V Hugh Perry is Emeritus Professor of Experimental Neuropathology within Biological Sciences at the University of Southampton.
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