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The University of Southampton
Histochemistry Research Unit

Clinical trials

The HRU has over 15 years experience in co-ordinating clinical trials using both paraffin and GMA techniques. These studies have included single-centred studies and multi-centred studies in the UK, Europe and USA, some with over 100 subjects.

The facilities within the HRU are at audit standard and the staff are all trained in GCP and are familiar with working according to GLP guidelines. We can offer a complete service including an academic input into protocol design, preparation of operating procedures and training of clinical centres on sample handling.

Examples of studies include:

* NN Jarjour, SJ Wilson, SM Koenig, M Laviolette, WC Moore, WB Davis, DE Doherty, Q Hamid, E Israel, MS Kavuru, JW Ramsdell, DP Tashkin, DS Reilly, SW Yancey, LD Edwards, JL Stauffer, PM Dorinsky, R Djukanovic. Control of Airway Inflammation Maintained at a Lower Steroid Dose with Fluticasone Propionate/Salmeterol 100/50mcg. J Allergyc Clin Immunol 2006;118:44-52.

* Djuaknovic R, Wilson SJ, Kraft M, Jarjour NN, Steel M, Chung KF, Bao W, Fowler-Taylor A, Matthews J, Bussse W, Holagte ST, Fahy JV. Effects of treatment with anti-immunoglobulin E antibody Omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med 2004;170:583-593.

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